CN102335404A - Oral Chinese medicinal composition for treating senile dementia - Google Patents
Oral Chinese medicinal composition for treating senile dementia Download PDFInfo
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- CN102335404A CN102335404A CN2011103081045A CN201110308104A CN102335404A CN 102335404 A CN102335404 A CN 102335404A CN 2011103081045 A CN2011103081045 A CN 2011103081045A CN 201110308104 A CN201110308104 A CN 201110308104A CN 102335404 A CN102335404 A CN 102335404A
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Abstract
The invention provides an oral Chinese medicinal composition for treating senile dementia. The Chinese medicinal composition for treating senile dementia comprises the following components in part by weight: 7 to 11 parts of peach kernel, 7 to 11 parts of safflower, 9 to 15 parts of red paeony root, 9 to 15 parts of ligusticum wallichii, 9 to 15 parts of acorus gramineus, 7 to 11 parts of zedoary, 4 to 8 parts of welsh onion, 4 to 8 parts of ginger and 9 to 15 parts of geosaurus. Compared with the prior art, the oral Chinese medicinal composition can treat senile dementia by differentiation of symptoms and signs aiming at the internal pathogenic factors of senile dementia, has quick response, and an obvious effect, is low in cost, does not have toxic or side effect and can address both the symptoms and root causes.
Description
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine composition of orally taken for curing alzheimer disease.
Background technology
Alzheimer disease is that acquired cerebral cortex Premium Features damage comprehensively, shows as generally the going down or lose of control ability etc. of memory, judgment, sensation and motor function, speech, daily life active ability, social function, interpersonal communication, emotional responses.Slow-witted and stupid, but do not have disturbance of consciousness, can regard a syndrome as.The western medical treatment alzheimer disease adopts cholinesterase inhibitor more, but side effect such as that this type medicine has is nauseating, vomiting can bring serious burden to liver and kidney metabolism.On the traditional Chinese medical science, alzheimer disease belongs to categories such as the traditional Chinese medical science " literary composition is silly ", " forgetful ", " dementia ", " melancholia ".
Summary of the invention
The Chinese medicine composition that the purpose of this invention is to provide a kind of orally taken for curing alzheimer disease, it is to the inherent pathogenic factor of alzheimer disease, distinguishes that disease executing control, and with strong points, curative effect is fast, and cost is low, and has no side effect, and can reach to play good prevention effect.
The traditional Chinese medical science thinks that the cause of disease of alzheimer disease behaves to person in middle and old age, and the internal organs QI and blood all loses, if inappropriate because of resting again, intemperate sexual intercourse consumes excess of four natures in foods or drugs causing damage of essence and undermines Liver and kidney; Or after the serious disease prolonged illness, or the later stage of mental diseases and apoplexy, pathogenic heat lingering, damage qi-blood-body fluid; Or be angry, or drink and be satiated with food, impairing the liver and spleen because of being worried; Or troubled thoughts pent-up with the passing of time, causes qi depression to blood stasis; Or undermine the brain mansion outward because of injuring to poison.Pathological change is old or prolonged illness, and internal organs void declines, and brains are not enough, yang imbalance, and conversion is not normal each other between the QI and blood marrow, and ascending or descending movement of vital Qi is disorderly contrary, the stagnation of phlegm blood stasis, and cause brain siddhi dysfunction and even clinical all disease peaks to rise.Viscera YIN yang-energy blood deficiency declines, vital essence can not on gather in head, deficiency of marrow-reservoir, gods lose to be supported, malfunction can not be driven body and face nine orifices outward, gradually to dull-witted generation.The pathology of primary disease is positioned at brain (marrow), and is relevant with internal organs such as the heart, kidney,liver,spleens.
The present invention adopts following technical scheme: a kind of Chinese medicine composition of orally taken for curing alzheimer disease in weight portion, comprises following component: Semen Persicae 7-11, Flos Carthami 7-11; Radix Paeoniae Rubra 9-15, Rhizoma Chuanxiong 9-15, Rhizoma Acori Graminei 9-15, Radix Curcumae 7-11; Herba Alii fistulosi 4-8, Rhizoma Zingiberis Recens 4-8, Pheretima 9-15.
The Analysis on Mechanism of Chinese medicine of the present invention:
Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation." medication heart method ": Semen Persicae, bitter to let out stagnant blood, sweet with tissue regeneration promoting blood, so blood coagulation must be used.Heat in dehematizing again.
