CN102335365A - Liver-nourishing toxin-expelling powder - Google Patents
Liver-nourishing toxin-expelling powder Download PDFInfo
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- CN102335365A CN102335365A CN2011103062171A CN201110306217A CN102335365A CN 102335365 A CN102335365 A CN 102335365A CN 2011103062171 A CN2011103062171 A CN 2011103062171A CN 201110306217 A CN201110306217 A CN 201110306217A CN 102335365 A CN102335365 A CN 102335365A
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Abstract
The invention discloses liver-nourishing toxin-expelling powder. The liver-nourishing toxin-expelling powder is prepared from the following raw materials: schisandra chinensis, polygonum cuspidatum, oriental qormwood, bupleurum, skullcap, hawthorn, pseudostellaria root, yam, coix seed and raw malt in a ratio of 2:2:2:1:1:1:1:1:1:6. The formula is completely summarized in clinical practice, has innovation in traditional Chinese medicine science and traditional Chinese medicine theories, and is unique; and after 2-3 treatment courses of clinical trial, the restoration rate of ALT (aminoleucine transferase) and other liver function indexes reach 98%, HBV (hepatitis B virus) DNA (deoxyribonucleic acid) is greatly lowered or reaches normal range, and the effective rate reaches 80%, thus the liver-nourishing toxin-expelling powder is superior to other traditional Chinese medicine preparations and some western medicines.
Description
Technical field
The present invention relates to a kind of Chinese medicine of treating acute or chronic hepatitis B, be specifically related to a kind of the liver benefiting toxin expelling and loose.
Background technology
Hepatitis B is caused, is served as main and can cause a kind of infectious disease of multiple organ injury with the liver inflammatory lesion by hepatitis B virus (HBV).Primary disease is widely current in countries in the world, mainly invades child and person between twenty and fifty, and small number of patients can be converted into liver cirrhosis or hepatocarcinoma.Therefore, it has become the worldwide disease of serious threat human health, also is that China's current popular is the most extensive, the most serious a kind of infectious disease of hazardness.Hepatitis B does not have certain popular phase, all can fall ill throughout the year, but distributes belong to more.The hepatitis B sickness rate is and obviously increases trend in recent years.
Summary of the invention
The present invention has researched and developed a kind of the liver benefiting toxin expelling and has loose, and purpose is: reduce patient HBV DNA titre, general three or four purposes that reach healing the course of treatment through the method for taking Chinese medicine.
Technical solution of the present invention:
A kind of the liver benefiting toxin expelling looses, and it is characterized in that: the raw material that said the liver benefiting toxin expelling looses is Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Herba Artemisiae Scopariae, Radix Bupleuri, Radix Scutellariae, Fructus Crataegi, Radix Pseudostellariae, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus.
Said proportion of raw materials is Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Herba Artemisiae Scopariae, Radix Bupleuri, Radix Scutellariae, Fructus Crataegi, Radix Pseudostellariae, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus=2: 2: 2: 1: 1: 1: 1: 1: 1: 6.
The preparation technology that said the liver benefiting toxin expelling looses is:
1. selected above-mentioned raw materials and disinfection;
2. raw material is fried according to said ratio;
3. the pulverizer of the raw material that fries with 100 mesh sieves ground;
4. will fully mix the back through the raw material after grinding by 100～500 packing of gram/bag and cold preservations.
The instructions of taking that said the liver benefiting toxin expelling looses is: patient every day three times, and each 20 grams, the suitable decrement of child is taken after mixing with liquid with boiled water or Mel, also available decocting in water clothes.
Said the liver benefiting toxin expelling looses and can also add Radix Glycyrrhizae, Fructus Forsythiae, Radix Salviae Miltiorrhizae, triangular, Rhizoma Curcumae, Carapax Trionycis, river Squama Manis, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herba Agrimoniae except that above-mentioned raw materials.
Pharmacology analysis:
1, Fructus Schisandrae Chinensis: enzyme falls in invigorating the liver and kidney, can reduce the Glutamate pyruvate transaminase rises that carbon tetrachloride causes, hepatocyte is had certain protective role, and the lobules of liver necrotic area is dwindled.Evidence Fructus Schisandrae Chinensis kind kernel alcohol extract effect of reducing enzyme levels is obvious, and sarcocarp or kernel decoct are invalid.Fructus Schisandrae Chinensis is treated all kinds of viral hepatitis, Glutamate pyruvate transaminase rises, the thin white tongue person that lacks of body of the tongue.The Fructus Schisandrae Chinensis single is ground early, middle and late sub-service treatment chronic hepatitis, liver cirrhosis into powder.
