CN102349653A - Bone-invigorating collagen calcium granules - Google Patents
Bone-invigorating collagen calcium granules Download PDFInfo
- Publication number
- CN102349653A CN102349653A CN2011103115249A CN201110311524A CN102349653A CN 102349653 A CN102349653 A CN 102349653A CN 2011103115249 A CN2011103115249 A CN 2011103115249A CN 201110311524 A CN201110311524 A CN 201110311524A CN 102349653 A CN102349653 A CN 102349653A
- Authority
- CN
- China
- Prior art keywords
- calcium
- bone
- collagen
- vitamin
- invigorating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to the technical field of calcium-enriching health care products and particularly relates to bone-invigorating collagen calcium granules. The bone-invigorating collagen calcium granules comprise the following ingredients in parts by weight: 14-18 parts of milk calcium, 50-70 parts of hydrolyzed collagen protein, 1-2 parts of colostrum basic protein, 0.00001-0.00002 part of vitamin D and 0.00001-0.0002 part of vitamin K. Compared with the prior art, the bone-invigorating collagen calcium granules contain more collagen protein, so that the collagen protein can enable the calcium to achieve the bone part faster for deposition after a calcium-enriching agent enters into a human body, a calcium-enriching role is really played and the calcium-enriching effect is good.
Description
Technical field
The present invention relates to the technical field of calcium supplement health care product, particularly a kind of strong gelatine protocalcium electuary.
Background technology
Discover that bone is the complicated organism that is made up of bone matrix (collagen and collagenic protein) and bone mineral (calcium hydroxy phosphate and hydroxyl magnesium phosphate).The generation of bone at first is synthetic collagen, and collagenous fibres are intertwined to form the matrix net, and calcium, phosphorus are deposited in the space of collagen stroma net with the calcium hydroxy phosphate form then.There is not collagen just can not be called bone in the bone, just the conglomerate of calcium hydroxy phosphate molecule and particle.
Collagen is the important composition composition in skeleton, the especially cartilaginous tissue.Collagen is just as a net that is full of duck eye in the bone, and it can keep will run off calcareous firmly here.Do not have this net that is full of duck eye,, can be lost in vain yet even if replenished excessive calcium.Generally, inorganic substances such as the calcium in the sclerotin total amount, magnesium, phosphorus only account for a few percent of total amount, and organic substances such as collagen will account for above 80%.Concerning sport people, the continuous sharp wear in joint can form cartilage damage, can not get in a short time and even for good and all recovering.Concerning common people, after 25 years old, the collagen in the body just begins to run off gradually, women especially, because the hormone in vivo imbalance that causes of age, the speed of loss is than the fast several times of the male sex.Therefore the optimum method of keeping joint and bone health is exactly supplement calcium and collagen in time.
Ossein in the osteocyte is the binder of hydroxyapatite, and it and hydroxyapatite have constituted the main body of bone jointly.Calcium in the bone is the mode with the calcium hydroxy phosphate deposition, is that binder is fixed up with the ossein, does not have ossein in the bone, just can not be called bone, is the heap of many calcium hydroxy phosphate molecules and particle; Not having ossein enough and that carrying out eubolism in the bone, will be not hard and unsound.Just because of ossein is the binder of calcium hydroxy phosphate, so ossein is slowly synthetic, is more difficult to get additional, old collagen and constantly degrades, decomposes, and morphs or structural change, even aging.In other words; Binder quality in the bone worse and worse; Quantity is fewer and feweri; Can not effectively whole, the uniform bondings of all calcium hydroxy phosphate molecules be got up and calcium hydroxy phosphate is fixed up by certain accumulation mode and frame structure; At this moment just osteoporosis can take place, bone calcium gets into blood plasma, causes blood calcium concentration too high; Just have calcium and discharge, thus the calcium deficiency of causing.
Therefore, the best method of replenishing the calcium often is exactly, replenish the collagen that has combined calcium in time, and after such calcium tonic got into human body, digestion, absorptance were very fast, and can comparatively fast arrive skeletal sites and deposit.
And at present on the market a lot of calcium-supplementing preparations mostly exist and only pay attention to additional calcium, and have ignored replenishing collagen, cause the unfavorable defective of effect of replenishing the calcium.
Summary of the invention
The object of the invention is to provide a kind of strong gelatine protocalcium electuary, mostly exists and only pays attention to additional calcium to solve in the prior art existing calcium-supplementing preparation, and ignored replenishing collagen, the technical matters of the unfavorable defective of effect that causes replenishing the calcium.
