CN102326570A - Pesticide composition containing novaluron and antibiotics compound - Google Patents
Pesticide composition containing novaluron and antibiotics compound Download PDFInfo
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- CN102326570A CN102326570A CN201110197641A CN201110197641A CN102326570A CN 102326570 A CN102326570 A CN 102326570A CN 201110197641 A CN201110197641 A CN 201110197641A CN 201110197641 A CN201110197641 A CN 201110197641A CN 102326570 A CN102326570 A CN 102326570A
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Abstract
The invention discloses pesticide composition containing novaluron and antibiotics compound, which contains an active ingredient A and an active ingredient B, wherein A is novaluron, and B is selected from any one of the following antibiotics pesticide: avermectins, emamectin benzoate and Ivermectin, and the weight percentage of the active ingredient A and the active ingredient B is: 1 to 80 percent: 1 to 20 percent. The pesticide composition can control different pests, has an obvious synergic effect, can enlarge the pesticide spectrum and has high activities to sucking insects such as aphids, plant hoppers and leafhoppers and lepidopteran insects such as diamondback moth, asparagus fern caterpillar and mite in fruit trees; due to the adoption of the pesticide composition, the use of farm chemicals can be reduced, residue of farm chemical on crops can be reduced, and the environmental pollution can be alleviated; and the pesticide composition is safe for the human beings and animals, the environmental compatibility is good, and the pests are difficult to produce the drug fastness.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the Pesticidal combination of a kind of fluorine-containing uride and antibiotics compound.
Background technology
The fluorine uride, English common name (novaluron), molecular formula: C
17H
9ClF
8N
2O
4, chemical name: (±)-N-[[[3-chloro-4-[1,1,2-three fluoro-2-(trifluoromethoxy) ethyoxyls] phenyl] ammonia] carbonyl]-2,6-difluorobenzamide.The fluorine uride belongs to novel benzoyl area kind insect growth regulator, IGR, can organize the chitin in the stage of casting off a skin in the insect growth process synthetic, casts off a skin thereby influence to palm off as, makes insect when casting off a skin, can not form new epidermis, and polypide is deformity and death.Can also regulate growing of insect, suppress molt metamorphosis, suppress the food speed of insect, have very high ovicidal activity.Main through in the insect's food-taking entering insect bodies, also can contact in the entering insect bodies.Destruction through to the growth of expense adult slowly kills off the insect pests, and this process possibly continue about several days time, and is from the not effect of insect in adult stage, comparatively safe to beneficial insect to.
AVM, English common name (abamectin), molecular formula: C
48H
72O
14(B1a) C
47H
70O
14(B1b), AVM is tagged, stomach toxicity, penetration be strong.It is a kind of macrolide disaccharide compounds, is the natural products that from edaphon, separates, and insect and mite class is had tag with stomach poison function and faint fumigation action is arranged, no systemic action.But it has very strong osmosis to blade, can kill subepidermal insect, and the longevity of residure is long.It does not kill ovum.What its mechanism of action was different with general insecticide is that it disturbs neurophysiology movable; Stimulate and discharge the r-reanal; And the r-reanal has inhibitory action to arthropodan nerve conduction; The mite class becomes, if mite and insect and larva with paralysis symptom promptly appears after medicament contacts, inertia is not got food, death after 2-4 days.Because of not causing that insect dewaters rapidly, so its lethal effect is slower.But though predatism and parasite are had direct killing effect, because of plant surface is residual few, therefore little to the damage of beneficial insect.Obvious to the root nematode effect.
First dimension salt (emamectin benzoate); Chemical name: 4 '-Biao-methylamino-4 '-the deoxidation abamectin benzoate; These article are efficient, wide spectrum, the longevity of residure are long, are good insecticidal/acaricidal agent, and its mechanism of action hinders pest movements nerve information transmission and makes the death of health paralysis.The mode of action is main action of contace poison with stomach toxicity, and crop is not had interior absorption ability, but effective infiltration of institute used crop epidermal tissue, thereby has the longer longevity of residure.To control cotton bollworm, Lepidoptera; Mite class, coleoptera and homoptera pest have high activity; And do not produce and intersect with other crops, soil with in be prone to the noresidue of degrading, free from environmental pollution; In the routine dose scope to useful insect and natural enemy, people, animal safety, can with most of combined use of pesticides.
