CN102357155A - Traditional Chinese medicine combination for treating herpes zoster - Google Patents

Traditional Chinese medicine combination for treating herpes zoster Download PDF

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CN102357155A
CN102357155A CN2011103306547A CN201110330654A CN102357155A CN 102357155 A CN102357155 A CN 102357155A CN 2011103306547 A CN2011103306547 A CN 2011103306547A CN 201110330654 A CN201110330654 A CN 201110330654A CN 102357155 A CN102357155 A CN 102357155A
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chinese medicine
herpes zoster
pain
radix
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CN102357155B (en
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潘根起
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Abstract

The invention belongs to the technical filed of traditional Chinese medicine, particularly discloses a traditional Chinese medicine combination for treating herpes zoster, and is prepared by the following raw materials by weight: 6-15 parts of honeysuckle, 10-30 parts of dandelion, 15-30 parts of Philippine violet herb, 10-15 parts of folium isatidis, 3-6 parts of gentian, 3-10 parts of scutellaria baicalensis, 3-10 parts of fructus gardeniae, 6-12 parts of great burdock achene, 3-10 parts of bupleurum, 3-10 parts of rhizoma corydalis, 3-9 parts of radix aconiti preparata, 1-3 parts of centipede, 3-9 parts of carthamus tinctorius, 3-10 parts of frankincense and 10-15 parts of plantain seeds. The traditional Chinese medicine combination for treating the herpes zoster has effects of clearing away liver-fire, detoxifying and removing dampness, promoting blood circulation and removing obstruction in channels, regulating vital energy and relieving pain, can effectively detoxify and relieve pain, and avoids problems of long-time pain and delayed healing.

Description

A kind of Chinese medicine composition of treating herpes zoster
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of Chinese medicine composition of treating herpes zoster.
Background technology
Herpes zoster belongs to motherland's medical science " herpes zoster " category.Have another name called herpes zoster or claim herpes zoster, herpes zoster.Cry again in " surgery opens profound volume seven " " herpes zoster " and says: " this skin ulcer is born between skin, and is similar with the water nest, light red and bitterly, five or six one-tenth are collected together, and also can shade opens ".Its pathogenesis is: because depression of liver-QI, for a long time and fire-transformation, it is long-pending that the Liver Channel fire-toxin accumulates, excessive skin and the herpes of life; Or impression poison is evil, and damp and hot poison accumulates, and causes coagulation of QI-blood, meridians blocking barrier, so that sharp ache such as fire burn, and with the passing of time could disappear.Some patient leaves over pain symptom and is 1 to 2 year, even more of a specified duration.Its characteristics are: skin erythema, blisters or herpes mound, numerous such as beads, arranged in a strip along the side of the peripheral nerve distribution area appears, local irritation or with Xing nuclear enlargement.Its position is mainly in breast side of body portion, also is found in face or abdominal part etc.
Herpes zoster belongs to viral infectious, and herpesvirus is invaded the neural pain that causes with hiding in dorsal root spinal ganglion neuron or cranial nerve sensory nerve ganglion neuron as burning like fire.But up to now, still there is not specific antiviral Western medicine.So use the Western medicine symptomatic treatment merely, effect is not remarkable, makes patient Yi Liu pain sequela, suffers untold misery.
Summary of the invention
For overcoming the weak point that exists in the prior art, the object of the present invention is to provide a kind of Chinese medicine composition of treating herpes zoster.Said composition has the effect of letting out liver-fire, detoxification and promoting urination, promoting blood circulation to remove obstruction in the collateral, regulating QI to relieve pain clearly.Said composition effectively pain relieving is passed through poison, has avoided leaving over the drawback that pain of a specified duration does not heal again.For the treatment herpes zoster provides an effective way and method.
For realizing above-mentioned purpose, the technical scheme that the present invention takes is following:
A kind of Chinese medicine composition of treating herpes zoster is processed by each crude drug of following portions by weight: 6 ~ 15 parts of Flos Loniceraes, 10 ~ 30 parts of Herba Taraxacis, 15 ~ 30 parts of Herba Violaes, 10 ~ 15 parts of Folium Isatidiss, 3 ~ 6 parts of Radix Gentianaes, 3 ~ 10 parts of Radix Scutellariaes, 3 ~ 10 parts of Fructus Gardeniaes, 6 ~ 12 parts of Fructus Arctiis, 3 ~ 10 parts of Radix Bupleuri, 3 ~ 10 parts of Rhizoma Corydalis, 3 ~ 9 parts of Radix Aconiti Preparatas, 1 ~ 3 part of Scolopendra, 3 ~ 9 parts on Flos Carthami, 3 ~ 10 parts of Olibanums, 10 ~ 15 parts of Semen Plantaginiss.
