CN102552793B - Chinese medicinal composition for treating unstable angina pectoris derived from aged coronary heart disease - Google Patents
Chinese medicinal composition for treating unstable angina pectoris derived from aged coronary heart disease Download PDFInfo
- Publication number
- CN102552793B CN102552793B CN2012100347889A CN201210034788A CN102552793B CN 102552793 B CN102552793 B CN 102552793B CN 2012100347889 A CN2012100347889 A CN 2012100347889A CN 201210034788 A CN201210034788 A CN 201210034788A CN 102552793 B CN102552793 B CN 102552793B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- medicinal composition
- chinese medicinal
- angina pectoris
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000007814 Unstable Angina Diseases 0.000 title claims abstract description 16
- 239000000203 mixture Substances 0.000 title claims abstract description 13
- 208000029078 coronary artery disease Diseases 0.000 title claims abstract description 11
- 239000003814 drug Substances 0.000 claims abstract description 28
- 241000218176 Corydalis Species 0.000 claims abstract description 13
- 241001506304 Kadsura japonica Species 0.000 claims abstract description 3
- 241000756943 Codonopsis Species 0.000 claims description 8
- 229940079593 drug Drugs 0.000 claims description 8
- 239000009636 Huang Qi Substances 0.000 claims description 6
- 206010002388 Angina unstable Diseases 0.000 claims description 5
- 201000004332 intermediate coronary syndrome Diseases 0.000 claims description 5
- 241000219780 Pueraria Species 0.000 claims description 2
- 241000545442 Radix Species 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 24
- 206010002383 Angina Pectoris Diseases 0.000 abstract description 11
- 239000008280 blood Substances 0.000 abstract description 8
- 210000004369 blood Anatomy 0.000 abstract description 8
- 230000017531 blood circulation Effects 0.000 abstract description 8
- 230000001737 promoting effect Effects 0.000 abstract description 8
- 230000001939 inductive effect Effects 0.000 abstract description 3
- 230000005906 menstruation Effects 0.000 abstract description 3
- 230000007170 pathology Effects 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract 2
- 241001127714 Amomum Species 0.000 abstract 1
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 244000236521 Bupleurum rotundifolium Species 0.000 abstract 1
- 235000015221 Bupleurum rotundifolium Nutrition 0.000 abstract 1
- 235000002566 Capsicum Nutrition 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 241000212322 Levisticum officinale Species 0.000 abstract 1
- 241000208682 Liquidambar Species 0.000 abstract 1
- 235000006552 Liquidambar styraciflua Nutrition 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 239000006002 Pepper Substances 0.000 abstract 1
- 235000016761 Piper aduncum Nutrition 0.000 abstract 1
- 235000017804 Piper guineense Nutrition 0.000 abstract 1
- 244000203593 Piper nigrum Species 0.000 abstract 1
- 235000008184 Piper nigrum Nutrition 0.000 abstract 1
- 244000046146 Pueraria lobata Species 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 240000000513 Santalum album Species 0.000 abstract 1
- 235000008632 Santalum album Nutrition 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 239000001645 levisticum officinale Substances 0.000 abstract 1
- 244000138993 panchioli Species 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 210000004233 talus Anatomy 0.000 abstract 1
- 239000002023 wood Substances 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 description 17
- 239000000796 flavoring agent Substances 0.000 description 16
- 235000019634 flavors Nutrition 0.000 description 16
- 208000002193 Pain Diseases 0.000 description 14
- 210000004185 liver Anatomy 0.000 description 10
- 210000002784 stomach Anatomy 0.000 description 9
- 230000007812 deficiency Effects 0.000 description 8
- 206010000087 Abdominal pain upper Diseases 0.000 description 6
- 201000000736 Amenorrhea Diseases 0.000 description 6
- 206010001928 Amenorrhoea Diseases 0.000 description 6
- 231100000540 amenorrhea Toxicity 0.000 description 6
- 230000003203 everyday effect Effects 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 208000006820 Arthralgia Diseases 0.000 description 5
- 206010012735 Diarrhoea Diseases 0.000 description 5
- 208000005171 Dysmenorrhea Diseases 0.000 description 5
- 206010013935 Dysmenorrhoea Diseases 0.000 description 5
- 210000000481 breast Anatomy 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 208000019255 Menstrual disease Diseases 0.000 description 4
- 210000001015 abdomen Anatomy 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 3