The object of the invention realizes through following technical scheme:
A kind of strong gelatine protocalcium electuary, it contains the following compositions in weight portion:
Milk calcium: 14-18 part,
Hydrolyzed Collagen: 50-70 part,
The colostrum basic protein: 1-2 part,
Vitamin D: 0.00001-0.00002 part,
Vitamin K: 0.00001-0.00002 part.
Preferably, it contains the following compositions in weight portion:
Milk calcium: 15 parts,
Hydrolyzed Collagen: 60 parts,
The colostrum basic protein: 1 part,
Vitamin D: 0.00001 part,
Vitamin K: 0.00001 part.
Compared with prior art, contain more collagen in the strong gelatine protocalcium electuary of the present invention, make that calcium tonic gets into human body after, and collagen can make calcium comparatively fast arrive skeletal sites to deposit, really play the effect of solid calcium, advantages of good calcium supplying effect.
The specific embodiment
Below in conjunction with embodiment, describe the present invention in detail.Following examples only are used to illustrate the present invention, are not used for limiting scope of the present invention.
Strong gelatine protocalcium electuary of the present invention, it contains the following compositions in weight portion:
Milk calcium: 14-18 part,
Hydrolyzed Collagen: 50-70 part,
The colostrum basic protein: 1-2 part,
Vitamin D: 0.00001-0.00002 part,
Vitamin K: 0.00001-0.00002 part.
It below is a most preferred embodiment of the present invention.It contains the following compositions in weight portion:
Milk calcium: 15 parts,
Hydrolyzed Collagen: 60 parts,
The colostrum basic protein: 1 part,
Vitamin D: 0.00001 part,
Vitamin K: 0.00001 part.
After fully mixing in the pulvis adding blender of said ratio requirement with milk calcium (newborn mineral salt, calcic 24-28%), Hydrolyzed Collagen, colostrum basic protein, vitamin D and vitamin K, can make finished product by quantitative package.
Method for using: these article are pulvis, ante cibum one after each meal all can, get finished product be dissolved in right amount stir in an amount of warm boiling water or the milk promptly drinkable.
Beneficial effect is analyzed:
One, the beneficial effect analysis of milk calcium
Milk calcium also is whey calcium; Be from milk, extract calcareous; The combination of the one type of mineral salt that obtains after process dehydration, degreasing, the dry spraying; Its calcic 24-28%; It is of high nutritive value, and composition comprises calcium citrate, calcium phosphate, ionized calcium, also contains rich nutrient contents such as zinc, phosphorus, protein, immunoglobulin (Ig), growth factor, lactoferrin; In all calcium classes, cow's milk calcium is absorbed by the body the most easily.Calcium in the cow's milk calcium powder, phosphorus ratio are coordinated rationally, and its naturally occurring vitamin D, CPP natural nutrition compositions such as (CPP) all are the factors that best help calcium absorbs.
It is the separable ionic condition that appears that milk calcium does not need too many hydrochloric acid in gastric juice to participate in human body, and then is directly absorbed by human body, regulates the blood calcium balance rapidly, builds up health.Milk calcium be all of generally acknowledging calcareous in " bioavailability " the highest food-grade calcium complement agent because also have an amount of albumen and reasonably calcium, phosphorus ratio 2 ︰ 1 in the milk calcium; Simultaneously, because have no chemical composition and technology in its production process, intestines and stomach had no burden.
Milk calcium is the high lactoprotein calcium of pure natural active that directly from milk, extracts; Owing to contain abundant lactose and albumen in the cow's milk; So its absorptivity is much higher than other food and common calcium; Its absorptivity is up to 62%-70%; Be calcium carbonate and calcium gluconae 2.5 times; Being 1.75 times of calcium lactate, is 5.5 times of shellfish calcium.
Two, the beneficial effect analysis of Hydrolyzed Collagen
Hydrolyzed Collagen can make after fish-skin or fish scale hydrolysis.Scientific research proves; Sclerotin mainly is made up of calcium and collagen; The loss of collagen and shortage can cause the undesirable of the assimilation effect of replenishing the calcium; Making replenishes the calcium is difficult to reach science state; Only Collagen material enriches under the effective prerequisite in guaranteeing body, and the bone health problem just can obtain real improvement and solution.When human body lacks collagen, then difficult fixing calcareous, cause calcium loss, cause bone density to reduce, form osteoporosis.1000 daltonian collagens can be repaired the collagen network structure of disintegration in the bone, and the toughness of enhances skeletal, elasticity can be recovered normal bone density.Therefore, suitably replenishing collagen helps to prevent in advance the healing of osteoporotic generation or fracture back damaged part, and safeguards articulation health.
