CN102335377A - Formula of oral Chinese medicine for treating senile dementia - Google Patents

Formula of oral Chinese medicine for treating senile dementia Download PDF

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Publication number
CN102335377A
CN102335377A CN2011103081079A CN201110308107A CN102335377A CN 102335377 A CN102335377 A CN 102335377A CN 2011103081079 A CN2011103081079 A CN 2011103081079A CN 201110308107 A CN201110308107 A CN 201110308107A CN 102335377 A CN102335377 A CN 102335377A
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radix
parts
chinese medicine
medicine preparation
spleen
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谢培德
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Chengdu LVDI Technology Co Ltd
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Chengdu LVDI Technology Co Ltd
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Abstract

The invention provides a formula of an oral Chinese medicine for treating senile dementia. The oral Chinese medicine comprises the following components in part by weight: 9 to 15 parts of codonopsis pilosula, 12 to18 parts of astragalus, 9 to 15 parts of bighead atractylodes rhizome, 7 to 11 parts of fushen, 9 to 15 parts of spina date seed, 4 to 8 parts of thinleaf milkwort rootbark, 7 to 11 parts of Angelica sinensis, 4 to 8 parts of costustoot, 9 to 15 parts of acorus gramineus, 12 to 18 parts of sharpleaf galangal fruit, 4 to 8 parts of liquorice, and 9 to 15 parts of Chinese date. Compared with the prior art, the formula has the advantages that the Chinese medicine can treat senile dementia by differentiation of symptoms and signs aiming at the internal pathogenic factors of senile dementia, has quick response, and an obvious effect, is low in cost, does not have toxic or side effect and can address both the symptoms and root causes.