- 208000024172 Cardiovascular disease Diseases 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 206010037660 Pyrexia Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 210000004351 coronary vessel Anatomy 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 230000035922 thirst Effects 0.000 description 3
- 206010010774 Constipation Diseases 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 206010062575 Muscle contracture Diseases 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 208000025747 Rheumatic disease Diseases 0.000 description 2
- 206010046814 Uterine prolapse Diseases 0.000 description 2
- 208000022531 anorexia Diseases 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 208000006111 contracture Diseases 0.000 description 2
- 206010061428 decreased appetite Diseases 0.000 description 2
- IZEKFCXSFNUWAM-UHFFFAOYSA-N dipyridamole Chemical compound C=12N=C(N(CCO)CCO)N=C(N3CCCCC3)C2=NC(N(CCO)CCO)=NC=1N1CCCCC1 IZEKFCXSFNUWAM-UHFFFAOYSA-N 0.000 description 2
- 210000000232 gallbladder Anatomy 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 208000010125 myocardial infarction Diseases 0.000 description 2
- 231100000862 numbness Toxicity 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 206010037844 rash Diseases 0.000 description 2
- 230000000552 rheumatic effect Effects 0.000 description 2
- 206010040872 skin infection Diseases 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010002660 Anoxia Diseases 0.000 description 1
- 241000976983 Anoxia Species 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 208000037260 Atherosclerotic Plaque Diseases 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 239000001692 EU approved anti-caking agent Substances 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 206010018045 Gastroptosis Diseases 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 208000008238 Muscle Spasticity Diseases 0.000 description 1
- 206010028836 Neck pain Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010033425 Pain in extremity Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000007718 Stable Angina Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 206010000891 acute myocardial infarction Diseases 0.000 description 1
- 230000007953 anoxia Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- KRALOLGXHLZTCW-UHFFFAOYSA-L calcium;2-acetyloxybenzoate Chemical compound [Ca+2].CC(=O)OC1=CC=CC=C1C([O-])=O.CC(=O)OC1=CC=CC=C1C([O-])=O KRALOLGXHLZTCW-UHFFFAOYSA-L 0.000 description 1
- 208000015606 cardiovascular system disease Diseases 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 206010019847 hepatosplenomegaly Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- MOYKHGMNXAOIAT-JGWLITMVSA-N isosorbide dinitrate Chemical compound [O-][N+](=O)O[C@H]1CO[C@@H]2[C@H](O[N+](=O)[O-])CO[C@@H]21 MOYKHGMNXAOIAT-JGWLITMVSA-N 0.000 description 1
- 210000005240 left ventricle Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 230000003119 painkilling effect Effects 0.000 description 1
- 210000003516 pericardium Anatomy 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 201000001474 proteinuria Diseases 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229940093252 sorbitrate Drugs 0.000 description 1
- 208000018198 spasticity Diseases 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese medicinal composition for treating unstable angina pectoris derived from an aged coronary heart disease. The Chinese medicinal composition consists of the following bulk pharmaceuticals in parts by weight: 20-40 parts of astragalus, 10-20 parts of dangshen, 10-20 parts of red-rooted salvia root, 5-10 parts of sandalwood, 5-10 parts of amomum fruit, 10-15 parts of Chinese thorowax root, 10-15 parts of bitter orange, 10-15 parts of beautiful sweetgum fruit, 10-15 parts of kadsura pepper stem, 10-15 parts of red paeony root, 10-20 parts of Chinese angelica, 10-15 parts of szechuan lovage rhizome, 5-10 parts of dalbergia wood, 10-15 parts of corydalis tuber, 10-20 parts of kudzuvine root, 5-10 parts of liquoric root. The Chinese medicinal composition is easy to prepare; raw materials are readily-available; the bulk pharmaceuticals with different curative effects are selected according to the pathology of angina pectoris; through synergic actions of the medicaments in a formula, the Chinese medicinal composition has the effects of promoting blood circulation to dispel blood and inducing menstruation to relieve menalgia; and the Chinese medicinal composition has a good curative effect on unstable angina pectoris derived from the aged coronary heart disease.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of the coronary heart disease in aged patients unstable angina pectoris, belong to technical field of Chinese medicines.