Further, the parts by weight of said each crude drug are preferably: 10 parts of Flos Loniceraes, 20 parts of Herba Taraxacis, 20 parts of Herba Violaes, 15 parts of Folium Isatidiss, 6 parts of Radix Gentianaes, 10 parts of Radix Scutellariaes, 10 parts of Fructus Gardeniaes, 10 parts of Fructus Arctiis, 6 parts of Radix Bupleuri, 10 parts of Rhizoma Corydalis, 6 parts of Radix Aconiti Preparatas, 1.5 parts of Scolopendras, 9 parts on Flos Carthami, 6 parts of Olibanums, 10 parts of Semen Plantaginiss.
Preferably, Olibanum is an Olibanum (processed).
Process any acceptable clinically preparation by conventional method, such as can be decoct, pill, capsule, granule or concentrated pill.Can choose and add corresponding conventional adjuvant according to the needs of different preparations.
Method for preparing and method for using:
The PD phase: 1. in by weight/volume; Take by weighing Flos Lonicerae 6 ~ 15g, Herba Taraxaci 10 ~ 30g, Herba Violae 15 ~ 30g, Folium Isatidis 10 ~ 15g, Radix Gentianae 3 ~ 6g, Radix Scutellariae 3 ~ 10g, Fructus Gardeniae 3 ~ 10g, Fructus Arctii 6 ~ 12g, Radix Bupleuri 3 ~ 10g, Rhizoma Corydalis 3 ~ 10g, Radix Aconiti Preparata 3 ~ 9g, Scolopendra 1 ~ 3g, Flos Carthami 3 ~ 9g, Olibanum 3 ~ 10g, Semen Plantaginis 10 ~ 15g; Then this 15 flavor crude drug is put into marmite; First fries in shallow oil and adds water 600ml and soaked 30 minutes; After boiling with high heat earlier, used the about 350ml of taking liquid again instead 30 minutes at a simmer; Second fries in shallow oil and adds water 500ml, uses the about 350ml of taking liquid again instead 25 minutes at a simmer after boiling with high heat earlier; Two boil medicine liquid mix after clothes at twice, early, evening each clothes once, decoction being taken warmly.Or, 2. utilize prior art to process granule the present invention's 15 flavor crude drug, divide the bag of packing into, every bag of 10g obeys 1 bag at every turn, obeys warm boiled water every day three times.
The stable disease phase: by weight ratio; Take by weighing Flos Lonicerae 6 ~ 15g, Herba Taraxaci 10 ~ 30g, Herba Violae 15 ~ 30g, Folium Isatidis 10 ~ 15g, Radix Gentianae 3 ~ 6g, Radix Scutellariae 3 ~ 10g, Fructus Gardeniae 3 ~ 10g, Fructus Arctii 6 ~ 12g, Radix Bupleuri 3 ~ 10g, Rhizoma Corydalis 3 ~ 10g, Radix Aconiti Preparata 3 ~ 9g, Scolopendra 1 ~ 3g, Flos Carthami 3 ~ 9g, Olibanum 3 ~ 10g, Semen Plantaginis 10 ~ 15g; Then this 15 flavor Chinese medicine is pulverized the back and cross 120 mesh sieves; After processing superfine medicated powder: 1. medicated powder and honey are processed honeyed pill by the 1:1.5 mass ratio, every ball 3g obeys 6g at every turn; Obey warm boiled water every day three times; Or, 2. with the medicated powder Capsules of packing into, every 0.3g, obey 6, every day three times, warm boiled water at every turn; Or, 3. utilize prior art to process concentrated pill the present invention's 15 flavor crude drug, obey 6g at every turn, obey warm boiled water every day three times.
Pharmacology of the present invention:
Flos Lonicerae: sweet and slightly bitter taste is cold in nature, returns lung, the heart, stomach warp, has the effect of heat-clearing and toxic substances removing, dispelling wind and heat pathogens.These article are sweet cold, both heat-clearing and toxic substances removing, and tool is gently declared the property of evacuation again, heresy that can the warm epidemic disease poison of removing summer-heat, the carbuncle of loosing is again subsided a swelling, for controlling the key medicine of all carbuncle furuncle YANG syndromes.Can be used for furuncle swelling toxin, red and swollen heat pain, hard dark person, be equal to effect better with Herba Taraxaci, Herba Violae.