The different cultivars composition carries out composite, is the very common method of control resistant insect.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, co-toxicity coefficient very high composite just still less.Through inventor research, find fluorine uride and AVM, ivermectin, first dimension salt can produce good synergistic effect after composite, and it is still unexposed to tie up the composite relevant report of salt about fluorine uride and AVM, ivermectin, first.
Summary of the invention
Degradation problem under the resistance generation that the long-term use of fluorine uride list agent possibly bring, the drug effect, the Pesticidal combination that the present invention proposes contains A, two kinds of active components of B, and an amount of surfactant and carrier.
Active component A is selected from the fluorine uride, and active component B is a kind of in AVM, ivermectin, the first dimension salt.
Described Pesticidal combination is characterized in that: the percentage by weight of A, two kinds of active components of B is 1%～80%: 1%～20%.
Described Pesticidal combination is characterized in that: the percentage by weight of A, two kinds of active components of B is 1%～60%: 1%～15%.
Described Pesticidal combination is characterized in that: the percentage by weight of fluorine uride and AVM is 5%～40%: 1%～10%.
Described Pesticidal combination is characterized in that: the percentage by weight of fluorine uride and ivermectin is 5%～40%: 1%～10%.
Described Pesticidal combination is characterized in that: the percentage by weight of fluorine uride and first dimension salt is 5%～40%: 1%～10%.
Usually the weight percentage of active component is 0.5～90% of a gross weight in the composition, and preferable is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the Pesticidal combination of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The surfactant that Pesticidal combination of the present invention is selected for use is known in those skilled in the art: can be selected from dispersant, wetting agent, binding agent or the antifoaming agent one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Described dispersant is selected from alkylnaphthalene sulfonate; Two (alkyl) naphthalenesulfonate formaldehyde condensation compound; Naphthalene sulfonic acid-formaldehyde condensation product; Aryl phenol polyoxyethylene succinate sulfonate; Octylphenol polyethylene oxyethylene group ether sulfate; Polycarboxylate; Lignosulfonates; The phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy; Alkyl benzene sulfonate calcium salt; The naphthalene sulfonic acid-formaldehyde condensation product sodium salt; Alkylphenol-polyethenoxy is phonetic; Aliphatic amine polyoxyethylene is phonetic; Polyoxyethylene carboxylate; During the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, tea are withered, in the soapberry powder one or more.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, the aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, melon glue, gelatin, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, PVPP, polyethylene glycol, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, triethylene glycol, the polyethylene glycol.
Described antifoaming agent is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (like capric acid) and acid amides, isooctanol, isoamyl alcohol, stearic acid, lauric acid, silicone oil, the silicone compound one or more.
Described emulsifier is selected from: agricultural newborn 500# (alkyl benzene calcium sulfonate); OP series phosphate (NPE phosphate); 600# phosphate (phenyl phenol polyoxy ethyl ether phosphate); Styrene polyoxyethylene ether ammonium sulfate salt; Alkyl biphenyl ether disulfonic acid magnesium salts; Triethanolamine salt; Farming newborn 400# (benzyl dimethyl phenol polyoxy ethyl ether); Farming newborn 600# (phenyl phenol polyoxy ethyl ether); Nongru-700 # (alkylphenol-formaldehyde resin polyoxy ethyl ether); Farming newborn 36# (phenethyl fluosite polyoxy ethyl ether); Farming newborn 1600# (phenethyl phenol polyoxy ethyl polypropylene-base ether); Ethylene oxide-propylene oxide block copolymer; OP series (NPE); By series (castor oil polyoxyethylene ether); Farming newborn 33# (alkylaryl polyoxyethylene polyoxypropylene ether); Farming newborn 34# (alkylaryl polyoxyethylene poly-oxygen propylene aether); Sapn series (sorbitan monostearate); Tween series (sorbitan fatty acid ester APEO); In the AEO series (AEO) one or more.