Background technology
Angina pectoris is one of modal cardiovascular disease of old people, and along with improving constantly of living standard, old people's health is not noted taking exercise, and present stage, anginal incidence rate was the trend that rises year by year, and more and more rejuvenation.Mainly because the left ventricle cell descends and causes coronary artery luminal stenosis, arteriosclerosis to blood flow between coronary artery, cause coronary artery to reduce, slow down the blood supply of heart, make myocardial ischemia, anoxia, increase the weight of the pathological changes of heart, the small artery blood vessel is in contraction, spasticity for a long time, increased water sodium and stored up the contracting of herding of staying with peripheral vessels, increased the weight of angina pectoris, bring out the myocardial infarction river.
Angina pectoris is modal cardiovascular system diseases; unstable angina pectoris (UAP) is because unsettled atheromatous plaque secondary pathological change in arteria coronaria makes the angina pectoris of regional myocardial blood flow due to obviously descending; it is one group of clinical anginal syndrome between stable angina pectoris and acute myocardial infarction; the multiple mid-aged population of being born in; if treatment reaches not in time; serious myocardial infarction and heart source property often can occur broken dead, affect patient's life and quality of life.The medicine for the treatment of clinically unstable angina pectoris is varied, and long-term taking same medicine can produce drug resistance, and patient's the state of an illness and health is threatened.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of the aged coronary heart disease unstable angina, this medicine has good therapeutical effect to unstable angina pectoris, and drug dependence is low, and is easy to use.
The present invention is achieved by the following measures:
A kind of Chinese medicine composition for the treatment of the aged coronary heart disease unstable angina is characterized in that being comprised of the crude drug of following weight portion: Radix Astragali 20-40 part, Radix Codonopsis 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Lignum Santali Albi 5-10 part, Fructus Amomi 5-10 part, Radix Bupleuri 10-15 part, Fructus Aurantii 10-15 part, Fructus Liquidambaris 10-15 part, Caulis Piperis Kadsurae 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Chuanxiong 10-15 part, Lignum Dalbergiae Odoriferae 5-10 part, Rhizoma Corydalis 10-15 part, Radix Puerariae 10-20 part, Radix Glycyrrhizae 5-10 part.
In above-mentioned Chinese medicine composition, preferably the crude drug by following weight portion forms: 30 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 15 parts of Radix Salviae Miltiorrhizaes, 9 parts, Lignum Santali Albi, 9 parts of Fructus Amomis, 12 parts of Radix Bupleuri, 12 parts of Fructus Aurantiis, 12 parts of Fructus Liquidambaris, 12 parts of Caulis Piperis Kadsuraes, 12 parts of Radix Paeoniae Rubra, 15 parts of Radix Angelicae Sinensis, 12 parts of Rhizoma Chuanxiongs, 9 parts of Lignum Dalbergiae Odoriferaes, 12 parts of Rhizoma Corydalis, 15 parts of Radix Puerariaes, 9 parts, Radix Glycyrrhizae.