Herba Taraxaci: bitter but sweet flavor is cold in nature, returns liver, stomach, lung meridian, has effects such as heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, eliminating damp-heat.These article are bitter to be let out to fall, cold with heat clearing away.Can removing summer-heat burning hot poison is evil, can go into liver again and fall and let out stagnant gas, so be the good merchantable brand of heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.Sore and toxic due to all hyperactivity of toxic heat is no matter abscess of internal organ or external carbuncle all can be controlled it.Get the merit that it controls skin carbuncle furunculosis.Essentials of Matea Medica: " specially controlling acute mastitis, furunculosis, also is treating stranguria quality goods ".
Herba Violae: the bitter in the mouth suffering is cold in nature, and GUIXIN, Liver Channel have the effect of heat-clearing and toxic substances removing, removing heat from blood detumescence.These article hardship is let out hot loosing, cold can heat clearing away, go into the conscience blood system, thus can heat-clearing and toxic substances removing, the removing heat from blood eliminating carbuncle, malicious for the treatment dominance of heat in the interior furuncle furuncle that heat in blood stops up due to stagnating of holding concurrently, the common drug of red and swollen heat pain is its speciality to control furunculosis especially.With controlling carbuncle, furuncle, erysipelas etc., it is for oral administration singly to smash juice with bright article.Compendium of Material Medica: " controlling all carbuncle carbuncle on the back, furuncle scrofula, innominate toxic swelling, malignant boil ".
Folium Isatidis: bitter in the mouth property Great Cold return lung, stomach, the heart, Liver Channel, have the effect of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.This taste bitterness Great Cold, its power analgesic and blood cooling and ecchymoses removing is strong especially, and going into edema caused by disorder of QI can clearing away heat-fire, and going into blood system can blood cooling and ecchymoses removing, goes into nutrient blood so can be used for controlling heat, intense heat in both QI and blood systems, diseases such as maculae caused by violent heat pathogen; Other can be used for each stage and the affection due to external wind and heat disease of epidemic febrile disease; With controlling disease such as erysipelas carbuncle, available bright article are mashed external application.Compendium of Material Medica: " main pyrotoxic dysentery, jaundice, sore throat, erysipelas ".
Radix Gentianae: bitter in the mouth is cold in nature, returns liver, gallbladder, urinary bladder channel, has the effect of heat clearing and damp drying, eliminating fire and detoxication.These article also are the dry medicine of bitter cold property, and the merit of good heat clearing and damp drying is also arranged.Both the liver heat removing gallbladder was damp and hot, again eliminating pathogen in the liver gallbladder excess-fire.The hypochondriac pain of containing in the available treating the liver fire etc.Because of Liver Channel cloth two sides of body, and mostly the predilection site of herpes zoster is breast side of body portion." medication on the analogy of natural things ": " move back the Liver Channel pathogenic heat, it is swollen to remove damp-heat in lower-JIAO, rushes down the bladder fire ".
Radix Scutellariae: bitter in the mouth is cold in nature, returns lung, stomach, gallbladder, large intestine channel, has the effect of heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis.These article bitter cold and dry has stronger heat clearing and damp drying, the power of eliminating fire and detoxication, and damp-heat in upper-JIAO among the You Shanqing is controlled the flourishing diseases such as sore and toxic of fire-toxin.
Fructus Gardeniae: bitter in the mouth is cold in nature, and GUIXIN, liver, lung, stomach, tri-jiao channel have the effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, reducing swelling and alleviating pain.The property that these article bitter cold is fallen clearly is stronger, can rush down edema caused by disorder of QI excess-heat, the logical fire that rushes down three warmers clearly, heat-clearing and toxic substances removing, effects such as removing damp-heat from the liver and the gallbladder.Cure mainly the diseases such as red and swollen heat pain of pyretic toxicity carbuncle sore.
Fructus Arctii: the acrid in the mouth bitterness is cold, attaches to the lung and stomach meridians, and has dispelling wind pathogens, rash sore-throat relieving, the detoxifcation effect such as swollen of loosing.This taste is arduous cold in nature, the property of falling is clearly arranged in rising among floating again, the wind heat of loosing outward, in separate pyretic toxicity, heat-clearing and toxic substances removing is arranged, the effect of the sore-throat relieving of subsiding a swelling.So with controlling pyretic toxicity cards such as carbuncle sore tumefacting virus, erysipelas.Tool is let out clearly and is loose again, can dispelling wind and heat pathogens, the expelling heat from the exterior pyretic toxicity and impel the herpes poison evil pass through send out in outside.Do not pass through or answer thoroughly diseases such as latent with controlling herpes.
