CN102318821B - Special meal nutritional food applicable to males preparing childbearing - Google Patents
Special meal nutritional food applicable to males preparing childbearing Download PDFInfo
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- CN102318821B CN102318821B CN2011102422080A CN201110242208A CN102318821B CN 102318821 B CN102318821 B CN 102318821B CN 2011102422080 A CN2011102422080 A CN 2011102422080A CN 201110242208 A CN201110242208 A CN 201110242208A CN 102318821 B CN102318821 B CN 102318821B
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Abstract
The invention relates to a special meal nutritional food applicable to males preparing to have a baby, which contains lycopene, acanthopanax extractive, vitamine E, vitamine C, vitamine B6, vitamine B12, folic acid, beta-carotene, selenium-contained compound and zinc-contained compound, wherein all the raw materials have the weight ratios of: 2-30mg of lycopene; 100-500 mg of acanthopanax extractive; 10-100mg of vitamine E; 50-300mg of vitamine C; 0.5-8mg of vitamine B6; 1.5-8ug of vitamine B12; 100-400ug of folic acid; 250-1250mug RE of beta-carotene; 20-100ug of selenium-contained compound; and 5-20mg of zinc-contained compound. The special meal nutritional food applicable to the males preparing to have a baby is the novel and comprehensive nutritional food, the male physiological function can be totally improved, the free radical is cleared, and the immunity is improved.
Description
Technical field
The invention belongs to nutritious health caring food technology field, relate to a kind of special meal nutritional food that the man who prepares fertility provides natural active matter and nutrient to replenish that is in particular.
Background technology
The meaning of preparing before the male fertility is the same great with the meaning of the pregnant front preparation of women, inaccurate father is except checking the disease that oneself has or not the impact fertility, also to select health diet, alleviate self pressure and set up good habits and customs, as much as possible improve wife's the probability of becoming pregnant.
Fast development along with national economy, people's rhythm of life is more and more faster, make the man of the cause that much is in, family's core often be in the state of inferior health, and then affect man's healthy reproduction, cause the reason of this state to be mainly manifested in: 1, unhealthy emotion, many men are in operating pressure or the domestic troubles for a long time, spirit is in high-pressure, melancholy oppressive state, can cause nervous system and the internal system dysfunction of body, testicular spermatogenic function is bad, affects the quality of sperm.2, unreasonable diet, the most man of modern society does not note replenishing of nutrition and collocation, partial eclipse meat or fish and fried food, and vegetables, fruit eat lessly, so just be easy to cause the shortage of many vitamins and mineral matter, and then the impact comprise many body functions of reproductive function, thereby can have influence on inevitably the next generation.3, bad life habits because working environment, so that many men stay up late for a long time, sitting, will face many dinner parties simultaneously, for a long time in a large number or excessive consumption of alcohol, smoking, drinks coffee, strong tea, eats and have irritating food.Excessive drinking and smoking are the formidable enemies of sperm.Alcohol can cause the gonad function to reduce, and makes chromosome abnormality in the sperm, thereby causes fetal anomaly or depauperation.Drink for a long time or heavy drinking can cause chronic or acute alcoholism, make 70% cacospermia or LOM.Nicotine has the effect that reduces sex hormone and Killing Sperm, the man who inhales 30 cigarettes every day, and the survival rate of its sperm only has 49%, and rate of teratosperm increases simultaneously.Strong tea disturbs the absorption of iron, causes the man to keep body immunity and the decline of antineoplastic ability.4, other factors is such as some environmental factors such as medicine, rays.The male sex who is in breeding time often uses busulfan, the furans in sedative, antineoplastic, the chemicals, and amcinonide can cause sperm growth disorder, chromosome damage.The long-term object for appreciation computer of some men, make a phone call with mobile phone, because the radiation meeting that these communications services produce has a huge impact sperm, if long-term use can reduce sperm quantity or cause teratospermia.A large amount of radiation exposures also can cause the distortion of Human Sperm Chromosome.