2, Rhizoma Polygoni Cuspidati: the dehumidifying jaundice eliminating, blood circulation promoting and blood stasis dispelling, dredge the meridian passage, the dissipating blood stasis analgesic therapy suppresses virus, clearing away heat,cooling blood and removing toxin, the liver protecting promotes liver cell regeneration, repairs hepatic injury, suppresses swelling of liver cell.Rhizoma Polygoni Cuspidati treatment icterohepatitis, acute and chronic hepatitis B [HBsAg carrier], ALT, GGT increase.Chronic hepatitis is with Rhizoma Polygoni Cuspidati, normal phase of the Fructus Crataegi drink of making tea.
3, Herba Artemisiae Scopariae: treatment icterohepatitis, chronic active hepatitis, two orders are all yellow, yellowish or reddish urine, or body does not have jaundice and alanine aminotransferase and jaundice rising.Clearing away heat and promoting diuresis, function of gallbladder promoting protects the liver, and promotes bile secretion, the jaundice eliminating subcutaneous ulcer, the dampness removing antiviral has protective effect to liver, brings down a fever, the effect of jaundice eliminating subcutaneous ulcer is obvious, and the effect of the liver of dwindling spleen is arranged.Blood fat reducing, blood vessel dilating, blood pressure lowering and antibacterial action are arranged.
4, Radix Bupleuri: it is strongly fragrant to induce sweat, loose, and controls alternate attack of chill and fever, controls costa sternales pain, depression of liver-QI, liver and gall discord, incoordination between the liver and stomach, incoordination between the liver and spleen etc.Control acute jaundice, B ultrasonic shows that gallbladder wall is crude, the treatment viral hepatitis, and acute hepatitis is seen abdominal distention, costalgia, pain in the hepatic region, weak, jaundice.The merit that soothing the liver, resolving depression is arranged, expels the heat-evil, abnormal liver function [ALT rising] is joined the Radix Scutellariae hepatoprotective and is fallen enzyme.Modern pharmacological research Radix Bupleuri has effects such as antiviral, hepatic cholagogic, promotion immunity.Join the anti-hepatic injury of Fructus Forsythiae.Join the soothing the liver removing food stagnancy of Pericarpium Citri Reticulatae Viride.It is obvious to join the anti-hepatic injury of Radix Glycyrrhizae, and can make ALT decline that downright bad hepatocyte is recovered.Have anti-liver injury, jaundice eliminating, effect of reducing enzyme levels.The effect of two-ways regulation albumen is still arranged.Radix Bupleuri can be protected the damage of hepatic ischemia property, suppresses hepatocarcinoma, and anti-hepatic fibrosis improves the liver function effect.Radix Bupleuri has function of gallbladder promoting, lipotropy.That bupleurumol has is easypro, receipts, the effect of soft liver, and low dose of 6-12 gram can reach the soft liver spleen effect of relaxing.
5, Radix Scutellariae: clearing away damp-heat, purte the white, detoxifcation, hepatoprotective effect.
6, Fructus Crataegi: the dispelling the stagnated QI removing food stagnancy, the clots absorbing that reduces phlegm strengthens ferment in the stomach, and the meat that disappears is long-pending to have victory to imitate.The merit of convergence is arranged, and hepatosplenomegaly is used it, the capable stagnation of QI of strengthening the spleen and stomach.
7, Radix Pseudostellariae: supplementing QI and nourishing YIN, strengthening the spleen and tonifying the lung, QI invigorating is strong, and promoting the production of body fluid to quench thirst improves body physiological function.
8, Rhizoma Dioscoreae: supplementing QI and nourishing YIN, strengthening the spleen and tonifying the lung, the benefit of reinforcing the kidney is smart, and tonify without causing stagnation is grown and oiliness.
9, Semen Coicis: the diuretic dehumidifying, clearing away heat and discharging pus, the spleen invigorating stopping leak, it is swollen to harness the river, and coixenolide has antitumaous effect, controls digestive tract cancer.
10, Fructus Hordei Germinatus: the treatment chronic hepatitis, costalgia, hepatosplenomegaly, melancholia, acute hepatitis, chronic persistent hepatitis, liver cirrhosis, the merit of Fructus Hordei Germinatus dispersing the stagnated live-QI to relieve the stagnation of QI be first of crowd's medicine, and Fructus Hordei Germinatus is given birth to and to be used soothing the liver softening the hard mass, and removing food stagnancy is used in stir-fry.