Described solvent is selected from: N, dinethylformamide, 3-methyl cyclohexanol ketenes, N-octylpyrrolidone, N-pyrrolidones, toluene, propyl alcohol, cyclohexanone, acetone, methyl alcohol, ethanol, butanols, EGME, butyl ether, ethyl acetate, vegetable oil, acetonitrile one or more.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, adhesive, the antifoaming agent etc. one or more again.
Pesticidal combination of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion.
Comprise following constituent content when composition is processed wetting powder: fluorine uride 1～80%, active component B1～20%, dispersant 5～10%, wetting agent 2～10%, filler add to 100%.
Active component fluorine uride, active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
Comprise following constituent content when composition is processed water dispersible granules: active component fluorine uride 1～80%, active component B1～20%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler add to 100%.
Active component fluorine uride, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that article are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
Comprise following constituent content when composition is processed suspending agent: active component fluorine uride 1～50%, active component B1～10%, dispersant 2～10%, wetting agent 2～10%, antifoaming agent 0.1～1%, binding agent 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, antifoaming agent, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear; Add active component fluorine uride, active component B; Ball milling is 2～3 hours in ball mill; Make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
Comprise when composition is processed microemulsion: fluorine uride 1～50%, active component B 1～10%, solvent 3～30%, emulsifier 3～15%, antifreeze 1～4%, antifoaming agent 0.01～1%, thickener 0.2～2%, deionized water add to 100%.
Former medicine is dissolved in the agitated reactor that solvent and cosolvent are housed; Give intense mixing and homogenize after joining anion emulsifier, nonionic emulsifier and stabilizing agent, antifreeze, water in the agitated reactor that above-mentioned solution is housed, obtain the as clear as crystal microemulsion product of the present invention of outward appearance at last.
The said Herbicidal combinations that contains fluorine uride and antibiotics comprises when it is characterized in that processing aqueous emulsion: fluorine uride 1～50%, active component B 1～10%, solvent 3～30%, emulsifier 1～8%, antifreeze 1～4%, antifoaming agent 0.01～1%, thickener 0.2～2%, deionized water add to 100%.
Fluorine uride, antibiotics, solvent, emulsifier in the prescription are added together, make and be dissolved into even oil phase; Water, antifreeze, antifoaming agent, thickener are mixed, become the homogeneous water; Under high-speed stirred, water is added oil phase or oil phase is added water, make aqueous emulsion product of the present invention behind the good dispersion.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
The invention has the advantages that: after (1) fluorine uride and antibiotic insecticide are composite, have notable synergistic and lasting effect; (2) enlarged insecticidal spectrum, to aphid, rice fulgorid, rice leaf roller, diptera, coleoptera, lepidoptera pest such as diamond-back moth, beet armyworm etc., and multiple pest mite classes such as fruit tree, cotton etc. all have greater activity; (3) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution; (4), insect good to person poultry safety, Environmental compatibility is difficult for developing immunity to drugs.
Embodiment
The present invention is explained further that the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
Instance one 45% fluorine uride AVM wetting powder
Fluorine uride 30%, AVM 15%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, spaonin powder 5%, white carbon 2%, diatomite add to 100%, make 45% fluorine uride AVM wetting powder by conventional production process.
Instance 2 48% fluorine uride AVM wetting powders
Fluorine uride 40%, AVM 8%, lignosulfonates 7%, soapberry powder 3%, white carbon 4%, kaolin adds to 100%, makes 48% fluorine uride AVM wetting powder by conventional production process.
Instance 3 22% fluorine uride AVM water dispersible granules
Fluorine uride 20%, AVM 2%, alkylnaphthalene sulfonate 6%, draw back powder 4%, urea 2%, starch 10%, bentonite and add to 100%, mixed 22% fluorine uride AVM water dispersible granules.
Instance 4 40% fluorine uride AVM water dispersible granules
Fluorine uride 32%, AVM 8%, alkyl benzene sulfonate calcium salt 8%, lauryl sodium sulfate 6%, ammonium sulfate 2%, bentonite add to 100%, the mixed 40% fluorine uride AVM water dispersible granules that gets.
Instance 5 15% fluorine uride AVM suspending agents
Fluorine uride 5%, AVM 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 10%, soapberry powder 5%, silicone oil 0.3%, polyvinylpyrrolidone 0.4%, glycerine 0.5%, deionized water add to 100%, the mixed 15% fluorine uride AVM suspending agent that gets.
