CN102356877A - CBP calcium supplement electuary - Google Patents
CBP calcium supplement electuary Download PDFInfo
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- CN102356877A CN102356877A CN2011103116400A CN201110311640A CN102356877A CN 102356877 A CN102356877 A CN 102356877A CN 2011103116400 A CN2011103116400 A CN 2011103116400A CN 201110311640 A CN201110311640 A CN 201110311640A CN 102356877 A CN102356877 A CN 102356877A
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Abstract
The invention relates to the technical field of calcium supplement health products, and specially, relates to CBP calcium supplement electuary. The CBP calcium supplement electuary comprises: by weight, 14 to 18 parts of milk calcium, 1 to 2 parts of colostrum basic protein, 0.5 to 1 part of casein phosphoeptide, 0.5 to 0.7 parts of isoflavone, 0.00001 to 0.00002 parts of vitamin D, and 0.00001 to 0.00002 parts of vitamin K. Compared with the prior art, the CBP calcium supplement electuary contains isoflavone so that after the CBP calcium supplement electuary enters into a human body, isoflavone can combine with estrogen acceptors of osteocytes, and thus through the CBP calcium supplement electuary, sclerotin loss is reduced; calcium absorption capacities of human bodies are improved; bone mineral density is increased; osteoporosis can be prevented and improved; and real and good calcium supplement effects are obtained.
Description
Technical field
The present invention relates to the technical field of calcium supplement health care product, particularly a kind of CBP supports the calcium electuary.
Background technology
Osteoporosis is meant the bone tissue minimizing and causes bone crisp and frangible, is prone to fracture.Osteoporosis is a geriatric disease, is common in women and old man (because hormone variation or calcium and vitamin d insufficiency) after climacteric.The middle and aged women osteoporosis incidence of disease is high more a lot of than the male sex, and main cause is an ovarian function decline back decrease in estrogen, bone metabolism appearance of negative balance, and the bone amount reduces.The bone that the women was utilized after 40 years old is more than their fertile bone, and annual 5% of its bone that runs off of menelipsis women, this process reduces along with estrogen level and quickens.
After women's menopause, the decline of body inner estrogen level can cause that a series of is the menopause symptom of characteristic with the Tidal fever with perspiration.It is old and feeble natural process that sclerotin continues to lose, and women's back estrogen level that enters into the climacteric period descends fast, thereby quickens bone loss.The epidemiology survey result shows, has 25% climacteric women that the Tidal fever with perspiration symptom is arranged in Japan, but in the North America this women then up to 85%.WHO compares the Japan and the American-European menopause women osteoporosis incidence of disease, finds that Japanese osteoporosis and the marrow bone fracture incidence of disease is starkly lower than states such as America and Europe.Over nearly 10 years, the various countries scholar carries out a large amount of clinical testings and zoopery attempts to find the relation between soybean intake and climacteric women osteoporosis and the hectic fever incidence.The result shows that soybean protein has significant improvement effect to menopause women hectic fever symptom.At present, seldom for the clinical trial of isoflavones and osteoporosis relation.Recently Potter to menopause after the hypercholesterolemia women carried out a meals intervention experiment.The result finds that experimenter's BMC and the bone density of taking in the 90mg isoflavones every day have increased by 2%, have compared significant difference with control group.Discover that isoflavones can combine with the ERs on the osteocyte, reduce bone-loss, increase the absorption of body simultaneously, increase bone density calcium.
And at present on the market a lot of calcium-supplementing preparations to middle aged and aged women mostly exist and only pay attention to additional calcium, and have ignored additional isoflavones, cause the unfavorable defective of effect of replenishing the calcium.
Summary of the invention
The object of the invention is to provide a kind of CBP to support the calcium electuary; Mostly there is the additional calcium of only emphasis in existing a lot of calcium-supplementing preparations to middle aged and aged women in the prior art to solve; And ignored additional isoflavones, the technical matters of the unfavorable defective of effect that causes replenishing the calcium.