Description

A kind of Chinese medicine preparation of orally taken for curing alzheimer disease
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine preparation of orally taken for curing alzheimer disease.
Background technology
Alzheimer disease is that acquired cerebral cortex Premium Features damage comprehensively, shows as generally the going down or lose of control ability etc. of memory, judgment, sensation and motor function, speech, daily life active ability, social function, interpersonal communication, emotional responses.Slow-witted and stupid, but do not have disturbance of consciousness, can regard a syndrome as.The western medical treatment alzheimer disease adopts cholinesterase inhibitor more, but side effect such as that this type medicine has is nauseating, vomiting can bring serious burden to liver and kidney metabolism.On the traditional Chinese medical science, alzheimer disease belongs to categories such as the traditional Chinese medical science " literary composition is silly ", " forgetful ", " dementia ", " melancholia ".
Summary of the invention
The Chinese medicine preparation that the purpose of this invention is to provide a kind of orally taken for curing alzheimer disease, it is to the inherent pathogenic factor of alzheimer disease, distinguishes that disease executing control, and with strong points, curative effect is fast, and cost is low, and has no side effect, and can reach to play good prevention effect.
The traditional Chinese medical science thinks that the cause of disease of alzheimer disease behaves to person in middle and old age, and the internal organs QI and blood all loses, if inappropriate because of resting again, intemperate sexual intercourse consumes excess of four natures in foods or drugs causing damage of essence and undermines Liver and kidney; Or after the serious disease prolonged illness, or the later stage of mental diseases and apoplexy, pathogenic heat lingering, damage qi-blood-body fluid; Or be angry, or drink and be satiated with food, impairing the liver and spleen because of being worried; Or troubled thoughts pent-up with the passing of time, causes qi depression to blood stasis; Or undermine the brain mansion outward because of injuring to poison.Pathological change is old or prolonged illness, and internal organs void declines, and brains are not enough, yang imbalance, and conversion is not normal each other between the QI and blood marrow, and ascending or descending movement of vital Qi is disorderly contrary, the stagnation of phlegm blood stasis, and cause brain siddhi dysfunction and even clinical all disease peaks to rise.Viscera YIN yang-energy blood deficiency declines, vital essence can not on gather in head, deficiency of marrow-reservoir, gods lose to be supported, malfunction can not be driven body and face nine orifices outward, gradually to dull-witted generation.The pathology of primary disease is positioned at brain (marrow), and is relevant with internal organs such as the heart, kidney,liver,spleens.
The present invention adopts following technical scheme: a kind of Chinese medicine preparation of orally taken for curing alzheimer disease in weight portion, comprises following component: Radix Codonopsis 12, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12; Poria cum Radix Pini 9, Semen Ziziphi Spinosae 12, Radix Polygalae 6, Radix Angelicae Sinensis 9, the Radix Aucklandiae 6; Rhizoma Acori Graminei 12, Fructus Alpiniae Oxyphyllae 15, Radix Glycyrrhizae 6, Fructus Jujubae 12.
The Analysis on Mechanism of Chinese medicine of the present invention:
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung breath with cough, breathe hard spontaneous perspiration, feeble QI two and lose all cards." Bencao Congxin ": invigorating the spleen and replenishing QI and taste relieving thirst and restlessness.
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.There are benefiting QI for strengthening the superficies, arresting sweating to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive." Mingyi Bielu ": sweet in the mouth is nontoxic.Cure mainly strong wind at the body face, dizziness due to wind pathogen headache, the order lacrimation, expectorant water, swollen by edema due to wind pathogen knot between skin, it is full to remove spasm in the epigastrium, and cholera, tell down incessantly, blood between sharp waist umbilicus, beneficial body fluid, warming the stomach, rapid digestion of food is had a liking for food.
Poria cum Radix Pini: property is flat, sweet in the mouth, light.GUIXIN, spleen channel.Mind calming is calmed the nerves, diuretic.Control the palpitation with fear of having a guilty conscience, forgetful, insomnia, infantile convulsion, dysuria." property of medicine opinion ": main infantile convulsion, tranquilizing the mind is mended tired; Main acute pain in the epigastrium is hard full, and small intestinal is unfavorable.
Semen Ziziphi Spinosae: sour in the mouth is flat.Go into the heart, spleen, liver, gallbladder meridian.Nourishing the liver, mind calming is calmed the nerves, arresting sweating.Control restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility." book on Chinese herbal medicine converges and says ": astringing QI is calmed the nerves, and flourish muscle is supported marrow, stomach function regulating activating the spleen.