Radix Bupleuri: the hot cold nature of bitter in the mouth, return liver, gallbladder meridian, have evacuate bring down a fever, the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang.The hot hardship of loosing of these article is let out, is slightly cold and brings down a fever, and is good at the eliminating evil heresy of inducing sweat and bringing down a fever and evacuating few positive half exterior and half interior.For controlling evil key medicine in shaoyang channel, and the kind bar of its property reaches irritability, dispersing the stagnated live-QI to relieve the stagnation of QI, thus the pain in chest and hypochondrium of the treating the liver stagnation of QI due to stagnant, no matter internal injury stagnation of liver-QI, wound traumatic injury all can be used.
Rhizoma Corydalis: acrid in the mouth bitterness temperature, return liver, spleen, heart channel, have invigorate blood circulation, the effect of circulation of qi promoting, pain relieving.The hot temperature of loosing of these article is logical, the stagnation of QI in the ability promoting the circulation of blood, and stasis in the gas so specially control all up and down all over the body pains, is the pain relieving key medicine.Which kind of pain disease no matter, but all compatibility is used, and especially all pains of internal organs is good at the most, can be used for the strongly fragrant stagnation of QI of treating the liver, diseases such as distending pain over the hypochondrium.
Radix Aconiti: acrid in the mouth bitterness heat, very toxic, GUIXIN, liver,kidney,spleen warp have the effect of expelling wind and removing dampness, dispersing cold for relieving pain.These article have stronger analgesic effect, are used to control wound stasis of blood pain and herpetic causalgia, are to get its narcotic analgesic effect.
Scolopendra: acrid in the mouth is warm in nature, and is poisonous, returns Liver Channel, has the effect of endogenous wind stopping relieving convulsion, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.The hot row temperature of these article is logical, extending from the interior to the exterior.The ability dispersing pathogen accumulation is a surgery medicine commonly used.Invade in all pyretic toxicity or furuncle swelling toxin, the scrofula sucutaneous nodule of phlegm-damp due to condensing, oral administration and externally all can be got effect.The merit of tool removing obstruction in the collateral to relieve pain in addition is stronger with Rhizoma Corydalis, Radix Aconiti compatibility analgesic effect.
Flos Carthami: acrid in the mouth is warm in nature, and GUIXIN, Liver Channel have the effect of promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.The hot temperature of loosing of these article is logical, specially goes into blood system, ability blood circulation promoting and blood stasis dispelling Xiao wei, and the effect of unobstructed passages through which vital energy circulates, reducing swelling and alleviating pain is the key medicine of promoting blood circulation to restore menstrual flow pain relieving.Other has the merit of removing pathogenic heat from blood and toxic substance from the body.Be used for diseases such as the macule color is dark, heat stagnation blood stasis, get the invigorate blood circulation merit of dissipating rashes of its these article.
Olibanum: acrid in the mouth bitterness temperature, return liver, the heart, spleen channel, have the effect of blood-activating and qi-promoting pain relieving, detumescence and promoting granulation.The hot temperature of loosing of these article is logical, and internal energy a surname lead to internal organs, and external enwergy reaches meridians thoroughly, can blood circulation promoting and blood stasis dispelling, can manage it the gas that stagnates that looses again, and the merit of pain relieving is more outstanding, can " fixed all through bitterly " " pearl sac ".The hot perfume (or spice) of the tool property of walking to scurry in addition can promoting blood circulation and detumescence, again can promoting tissue regeneration and ulcer healing, the kind pain of controlling stagnation of QI and blood and sore swollen toxin from the beginning of or the skin infection diabrosis, do not close up for a long time at disease." Mingyi Bielu ": " it is swollen to treat the edema due to wind pathogen poison, removes bad odor, treats the urticaria poison of itching ".
Semen Plantaginis: sweet in the mouth is cold in nature, returns kidney, liver, lung meridian, has the effect of inducing diuresis for treating stranguria syndrome, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat from the lung and dissipating phlegm.These article are sweet cold sliding sharp, and kind tonneau water channel can eliminating dampness and diuresis, and removing heat from the liver and making eye bright is used for treating the liver through damp and hot, gets its clearing away heat-damp and promoting diuresis, make damp and hotly to discharge from water channel.