Instance 6 24% fluorine uride AVM suspending agents
Fluorine uride 16%, AVM 8%, polycarboxylate 8%, spaonin powder 5%, isooctanol 0.5%, melon glue 0.3%, ethylene glycol 2%, deionized water add to 100%, the mixed 24% fluorine uride AVM suspending agent that gets.
Instance 7 25% fluorine uride abamectin aqueous emulsions
Fluorine uride 20%, AVM 5%, N-pyrrolidones 6%, agricultural newborn 1600#8%, ethylene glycol 2%, PAA 1.3%, silicone oil 0.5%, water is mended to 100%, makes 25% fluorine uride abamectin aqueous emulsion.
Instance 8 50% fluorine uride abamectin aqueous emulsions
Fluorine uride 40%, AVM 10%, acetone 4%, vegetable oil 4%, OP series 5%, propane diols 2.8%, phenolic resins 1.2%, silicone 0.3%, water is mended to 100%, makes 50% fluorine uride abamectin aqueous emulsion.
Instance 9 30% fluorine uride avermectin micro-emulsions
Fluorine uride 24%, AVM 6%, EGME 5%, acetone 6%, Nongru-700 #8%, methylcellulose 1%, glycerine 2.3%, silicone compound 0.1%, water supply 100%, make 30% fluorine uride avermectin micro-emulsion.
Instance ten 36% fluorine uride avermectin micro-emulsions
Fluorine uride 30%, AVM 6%, N, dinethylformamide 7%, toluene 5%, tween series 6%, silicone oil 0.2%, Magnesiumaluminumsilicate 0.9%, ethylene glycol 2%, water supplies 100%, makes 36% fluorine uride avermectin micro-emulsion.
Instance ten one 32% fluorine uride first dimension salt wetting powder
Fluorine uride 30%, first dimension salt 2%, lignosulfonates 5%, lauryl sodium sulfate 5%, wetting and penetrating agent F 2%, attapulgite add to 100%, make 32% fluorine uride first dimension salt wetting powder by conventional production process.
Instance ten two 42% fluorine uride first dimension salt wetting powder
Fluorine uride 40%, first dimension salt 2%, draw back powder 3%, alkylnaphthalene sulfonate 4%, white carbon 2%, kaolin and add to 100%, make 42% fluorine uride first dimension salt wetting powder by conventional production process.
Instance ten three 30% fluorine uride emamectin benzoate water dispersible granules
Fluorine uride 25%, first dimension salt 5%, neopelex 4%, alkyl benzene sulfonate calcium salt 7%, urea 1%, sodium carbonate 3%, sodium phosphate trimer 0.5%, diatomite add to 100%, make 30% fluorine uride emamectin benzoate water dispersible granule by conventional production process.
Instance ten four 44% fluorine uride emamectin benzoate water dispersible granules
Add to 100% by fluorine uride 40%, first dimension salt 4%, neopelex 5%, alkylnaphthalene sulfonate 6%, urea 1%, ammonium sulfate 4%, gum Arabic 0.3%, kaolin, make 44% fluorine uride emamectin benzoate water dispersible granule by conventional production process.
The agent of instance ten five 2% fluorine uride first dimension salt suspension
Fluorine uride 1%, first dimension salt 1%, polycarboxylate 10%, lauryl sodium sulfate 6%, lauric acid 0.5%, xanthans 1%, deionized water adds to 100%, and is mixed that 2% fluorine uride first is tieed up the salt suspension agent.
The agent of instance ten six 11% fluorine uride first dimension salt suspension
Fluorine uride 10%, first dimension salt 1%, lignosulfonates 5%, tea are withered 4%, gum Arabic 0.3%, silicone oil 0.5%, ethylene glycol 0.6%, and deionized water adds to 100%, mixed 11% fluorine uride first dimension salt suspension agent.
Instance ten seven 45% fluorine uride emamectin benzoate water emulsions
Fluorine uride 42%, first dimension salt 3%, 3-methyl cyclohexanol ketenes 4%, OP series 7%, propyl alcohol 3%, ethylene glycol 2.8%, CMC 1.3%, C
8～10Aliphatic alcohols 0.2%, water is mended to 100%, makes 45% fluorine uride emamectin benzoate water emulsion.