Radix Polygalae: suffering; Bitter; Slightly warm in nature.GUIXIN; Liver; Spleen; Kidney channel.Mind tranquilizing and the heart calming; Eliminate the phlegm and have one's ideas straightened out; Removing toxic substances and promoting subsidence of swelling.Cure mainly irritability; The palpitation with fear insomnia; Forgetful; Infantile convulsion; Cough with copious phlegm; The carbuncle carbuncle on the back; Breast swell and pain.Shennong's Herbal: main cough with dyspnea damaging the spleen and stomach, tonifying for the deficiency removes pathogen, sharp nine orifices, Fructus Alpiniae Oxyphyllae is intelligent, and normal hearing and eyesight is not forgotten, strong will times power.
Radix Angelicae Sinensis: warm in nature, hide sweet, hot.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Materia Medica of Decoction: Radix Angelicae Sinensis, few the moon of starting with, with its heart master blood also; It is lunar to go into foot, wraps up in blood also with its spleen; Go into the sufficient the moon of fainting, also with its blood stored in the liver.
The Radix Aucklandiae: acrid in the mouth; Bitter; Warm in nature.Return spleen; Stomach; Tripe; Lung.Promoting the circulation of QI to relieve pain; Intestinal stasis relieving in the accent." Japan hanako materia medica ": control all gas of trusted subordinate, antidiarrheal, cholera, dysentery, antiabortive, strengthening the spleen to promote digestion.It is bad to treat win, bladder cold type of pain, vomiting and regurgitation.
Rhizoma Acori Graminei: acrid in the mouth; Bitter; Slightly warm in nature.GUIXIN; Liver; Spleen channel.Waking up the patient from unconsciousness by dissipating phlegm; The removing dampness circulation of qi promoting; The sharp numbness of dispeling the wind; Reducing swelling and alleviating pain.Cure mainly calentura coma, syncope due to accumulation of phlegm, forgetful, tinnitus, deafness, abdominal distention, fasting dysentery, rheumatic arthralgia, traumatic injury, carbuncle scabies." book on Chinese herbal medicine converge with speech ": Rhizoma Acori Graminei, promoting the circulation of QI is sensible, as because of phlegm-fire two heresy be eyes afflicted with calaract, causes that gas has some setbacks, the obstructed person of key, clothes should be so.If deficiency of QI in middle-JIAO, hungry in the spirit, the gas key does not have yang-energy and moves and obstructed person for it, sees repeatly and uses decoction of ten powerful tonics, and it is extremely many to yield result, and Rhizoma Acori Graminei needn't be asked also.
Fructus Alpiniae Oxyphyllae: acrid in the mouth; Warm in nature.Return spleen; Kidney channel.The warming spleen and stopping diarrha saliva of taking the photograph; Warming the kidney reducing urination controlling nocturnal emission with astringent drugs.Be used for Deficiency and coldness of spleen and stomach, vomiting is had loose bowels, cold educating in the abdomen, mouthful many salivas, enuresis due to deficiency of the kidney, frequent micturition, seminal emission, nebulousurine." Bencao Jingshu ": the sub-core of Fructus Alpiniae Oxyphyllae, hold back with it and to take the photograph, thus control the seminal emission false leak, and dribbling urination, this all instability of kidney QI card also.
Radix Glycyrrhizae: property is flat, and sweet in the mouth is returned 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Fructus Jujubae: sweet; Temperature.Spleen; The stomach warp.Tonifying the spleen and stomach; Replenishing QI and blood; Tranquilizing mind; Transfer battalion to defend.Be used for weakness of the spleen and stomach, insufficiency of vital energy and blood, anorexia and loose stool, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI.
To the diabetes insipidus due to the deficiency of both the heart and spleen, the traditional Chinese medical science is thought excessive thinking, impairment caused by overstrain heart spleen, and heart master blood, spleen is the source of hemopoietic, heart spleen loses empty, blood failing to tonify the heart, mental derangement, deficiency of qi and blood can not on give in brain, so see dull-witted at disease; The insufficiency of blood deficiency of vital energy, so the tired think of of body is for sleeping in, shortness of breath and palpitation, the complexion look down is white; So dysfunction of the spleen in transportation is loss of appetite.
The person of choosing in the side, strengthening spleen and nourishing blood, reinforcing the heart Fructus Alpiniae Oxyphyllae, Radix Codonopsis strengthening the spleen and tonifying the lung; Radix Astragali benefiting QI for strengthening the superficies; Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI; Poria cum Radix Pini, Semen Ziziphi Spinosae, Radix Polygalae mind tranquilizing and the heart calming; Chinese angelica blood supplementing is invigorated blood circulation; Radix Aucklandiae promoting the circulation of QI to relieve pain; The Rhizoma Acori Graminei waking up the patient from unconsciousness by dissipating phlegm; Fructus Alpiniae Oxyphyllae reducing urination controlling nocturnal emission with astringent drugs; The Radix Glycyrrhizae invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription.Full side plays strengthening spleen and nourishing blood, reinforcing the heart Fructus Alpiniae Oxyphyllae, balance body negative and positive altogether.To alzheimer disease determined curative effect due to the deficiency of both the heart and spleen, prevention effect is remarkable, doublely takes stopgap measures this.
Form of Chinese drug of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