The preparation method of medicine of the present invention is: all medicine materials mixed, adds the water of the medicine that just submerges to decoct, get decoction liquor and take, take the potion decoction liquor every day, take at twice for every dose, and every minor tick 2 hours, 7 days is 1 course for the treatment of.
The inventor has obtained this formula according to great many of experiments and practical experience for many years, and in formula, each medicine material effect is as follows:
The Radix Astragali, nature and flavor are sweet, warm, return lung, spleen channel, effect with invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation, be used for that the deficiency of vital energy is weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle are difficultly burst, burst for a long time do not hold back, blood deficiency dull yellowish colored skin, interior-heat are quenched one's thirst, chronic nephritis proteinuria, diabetes.
Radix Codonopsis, nature and flavor are sweet, flat, return spleen, lung meridian, have the effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat, quench one's thirst.
Radix Salviae Miltiorrhizae, nature and flavor are bitter, be slightly cold, GUIXIN, Liver Channel, have stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, an effect of the relieving restlessness that clears away heart-fire, and is used for that menoxenia, amenorrhea dysmenorrhea, lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection are swollen and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.
Lignum Santali Albi, nature and flavor are hot, warm, return spleen, stomach, the heart, lung meridian, have the effect of circulation of qi promoting warming middle-JIAO, appetizing pain relieving, are used for QI stagnated by cold, chest pain, stomachache, stomachache lack of appetite, coronary heart diseases and angina pectoris.
Fructus Amomi, nature and flavor are hot, warm, return spleen, stomach, kidney channel, and removing dampness appetizing, warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy are used for that turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass are not hungry, Deficiency and coldness of spleen and stomach, vomiting are had loose bowels, pregnancy reactions, frequent fetal movement.
Radix Bupleuri, nature and flavor are bitter, be slightly cold, and return liver, gallbladder meridian, have the effect of reconciling superficies and interior, soothing the liver, yang invigorating, are used for cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.
Fructus Aurantii, nature and flavor are bitter, hot, acid, warm, return spleen, stomach warp, have the effect of regulating the flow of QI to ease the stomach, the stagnant relieving distension of row, are used for stopping in the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, phlegm retention, gastroptosis, proctoptosis, uterine prolapse.
Fructus Liquidambaris, nature and flavor are bitter, flat, return liver, kidney channel, have the effect that dispelling, collateral-activating, diuretic stimulate the menstrual flow, and are used for arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.
Caulis Piperis Kadsurae, nature and flavor are hot, bitter, tepor, return Liver Channel, have the effect of wind-damp dispelling, the meridian dredging, stopping numbness pain, are used for anemofrigid-damp arthralgia, arthrodynia of extremities, execute arteries and veins contracture, joint stuffiness.
Radix Paeoniae Rubra, nature and flavor are bitter, be slightly cold, and return Liver Channel, have the effect of clearing away heat and cooling blood, eliminating stasis to stop pain, are used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion tumor, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, mass in the abdomen stomachache, injury from falling down, carbuncle skin infection.
Radix Angelicae Sinensis, nature and flavor are sweet, hot, warm, return liver, the heart, spleen channel, having enriches blood invigorates blood circulation, the effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation, is used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Rhizoma Chuanxiong, nature and flavor are hot, warm, return liver, gallbladder, pericardium channel, have the effect of blood-activating and qi-promoting, wind-expelling pain-stopping, are used for menoxenia, amenorrhea dysmenorrhea, mass in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Lignum Dalbergiae Odoriferae, nature and flavor are hot, warm, return liver, spleen channel, have the effect of promoting flow of QI and blood, pain relieving, hemostasis, are used for epigastric pain, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, injury from falling down, traumatic hemorrhage.
Rhizoma Corydalis, another name Rhizoma Corydalis, corydalis tuber, rhizoma corydalis, Rhizoma Corydalis, the nature and flavor acrid, bitter, warm, return liver, spleen channel, have invigorate blood circulation, the effect of promoting the circulation of QI, pain relieving, be used for the breast side of body, epigastric pain. amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Radix Puerariae, nature and flavor are sweet, hot, cool, return spleen, stomach warp, have expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, the effect of rash, yang invigorating antidiarrheal, be used for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels, the hypertension neck pain.
