CN102348463B - 白介素-22在预防和/或治疗多器官功能障碍综合症(mods)中的用途 - Google Patents

白介素-22在预防和/或治疗多器官功能障碍综合症(mods)中的用途 Download PDF

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Publication number
CN102348463B
CN102348463B CN201080010768.7A CN201080010768A CN102348463B CN 102348463 B CN102348463 B CN 102348463B CN 201080010768 A CN201080010768 A CN 201080010768A CN 102348463 B CN102348463 B CN 102348463B
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multiple organ
organ dysfunction
dysfunction syndrome
mods
interleukin
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Chinese (zh)
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CN102348463A (zh
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黄予良
黄智华
孙琪
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Yiyi Biomedical Development Shanghai Co ltd
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Generon Shanghai Corp Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2066—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN201080010768.7A 2009-01-12 2010-01-11 白介素-22在预防和/或治疗多器官功能障碍综合症(mods)中的用途 Active CN102348463B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14413409P 2009-01-12 2009-01-12
US61/144,134 2009-01-12
PCT/US2010/020673 WO2010081112A1 (en) 2009-01-12 2010-01-11 Prevention and/or treatment of multiple organ dysfunction syndrome with interleukin-22

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CN102348463A CN102348463A (zh) 2012-02-08
CN102348463B true CN102348463B (zh) 2014-05-07

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CN201080010768.7A Active CN102348463B (zh) 2009-01-12 2010-01-11 白介素-22在预防和/或治疗多器官功能障碍综合症(mods)中的用途

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US (1) US8956605B2 (cg-RX-API-DMAC7.html)
EP (1) EP2385841B1 (cg-RX-API-DMAC7.html)
JP (1) JP5981141B2 (cg-RX-API-DMAC7.html)
CN (1) CN102348463B (cg-RX-API-DMAC7.html)
AU (1) AU2010203446B2 (cg-RX-API-DMAC7.html)
CA (1) CA2748392C (cg-RX-API-DMAC7.html)
WO (1) WO2010081112A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361968B (zh) 2007-08-06 2011-08-03 健能隆医药技术（上海）有限公司 白介素-22在治疗脂肪肝中的应用
LT2970422T (lt) 2013-03-15 2018-06-25 F. Hoffmann-La Roche Ag Il-22 polipeptidai ir il-22 su fc sulieti baltymai bei panaudojimo būdai
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 Il-22二聚体在制备静脉注射药物中的应用
WO2017181143A1 (en) 2016-04-15 2017-10-19 Generon (Shanghai) Corporation, Ltd. Use of il-22 in treating necrotizing enterocolitis
CN112007146A (zh) * 2020-09-03 2020-12-01 上海市儿童医院 Il-22在治疗和/或预防脓毒症诱发的肝脏损伤的药物中的用途
WO2022191828A1 (en) * 2021-03-10 2022-09-15 Wen Tan NEW USE OF (R)-β2-AGONISTS IN TREATMENT OF SEPSIS AND ACUTE RESPIRATORY DISTRESS SYNDROME

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070207943A1 (en) * 1998-05-29 2007-09-06 Human Genome Sciences, Inc. Interleukins-21 and 22

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010023070A1 (en) * 1998-05-29 2001-09-20 Reinhard Ebner Interleukins-21 and 22
US7226591B2 (en) * 2000-05-22 2007-06-05 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US20050148029A1 (en) * 2003-09-29 2005-07-07 Biosite, Inc. Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes
CN100515491C (zh) * 2005-01-04 2009-07-22 健能隆医药技术（上海）有限公司 白介素-22的医药用途
CN101219208B (zh) * 2005-01-04 2010-08-11 健能隆医药技术（上海）有限公司 白介素-22的医药用途
JP2009541338A (ja) * 2006-06-19 2009-11-26 ワイス Ｉｌ−２２およびｉｌ−１７の調節方法
WO2008085229A2 (en) * 2006-11-15 2008-07-17 Arteriocyte Inc. Cell-based therapies for treating liver disease
CN101168049A (zh) * 2007-10-23 2008-04-30 中国人民解放军军事医学科学院基础医学研究所 白介素-22在制备治疗肝病药物中的应用及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070207943A1 (en) * 1998-05-29 2007-09-06 Human Genome Sciences, Inc. Interleukins-21 and 22

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
多器官功能障碍综合征的进展;甘枚 等;《医学综述》;20060731;第12卷(第14期);862-865 *

Also Published As

Publication number Publication date
US8956605B2 (en) 2015-02-17
EP2385841A4 (en) 2012-12-19
JP5981141B2 (ja) 2016-08-31
CA2748392C (en) 2017-06-27
CA2748392A1 (en) 2010-07-15
CN102348463A (zh) 2012-02-08
JP2012515165A (ja) 2012-07-05
EP2385841B1 (en) 2016-11-16
AU2010203446B2 (en) 2015-12-17
EP2385841A1 (en) 2011-11-16
US20110268696A1 (en) 2011-11-03
AU2010203446A1 (en) 2011-07-14
WO2010081112A1 (en) 2010-07-15

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Denomination of invention: Prevention and/or treatment of multiple organ dysfunction syndrome with interleukin-22

Effective date of registration: 20140617

Granted publication date: 20140507

Pledgee: Pudong Shanghai technology financing Company limited by guarantee

Pledgor: Generon (Shanghai) Corporation Ltd.

Registration number: 2014310000038

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Address after: 201203 Room 302 / 303, building 9, Lane 1011, Halley Road, Zhangjiang hi tech, Pudong New Area, Shanghai

Patentee after: Yiyi biomedical development (Shanghai) Co.,Ltd.

Address before: 201203 Room 302 / 303, building 9, Lane 1011, Halley Road, Zhangjiang hi tech, Pudong New Area, Shanghai

Patentee before: GENERON (SHANGHAI) Corp.,Ltd.

PC01 Cancellation of the registration of the contract for pledge of patent right
PC01 Cancellation of the registration of the contract for pledge of patent right

Date of cancellation: 20210628

Granted publication date: 20140507

Pledgee: Pudong Shanghai technology financing Company limited by guarantee

Pledgor: GENERON (SHANGHAI) Corp.,Ltd.

Registration number: 2014310000038