To the Chinese medicine preparation of 40 alzheimer disease patients (age 60-78) use orally taken for curing alzheimer disease of the present invention, 1 course of treatment of continued treatment (1 month), wherein 15 examples are cured fully, transference cure; 18 routine remissions, seizure frequency reduce; Invalid 7 examples, overall effective percentage reaches 82.5%, and does not have recurrence.
Instance:
The patient 1: Yuan, and the male, 69 years old, suffered from senile dementia before 4 years, obstacle appears in language function, likes repeating speaking, the cognitive disorder of had slight, amnesia, intelligence descends to some extent.The Chinese medicine preparation of treatment alzheimer disease of the present invention is used in the back, and after 1 course of treatment, above-mentioned symptom is eased, and intelligence spirit all has improvement, continues medication, and above-mentioned symptom all is effectively controlled.
The patient 2: appoint certain, and the women, 76 years old, suffer from senile dementia, often forgetful, forgetful, it is lost easily to go out, and language is dull to be repeated.Use upon somebody's introduction and take Chinese medicine preparation of the present invention, uses 1 course of treatment after, the symptom of aphasis is eased at first, can initiatively exchange with the people, the emotion recovery normally, after adhere to taking medicine always, above-mentioned symptom all disappears.
The patient 3: Wu, and the male, 80 years old, suffered from alzheimer disease 6 years, witless expression is slow in action, aphasis, to murmur to oneself is got lost easily, does not remember relatives' name clearly.Used the Chinese medicine preparation of treatment alzheimer disease of the present invention to treat afterwards, after 2 courses of treatment, aphasis obviously alleviates, and beginning normally exchanges with the people, and continued is taken medicine and controlled, and above-mentioned symptom all has alleviation.
The specific embodiment
In order to understand the present invention better, through embodiment the present invention is described below.
Embodiment 1
A kind of Chinese medicine preparation of orally taken for curing alzheimer disease in weight portion, comprises following component: Radix Codonopsis 9, and the Radix Astragali 12, the Rhizoma Atractylodis Macrocephalae 9, Poria cum Radix Pini 7, Semen Ziziphi Spinosae 9, Radix Polygalae 4, Radix Angelicae Sinensis 7, the Radix Aucklandiae 4 Rhizoma Acori Graminei 9, Fructus Alpiniae Oxyphyllae 12, Radix Glycyrrhizae 4, Fructus Jujubae 9.
Its preparation method is:
In weight portion, get Radix Codonopsis 9, the Radix Astragali 12, the Rhizoma Atractylodis Macrocephalae 9, Poria cum Radix Pini 7, Semen Ziziphi Spinosae 9, Radix Polygalae 4, Radix Angelicae Sinensis 7, the Radix Aucklandiae 4 Rhizoma Acori Graminei 9, Fructus Alpiniae Oxyphyllae 12, Radix Glycyrrhizae 4, Fructus Jujubae 9; Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag.
Embodiment 2
A kind of Chinese medicine preparation of orally taken for curing alzheimer disease in weight portion, comprises following component: Radix Codonopsis 15, and the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Poria cum Radix Pini 11, Semen Ziziphi Spinosae 15, Radix Polygalae 8, Radix Angelicae Sinensis 11, the Radix Aucklandiae 8, Rhizoma Acori Graminei 15, Fructus Alpiniae Oxyphyllae 18, Radix Glycyrrhizae 8, Fructus Jujubae 15.
Its preparation method is:
In weight portion, get Radix Codonopsis 15, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Poria cum Radix Pini 11, Semen Ziziphi Spinosae 15, Radix Polygalae 8, Radix Angelicae Sinensis 11, the Radix Aucklandiae 8, Rhizoma Acori Graminei 15, Fructus Alpiniae Oxyphyllae 18, Radix Glycyrrhizae 8, Fructus Jujubae 15; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
A kind of Chinese medicine preparation of orally taken for curing alzheimer disease in weight portion, comprises following component: Radix Codonopsis 12, and the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Poria cum Radix Pini 9, Semen Ziziphi Spinosae 12, Radix Polygalae 6, Radix Angelicae Sinensis 9, the Radix Aucklandiae 6, Rhizoma Acori Graminei 12, Fructus Alpiniae Oxyphyllae 15, Radix Glycyrrhizae 6, Fructus Jujubae 12.
Its preparation method is:
In weight portion, get Radix Codonopsis 12, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Poria cum Radix Pini 9, Semen Ziziphi Spinosae 12, Radix Polygalae 6, Radix Angelicae Sinensis 9, the Radix Aucklandiae 6, Rhizoma Acori Graminei 12, Fructus Alpiniae Oxyphyllae 15, Radix Glycyrrhizae 6, Fructus Jujubae 12; Cleaning, drying mix above-mentioned medical material, use pulverizer to pulverize and are 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing promptly gets pill.
Embodiment 4
A kind of Chinese medicine preparation of orally taken for curing alzheimer disease in weight portion, comprises following component: Radix Codonopsis 12, and the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Poria cum Radix Pini 9, Semen Ziziphi Spinosae 12, Radix Polygalae 6, Radix Angelicae Sinensis 9, the Radix Aucklandiae 6, Rhizoma Acori Graminei 12, Fructus Alpiniae Oxyphyllae 15, Radix Glycyrrhizae 6, Fructus Jujubae 12.
Its preparation method is:
In weight portion, get Radix Codonopsis 12, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Poria cum Radix Pini 9, Semen Ziziphi Spinosae 12, Radix Polygalae 6, Radix Angelicae Sinensis 9, the Radix Aucklandiae 6, Rhizoma Acori Graminei 12, Fructus Alpiniae Oxyphyllae 15, Radix Glycyrrhizae 6, Fructus Jujubae 12; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Granule is processed the 0.4g/ capsules with the capsule filler.