The object of the invention realizes through following technical scheme:
A kind of CBP supports the calcium electuary, and it contains the following compositions in weight portion:
Milk calcium: 14-18 part,
The colostrum basic protein: 1-2 part,
CPP: 0.5-1 part,
Isoflavones: 0.5-0.7 part,
Vitamin D: 0.00001-0.00002 part,
Vitamin K: 0.00001-0.00002 part.
Preferably, it contains the following compositions in weight portion:
Milk calcium: 15 parts,
The colostrum basic protein: 1 part,
CPP: 0.6 part,
Isoflavones: 0.5 part,
Vitamin D: 0.00001 part,
Vitamin K: 0.00001 part.
Compared with prior art, CBP of the present invention supports in the calcium electuary and contains isoflavones, make that calcium tonic gets into human body after; Isoflavones can combine with the ERs on the osteocyte, reduces bone-loss, increases the absorption of body to calcium simultaneously; Increase bone density; Can prevent and improve osteoporosis, really play the effect of replenishing the calcium, advantages of good calcium supplying effect.
The specific embodiment
Below in conjunction with embodiment, specify the present invention.Following examples only are used to explain the present invention, are not used for limiting scope of the present invention.
CBP of the present invention supports the calcium electuary, and it contains the following compositions in weight portion:
Milk calcium: 14-18 part,
The colostrum basic protein: 1-2 part,
CPP: 0.5-1 part,
Isoflavones: 0.5-0.7 part,
Vitamin D: 0.00001-0.00002 part,
Vitamin K: 0.00001-0.00002 part.
Below be a most preferred embodiment of the present invention, it contains the following compositions in weight portion:
Milk calcium: 15 parts,
The colostrum basic protein: 1 part,
CPP: 0.6 part,
Isoflavones: 0.5 part,
Vitamin D: 0.00001 part,
Vitamin K: 0.00001 part.
After fully mixing in the pulvis adding blender of said ratio requirement with milk calcium (newborn mineral salt, calcic 24-28%), colostrum basic protein, CPP, isoflavones, vitamin D and vitamin K, can make finished product by quantitative package.
Method for using: these article are pulvis, ante cibum one after each meal all can, get finished product be dissolved in right amount stir in an amount of warm boiling water or the milk promptly drinkable.
Beneficial effect is analyzed:
One, the beneficial effect analysis of milk calcium
Milk calcium also is whey calcium, is from milk, extract calcareous, the combination of the one type of mineral salt that obtains after process dehydration, degreasing, the dry spraying; Its calcic 24-28%; It is of high nutritive value, and composition comprises calcium citrate, calcium phosphate, ionized calcium, also contains rich nutrient contents such as zinc, phosphorus, protein, immunoglobulin (Ig), growth factor, lactoferrin; In all calcium classes, cow's milk calcium is absorbed by the body the most easily.Calcium in the cow's milk calcium powder, phosphorus ratio are coordinated rationally, and its naturally occurring vitamin D, CPP natural nutrition compositions such as (CPP) all are the factors that best help calcium absorbs.
It is the separable ionic condition that appears that milk calcium does not need too many hydrochloric acid in gastric juice to participate in human body, and then is directly absorbed by human body, regulates the blood calcium balance rapidly, builds up health.Milk calcium be all of generally acknowledging calcareous in " bioavailability " the highest food-grade calcium complement agent because also have an amount of albumen and reasonably calcium, phosphorus ratio 2 ︰ 1 in the milk calcium; Simultaneously, because have no chemical composition and technology in its production process, intestines and stomach had no burden.
Milk calcium is the high lactoprotein calcium of pure natural active that directly from milk, extracts; Owing to contain abundant lactose and albumen in the cow's milk; So its absorptivity is much higher than other food and common calcium, its absorptivity is calcium carbonate and calcium gluconae 2.5 times up to 62%-70%; Being 1.75 times of calcium lactate, is 5.5 times of shellfish calcium.
Two, the beneficial effect analysis of colostrum basic protein
Discover that the metabolism of bone may further comprise the steps:
(1) blood is transported to osteoclast on the bone;
(2) osteoclast is attached on the bone then, and osteoclast disengages acidic materials and ferment dissolving and destroys sclerotin;
(3) after step (2) work was accomplished, osteoclast just can disappear, and osteoblast occurs;
(4) osteoblast is made ossein and is enclosed one deck stickum, and afterwards, calcareous the investing on the ossein in the blood forms healthy bone.