Instance ten eight 10% fluorine uride emamectin benzoate water emulsions
Fluorine uride 7%, first dimension salt 3%, N-pyrrolidones 5%, EGME 3%, agricultural newborn 33#8%, glycerine 2.5%, Magnesiumaluminumsilicate 1.2%, silicone compound 0.3%, water is mended to 100%, makes 10% fluorine uride emamectin benzoate water emulsion.
Instance ten nine 20% fluorine uride first dimension salt microemulsion
Fluorine uride 18%, first dimension salt 2%, cyclohexanone 6%, toluene 4%, 600# phosphate 6%, polyethylene glycol 1.9%, water supplies 100%, makes 20% fluorine uride first dimension salt microemulsion.Instance two ten 45% fluorine uride first dimension salt microemulsion
Fluorine uride 40%, first dimension salt 5%, acetone 4%, N-octylpyrrolidone 5%, styrene polyoxyethylene ether ammonium sulfate salt 6%, silicone oil 0.4%, xanthans 1.1%, glycerine 3%, water supplies 100%, makes 45% fluorine uride first dimension salt microemulsion.
Instance two ten one 45% fluorine uride ivermectin wetting powders
Fluorine uride 40%, ivermectin 5%, alkyl benzene sulfonate calcium salt 6%, wetting and penetrating agent F3%, bentonite add to 100%, make 45% fluorine uride ivermectin wetting powder by conventional production process.
Instance two ten two 53% fluorine uride ivermectin wetting powders
Fluorine uride 50%, ivermectin 3%, lignosulfonates 4%, lauryl sodium sulfate 4%, white carbon 5%, diatomite add to 100%, make 53% fluorine uride ivermectin wetting powder by conventional production process.
Instance two ten three 16% fluorine uride ivermectin water dispersible granules
Fluorine uride 15%, ivermectin 1%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 8%, spaonin powder 2%, starch 10%, ammonium sulfate 1%, polyvinylpyrrolidone 0.4%, bentonite add to 100%, make 16% fluorine uride ivermectin water dispersible granules by conventional production process.
Instance two ten four 25% fluorine uride ivermectin water dispersible granules
Fluorine uride 20%, ivermectin 5%, polycarboxylate 8%, neopelex 6%, spaonin powder 2%, sodium carbonate 5%, starch 15%, diatomite add to 100%, the mixed 25% fluorine uride ivermectin water dispersible granules that gets.
Instance two ten five 9% fluorine uride ivermectin suspending agents
Fluorine uride 8%, ivermectin 1%, alkylnaphthalene sulfonate 6%, lauryl sodium sulfate 6%, C
8～10Aliphatic alcohols 0.3%, sodium phosphate trimer 0.5%, deionized water adds to 100%, the mixed 9% fluorine uride ivermectin suspending agent that gets.
Instance two ten six 18% fluorine uride ivermectin suspending agents
Fluorine uride 15%, ivermectin 3%, alkyl benzene sulfonate calcium salt 6%, draw back powder 4%, silicone compound 0.6%, polyvinyl alcohol 0.5%, glycerine 2%, deionized water and add to 100%, mixed 18% fluorine uride ivermectin suspending agent.
Embodiment two ten seven 15% fluorine uride ivermectin aqueous emulsions
Fluorine uride 14%, ivermectin 1%, N, dinethylformamide 3%, tween series 6%, vegetable oil 4%, propane diols 2%, polyvinyl alcohol 1.2%, silicone compound 0.2%, water is mended to 100%, makes 15% fluorine uride ivermectin aqueous emulsion.
Embodiment two ten eight 32% fluorine uride ivermectin aqueous emulsions
Fluorine uride 30%, ivermectin 2%, toluene 4%, cyclohexanone 4%, 600# phosphate 5%, ethylene glycol 2.3%, xanthans 1%, silicone oil 0.3%, water is mended to 100%, makes 32% fluorine uride ivermectin aqueous emulsion.