Flos Carthami: acrid in the mouth; Warm in nature.GUIXIN; The tripe warp.Invigorate blood circulation can through; Stasis-dispelling and pain-killing." book on Chinese herbal medicine just ": reach variola heat in blood difficulty and go out, the stasis of speckle rash does not disappear.
Radix Paeoniae Rubra: bitter in the mouth, cold nature.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection." Japan hanako materia medica ": control wind and mend labor, all diseases in sick and antenatal back of main woman, Tong Yueshui, the relieving restlessness of bringing down a fever, QI invigorating, day hot disease of row, pestilence miasma mania and irritation, married woman's blood fortune, and hemorrhoidal hamorrhage rushes down blood; Hemorrhoid complicated by anal fistula, carbuncle on the back, skin ulcer scabies, headache makes eye bright conjunctival congestion, bulbar conjunctiva polyp.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping." herbal classic ": main apoplexy is gone into the brain headache, arthralgia due to cold, and the clonic spasm of the muscle emergency, the gold wound, married woman's blood closes loss of fecundity.
Rhizoma Acori Graminei: acrid in the mouth; Bitter; Slightly warm in nature.GUIXIN; Liver; Spleen channel.Waking up the patient from unconsciousness by dissipating phlegm; The removing dampness circulation of qi promoting; The sharp numbness of dispeling the wind; Reducing swelling and alleviating pain.Cure mainly calentura coma, syncope due to accumulation of phlegm, forgetful, tinnitus, deafness, abdominal distention, fasting dysentery, rheumatic arthralgia, traumatic injury, carbuncle scabies." book on Chinese herbal medicine converge with speech ": Rhizoma Acori Graminei, promoting the circulation of QI is sensible, as because of phlegm-fire two heresy be eyes afflicted with calaract, causes that gas has some setbacks, the obstructed person of key, clothes should be so.If deficiency of QI in middle-JIAO, hungry in the spirit, the gas key does not have yang-energy and moves and obstructed person for it, sees repeatly and uses decoction of ten powerful tonics, and it is extremely many to yield result, and Rhizoma Acori Graminei needn't be asked also.
Radix Curcumae: acrid in the mouth; Bitter; Cold in nature.GUIXIN; Liver; Gallbladder meridian.Invigorate blood circulation and end ability; Promoting QI circulation for relieving depression; Removing heat from blood clears away heart-fire; Depressed liver-energy dispersing and function of gallbladder promoting.Be used for all pains of breast abdomen side of body rib, dysmenorrhes; Amenorrhea, the lump in the abdomen caking, the calentura coma, demented, infantile convulsion is spitted blood, and nosebleed is equipped with, stranguria with blood, sand Stranguria, jaundice.Tang Materia Medica: main accumulation of blood, the therapeutic method to keep the adverse QI flowing downwards, granulation promoting, hemostasis, broken stagnant blood, stranguria with blood, hematuria, incised wound.
Herba Alii fistulosi: warm in nature, acrid in the mouth is flat.Go into lung, stomach two warps.Clearing away heat and eliminating dampness; Detoxifcation.Relieving the exterior syndrome by diaphoresis, dispelling cold and activating YANG, detoxifcation is loose and is coagulated.Cure mainly the light disease of anemofrigid cold, carbuncle sore tumefacting virus, dysentery faint pulse, cold coagulation stomachache, diseases such as dysuria.
Rhizoma Zingiberis Recens: acrid in the mouth, hot in nature.Return spleen, stomach, the heart, lung meridian.Warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention." herbal classic ": main fullness in the chest cough with dyspnea, warming middle-JIAO, hemostasis is perspired, by rheumatism numbness, intestinal the Lushui River dysentery.The survivor is good especially.
Pheretima: salty, cold.Return liver, spleen, urinary bladder channel.The heat clearing away arresting convulsion, collateral dredging is relievingd asthma, diuresis.Be used for unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
To the diabetes insipidus of caused by energy stagnation and blood stasis, the traditional Chinese medical science thinks that assertive evidence has trauma history more, and the brain being the house of mentality like stagnation of QI and blood, can not normally supplement nutrition in brain QI and blood, or because of blood stasis retardance venation, QI-blood failing to nourish upward supports refreshing mistake of brain in brain, then can send out to be dementia; The body of the tongue purple is dim, and slow pulse is puckery etc., is levying of blood stasis.