In addition, the mistaken ideas that many people are very large to the cognitive presence of nutrient knowledge, as think to have a meal more and eat fruit more and just can not lack vitamin and mineral matter; The kind of replenishing vitamins and mineral matter is The more the better; External nutrient prime replenisher is good, is fit to us and eats etc.Investigation according to the Ministry of Public Health and State Statistics Bureau is found, China resident and the Hesperian common people are variant on diet, they are as main take animal food, and the resident of our country is as main take plant food, dietary structure by China is determined just, we can not obtain daily required vitamin and mineral matter by diet fully, and the nutrition that generally lacks have Cobastab
1, Cobastab
6, vitamin C, zinc, selenium etc.
In allegro modern society, the man who is in cause, family's core necessarily can not ignore nutrition when preparing fertility.Because the cycle that sperm produces needed about 10 weeks, so the husband should begin to adopt Nutrition Project at the conceived first trimester of wife.Studies show that, husband's nutrition intake can affect sperm, affects the most at last fetus.Picked-up vitamin and mineral matter cross that I haven't seen you for ages increases the genetic damage of sperm, reduce man's sperm quality and vigor, and the probability that can make baby's birth defect and suffer from hereditary disease increases.
Therefore, diet structure and physilogical characteristics man for the child-bearing period man want a healthy baby, simultaneously also be healthy for friend man, when emphasizing to strike a proper balance between work and rest, changing bad life habits, to various nutrients carry out targetedly scientific and reasonable additional be very necessary.
At present, although many nutritional drugs are arranged on the market, but great majority all are vitamin, mineral matter class and tonifying kidney and strengthening yang medicine that some are simple, more or less all exist and form unreasonable, the unreasonable and irrational problem of using dosage of collocation, also not for the actual conditions of preparing the fertility man, so can not nurse one's health all sidedly man's physiological function, thereby be difficult to the effect that reaches desirable.
Wilsonii is again cortex acanthopanacis, thorn bent stick (Northeast China), and Araliaceae mainly is distributed in China northeast and North China.Root skin wines used as antirheumatic, strengthening the bones and muscles, the slender acanthopanax bark spirit processed of steeping in wine (or it is loose to make cortex acanthopanacis).The main composition of siberian Ginseng P.E is Eleutheroside B, eleutheroside E etc., have anti-oxidant, antifatigue, antitumor, promote that male reproductive system is healthy, balance the body is metabolic, improve immunity of organisms, strengthen human body to the effect of the resistance of various diseases, be acknowledged as a kind of typical strong class medicine.Manyprickle acanthopanax general saponin energy hemangiectasis lowers the oxygen demand of organizing, and removes free radical, improves the content of superoxide dismutase.Find that in the impact of manyprickle acanthopanax general saponin Ascorbic Acid system generation hydroxy radical the effect that hydroxy radical generates that suppresses is arranged under finite concentration.Siberian Ginseng P.E is multiplex, poor appetite weak in the insufficiency of both the spleen and the kindey, body void, soreness of waist and knee joint, insomnia and dreamful sleep at present.
Lycopene is a kind of in the carotenoid, is a kind of natural colouring matter contained in the plant.Mainly be present in the ripening fruits of plant of Solanaceae tomato.The powerful antioxidant that present occurring in nature is found, can singlet-oxygen quenching and eliminate peroxylradicals; This effect outclass other carotenoid and vitamin E, its singlet-oxygen quenching speed constant is 100 times of vitamin E, also has anticancer effect, report, lycopene not only can prevent to treat prostate cancer, can effectively preventing because of aging, the various diseases that immunity degradation causes.
Summary of the invention
Problem to be solved by this invention is that a kind of special meal nutritional food that is suitable for the man for preparing to give birth to is provided for above-mentioned prior art, its siberian Ginseng P.E that contains, lycopene and vitamin and mineral matter, can nurse one's health male sex's physiological function comprehensively, play free radical, the oxidation resistant effect of removing.