Embodiment two ten nine 18% fluorine uride ivermectin micro emulsions
Fluorine uride 15%, ivermectin 3%, ethyl acetate 3%, N-pyrrolidones 7%, agricultural newborn 34#7%, triethylene glycol 2.1%, water supplies 100%, makes 18% fluorine uride ivermectin micro emulsion.
Embodiment three ten 48% fluorine uride ivermectin micro emulsions
Fluorine uride 45%, ivermectin 3%, toluene 4%, 3-methyl cyclohexanol ketenes 5%, agricultural newborn 500#6%, C
8～10Aliphatic alcohols 0.4%, hydroxyethylcellulose 0.7%, diethylene glycol (DEG) 2.6%, water supplies 100%, makes 48% fluorine uride ivermectin micro emulsion.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC＜80 are antagonism, and 80≤CTC≤120 are summation action, and CTC＞120 are synergistic effect, on this basis, carry out field trial again.
Test method: respectively the mother liquor of each mixed agent of fluorine uride effective active composition B is diluted to five series concentration during test, places beaker subsequent use respectively.Adopt and to soak the method that connects worm behind the leaf earlier, the blade of the same size that does not contact any medicament is soaked taking-up behind the 5s, dries naturally in the soup that configures, put into insect box; Connect then and supply examination 3 instar larvaes, under 25 ℃ of conditions, raise, every processing repeats for 3 times; Every to repeat used examination borer population be 20, establishes blank simultaneously, checks dead borer population in 72h; Calculate lethality and corrected mortality, try to achieve virulence regression equation and calculate LC
50Value.If the contrast lethality then is regarded as invalid test greater than 10%.Computing formula is following:
To supply examination insect corrected mortality to be converted into probit value (y), concentration of treatment (μ g/ml) converts logarithm value (x) to, draws virulence regression equation with method of least squares, and calculates the value of every kind of medicament thus.Calculate co-toxicity coefficient CTC according to the abundant equation of Sun Yun.Computing formula is (with the fluorine uride is the standard medicament, and its toxicity index is 100) as follows:
TI * the P of theoretical toxicity index (TTI)=fluorine uride of M
The fluorine urideTI * P of+effective active composition B
Effective active composition B
In the formula: M is the mixture of different proportionings
P
Effective active composition BBe effective active composition B shared ratio in composition
P
The fluorine urideBe fluorine uride shared ratio in composition
A is selected from the fluorine uride;
B is selected from following any one insecticide: AVM, ivermectin, first dimension salt.
Application implementation example two
Supply the examination insect: rice-stem borer.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective lethal concentration scope of confirming fluorine uride, the former medicine of B and the two different proportioning mixture through preliminary experiment.
Toxicity test result one
The different proportionings with AVM of table 1 fluorine uride are to the toxicity test of rice-stem borer
Can know by table 1; The proportioning 80: 1 of fluorine uride and abamectin compounded control rice-stem borer, to 1: 20 o'clock, co-toxicity coefficient is all greater than 120, explains that both were mixed in the scope at 80: 1 to 1: 20 all to show synergistic effect; Especially when the proportioning of fluorine uride and AVM during at 10: 1 to 1: 4; Synergistic effect is more obviously outstanding, so when the fluorine uride: AVM all had synergistic function between 1: 20 the time at 80: 1.
Toxicity test result two
Table 2 fluorine uride and the toxicity test of the different proportionings of first dimension salt to rice-stem borer
Can know by table 2; The proportioning 80: 1 of the composite control of fluorine uride and first dimension salt rice-stem borer, to 1: 20 o'clock, co-toxicity coefficient is all greater than 120, explain both; Be mixed in 80: 1 to 1: 20 scopes and all show synergistic effect; Especially when fluorine uride and first dimension salt got proportioning at 10: 1 to 1: 4, synergistic effect was more obviously outstanding, and thus when the fluorine uride: first is tieed up salt all had synergistic function between 1: 20 the time at 80: 1.