Radix Glycyrrhizae, nature and flavor are sweet, flat, GUIXIN, lung, spleen, stomach warp, have the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, is used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, institute's abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The present invention prepares simply, and raw material is easy to get, and has selected the crude drug of different curative effects according to anginal pathology, synergism by each medicine in formula, played good blood circulation promoting and blood stasis dispelling, the effect of inducing menstruation to relieve menalgia, have good therapeutical effect for the coronary heart disease in aged patients unstable angina pectoris.
The specific embodiment
The present invention will be further elaborated below by specific embodiment, should be understood that, following explanation is only in order to explain the present invention, its content is not limited.
Embodiment 1
Get Radix Astragali 30g, Radix Codonopsis 15g, Radix Salviae Miltiorrhizae 15g, Lignum Santali Albi 9g, Fructus Amomi 9g, Radix Bupleuri 12g, Fructus Aurantii 12g, Fructus Liquidambaris 12g, Caulis Piperis Kadsurae 12g, Radix Paeoniae Rubra 12g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 12g, Lignum Dalbergiae Odoriferae 9g, Rhizoma Corydalis 12 g, Radix Puerariae 15g, Radix Glycyrrhizae 9g, water decocts, and takes decoction liquor.The decoction liquor instructions of taking is: take potion every day, divide and take for 2 times, child and old man take the circumstances into consideration decrement, and 7 days is 1 course for the treatment of.
Embodiment 2
Get Radix Astragali 20g, Radix Codonopsis 10g, Radix Salviae Miltiorrhizae 10g, Lignum Santali Albi 5g, Fructus Amomi 5g, Radix Bupleuri 10g, Fructus Aurantii 10g, Fructus Liquidambaris 10g, Caulis Piperis Kadsurae 10g, Radix Paeoniae Rubra 10g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 10g, Lignum Dalbergiae Odoriferae 5g, Rhizoma Corydalis 10 g, Radix Puerariae 10g, Radix Glycyrrhizae 5g, water decocts, and takes decoction liquor.The decoction liquor instructions of taking is: take potion every day, divide and take for 2 times, child and old man take the circumstances into consideration decrement, and 7 days is 1 course for the treatment of.
Embodiment 3
Get Radix Astragali 40g, Radix Codonopsis 20g, Radix Salviae Miltiorrhizae 20g, Lignum Santali Albi 10g, Fructus Amomi 10g, Radix Bupleuri 15g, Fructus Aurantii 15g, Fructus Liquidambaris 15g, Caulis Piperis Kadsurae 15g, Radix Paeoniae Rubra 15g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 15g, Lignum Dalbergiae Odoriferae 10g, Rhizoma Corydalis 15 g, Radix Puerariae 20g, Radix Glycyrrhizae 10g, water decocts, and takes decoction liquor.The decoction liquor instructions of taking is: take potion every day, divide and take for 2 times, child and old man take the circumstances into consideration decrement, and 7 days is 1 course for the treatment of.
Medicine of the present invention has the effect of blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, below by part clinical trial certificate beneficial effect of the present invention.
Clinical trial
1, patient source
The patient who suffers from unstable angina pectoris from this city collection 228 examples, patient age is all larger, and between year, the mean age is 65.7 years old at 45-80, the ill time limit is between 1-20, average life is 7.1 years, and all patients all meet cardiovascular diseases branch of Chinese Medical Association " unstable angina pectoris diagnosis and treatment suggestion ", wherein male patient's 152 examples, female patient 76 examples, patients with mild 70 examples, moderate patient's 127 examples, severe patient's 31 examples.