[0012]The present invention is that the solution that problem adopts of the above-mentioned proposition of solution is: be applicable to the man's for preparing to give birth to special meal nutritional food, it is characterized in that its material composition includes lycopene, siberian Ginseng P.E, vitamin E, vitamin C, Cobastab
6, Cobastab
12, folic acid, beta carotene, selenium-containing compound and zinc compound, the shared weight proportion of each material composition is:
Lycopene 2-30mg siberian Ginseng P.E 100-500mg
Vitamin E 10-100mg vitamin C 50-300mg
Cobastab
60.5-8mg Cobastab
121.5-8 μ g
Folic acid 100-400 μ g beta carotene 250-1250 μ gRE
Se content 20-100 μ g zinc content 5-20mg
Press such scheme, described special meal nutritional food also includes the material composition of following weight proportion:
Grape-kernel oil 100-1000mg soybean lecithin 30-100mg
Press such scheme, described special meal nutritional food also includes the material composition of following weight proportion:
Grape seed extract 50-200mg
Press such scheme, described special meal nutritional food also includes the material composition of following weight proportion:
Glutathione 1-10mg citrus extracts 5-20mg
L-arginine 5-25mg
The below introduces the characteristic of each material composition of the present invention in detail:
Siberian Ginseng P.E: have anti-oxidant, antifatigue, antitumor, promote that male reproductive system is healthy, balance the body is metabolic, improve immunity of organisms, strengthen human body to the resistance of various diseases, be a kind of typical strong class medicine.Be used for that the insufficiency of both the spleen and the kindey, body void are weak, poor appetite, soreness of waist and knee joint, insomnia and dreamful sleep.
Lycopene: have anti-oxidant, inhibitory mutagenesis, Cell differentiation inducing activity, enhancing immunity, reduce nucleic acid damaging, reduce angiocardiopathy, pre-anti-cancer and strengthen the plurality of health care functions such as GJIC, the application in health food will more and more be taken seriously.
Grape seed extract: be the new and effective natural material that can not synthesize in a kind of human body that from grape pip, extracts, anti-oxidant, the strongest material of removing free radical ability that present occurring in nature is found, its antioxidation activity is 50 times, ascorbic 20 times of vitamin E, it can effectively remove unnecessary free radical in the human body, has the superpower effect that delays senility and strengthen immunity.Anti-oxidant, antiallergy, antifatigue are built up health, are improved sub-health state and delay senility, improve the symptoms such as irritated irritability, dizzy weak, failure of memory.
Citrus extracts: being the fully natural green compound that extracts from orange peel, is the mixture that a series of flavone compounds with notable biological activity form, and has the effects such as anti-oxidant, anticancer, anti-inflammatory, antiallergy.Not only have unique armaticity, good water-soluble and significant pharmacological action, and be the newfound nutrient of a class.Clinical research confirmation, Flavonoid substances be the pharmacology factor be again important trophic factors.
Vitamin E: being again tocopherol, is a kind of powerful antioxidant, can effectively stop becoming sour of the interior aliphatic acid of food and alimentary canal, and Cell protection is avoided the harmful substance that the unsaturated fat acid oxidase produces; Promote the secretion of pituitary gonadotropic hormone, promote generation and the activity of sperm; Reduce the generation of lipid peroxide, the protection body cell is avoided the murder by poisoning of free radical; Improve immunity of organisms; Delay senility pre-anti-cancer and multiple chronic disease.
Vitamin C: improve the utilization of iron, calcium and folic acid; Prevent and treat scurvy; Promote the synthetic of collagen, abundant collagen helps anti-cancer; Improve the oxidation resistance of human body; Delay senility; Opposing is infected; Can promote the drainage of cholesterol, prevent that cholesterol from depositing at Wall of Artery, even can make the atheromatous plaque dissolving of deposition; The injury that strong antioxidant action can be resisted the radical pair cell prevents the variation of cell; Blocking-up nitrite and secondary amine form the strong carcinogen nitrosamine.
Cobastab
6: protection DNA's is synthetic, improves immunity, anticancer; Regulate the content of male sex hormone; Promote Cobastab
12, zinc absorption; Participate in neurotransmitter, glycogen, sphingomyelin, ferroheme, steroids and nucleic acid and all amino acid metabolisms; Reduce the effect of chronic disease.