Because collagen is the main component of articular cartilage tissue, be responsible for the framework of structure cartilaginous tissue.Therefore, replenish an amount of collagen, can keep the automatic generting machanism of human body self cartilaginous tissue, the protection joint avoids wearing and tearing and damages, and also can prevent the osteoarthritis that is caused by a variety of causes in advance; Also have the hairdressing function, because the nutrition source of hair is a subcutaneous tissue of scalp, replenishing collagen in good time can provide enough nutriment in order to regeneration, nutrition hair for subcutaneous tissue of scalp; Also skin health is had good health care improvement effect, can play preserve moisture, wrinkle resistant, repair, make skin moisten gloss more; Also can improve body immunity, collagen contains the amino acid that human body can't synthesize, and an amount of replenishing helps to strengthen each tissue organ function, improves body immunity.
The relation of calcium in collagen and the body, comprised two aspects: the hydroxyproline that comes from collagen in (1) blood plasma is the delivery vehicle that the calcium in the blood plasma is transported to osteocyte; (2) collagen in the bone tissue is the binder of calcium hydroxy phosphate, and calcium hydroxy phosphate and ossein have constituted the main body of bone.
Therefore, replenishing of calcium agent is not primary when replenishing the calcium, and importantly collagen replenishes and metabolism.
Three, the beneficial effect analysis of colostrum basic protein
Discover that the metabolism of bone may further comprise the steps:
(1) blood is transported to osteoclast on the bone;
(2) osteoclast is attached on the bone then, and osteoclast disengages acidic materials and ferment dissolving and destroys sclerotin;
(3) after step (2) work was accomplished, osteoclast just can disappear, and osteoblast occurs;
(4) osteoblast is made ossein and is enclosed one deck stickum, and afterwards, calcareous the investing on the ossein in the blood forms healthy bone.
Colostrum basic protein (CBP) is the low-molecular-weight activated protein of from colostrum, separating; Can carry out bidirectional modulation to bone cells; CBP can suppress the osteoclast activity on the one hand; Can promote osteoblast quantity to increase and liveness on the other hand; Be maintained in osteocyte and osteoclast dynamic benign balance, allow human body active absorption calcium, pin calcium; Thereby enhance bone density and length promote bone health.
CBP promotes the concrete manifestation of bone health to comprise:
1) is increased in the osteoblast quantity of bone;
2) stimulate osteoblast to make ossein;
3) help and absorb calcareously, prevent calcium loss;
4) suppress the osteoclast activity;
5) balance between adjusting osteoclast and the osteoblast is regulated bone metabolism.
Four, the beneficial effect analysis of vitamin D
Vitamin D is the accelerating agent of calcium absorption that product the most often uses of replenishing the calcium, and it can promote calcium at small intestine, or even intracolic absorption.Vitamin D is mainly used in composition and keeps the strong of bone.Only recognize that in present stage vitamin D promotes the absorption of calcium, phosphorus; Calcium, phosphorus can be mobilized from bone again; Make plasma calcium, phosphorus reach normal value; But also synthesize a kind of calbindin in the inductor; It helps calcium and passes through the absorption of the transhipment of intestines wall with enhancement calcium; Impel bone to mineralize, and bring in constant renewal in.It is used to prevent and treat children's rickets and adult's rickets, arthralgia or the like.The people who suffers from osteoporosis can effectively improve the trap of calcium ion through interpolation suitable vitamins D and magnesium.In addition, vitamin D also is used to reduce the probability of colon cancer, breast cancer and prostate cancer, and immune system is also had humidification.
Five, the beneficial effect analysis of vitamin K
Vitamin K is a bone calcium metabolism factor of influence.Osteocyte is mainly synthetic by mineral calcium and protein, discovers recently, and the synthetic bone cell needs vitamin K to participate in, and it can strengthen the affinity of protein to calcium, acts synergistically with vitamin D.Can more effective raising body to the absorption rate of calcium.Vitamin K is participated in the osteocyte metabolism, helps to increase the elderly's bone density especially, thereby can reduce the probability that fracture takes place because of osteoporosis the old man.