2, Therapeutic Method
Above-mentioned patient is equally divided into 4 groups, difference that between each group, there are no significant at aspects such as the state of an illness, sex, ages.Wherein, front 3 groups is treatment group, and the 4th group is matched group, treatment group and matched group all adopt the conventional therapies such as aspirin, calcium anticaking agents, in addition, treatment group uses respectively the embodiment of the present invention 1,2,3 medicine to treat, and matched group uses control drug to treat.Therapeutic Method is: every day taken potion by medicine of the present invention, takes at twice for every dose; Control drug is sorbitrate, every day 3 times, each 10mg.
3, criterion of therapeutical effect
Produce effects: clinical symptom relief or disappearance, electrocardiogram recovers normal level;
Effectively: clinical symptom relief, the angina pectoris attacks number of times reduces, and l-3 time/week, electrocardiogram S-T reduces, and more than rise 0.05mV, but does not return to normal level;
Invalid: clinical symptoms does not alleviate or disappears, and the angina pectoris attacks number of times is frequent, and electrocardiogram is without change.
4, therapeutic outcome
Adopt said method to treat each group patient, after treating continuously 30 days, statistics patient treatment situation, in Table 1.
Claims (2)
1. a Chinese medicine composition for the treatment of the aged coronary heart disease unstable angina, is characterized in that being comprised of the crude drug of following weight portion: Radix Astragali 20-40 part, Radix Codonopsis 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Lignum Santali Albi 5-10 part, Fructus Amomi 5-10 part, Radix Bupleuri 10-15 part, Fructus Aurantii 10-15 part, Fructus Liquidambaris 10-15 part, Caulis Piperis Kadsurae 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Chuanxiong 10-15 part, Lignum Dalbergiae Odoriferae 5-10 part, Rhizoma Corydalis 10-15 part, Radix Puerariae 10-20 part, Radix Glycyrrhizae 5-10 part.
2. the Chinese medicine composition for the treatment of aged coronary heart disease unstable angina according to claim 1, is characterized in that being comprised of the crude drug of following weight portion: 30 parts of the Radixs Astragali, 15 parts of Radix Codonopsis, 15 parts of Radix Salviae Miltiorrhizaes, 9 parts, Lignum Santali Albi, 9 parts of Fructus Amomis, 12 parts of Radix Bupleuri, 12 parts of Fructus Aurantiis, 12 parts of Fructus Liquidambaris, 12 parts of Caulis Piperis Kadsuraes, 12 parts of Radix Paeoniae Rubra, 15 parts of Radix Angelicae Sinensis, 12 parts of Rhizoma Chuanxiongs, 9 parts of Lignum Dalbergiae Odoriferaes, 12 parts of Rhizoma Corydalis, 15 parts of Radix Puerariaes, 9 parts, Radix Glycyrrhizae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100347889A CN102552793B (en) | 2012-02-16 | 2012-02-16 | Chinese medicinal composition for treating unstable angina pectoris derived from aged coronary heart disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100347889A CN102552793B (en) | 2012-02-16 | 2012-02-16 | Chinese medicinal composition for treating unstable angina pectoris derived from aged coronary heart disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102552793A CN102552793A (en) | 2012-07-11 |
| CN102552793B true CN102552793B (en) | 2013-11-13 |
Family
ID=46400247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012100347889A Expired - Fee Related CN102552793B (en) | 2012-02-16 | 2012-02-16 | Chinese medicinal composition for treating unstable angina pectoris derived from aged coronary heart disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102552793B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102755581B (en) * | 2012-07-16 | 2013-11-06 | 唐山职业技术学院 | Pharmaceutical composition for treating unstable angina pectoris |