More than all medicine compatibilities, play the effect of letting out liver-fire, detoxification and promoting urination, promoting blood circulation to remove obstruction in the collateral, regulating QI to relieve pain clearly altogether.Be used for treatment because of depression of liver-QI, for a long time and fire-transformation, it is long-pending that the Liver Channel fire-toxin accumulates, excessive skin and the herpes of life; Or impression poison is evil, and damp and hot poison accumulates, and causes coagulation of QI-blood, meridians blocking barrier, so that sharp ache such as fire burn, and with the passing of time could disappear.Its skin erythema, blisters or herpes mound, numerous such as beads, arranged in a strip along the side of the peripheral nerve distribution area appears, local irritation or with Xing nuclear enlargement.Its position is mainly in breast side of body portion, also is found in face or abdominal part etc.
Herpes zoster is that herpesvirus is invaded and neurally in dorsal root spinal ganglion neuron or cranial nerve sensory nerve ganglion neuron, to be caused the pain as burning like fire with hiding.But up to now, still there is not specific antiviral Western medicine.So use the Western medicine symptomatic treatment merely, effect is not remarkable, and makes patient Yi Liu pain sequela, suffers untold misery.The present composition has the effect of letting out liver-fire, detoxification and promoting urination, promoting blood circulation to remove obstruction in the collateral, regulating QI to relieve pain clearly.The malicious pain relieving of can effectively detoxifying has avoided leaving over the drawback that pain of a specified duration does not heal again.
The specific embodiment
Below in conjunction with specific embodiment technical scheme of the present invention is done to introduce in detail further, but protection scope of the present invention is not limited thereto.
Embodiment 1
Flos Lonicerae 6g, Herba Taraxaci 30g, Herba Violae 15g, Folium Isatidis 12g, Radix Gentianae 3g, Radix Scutellariae 6g, Fructus Gardeniae 7g, Fructus Arctii 12g, Radix Bupleuri 10g, Rhizoma Corydalis 3g, Radix Aconiti Preparata 9g, Scolopendra 3g, Flos Carthami 3g, Olibanum (processed) 10g, Semen Plantaginis 15g.
Method for preparing and method for using:
The PD phase: 1. above-mentioned 15 flavor crude drug are put into marmite, first fries in shallow oil and adds water 600ml and soaked 30 minutes, after boiling with high heat earlier, uses the about 350ml of taking liquid again instead 30 minutes at a simmer; Second fries in shallow oil and adds water 500ml, uses the about 350ml of taking liquid again instead 25 minutes at a simmer after boiling with high heat earlier; Two boil medicine liquid mix after clothes at twice, early, evening each clothes once, decoction being taken warmly.Or, 2. utilize prior art to process granule above-mentioned 15 flavor crude drug, divide the bag of packing into, every bag of 10g obeys 1 bag at every turn, obeys warm boiled water every day three times.
The stable disease phase: above-mentioned 15 flavor Chinese medicines are pulverized the back cross 120 mesh sieves, process superfine medicated powder after: 1. medicated powder and honey are processed honeyed pill by the 1:1.5 mass ratio, every ball 3g obeys 6g, every day at every turn and obeys warm boiled water three times; Or, 2. with the medicated powder Capsules of packing into, every 0.3g, obey 6, every day three times, warm boiled water at every turn; Or, 3. utilize prior art to process concentrated pill the present invention's 15 flavor crude drug, obey 6g at every turn, obey warm boiled water every day three times.
Embodiment 2
Flos Lonicerae 10g, Herba Taraxaci 20g, Herba Violae 20g, Folium Isatidis 15g, Radix Gentianae 6g, Radix Scutellariae 10g, Fructus Gardeniae 10g, Fructus Arctii 10g, Radix Bupleuri 6g, Rhizoma Corydalis 10g, Radix Aconiti Preparata 6g, Scolopendra 1.5g, Flos Carthami 9g, Olibanum (processed) 6g, Semen Plantaginis 10g.
Method for preparing and method for using are with embodiment 1.
Embodiment 3
Flos Lonicerae 15g, Herba Taraxaci 10g, Herba Violae 30g, Folium Isatidis 10g, Radix Gentianae 4.5g, Radix Scutellariae 3g, Fructus Gardeniae 3g, Fructus Arctii 6g, Radix Bupleuri 3g, Rhizoma Corydalis 7g, Radix Aconiti Preparata 3g, Scolopendra 1g, Flos Carthami 6g, Olibanum (processed) 3g, Semen Plantaginis 13g.