Also have data to show, vitamin K can reduce calcium through the excretion of kidney in urine, helps keeping the concentration of human body blood calcium, and calcium balance has positive influences in the body to keeping.
Research finds that also vitamin K also has the bone of participation metabolism, can increase osteoblastic synthesizing, and suppresses the generation of osteoclast, promotes the formation of bone, reduces the catabolism of bone.
Contain more collagen in the strong gelatine protocalcium electuary of the present invention, make that calcium tonic gets into human body after, and collagen can make calcium comparatively fast arrive skeletal sites to deposit, really play the effect of solid calcium, advantages of good calcium supplying effect.
More than disclosed only be several specific embodiments of the application, but the application is not limited thereto, any those skilled in the art can think variation, all should drop in the application's the protection domain.
Claims (2)
1. strong gelatine protocalcium electuary is characterized in that it contains the following compositions in weight portion:
Milk calcium: 14-18 part,
Hydrolyzed Collagen: 50-70 part,
The colostrum basic protein: 1-2 part,
Vitamin D: 0.00001-0.00002 part,
Vitamin K: 0.00001-0.00002 part.
2. strong gelatine protocalcium electuary as claimed in claim 1 is characterized in that it contains the following compositions in weight portion:
Milk calcium: 15 parts,
Hydrolyzed Collagen: 60 parts,
The colostrum basic protein: 1 part,
Vitamin D: 0.00001 part,
Vitamin K: 0.00001 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103115249A CN102349653A (en) | 2011-10-14 | 2011-10-14 | Bone-invigorating collagen calcium granules |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103115249A CN102349653A (en) | 2011-10-14 | 2011-10-14 | Bone-invigorating collagen calcium granules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102349653A true CN102349653A (en) | 2012-02-15 |
Family
ID=45573380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011103115249A Pending CN102349653A (en) | 2011-10-14 | 2011-10-14 | Bone-invigorating collagen calcium granules |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102349653A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784472A (en) * | 2012-10-30 | 2014-05-14 | 上海诺成药业股份有限公司 | A calcium preparation, a preparing method thereof and applications thereof |
| CN104026239A (en) * | 2014-06-26 | 2014-09-10 | 光明乳业股份有限公司 | Bone-strengthened milk and preparation method thereof |
| CN104487061A (en) * | 2012-07-24 | 2015-04-01 | J-制油株式会社 | Composition |
| CN104705658A (en) * | 2015-04-09 | 2015-06-17 | 四川健之源科技有限公司 | Health food with bone density improving function |
| CN104721230A (en) * | 2015-04-13 | 2015-06-24 | 福州乾正药业有限公司 | Composite of milk basic protein and milk mineral, preparation method thereof and application |
| CN105056216A (en) * | 2015-09-23 | 2015-11-18 | 北京里肯营养科学研究有限公司 | Calcium supplementing preparation/granule and preparation method thereof |
| CN105194657A (en) * | 2015-09-18 | 2015-12-30 | 威海康宝生物科技开发有限公司 | Preparation for increasing bone density and preparation method thereof |
| CN107318927A (en) * | 2017-08-28 | 2017-11-07 | 张志雄 | A kind of biscuit cake |
| CN114343187A (en) * | 2021-12-27 | 2022-04-15 | 北京康比特体育科技股份有限公司 | Health beverage containing collagen tripeptide and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455396A (en) * | 2009-01-07 | 2009-06-17 | 成都自豪药业有限公司 | Nutrient health-care food capable of promoting bone and bone arthrosis health |
| CN101911976A (en) * | 2010-07-30 | 2010-12-15 | 生命阳光(广州)营养品有限公司 | Milk calcium formula nutritional powder |
| CN102091324A (en) * | 2011-03-15 | 2011-06-15 | 徐世祥 | Calcium for nourishing bones |
-
2011
- 2011-10-14 CN CN2011103115249A patent/CN102349653A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455396A (en) * | 2009-01-07 | 2009-06-17 | 成都自豪药业有限公司 | Nutrient health-care food capable of promoting bone and bone arthrosis health |
| CN101911976A (en) * | 2010-07-30 | 2010-12-15 | 生命阳光(广州)营养品有限公司 | Milk calcium formula nutritional powder |