11, Radix Glycyrrhizae: spleen reinforcing, lung moistening, detoxifcation, emergency and medicine.Antiinflammatory is arranged, antiallergic, anti-hepatic injury effect can promote the experimental animal bile secretion, and reduces bilirubin, and hypertension patient blood cholesterol is descended.
12, Fructus Forsythiae: contain oleanolic acid, ALT is descended.
Beneficial effect of the present invention:
This prescription sums up fully in clinical practice; On the traditional Chinese medical science and tcm theory, innovation is arranged, and prescription is unique, through clinical trial 2-3 after the course of treatment [be a course of treatment January]; ALT and other liver function normalization rates reach 98%; HBV DNA has and descends by a relatively large margin or reach normal range, and effective percentage reaches 80%, is superior to other Chinese medicine preparation and some Western medicine.
The specific embodiment
The liver benefiting toxin expelling preparation process of loosing:
1. selected Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Herba Artemisiae Scopariae, Radix Bupleuri, Radix Scutellariae, Fructus Crataegi, Radix Pseudostellariae, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus and disinfection.
2. according to Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Herba Artemisiae Scopariae, Radix Bupleuri, Radix Scutellariae, Fructus Crataegi, Radix Pseudostellariae, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus=2: 2: 2: 1: 1: 1: 1: 1: 1: the selected raw material of 6 proportioning, and fry.
3. the pulverizer of the raw material that fries with 100 mesh sieves ground.
4. will fully mix the back through the raw material after grinding by 100～500 packing of gram/bag and cold preservations.
Clinical effectiveness is given an example: treatment acute or chronic hepatitis B 7 examples
One, wait upon certain, the woman, 22 years old, the first visit time, on July 29th, 2009, the patient told, and suffered from 1: 4: 5 positive of hepatitis B for many years, closely looked into HBV DNA3.29E+04, was 65 times of standard.Take the liver benefiting toxin expelling and loose two courses of treatment, check on January 29th, 2010 viral level is normal, and two double 1: 5 positives are clinical cure.
Two, revive certain, the man, 50 years old, the first visit time, on December 8th, 2009, and the patient tells, and suffers from 1: 4: 5 positive of hepatitis B for many years, closely looks into HBV DNA5.49E+05, is 1098 times of standard, and B ultrasonic shows hepatic injury.Take the liver benefiting toxin expelling and loose a course of treatment, check on January 5th, 2010 liver function ALT24U/L, ALP58U/L, GGT42U/L joins the Western medicine Entecavir with clothes.Check on February 26th, 2010 liver function ALT26U/L, AST8U/L, ALP58U/L, HBV DNA5.23E+02.For normally.
Three, Yang, the man, 50 years old, the first visit time, on April 1st, 2010, the patient told, and suffered from 1: 5 positive of hepatitis B for many years, closely looked into liver function ALT441U/L, AST148U/L, the GGT105U/L effect, HBVDNA2.56E+04 is 51.2 times of standard.B ultrasonic shows hepatic injury.Taking the liver benefiting toxin expelling looses a course of treatment.Check on April 22nd, 2010 liver function GGT72U/L is surplus normal.The side is the same.December was looked into all normal HBV DNA5.00E+02 of liver function on the 22nd in 2010.Belong to arm's length standard.Top decrement informal dress.
Four, Zhu, man, 32 years old, first visit time; On October 29th, 2010, the patient tells, and suffers from 1: 3: 5 positive of hepatitis B for many years, closely looks into liver function ALT1016U/L; AST380U/L, ALT142U/L, GGT270U/L, STB 30.5 μ moI/L; Bilirubin direct 13 μ moI/L, HBV DNA9.56E+07,191200 times of standard, clothes the liver benefiting toxin expelling looses a course of treatment.On November 5th, 2010 was looked into liver function, ALT329.3U/L, and AST111.9U/L, ALP80.3U/L, GGT254U/L, STB 30.5 μ moI/L, bilirubin direct 6.1 μ moI/L are surplus normal.Former side's 15 staggering amounts.On December 13rd, 2010, look into HBV DNA5.29E+07, and 105800 times of standard explain that viral level obviously descends, and go to Shanghai to do manual work on March 8th, 2011, and it is normal to check oneself liver function, and viral level is also normal.
Five, the king so-and-so, woman, 22 years old, first visit time, on JIUYUE 5th, 2009; The patient tells, and suffers from 1: 3: 5 positive of hepatitis B for many years, closely looks into liver function ALT89U/L, and AST18U/L is surplus normal, takes diffusing 10 staggering amounts of the liver benefiting toxin expelling; Drug withdrawal one month, on February 7th, 2011 was looked into liver function ALT102, and 9U/L is surplus normal.Two double 1: 5 positives, former side adds a course of treatment.
Six, the king so-and-so, the man, 23 years old, the first visit time, on August 21st, 2010, the patient told, and suffered from 1: 3: 5 positive of hepatitis B for many years, once used interferon therapy 6 months, closely looked into liver function ALT70U/L, AST50U/L.Take the liver benefiting toxin expelling 30 staggering amounts of loosing, on October 5th, 2010 was looked into liver function ALT43U/L, AST43U/L, and GGT69U/L, HBV DNA2.17E+06,4340 times of standard, TD one month,
On November 6th, 2010 was looked into liver function ALT198U/L, AST60U/L, and GGT26U/L, former side measures January.On March 19th, 2011, look into liver function ALT99.4U/L, AST60U/L, GT26U/L.Former side measures January.
On May 21st, 2011, the patient looked into liver function ALT45.8U/L, AST51.1U/L, bilirubin direct 8.7 μ moI/L, HBV DNA3.5+05,700 times of standard.The side is with obeying two months.
On August 8th, 2011, look into liver function ALT12.6U/L, AST19.9U/L, ALP83.7U/L, GGT27U/L, surplus normal, HBV DNA1.16E+04,23.3 times of standard.Former side measures January, and restrain every days 40.
Seven, Xue so-and-so, the man, 50 years old, the first visit time, on May 2nd, 2008, the patient told, and suffered from 1: 4: 5 positive of hepatitis B for many years, occurred poor appetite, abdominal distention, discomfort such as weak recently, looked into liver function ALT76U/L, GGT171U/L.Loose for the liver benefiting toxin expelling and measure January,
On June 9th, 2008, after the patient told clothes side, body was lazy, diet takes a turn for the better.Former side's 30 staggering amounts.
On July 4th, 2008, the patient feels well, check liver function ALT33.72U/L, ST39.4U/L, LP137.9U/L, STB 12.84 μ moI/L.All in normal range.
On April 23rd, 2010, patient's drug withdrawal 1 year is felt to perfect, and being in, it is normal to do general physical work diet.Advise brew up its every day, follow up a case by regular visits to and do not see recurrence in 3 years with Herba Agrimoniae 30 grams.
Claims (4)
1. a liver benefiting toxin expelling looses, and it is characterized in that: the raw material that said the liver benefiting toxin expelling looses is Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Herba Artemisiae Scopariae, Radix Bupleuri, Radix Scutellariae, Fructus Crataegi, Radix Pseudostellariae, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus.
2. the liver benefiting toxin expelling according to claim 1 looses, and it is characterized in that: said proportion of raw materials is Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Herba Artemisiae Scopariae, Radix Bupleuri, Radix Scutellariae, Fructus Crataegi, Radix Pseudostellariae, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus=2: 2: 2: 1: 1: 1: 1: 1: 1: 6.
3. the preparation technology that the liver benefiting toxin expelling according to claim 1 and 2 looses is:
(1) raw material and disinfecting in the selected claim 1;
(2) proportioning of raw material according to claim 2 fried;
(3) pulverizer of the raw material that fries with 100 mesh sieves ground;
(4) will fully mix the back through the raw material after grinding by 100～500 packing of gram/bag and cold preservations.
4. the liver benefiting toxin expelling according to claim 1 looses, and it is characterized in that: said the liver benefiting toxin expelling looses and can also add Radix Glycyrrhizae, Fructus Forsythiae, Radix Salviae Miltiorrhizae, triangular, Rhizoma Curcumae, Carapax Trionycis, river Squama Manis, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herba Agrimoniae.
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| CN102764337A (en) * | 2012-08-20 | 2012-11-07 | 马驰 | Traditional Chinese medicine composition for curing hepatitis B |
| CN109452489A (en) * | 2018-11-14 | 2019-03-12 | 东北农业大学 | The feed addictive of fluoride protector, feed and its preparation method and application in a kind of elimination poultry body |
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| JP2011121918A (en) * | 2009-12-13 | 2011-06-23 | Shoyaku Hakko Kenkyusho:Kk | Vegetable component neutralizing antigenicity of virus |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102764337A (en) * | 2012-08-20 | 2012-11-07 | 马驰 | Traditional Chinese medicine composition for curing hepatitis B |
| CN102764337B (en) * | 2012-08-20 | 2014-04-09 | 马驰 | Traditional Chinese medicine composition for curing hepatitis B |
| CN109452489A (en) * | 2018-11-14 | 2019-03-12 | 东北农业大学 | The feed addictive of fluoride protector, feed and its preparation method and application in a kind of elimination poultry body |
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