Method for preparing and method for using are with embodiment 1.
Clinical trial
1.1 physical data
From year August in January, 2005 to 2011, accept herpes zoster patient 102 examples for medical treatment.All case is all made a definite diagnosis through multiple inspections such as health check-up and the inspections of laboratory herpes scraping blade, and does not have severe cardiac, liver, the bad person of renal function.Be divided into treatment at random and organize 51 examples, wherein male 29 examples, women 22 examples, 21 ~ 79 years old age, 52 years old mean age; Matched group 51 examples, wherein male 30 examples, women 21 examples, 20 ~ 80 years old age, 53 years old mean age.Two groups are not all had significant difference (P>0.05) at aspects such as sex, age, the state of an illness, have comparability, see table 1 for details.
Figure 521903DEST_PATH_IMAGE001
1.2 diagnostic criteria
1. good being sent out season in spring and autumn; 2. being banded herpes of arranging, is the integrated crowd's of red grouper pimple or the big tuftlet of Semen Glycines vesicle, and that bleb liquid is is clear and bright, muddy, blood blister or necrosis; 3. follow the peripheral nerve pain of herpes areal area; 4. laboratory carries out inspections such as herpes scraping blade.
1.3 Therapeutic Method
Matched group: adopt the routine of western medicine treatment: antiviral is used acyclovir, and trophic nerve is used vitamin B 1, B 12, other symptomatic treatment.
Treatment group: on the basis of matched group, add the embodiment of the invention 2 prescriptions and preparation method thereof, method for using with the routine of western medicine treatment.
Two groups treated for 3 weeks respectively after, observe herpes place's skin lesion and clinical symptoms and improve situation.
1.4 therapeutic evaluation
Produce effects: patient's herpes disappears, the skin lesion healing, and peripheral nerve pain disappears, and sensation is normal.
Effectively: patient's herpes place skin lesion heals basically, and peripheral nerve has a dull ache or affected part sensation mile abnormality.
Invalid: patient's herpes place's skin lesion and peripheral nerve pain all do not have obvious improvement.
1.5 statistical method
Data are represented with rate, adopt X 2Check is with P<0.05 for difference has statistical significance.
1.6 result
1.6.1 two groups of doing well,improving example numbers in treatment front and back and improvement rate are relatively
The treatment group is treated on the basis with routine of western medicine at matched group and is added Chinese medicine composition of the present invention, and clinical symptoms improvement rate (97.7%) obviously is superior to matched group merely with routine of western medicine treatment back clinical symptoms improvement rate (75.1%), sees table 2 for details.
Figure 344366DEST_PATH_IMAGE002
1.6.2 untoward reaction
It is nauseating that matched group has 5 examples abdominal distention to occur, has 1 example ERY (++) to occur.The treatment group is not seen other untoward reaction.
Model case
Case 1
Yang, the man, 78 years old, the cadre lived in East St people from village, area just outside a city gate town at present, on February 27th, 2008, came the inventor to locate to go to a doctor with " herpes zoster ".Patient's one all causes are suffered from cold and the left side migraine occurred, once in county people's hospital treatment (medication the is not quite clear) commentaries on classics of not getting better.Can not fall asleep because of sharp ache last night, so transfer the inventor place.Prevalent: left brow lateral facial herpes appear bright red, cluster integrated ribbon, severe pain, accompanied by the left submandibular Xing nuclear enlargement, diameter of about 0.8cm, pain, upset, restless, red tongue, yellow coating, pulse string number.Routine: WBC 6.0 * 10 has a blood test 9/ L, RBC 4.3 * 10 12/ L, L:46%, T:37.5 ℃, R:20 time/minute, P:82 time/minute, BP:150/90mmHg.
Dialectical Analyses: old, blood-deficiency leading to hyperactivity of the liver, the evil poison of multiple sense, so that damp and hot fire-toxin accumulates and scurries women's head-ornaments on long-pending, the folder ailment said due to cold or exposure and send out and be herpes, and damp and hot poison is contained, and stagnation of QI-blood, so that sharp ache are vexed not peaceful.Red tongue, yellow fur, wiry and frequent pulse are the disease of Sheng in the liver-fire.
Diagnosis: (herpes zoster) herpes zoster: stagnated heat of liver channel type.
The rule of treatment: let out liver-fire clearly, detoxification and promoting urination, removing obstruction in the collateral to relieve pain.