Toxicity test result three
The different proportionings with ivermectin of table 3 fluorine uride are to the toxicity test of rice-stem borer
Can know by table 1; The proportioning 80: 1 of the composite control of fluorine uride and ivermectin rice-stem borer, to 1: 20 o'clock; Co-toxicity coefficient is all greater than 120, explains that both were mixed in the scope at 80: 1 to 1: 20 all to show synergistic effect, especially when the proportioning of fluorine uride and ivermectin during at 10: 1 to 1: 4; Synergistic effect is more obviously outstanding, and thus when the fluorine uride: ivermectin all had synergistic function between 1: 20 the time at 80: 1.
Application implementation example trifluoro uride and the ivermectin and the composite control citrus red mite test of pesticide effectiveness thereof
This EE is in Liquan County, Xianyang, Shanxi province city, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 10% fluorine uride missible oil (commercial), 5% ivermectin missible oil (commercial).
Investigation citrus red mite insect pest index before the medicine in the their early stage dispenser, was investigated the insect pest indexes in 24 hours, 72 hours after the dispenser and is calculated preventive effect.Experimental result is as follows:
Table 3 fluorine uride, ivermectin and the composite control citrus red mite test of pesticide effectiveness thereof
Can find out that by table 3 can effectively prevent and treat citrus red mite after fluorine uride and ivermectin are composite, control efficiency all is superior to the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application implementation example tetrafluoro uride and the first dimension salt and the composite control rice-stem borer test of pesticide effectiveness thereof
This EE is paddy field in suburb, Honghu City, Hubei Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 10% fluorine uride missible oil (commercial), 1% first dimension salt missible oil (commercial).
Investigation rice-stem borer insect pest index before the medicine in the their early stage dispenser, was investigated the insect pest indexes in 24 hours, 72 hours after the dispenser and is calculated preventive effect.Experimental result is as follows:
Table 4 fluorine uride, first dimension salt and the composite control rice-stem borer test of pesticide effectiveness thereof
Can find out that by table 4 can effectively prevent and treat rice-stem borer after fluorine uride and first dimension salt are composite, control efficiency all is superior to the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects, and to rice hoppers, paddy stem borer, rice leaf roller have preventive effect preferably.Application implementation example five fluorine urides and the AVM and the composite control wild cabbage diamond-back moth test of pesticide effectiveness thereof
This EE is Shuozhou City vegetables main producing region in the Shanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 10% fluorine uride missible oil (commercial), 1.8% abamectin emulsifiable concentrate (commercial).
Investigation wild cabbage diamond-back moth insect pest index in the their early stage dispenser, was investigated the insect pest indexes in 24 hours, 72 hours after the dispenser and is calculated preventive effect before the medicine.Experimental result is as follows:
Table 3 fluorine uride, AVM and the composite control wild cabbage diamond-back moth test of pesticide effectiveness thereof
Can find out by table 3, the fluorine uride and abamectin compounded after can effectively prevent and treat the wild cabbage diamond-back moth, control efficiency all is superior to the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects, and vegetables cabbage caterpillar, beet armyworm, prodenia litura, aphid etc. are all had preventive effect preferably.
Claims (8)
1. the Pesticidal combination of fluorine-containing uride and antibiotics compound; Comprise effective active component, auxiliary agent and filler; It is characterized in that: A, B percentage by weight are 1%～80%: 1%～20%; Described A is selected from the fluorine uride, and B is selected from a kind of in AVM, ivermectin, the first dimension salt.
2. Pesticidal combination according to claim 1 is characterized in that: the percentage by weight of A, two kinds of active components of B is 1%～60%: 1%～15%.
3. Pesticidal combination according to claim 2 is characterized in that: the percentage by weight of fluorine uride and AVM is 5%～40%: 1%～10%.
4. Pesticidal combination according to claim 2 is characterized in that: the percentage by weight of fluorine uride and ivermectin is 5%～40%: 1%～10%.
5. Pesticidal combination according to claim 2 is characterized in that: the percentage by weight of fluorine uride and first dimension salt is 5%～40%: 1%～10%.
6. Pesticidal combination according to claim 1 is characterized in that: composition is processed wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion.
7. Pesticidal combination according to claim 1 is in the application of control crop pests and pest mite.
8. application according to claim 7 is characterized in that: Pesticidal combination is used to prevent and treat diptera, coleoptera, lepidoptera pest and the pest mite on paddy rice, vegetables, cotton, the fruit.
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