| CN102755580B (en) * | 2012-07-16 | 2014-02-19 | 唐山职业技术学院 | Method for preparing chewable tablets of drug for treating unstable angina pectoris |
| CN104922602A (en) * | 2015-07-08 | 2015-09-23 | 于江月 | Traditional Chinese medicine for treating coronary heart disease combination dyslipidemia |
| CN106110133A (en) * | 2016-07-04 | 2016-11-16 | 满纪荣 | A kind of Chinese medicine treating unstable angina pectoris and preparation method thereof |
| CN115252691B (en) * | 2022-08-05 | 2023-05-05 | 长春中医药大学 | Traditional Chinese medicine composition for treating qi stagnation and blood stasis type coronary heart disease angina |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1127126A (en) * | 1995-01-16 | 1996-07-24 | 张吉祥 | Traditional Chinese medicine for coronary heart disease and preparing method |
| CN1309991A (en) * | 2000-11-02 | 2001-08-29 | 郑国芃 | Chinese herb medicine for treating coronary heart disease |
| CN1476849A (en) * | 2002-08-21 | 2004-02-25 | 韩海龙 | Medicine composition for promoting blood circulation and removing stasis |
| CN101675982A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Traditional Chinese medicine composition for warming heart yang and reducing phlegm and absorbing clots |
-
2012
- 2012-02-16 CN CN2012100347889A patent/CN102552793B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1127126A (en) * | 1995-01-16 | 1996-07-24 | 张吉祥 | Traditional Chinese medicine for coronary heart disease and preparing method |
| CN1309991A (en) * | 2000-11-02 | 2001-08-29 | 郑国芃 | Chinese herb medicine for treating coronary heart disease |
| CN1476849A (en) * | 2002-08-21 | 2004-02-25 | 韩海龙 | Medicine composition for promoting blood circulation and removing stasis |
| CN101675982A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Traditional Chinese medicine composition for warming heart yang and reducing phlegm and absorbing clots |
Non-Patent Citations (10)
| Title |
|---|
| 中医治疗冠心病集析;杜昱林;《中医药学刊》;20050331;第23卷(第3期);第560-563页 * |
| 中药复方治疗心绞痛的用药分析;周鲁;《时珍国医国药》;20061231;第17卷(第5期);第713-714页 * |
| 冠心病心绞痛的中西医结合治疗研究近况与展望;宋凌;《中国医药指南》;20080531;第6卷(第5期);第55页第1栏第1段，第54页第1栏第3段 * |
| 周景想.祛风药在冠心病治疗中的应用.《山东中医杂志》.2006,第25卷(第1期),第14页第1栏第2段. |
| 周鲁.中药复方治疗心绞痛的用药分析.《时珍国医国药》.2006,第17卷(第5期),第713-714页. |
| 宋凌.冠心病心绞痛的中西医结合治疗研究近况与展望.《中国医药指南》.2008,第6卷(第5期),第55页第1栏第1-13行. |
| 杜昱林.中医治疗冠心病集析.《中医药学刊》.2005,第23卷(第3期),第560-563页. |
| 治疗冠心病中药使用频率的研究分析;黄素芳;《中药新药与临床药理》;20090731;第20卷(第4期);第395-396页 * |
| 祛风药在冠心病治疗中的应用;周景想;《山东中医杂志》;20060131;第25卷(第1期);第14页第1栏第2段 * |
| 黄素芳.治疗冠心病中药使用频率的研究分析.《中药新药与临床药理》.2009,第20卷(第4期),第395-396页. |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102552793A (en) | 2012-07-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102430092B (en) | Traditional Chinese medicine composite for treating stomach cold and stomachache | |
| CN104474471A (en) | Traditional Chinese medicine composition for treating thyroid | |
| CN102552793B (en) | Chinese medicinal composition for treating unstable angina pectoris derived from aged coronary heart disease | |
| CN103071136B (en) | Traditional Chinese medicine health care product capable of regulating yin and yang balance of human bodies and preparation method of traditional Chinese medicine health care product | |
| CN102274464B (en) | Chinese medicinal composition for treating chronic hepatitis, splenauxe and cirrhosis | |
| CN104740546A (en) | Traditional Chinese medicine composition for treating gastric cancer | |
| CN103432559B (en) | Traditional Chinese medicine composition for treating spanomenorrhea and dysmenorrhea caused by blood stasis and preparation method and application thereof | |
| CN104383088A (en) | Traditional Chinese medicine composition for treating postpartum abdominal pain | |
| CN103083573B (en) | Traditional Chinese medicine used for treating alcoholic fatty liver | |