Claims (4)

1. the Chinese medicine preparation of an orally taken for curing alzheimer disease is characterized in that, in weight portion, comprises following component: Radix Codonopsis 9-15; Radix Astragali 12-18, Rhizoma Atractylodis Macrocephalae 9-15, Poria cum Radix Pini 7-11, Semen Ziziphi Spinosae 9-15; Radix Polygalae 4-8, Radix Angelicae Sinensis 7-11, Radix Aucklandiae 4-8, Rhizoma Acori Graminei 9-15; Fructus Alpiniae Oxyphyllae 12-18, Radix Glycyrrhizae 4-8, Fructus Jujubae 9-15.
2. Chinese medicine preparation according to claim 1 is characterized in that, in weight portion, preferably comprises following component: Radix Codonopsis 12, and the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Poria cum Radix Pini 9, Semen Ziziphi Spinosae 12, Radix Polygalae 6, Radix Angelicae Sinensis 9, the Radix Aucklandiae 6, Rhizoma Acori Graminei 12, Fructus Alpiniae Oxyphyllae 15, Radix Glycyrrhizae 6, Fructus Jujubae 12.
3. Chinese medicine preparation according to claim 1 is characterized in that, said Chinese medicine preparation adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine preparation according to claim 1 is characterized in that said Chinese medicine preparation preferably adopts solution, granule, pill and capsule.
CN2011103081079A 2011-10-12 2011-10-12 Formula of oral Chinese medicine for treating senile dementia Pending CN102335377A (en)

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Cited By (9)

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CN103536829A (en) * 2013-08-30 2014-01-29 李芝芳 Traditional Chinese medicinal prescription for invigorating intelligence and tonifying brain
CN104288646A (en) * 2014-10-31 2015-01-21 张泽 Traditional Chinese medicine preparation for improving memory
CN105412771A (en) * 2015-12-28 2016-03-23 叶德平 Chinese herbal preparation for cranial nerve rehabilitation
CN105878649A (en) * 2016-04-18 2016-08-24 易旭 Pharmaceutical composition for treating AD (Alzheimer's disease) and preparation method of pharmaceutical composition
CN106177046A (en) * 2016-08-29 2016-12-07 杨添福 A kind of nervus cognition disorder medicine based on the exploitation of Pu Lining potassium and preparation method thereof
CN106822746A (en) * 2017-03-10 2017-06-13 武汉香云盖天然香业有限公司 A kind of beneficial brain stacte and preparation method thereof
CN108785470A (en) * 2018-09-14 2018-11-13 李虎森 Clever soup herbal beverage and preparation method thereof
CN109200158A (en) * 2017-07-06 2019-01-15 厦门大学附属中山医院 A kind of combination medicine for treating Alzheimer disease
CN115844971A (en) * 2022-12-23 2023-03-28 江苏鹏鹞药业有限公司 Shiquandabu decoction for improving memory of senile dementia patients and preparation method thereof

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103536829A (en) * 2013-08-30 2014-01-29 李芝芳 Traditional Chinese medicinal prescription for invigorating intelligence and tonifying brain
CN104288646A (en) * 2014-10-31 2015-01-21 张泽 Traditional Chinese medicine preparation for improving memory
CN104288646B (en) * 2014-10-31 2017-12-26 张泽 A kind of Chinese medicine preparation for improving memory
CN105412771A (en) * 2015-12-28 2016-03-23 叶德平 Chinese herbal preparation for cranial nerve rehabilitation
CN105878649A (en) * 2016-04-18 2016-08-24 易旭 Pharmaceutical composition for treating AD (Alzheimer's disease) and preparation method of pharmaceutical composition
CN106177046A (en) * 2016-08-29 2016-12-07 杨添福 A kind of nervus cognition disorder medicine based on the exploitation of Pu Lining potassium and preparation method thereof
CN106822746A (en) * 2017-03-10 2017-06-13 武汉香云盖天然香业有限公司 A kind of beneficial brain stacte and preparation method thereof
CN109200158A (en) * 2017-07-06 2019-01-15 厦门大学附属中山医院 A kind of combination medicine for treating Alzheimer disease
CN109200158B (en) * 2017-07-06 2021-05-28 厦门大学附属中山医院 Combined medicine for treating Alzheimer disease
CN108785470A (en) * 2018-09-14 2018-11-13 李虎森 Clever soup herbal beverage and preparation method thereof
CN115844971A (en) * 2022-12-23 2023-03-28 江苏鹏鹞药业有限公司 Shiquandabu decoction for improving memory of senile dementia patients and preparation method thereof

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Application publication date: 20120201