Colostrum basic protein (CBP) is the low-molecular-weight activated protein of from colostrum, separating, and can carry out bidirectional modulation to bone cells, and CBP can suppress the osteoclast activity on the one hand; Can promote osteoblast quantity to increase and liveness on the other hand; Be maintained in osteocyte and osteoclast dynamic benign balance, let human body active absorption calcium, pin calcium; Thereby enhance bone density and length promote bone health.
CBP promotes the concrete manifestation of bone health to comprise:
1) is increased in the osteoblast quantity of bone;
2) stimulate osteoblast to make ossein;
3) help and absorb calcareously, prevent calcium loss;
4) suppress the osteoclast activity;
5) balance between adjusting osteoclast and the osteoblast is regulated bone metabolism.
Three, the beneficial effect analysis of CPP
(Casein phosphopeptides CPP) is bovine casein (α S1, α S2, beta-casein and κ-casein) through hydrolysis, separation and purification and obtains one type and be rich in the phosphoserine biologically active peptide CPP.
1) CPP promotes the absorption of body to calcium
CPP can improve the absorption of body to calcium, phosphorus, make the level of plasma calcium and the blood plasma phosphorus degree that reaches capacity, but synthetic calbindin in the inductor is promoted calcium and absorbed.
The additive that tradition promotes calcium to absorb is a vitamin D; Vitamin D can promote the active transport of the saturable calcium of upper part of small intestine to absorb; But the effect of vitamin D receives the influence of age and calcium intake, and excessive vitamin D can cause certain harm to the kidney and the bone of human body.CPP is to the not passive diffusion absorption of saturable of small intestine bottom, and this absorption does not receive the influence of age and calcium intake variation, and the passive diffusion absorption of calcium absorbs much larger than active transport.And research shows that the dosage of CPP can not produce bad reaction to the health of human body.
2) CPP promotes enteron aisle to the absorption of mineral elements such as iron, zinc, selenium and the enhancing body bioavailability to calcium, iron, zinc, selenium etc.
3) CPP promotes the utilization of tooth to calcium
CPP can be combined in the calcium ion in the food carious tooth place, alleviate enamel go mineralize.Because after the phosphoserine of the CPP bunch combination calcium, be positioned at tooth moth position with amorphous form, the calcium salt of phosphoserine provides Ca freely
2+And PO
4 3-Buffer solution, thus erosion of tooth erosion bacterium and the demineralization phenomenon that causes prevented effectively.
Four, the beneficial effect analysis of isoflavones
Isoflavones is a kind of in the flavone compound, mainly is present in the legume, and isoflavones is the one type of secondary metabolite that forms in the soybeans they grow.Owing to be from plant, to extract, with estrogen analog structure is arranged, so isoflavones is claimed phytoestrogen again.Isoflavones is from the refining bioactivator that forms of non-transgenic soybean, is a kind of active natural nutrition factor of multiple important physiological that has, and is pure natural plants estrogen, is absorbed by the body easily, can supplement the nutrients rapidly.
1) isoflavones can prevent, improve osteoporosis.
The middle and aged women osteoporosis incidence of disease is high, and main cause is an ovarian function decline back decrease in estrogen, bone metabolism appearance of negative balance, and the bone amount reduces.Isoflavones can combine with the ERs on the osteocyte, reduces bone-loss, increases the absorption of body to calcium simultaneously, increases bone density, thereby prevents, improves osteoporosis.
2) but the isoflavones Breast Cancer Prevention.
Taking estrogen for a long time separately can make breast cancer, carcinoma of endometrium incidence increase by 5 to 7 times.The isoflavones structure of matter is similar with female hormone, so can be incorporated into the female receptor of cell surface, activates other anticancer disease mechanism simultaneously, has reduced the danger of women because of estrogen high level trouble carcinoma of endometrium, breast cancer.The dual regulation of isoflavones can reduce estrogen active, reduces the women because of the high danger that suffers from breast cancer of estrogen level.That is, when human body inner estrogen level was low, isoflavones occupied ERs, and the weak estrogen effect of performance shows the effect that improves estrogen level; When human body inner estrogen level was high, isoflavones occupied acceptor site with " competition " mode, the weak estrogen effect of same performance, but because its activity is merely 2% of body inner estrogen, so, show the effect that reduces body inner estrogen level.