| CN103394030B (en) | Traditional Chinese medicine composition for treating depressed liver and deficient spleen | |
| CN105079676A (en) | Medicine for treating fatty liver and preparing method of medicine | |
| CN104306929A (en) | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method of traditional Chinese medicine formula | |
| CN103844164A (en) | Qi-tonifying and blood-nourishing porridge and preparation method thereof | |
| CN102688451B (en) | Chinese medicinal composition for treating alcoholic fatty liver | |
| CN103006809B (en) | Traditional Chinese medicine decoction for treating systemic lupus erythematosus | |
| CN104857454A (en) | Traditional Chinese medicine decoction for treating severe acute pancreatitis | |
| CN104524461A (en) | Medicine composition for treating myocarditis and application thereof | |
| CN104189615B (en) | Traditional Chinese medicine preparation for treating metrorrhagia and metrostaxis, and preparation method of traditional Chinese medicine preparation | |
| CN103877226B (en) | Bean curd Monopterus albus (Zuiew) gruel with nourishing liver and kidney effect and preparation method thereof | |
| CN102406915A (en) | Traditional Chinese medicine composition for treating gastroenteritis | |
| CN104940777A (en) | Electuary capable of treating liver-yang hyperactivity and spleen weakness type diarrhea during menstruation and preparation method thereof | |
| CN104857415A (en) | Glutinous rice congee taken by patients with gastric carcinoma and producing method thereof | |
| CN102406829A (en) | Chinese medicine composition for treating chest pain | |
| CN104740193A (en) | Traditional Chinese medicine composition for treating neck-shoulder muscle strain syndrome and preparation method of traditional Chinese medicine composition | |
| CN103285335A (en) | A traditional Chinese medicine preparation for the treatment of depletion of both qi and blood |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C53 | Correction of patent for invention or patent application | ||
| CB02 | Change of applicant information |
Address after: 250031 No. 25 normal road, Tianqiao District, Shandong, Ji'nan Applicant after: Chen Lin Address before: 250031 No. 25, normal road, Ji'nan, Shandong Applicant before: Chen Lin |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: LIU YUZHU Free format text: FORMER OWNER: CHEN LIN Effective date: 20131010 Owner name: CHEN LIN Effective date: 20131010 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 250031 JINAN, SHANDONG PROVINCE TO: 272000 JINING, SHANDONG PROVINCE |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20131010 Address after: Kaiyuan Road 272000 in Shandong province Jining City District No. 1 Applicant after: Liu Yuzhu Applicant after: Chen Lin Address before: 250031 No. 25 normal road, Tianqiao District, Shandong, Ji'nan Applicant before: Chen Lin |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Free format text: FORMER OWNER: CHEN LIN Effective date: 20141222 Owner name: WUPING?HONGXIN INDUSTRIAL?TECHNOLOGY DEVELOPMENT C Free format text: FORMER OWNER: LIU YUZHU Effective date: 20141222 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 272000 JINING, SHANDONG PROVINCE TO: 364300 LONGYAN, FUJIAN PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20141222 Address after: 364300 Longyan City, Fujian Province town of Pingchuan Wuping County high sand road No. 78 high dam head rental housing Patentee after: Wuping Hong Xin industrial technology development corporation, Ltd. Address before: Kaiyuan Road 272000 in Shandong province Jining City District No. 1 Patentee before: Liu Yuzhu Patentee before: Chen Lin |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131113 Termination date: 20180216 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |