CN102333773B - 盐皮质激素受体拮抗剂及使用方法 - Google Patents
盐皮质激素受体拮抗剂及使用方法 Download PDFInfo
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- CN102333773B CN102333773B CN201080009314.8A CN201080009314A CN102333773B CN 102333773 B CN102333773 B CN 102333773B CN 201080009314 A CN201080009314 A CN 201080009314A CN 102333773 B CN102333773 B CN 102333773B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US15957809P | 2009-03-12 | 2009-03-12 | |
| US61/159,578 | 2009-03-12 | ||
| PCT/US2010/026138 WO2010104721A1 (en) | 2009-03-12 | 2010-03-04 | Mineralocorticoid receptor antagonist and methods of use |
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| CN102333773A CN102333773A (zh) | 2012-01-25 |
| CN102333773B true CN102333773B (zh) | 2014-04-16 |
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| TWI431010B (zh) | 2007-12-19 | 2014-03-21 | Lilly Co Eli | 礦皮質素受體拮抗劑及使用方法 |
| SI3160948T1 (sl) | 2014-06-30 | 2020-06-30 | Astrazeneca Ab | Amidi benzoksazinona, kot modulatorji receptorja mineralokortikoida |
| EP3362095B1 (en) | 2015-10-13 | 2020-11-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of choroidal neovascularisation |
| ES2973248T3 (es) | 2016-07-26 | 2024-06-19 | Inst Nat Sante Rech Med | Antagonista del receptor mineralocorticoide para el tratamiento de la osteoartritis |
| WO2021180818A1 (en) | 2020-03-11 | 2021-09-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of determining whether a subject has or is at risk of having a central serous chorioretinopathy |
| WO2023031277A1 (en) | 2021-08-31 | 2023-03-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the treatment of ocular rosacea |
Citations (2)
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|---|---|---|---|---|
| CN1665780A (zh) * | 2002-06-26 | 2005-09-07 | 伊莱利利公司 | 三环甾类激素核受体调节剂 |
| CN1918151A (zh) * | 2003-12-19 | 2007-02-21 | 伊莱利利公司 | 三环甾类激素核受体调节剂 |
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| TWI431010B (zh) | 2007-12-19 | 2014-03-21 | Lilly Co Eli | 礦皮質素受體拮抗劑及使用方法 |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1665780A (zh) * | 2002-06-26 | 2005-09-07 | 伊莱利利公司 | 三环甾类激素核受体调节剂 |
| CN1918151A (zh) * | 2003-12-19 | 2007-02-21 | 伊莱利利公司 | 三环甾类激素核受体调节剂 |
Non-Patent Citations (3)
| Title |
|---|
| Philip L.Gould.Salt selection for basic drugs.《International Journal of Pharmaceutics》.1986,第33卷第201-217页. |
| Richard J.Bastin，etc.Salt Selection and Optimization Procedures for Pharmaceutical New Chemical Entities.《Organic Process Research and Development》.2000,(第4期),第427-435页. * |
| Salt selection for basic drugs;Philip L.Gould;《International Journal of Pharmaceutics》;19861231;第33卷;第201-217页 * |
Also Published As
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| MX2011009506A (es) | 2011-09-28 |
| JP5570536B2 (ja) | 2014-08-13 |
| CA2751901C (en) | 2013-08-06 |
| AU2010222902B2 (en) | 2013-04-18 |
| KR101312179B1 (ko) | 2013-09-26 |
| US20110312954A1 (en) | 2011-12-22 |
| KR20110124305A (ko) | 2011-11-16 |
| CA2751901A1 (en) | 2010-09-16 |
| US8658638B2 (en) | 2014-02-25 |
| BRPI1009257A2 (pt) | 2016-03-08 |
| EP2406252B1 (en) | 2015-05-20 |
| ES2542001T3 (es) | 2015-07-29 |
| AU2010222902A1 (en) | 2011-08-11 |
| EA201171125A1 (ru) | 2012-02-28 |
| CN102333773A (zh) | 2012-01-25 |
| WO2010104721A1 (en) | 2010-09-16 |
| EA019179B1 (ru) | 2014-01-30 |
| EP2406252A1 (en) | 2012-01-18 |
| JP2012520302A (ja) | 2012-09-06 |
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