3) isoflavones can prevent other cancers.
Soybean prod contains 5 kinds of known anticancer factors, and one of them is phytoestrogen (isoflavones), and this is the distinctive anticancer factor of soybean food.Isoflavones has the obvious treatment effect to colon cancer, lung cancer, prostate cancer and cutaneum carcinoma and leukaemia, and isoflavones also can prevent the generation of oophoroma, colon cancer, cancer of the stomach and prostate cancer.A large amount of researchs find that also it is the cell with normal function that isoflavones can make cancerous cell transformation, simultaneously, can also suppress bad lump structure, prevent the diffusion of lump hyperplasia and cancer cell.
4) but the isoflavones angiocardiopathy preventing.
5) isoflavones can prevent degenerative brain disorder.
6) isoflavones has beauty treatment, function in delaying senility.
Five, the beneficial effect analysis of vitamin D
Vitamin D is the accelerating agent of calcium absorption that product the most often uses of replenishing the calcium, and it can promote calcium at small intestine, or even intracolic absorption.Vitamin D is mainly used in composition and keeps the strong of bone.Only recognize that in present stage vitamin D promotes the absorption of calcium, phosphorus; Can calcium, phosphorus be mobilized from bone again; Make plasma calcium, phosphorus reach normal value, but also synthesize a kind of calbindin in the inductor, it helps calcium and passes through the absorption of the transhipment of intestines wall with enhancement calcium; Impel bone to mineralize, and bring in constant renewal in.It is used to prevent and treat children's rickets and adult's rickets, arthralgia or the like.The people who suffers from osteoporosis can effectively improve the trap of calcium ion through interpolation suitable vitamins D and magnesium.In addition, vitamin D also is used to reduce the probability of colon cancer, breast cancer and prostate cancer, and immune system is also had humidification.
Six, the beneficial effect analysis of vitamin K
Vitamin K is a bone calcium metabolism factor of influence.Osteocyte is mainly synthetic by mineral calcium and protein, discovers recently, and the synthetic bone cell needs vitamin K to participate in, and it can strengthen the affinity of protein to calcium, acts synergistically with vitamin D.Can more effective raising body to the absorption rate of calcium.Vitamin K is participated in the osteocyte metabolism, helps to increase the elderly's bone density especially, thereby can reduce the probability that fracture takes place because of osteoporosis the old man.
Also have data to show, vitamin K can reduce calcium through the excretion of kidney in urine, helps keeping the concentration of human body blood calcium, and calcium balance has positive influences in the body to keeping.
Research finds that also vitamin K also has the bone of participation metabolism, can increase osteoblastic synthesizing, and suppresses the generation of osteoclast, promotes the formation of bone, reduces the catabolism of bone.
CBP of the present invention supports in the calcium electuary and contains isoflavones, makes that isoflavones can combine with the ERs on the osteocyte behind the calcium tonic entering human body; Reduce bone-loss; Increase the absorption of body simultaneously, increase bone density, can prevent and improve osteoporosis calcium; Really play the effect of replenishing the calcium, advantages of good calcium supplying effect.
More than the disclosed several specific embodiments that are merely the application, but the application is not limited thereto, any those skilled in the art can think variation, all should drop in the application's the protection domain.
Claims (2)
1. a CBP supports the calcium electuary, it is characterized in that it contains the following compositions in weight portion:
Milk calcium: 14-18 part,
The colostrum basic protein: 1-2 part,
CPP: 0.5-1 part,
Isoflavones: 0.5-0.7 part,
Vitamin D: 0.00001-0.00002 part,
Vitamin K: 0.00001-0.00002 part.
2. CBP as claimed in claim 1 supports the calcium electuary, it is characterized in that it contains the following compositions in weight portion:
Milk calcium: 15 parts,
The colostrum basic protein: 1 part,
CPP: 0.6 part,
Isoflavones: 0.5 part,
Vitamin D: 0.00001 part,
Vitamin K: 0.00001 part.
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| CN2011103116400A CN102356877A (en) | 2011-10-14 | 2011-10-14 | CBP calcium supplement electuary |
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| CN2011103116400A CN102356877A (en) | 2011-10-14 | 2011-10-14 | CBP calcium supplement electuary |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103599524A (en) * | 2013-11-07 | 2014-02-26 | 苏州冉新生物技术有限公司 | Compound walnut powder solid preparation |
| CN103784939A (en) * | 2012-10-31 | 2014-05-14 | 天狮集团有限公司 | Composition for enhancing bone mineral density |
| CN104432099A (en) * | 2014-12-22 | 2015-03-25 | 威海百合生物技术股份有限公司 | Health food containing vitamin K2 |
| CN104721230A (en) * | 2015-04-13 | 2015-06-24 | 福州乾正药业有限公司 | Composite of milk basic protein and milk mineral, preparation method thereof and application |
| CN104939098A (en) * | 2014-03-26 | 2015-09-30 | 营养屋(成都)生物医药有限公司 | Health food capable of enhancing bone immunity and supplementing and locking calcium and preparation method of health food |
| CN104939089A (en) * | 2015-06-24 | 2015-09-30 | 广州施健生物科技有限公司 | Nutrition composite having function of improving bone mineral density and preparation method and application thereof |
| CN107318927A (en) * | 2017-08-28 | 2017-11-07 | 张志雄 | A kind of biscuit cake |
| CN109527590A (en) * | 2018-12-27 | 2019-03-29 | 安徽康博特保健食品有限公司 | A kind of basic protein protein powder of novel strong bone and preparation method thereof |
| CN109805417A (en) * | 2019-03-01 | 2019-05-28 | 河南九九一生物科技有限公司 | A kind of health food that can increase bone density and its processing method |
| CN111569052A (en) * | 2020-06-30 | 2020-08-25 | 汤臣倍健股份有限公司 | Composition for increasing bone mineral density of climacteric women and health product and application thereof |
| CN112006201A (en) * | 2020-09-03 | 2020-12-01 | 南京润草堂生物科技有限公司 | Calcium-supplementing intestine-clearing sugar-controlling beverage and preparation method thereof |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784939A (en) * | 2012-10-31 | 2014-05-14 | 天狮集团有限公司 | Composition for enhancing bone mineral density |
| CN103599524A (en) * | 2013-11-07 | 2014-02-26 | 苏州冉新生物技术有限公司 | Compound walnut powder solid preparation |
| CN104939098A (en) * | 2014-03-26 | 2015-09-30 | 营养屋(成都)生物医药有限公司 | Health food capable of enhancing bone immunity and supplementing and locking calcium and preparation method of health food |
| CN104432099A (en) * | 2014-12-22 | 2015-03-25 | 威海百合生物技术股份有限公司 | Health food containing vitamin K2 |
| CN104721230A (en) * | 2015-04-13 | 2015-06-24 | 福州乾正药业有限公司 | Composite of milk basic protein and milk mineral, preparation method thereof and application |
| CN104939089A (en) * | 2015-06-24 | 2015-09-30 | 广州施健生物科技有限公司 | Nutrition composite having function of improving bone mineral density and preparation method and application thereof |
| CN107318927A (en) * | 2017-08-28 | 2017-11-07 | 张志雄 | A kind of biscuit cake |
| CN109527590A (en) * | 2018-12-27 | 2019-03-29 | 安徽康博特保健食品有限公司 | A kind of basic protein protein powder of novel strong bone and preparation method thereof |
| CN109805417A (en) * | 2019-03-01 | 2019-05-28 | 河南九九一生物科技有限公司 | A kind of health food that can increase bone density and its processing method |
| CN111569052A (en) * | 2020-06-30 | 2020-08-25 | 汤臣倍健股份有限公司 | Composition for increasing bone mineral density of climacteric women and health product and application thereof |
| CN112006201A (en) * | 2020-09-03 | 2020-12-01 | 南京润草堂生物科技有限公司 | Calcium-supplementing intestine-clearing sugar-controlling beverage and preparation method thereof |
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Application publication date: 20120222 |