Side's medicine: the embodiment of the invention 2 prescriptions and preparation method thereof, method for using.
Western medicine: antiviral is used acyclovir, and trophic nerve is used vitamin B 1, B 12, other symptomatic treatment.
After two weeks after treatment, patients with facial herpes waning healing, pain, sleep well, left mandibular swelling Xing nuclear disappeared and more.Advise and continue to take 2 weeks of honeyed pill that the embodiment of the invention 2 prescriptions are processed.After repeatedly follow up a case by regular visits to, there is not recurrence.
Case 2
Xiao, the woman, 52 years old, the workman lived eight li streets of Puyang at present, on July 19th, 2011, came the inventor to locate to go to a doctor with " herpes zoster ".The patient coerces rib and back pain because of feelings will on the left of freely not occurring before 2 weeks, occur herpes then, bunch integrated.Once infused and treatment by Chinese herbs to Puyang institute of traditional Chinese medicine, effect is not good enough.Left side side of body portion sharp ache is gone into Night Watch very, so change the inventor place over to.Disease is seen: be bunch integrated herpes under oxter, left side and the breast, color is scarlet, scorching hot twinge, and the bitter taste xerostomia can not be fallen asleep, red tongue, yellow and thin fur, wiry and frequent pulse.Routine blood test shows: WBC 7.0 * 10 9/ L, RBC 4.2 * 10 12/ L, L:47%, T:37.3 ℃, R:18 time/minute, P:80 time/minute, BP:130/75mmHg.
Dialectical Analyses: because depression of liver-QI, Liver Channel fire-toxin of a specified duration accumulates and amasss in skin, so coerce rib and herpes appears in the back, bunch integrated.Warm poison accumulates, stagnation of QI-blood, so pain is acute.Go into Yu Yin night, so hypnalgia very, flaming up of liver-fire is so see the bitter taste xerostomia.Red tongue, yellow and thin fur, wiry and frequent pulse are resembling of stagnated heat of liver channel.
Diagnosis: (herpes zoster) herpes zoster: stagnated heat of liver channel type.
The rule of treatment: let out liver-fire clearly, detoxifcation pain relieving etc.
Side's medicine: the embodiment of the invention 1 prescription and preparation method thereof, method for using.
Western medicine: antiviral is used acyclovir, and trophic nerve is used vitamin B 1, B 12, other symptomatic treatment.
After 2 weeks of treatment, the affected part herpes disappears gradually and heals, and pain disappears, and bitter taste in the mouth and dry throat is eliminated.Advise and continue to take 2 weeks of honeyed pill that the embodiment of the invention 1 prescription processes in case leave over neuralgia.After repeatedly follow up a case by regular visits to, there is not recurrence.
Case 3
Yao so-and-so, the woman, 56 years old, the peasant was Gu Jin building township Wu Jia people from village, on JIUYUE 18th, 2005, came the inventor to locate to go to a doctor with " herpes zoster ".The patient is before January, and because of occurring right side stomachache after suffering from cold, the cerise herpes appears in right abdominal part after 3 days, bunch integrated several pieces, sharp ache.Once the treatment in the locality, the powder that uses medicine for external application, curative effect is not good enough.Merge necrosis because of infection is festered herpes, make pain more violent.Once cured many places, and symptom is difficult to control, so change the inventor place over to.Disease is seen: right lower abdomen many places ulcer, and than large tracts of land 5cm * 7cm, the surface is the purulence slough, has an intense pain, feel restless, dark tongue quality, tongue is white, stringy and thready pulse.Routine blood test shows: WBC 12 * 10 9/ L, RBC 3.7 * 10 12/ L, L:56%, T:37.8 ℃, R:18 time/minute, P:78 time/minute, BP:135/70mmHg.
Dialectical Analyses: because depression of liver-QI, the evil poison of multiple sense, for a long time and fire-transformation is recklessly acted, intenseness of heat then meat is rotten, and so the folder downward flow of dampness festers in flakes see the abdominal part many places, accumulates in the damp and hot fire-toxin, causes stagnation of QI-blood, and meridians blocking barrier, so that sharp ache are felt restless, and the course of disease is delayed.Dark tongue quality, tongue is white, and stringy and thready pulse is the disease of stagnation of QI-blood.
Diagnosis: (herpes zoster) herpes zoster: stagnation of QI-blood, accumulate type in the fire-toxin.
The rule of treatment: let out liver-fire clearly, detoxification and promoting urination, promoting blood circulation to remove obstruction in the collateral, regulating QI to relieve pain.