| CN102091324A (en) * | 2011-03-15 | 2011-06-15 | 徐世祥 | Calcium for nourishing bones |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104487061A (en) * | 2012-07-24 | 2015-04-01 | J-制油株式会社 | Composition |
| CN108057117B (en) * | 2012-07-24 | 2021-05-18 | J-制油株式会社 | Use of a composition comprising collagen hydrolysate |
| CN108057117A (en) * | 2012-07-24 | 2018-05-22 | J-制油株式会社 | The purposes of composition comprising collagen hydrolysate |
| EP2878295A4 (en) * | 2012-07-24 | 2015-12-23 | J Oil Mills Inc | Composition |
| CN103784472B (en) * | 2012-10-30 | 2016-06-29 | 上海诺成药业股份有限公司 | A kind of calcium preparation and its production and use |
| CN103784472A (en) * | 2012-10-30 | 2014-05-14 | 上海诺成药业股份有限公司 | A calcium preparation, a preparing method thereof and applications thereof |
| CN104026239A (en) * | 2014-06-26 | 2014-09-10 | 光明乳业股份有限公司 | Bone-strengthened milk and preparation method thereof |
| CN104705658A (en) * | 2015-04-09 | 2015-06-17 | 四川健之源科技有限公司 | Health food with bone density improving function |
| CN104721230A (en) * | 2015-04-13 | 2015-06-24 | 福州乾正药业有限公司 | Composite of milk basic protein and milk mineral, preparation method thereof and application |
| CN105194657A (en) * | 2015-09-18 | 2015-12-30 | 威海康宝生物科技开发有限公司 | Preparation for increasing bone density and preparation method thereof |
| CN105056216A (en) * | 2015-09-23 | 2015-11-18 | 北京里肯营养科学研究有限公司 | Calcium supplementing preparation/granule and preparation method thereof |
| CN107318927A (en) * | 2017-08-28 | 2017-11-07 | 张志雄 | A kind of biscuit cake |
| CN114343187A (en) * | 2021-12-27 | 2022-04-15 | 北京康比特体育科技股份有限公司 | Health beverage containing collagen tripeptide and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102349653A (en) | Bone-invigorating collagen calcium granules | |
| CN101317684B (en) | Solid beverage and preparation method there of | |
| CN107535610A (en) | A kind of formula milk and its production method for contributing to skeleton health | |
| CN101692908B (en) | Double-glue pollen food with functions of enriching blood, beautifying face and nourishing skin and preparation method thereof | |
| CN102356877A (en) | CBP calcium supplement electuary | |
| CN101268835B (en) | Nutrition high calcium medicinal granule for children and preparing technique | |
| CN110403116A (en) | A kind of donkey-hide gelatin peptide solid beverage and preparation method thereof | |
| CN104939054A (en) | Health food capable of enhancing bone mineral density and immunity and preparation method of health food | |
| CN104222999A (en) | Composition, preparation and application of novel low sodium salt | |
| CN105494647B (en) | A kind of calcium fortification milk powder and preparation method thereof | |
| US20180184699A1 (en) | Process for the preparation of an additive as a food supplement based on seaweeds for birds and animals; as well as the product obtained and its use in the food conversion and in the production of bird and animal meat | |
| CN111657364A (en) | Formula milk powder | |
| CN109198647A (en) | A kind of nutritional preparation that can improve spacefarer's bony structures | |
| CN104432029A (en) | Health food for increasing bone density | |
| CN104222699A (en) | Marten feed and feeding method for marten | |
| CN115399449A (en) | Preparation method of bone nutrition snowflake tablets | |
| CN104824660A (en) | Collagen-saussurea involucrata small peptide effervescent tablet and preparation method thereof | |
| CN107535609A (en) | A kind of formula milk and its production method for contributing to adult female's health | |
| CN111134244A (en) | Animal high-protein nutritional paste and preparation method thereof | |
| CN101711568A (en) | Seafood seasoning and preparation method thereof | |
| CN101856494A (en) | Composition for improving immunity and preparation method thereof | |
| CN107969649A (en) | One kind is replenished the calcium composition and preparation method | |
| CN106417619A (en) | Milk calcium powder for promoting skeleton growth and enhancing immunity | |
| CN104432099A (en) | Health food containing vitamin K2 | |
| CN109169927A (en) | Calcium-rich yak milk powder, preparation method thereof and fermented milk product |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20120215 |