The person of choosing in the side, promoting flow of QI and blood, sensible refreshment, Semen Persicae blood circulation promoting and blood stasis dispelling; Flos Carthami invigorate blood circulation can through; The Radix Paeoniae Rubra clearing away heat and cooling blood; The Rhizoma Chuanxiong blood-activating and qi-promoting; The Rhizoma Acori Graminei circulation of qi promoting of having one's ideas straightened out; The Radix Curcumae promoting QI circulation for relieving depression; The Herba Alii fistulosi clearing away heat and eliminating dampness; The expectorant of Rhizoma Zingiberis Recens dampness; Pheretima heat clearing away arresting convulsion.Play altogether full side, nourishing the essence and strengthening QI, and foster brain is calmed the nerves, balance body negative and positive.To caused by energy stagnation and blood stasis alzheimer disease determined curative effect, prevention effect is remarkable, double taking stopgap measures originally.
Form of Chinese drug of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
To the Chinese medicine composition of 40 alzheimer disease patients (age 60-78) use orally taken for curing alzheimer disease of the present invention, 1 course of treatment of continued treatment (1 month), wherein 15 examples are cured fully, transference cure; 18 routine remissions, seizure frequency reduce; Invalid 7 examples, overall effective percentage reaches 82.5%.
Instance:
The patient 1: Liu, and the women, 62 years old, suffered from senile dementia before 2 years, symptom is dizzy, tinnitus, forgetful, personality changes to some extent, is reluctant to exchange with the people, is over-suspicious all day long, and intelligence descends to some extent.The Chinese medicine composition of treatment alzheimer disease of the present invention is used in the back, and after 1 course of treatment, above-mentioned symptom is eased, and intelligence spirit all has improvement, and dizzy, tinnitus transference cure continues 1 month course of treatment of medication, and above-mentioned symptom all disappears.
The patient 2: military certain, the male 65 years old, the alzheimer disease symptom occurred before 1 year.Often forgetful, disturbance of orientation to place appears, the easy disorientation of going out, obstacle appears in language function, likes to murmur to oneself, and the logicality of speaking is poor.Use upon somebody's introduction and take Chinese medicine composition of the present invention, uses 1 course of treatment after, above-mentioned symptom is eased, patient's emotion is stablized gradually, forgetful sx, it is clear that thinking also becomes, after adhere to taking medicine always, above-mentioned symptom all disappears.
The patient 3: Chen, and the women, 70 years old, suffered from alzheimer disease 4 years, be slow in action, obstacle appears in verbal function, and the hypophrenia, memory become very poor, often forget the thing of just having done, and look often occurs dull.Use the Chinese medicine composition of treatment alzheimer disease of the present invention to treat, after 2 courses of treatment, aphasis obviously alleviates, and spirit is recovered to some extent, forgetful sx, and continued is taken medicine and is controlled, and above-mentioned symptom disappears basically.
The specific embodiment
In order to understand the present invention better, through embodiment the present invention is described below.
Embodiment 1
A kind of Chinese medicine composition of orally taken for curing alzheimer disease in weight portion, comprises following component: Semen Persicae 71, Flos Carthami 71, Radix Paeoniae Rubra 9, Rhizoma Chuanxiong 9, Rhizoma Acori Graminei 9, Radix Curcumae 7, Herba Alii fistulosi 4, Rhizoma Zingiberis Recens 4, Pheretima 9.
Its preparation method is:
In weight portion, get Semen Persicae 71, Flos Carthami 71, Radix Paeoniae Rubra 9, Rhizoma Chuanxiong 9, Rhizoma Acori Graminei 9, Radix Curcumae 7, Herba Alii fistulosi 4, Rhizoma Zingiberis Recens 4, Pheretima 9; Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag.
Embodiment 2
A kind of Chinese medicine composition of orally taken for curing alzheimer disease in weight portion, comprises following component: Semen Persicae 11, Flos Carthami 11, Radix Paeoniae Rubra 15, Rhizoma Chuanxiong 15, Rhizoma Acori Graminei 15, Radix Curcumae 11, Herba Alii fistulosi 8, Rhizoma Zingiberis Recens 8, Pheretima 15.