Side's medicine: the embodiment of the invention 3 prescriptions and preparation method thereof, method for using.
Western medicine: antiviral is used acyclovir, and trophic nerve is used vitamin B 1, B 12, other symptomatic treatment.
After 3 weeks of treatment, patient's abdominal part rotten position is all formed a scab, and partly comes off, and pain disappears, and it is ruddy that body of the tongue is changeed, and pulse is as usual, and it is normal that body temperature and routine blood test all recover.Advise and continue to take made 2 weeks of honeyed pill of the embodiment of the invention 3 prescriptions, the recovery from illness that all comes off of abdominal part skin lesion place crust.So far there is not recurrence through repeatedly following up a case by regular visits to.

Claims (5)

1. a Chinese medicine composition of treating herpes zoster is characterized in that being processed by each crude drug of following portions by weight: 6 ~ 15 parts of Flos Loniceraes, 10 ~ 30 parts of Herba Taraxacis, 15 ~ 30 parts of Herba Violaes, 10 ~ 15 parts of Folium Isatidiss, 3 ~ 6 parts of Radix Gentianaes, 3 ~ 10 parts of Radix Scutellariaes, 3 ~ 10 parts of Fructus Gardeniaes, 6 ~ 12 parts of Fructus Arctiis, 3 ~ 10 parts of Radix Bupleuri, 3 ~ 10 parts of Rhizoma Corydalis, 3 ~ 9 parts of Radix Aconiti Preparatas, 1 ~ 3 part of Scolopendra, 3 ~ 9 parts on Flos Carthami, 3 ~ 10 parts of Olibanums, 10 ~ 15 parts of Semen Plantaginiss.
2. the Chinese medicine composition of treatment herpes zoster as claimed in claim 1 is characterized in that being processed by each crude drug of following portions by weight: 10 parts of Flos Loniceraes, 20 parts of Herba Taraxacis, 20 parts of Herba Violaes, 15 parts of Folium Isatidiss, 6 parts of Radix Gentianaes, 10 parts of Radix Scutellariaes, 10 parts of Fructus Gardeniaes, 10 parts of Fructus Arctiis, 6 parts of Radix Bupleuri, 10 parts of Rhizoma Corydalis, 6 parts of Radix Aconiti Preparatas, 1.5 parts of Scolopendras, 9 parts on Flos Carthami, 6 parts of Olibanums, 10 parts of Semen Plantaginiss.
3. according to claim 1 or claim 2 the Chinese medicine composition of treatment herpes zoster, it is characterized in that: Olibanum is an Olibanum (processed).
4. according to claim 1 or claim 2 the Chinese medicine composition of treatment herpes zoster is characterized in that: process any acceptable clinically preparation by conventional method.
5. the Chinese medicine composition of treatment herpes zoster as claimed in claim 4 is characterized in that: said preparation is decoct, pill, capsule, granule or concentrated pill.
CN2011103306547A 2011-10-27 2011-10-27 Traditional Chinese medicine combination for treating herpes zoster Expired - Fee Related CN102357155B (en)

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CN103656361A (en) * 2013-12-10 2014-03-26 张朝兰 Medicine used for treating herpes zoster, and preparation method thereof
CN103784876A (en) * 2014-01-23 2014-05-14 陈天丽 Traditional Chinese medicine formula for treating herpes zoster and preparation method thereof
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CN102716335A (en) * 2012-06-01 2012-10-10 蒋金洲 External Chinese medicinal composition for treating herpes zoster
CN103656361A (en) * 2013-12-10 2014-03-26 张朝兰 Medicine used for treating herpes zoster, and preparation method thereof
CN103656361B (en) * 2013-12-10 2015-06-03 张朝兰 Medicine used for treating herpes zoster, and preparation method thereof
CN103784876A (en) * 2014-01-23 2014-05-14 陈天丽 Traditional Chinese medicine formula for treating herpes zoster and preparation method thereof
CN103784876B (en) * 2014-01-23 2016-06-29 陈天丽 A kind of Chinese medicine formula treating herpes zoster and preparation method thereof
CN106236970A (en) * 2016-08-29 2016-12-21 长沙佰顺生物科技有限公司 A kind of Chinese medicine composition treating Fel Serpentis skin ulcer
CN109432316A (en) * 2018-12-11 2019-03-08 浙江公望堂生物科技有限公司 For traditional Chinese medicine composition for herpes and preparation method thereof

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