Its preparation method is:
In weight portion, get Semen Persicae 11, Flos Carthami 11, Radix Paeoniae Rubra 15, Rhizoma Chuanxiong 15, Rhizoma Acori Graminei 15, Radix Curcumae 11, Herba Alii fistulosi 8, Rhizoma Zingiberis Recens 8, Pheretima 15; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
A kind of Chinese medicine composition of orally taken for curing alzheimer disease in weight portion, comprises following component: Semen Persicae 9, Flos Carthami 9, Radix Paeoniae Rubra 12, Rhizoma Chuanxiong 12, Rhizoma Acori Graminei 12, Radix Curcumae 9, Herba Alii fistulosi 6, Rhizoma Zingiberis Recens 6, Pheretima 12.
Its preparation method is:
In weight portion, get Semen Persicae 9, Flos Carthami 9, Radix Paeoniae Rubra 12, Rhizoma Chuanxiong 12, Rhizoma Acori Graminei 12, Radix Curcumae 9, Herba Alii fistulosi 6, Rhizoma Zingiberis Recens 6, Pheretima 122; Cleaning, drying mix above-mentioned medical material, use pulverizer to pulverize and are 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing promptly gets pill.
Embodiment 4
A kind of Chinese medicine composition of orally taken for curing alzheimer disease in weight portion, comprises following component: Semen Persicae 9, Flos Carthami 9, Radix Paeoniae Rubra 12, Rhizoma Chuanxiong 12, Rhizoma Acori Graminei 12, Radix Curcumae 9, Herba Alii fistulosi 6, Rhizoma Zingiberis Recens 6, Pheretima 12.
Its preparation method is:
In weight portion, get Semen Persicae 9, Flos Carthami 9, Radix Paeoniae Rubra 12, Rhizoma Chuanxiong 12, Rhizoma Acori Graminei 12, Radix Curcumae 9, Herba Alii fistulosi 6, Rhizoma Zingiberis Recens 6, Pheretima 12; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Granule is processed the 0.4g/ capsules with the capsule filler.
Claims (4)
1. the Chinese medicine composition of an orally taken for curing alzheimer disease is characterized in that, in weight portion, comprises following component: Semen Persicae 7-11, Flos Carthami 7-11, Radix Paeoniae Rubra 9-15, Rhizoma Chuanxiong 9-15, Rhizoma Acori Graminei 9-15, Radix Curcumae 7-11, Herba Alii fistulosi 4-8, Rhizoma Zingiberis Recens 4-8, Pheretima 9-15.
2. Chinese medicine composition according to claim 1 is characterized in that, in weight portion, preferably comprises following component: Semen Persicae 9, Flos Carthami 9, Radix Paeoniae Rubra 12, Rhizoma Chuanxiong 12, Rhizoma Acori Graminei 12, Radix Curcumae 9, Herba Alii fistulosi 6, Rhizoma Zingiberis Recens 6, Pheretima 12.
3. Chinese medicine composition according to claim 1 is characterized in that, said Chinese medicine composition adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine composition according to claim 1 is characterized in that said Chinese medicine composition preferably adopts solution, granule, pill and capsule.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011103081045A CN102335404A (en) | 2011-10-12 | 2011-10-12 | Oral Chinese medicinal composition for treating senile dementia |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251884A (en) * | 2013-05-03 | 2013-08-21 | 杨文明 | Traditional Chinese medicine for treating Alzheimer disease as well as preparation method and application thereof |
| CN115919980A (en) * | 2022-10-17 | 2023-04-07 | 湖南省脑科医院(湖南省第二人民医院) | Traditional Chinese medicine composition for soothing nerves and relieving depression, traditional Chinese medicine preparation, and preparation method and application thereof |
-
2011
- 2011-10-12 CN CN2011103081045A patent/CN102335404A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251884A (en) * | 2013-05-03 | 2013-08-21 | 杨文明 | Traditional Chinese medicine for treating Alzheimer disease as well as preparation method and application thereof |
| CN115919980A (en) * | 2022-10-17 | 2023-04-07 | 湖南省脑科医院(湖南省第二人民医院) | Traditional Chinese medicine composition for soothing nerves and relieving depression, traditional Chinese medicine preparation, and preparation method and application thereof |
| CN115919980B (en) * | 2022-10-17 | 2024-05-31 | 湖南省脑科医院(湖南省第二人民医院) | Traditional Chinese medicine composition and traditional Chinese medicine preparation for soothing nerves and resolving depression as well as preparation method and application of traditional Chinese medicine composition and traditional Chinese medicine preparation |
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Application publication date: 20120201 |