Cobastab
12: promote the synthetic of protein, affect growing of infant during shortage; Improve the folic acid utilization rate, transfer and the storage in vivo of protection folic acid; As the co-factor of transmethylase, participate in the synthetic of methionine, thymidine etc.
Beta carotene: beta carotene can be used as the approach that obtains vitamin A, and vitamin A is one of necessary raw material of manufacturing hormone, and it has also participated in the formation of sperm; To Green Tea Extract one of the most effective antioxidant; Strengthening immune system is built up resistance, and strengthens reproductive system and urinary system function, improves sperm motility, the prevention prostatic disorders; Help to keep the lubricated and transparency of cornea, promote the health of eyes; Pre-anti-cancer and angiocardiopathy; Improve and strengthen the respiratory system function.
Folic acid: be the important substance that improves sperm quality, when folic acid presented deficiency in males, the concentration of seminal fluid and motility of sperm descended, and meeting is so that the chance minimizing of becoming pregnant; The prevention fetal anomaly, congenital neural-tube defect; Antitumor action can cause cancer cell-apoptosis, and the gene expression of cancer cell is had certain influence; Can be used for treating atrophic gastritis, suppress the bronchus squamous transforms and control causes because of hyperhomocysteinemiainjury coronary sclerosis, myocardial damage and miocardial infarction etc.
Selenium in the selenium-containing compound: mainly include sodium selenite, sodium selenate and Se-enriched yeast etc., improve and improve sexual function, increase the energy source of sperm motility, improve the energy of sperm; Delay senility, antioxidation can be removed interior free yl, gets rid of the generation that vivotoxin can effectively suppress lipid peroxide, the not oxidated loss of Cell protection; Strengthen immune function of human body, prevent blood clot, remove cholesterol; Prevention diabetes and angiocardiopathy.
Zinc in the zinc compound: mainly include zinc sulfate, zinc lactate, zinc chloride, zinc citrate and zinc carbonate etc., adjust immune function; Keep the normal spermatogenesis of the male sex, promote the generation of stosterone, improve the mobility of sperm, strengthen the ability of male erectile and ejaculation; Promote growing of human body; Keep human normal appetite, scarce zinc can cause the sense of taste to descend, and apocleisis, partial eclipse even different food occur; Affect metabolism and the normal vision of vitamin A, the absorption of vitamin A be unable to do without zinc; The long-term insufficiency of intake of zinc will cause sperm rareness and orchiatrophy.
Compatibility explanation of the present invention:
Product safety, effective, quality controllable be that the most basic requirement-----of health caring product prescription combines natural active matter and nutrient, carry out reasonably combined, can give full play to the unique effect of each component: siberian Ginseng P.E is a kind of immunopotentiator, the metabolism of energy balance the body, remove interior free yl, strengthen human body to the resistance of various diseases, it is typical strong class medicine, what it was emphasized is that the multiple beneficial composition is directly played a positive role for human body, and effect is more direct; Lycopene is the powerful antioxidant that present occurring in nature is found, can singlet-oxygen quenching and eliminate peroxylradicals; This effect outclass other carotenoid and vitamin E, can inhibitory mutagenesis, Cell differentiation inducing activity, anti-oxidant, removing free radical, reduction nucleic acid damaging, reduce the plurality of health care functions such as angiocardiopathy, pre-anti-cancer, also is to emphasize that functional component directly plays a role to human body; Therefore choose siberian Ginseng P.E and lycopene is the main component of anti-oxidant special meal nutritional food.Various vitamins and mineral matter are that the man is easy to lack, and have again anti-oxidant, spermatogenesis simultaneously; Contained OPC has very strong antioxidation in the grape seed extract; These compositions are as the composite composition of siberian Ginseng P.E and lycopene, and they have similar effect in a lot of functions.Thereby natural active matter and nutrient compatibility, can play mutual promotion, complement each other, complementary " monarch " effect, play more perfect than single component, more comprehensively with powerful effect.
The present invention is with respect to the major advantage of prior art:
The present invention is a kind of novel, comprehensive nutraceutical, can improve male sex's physiological function comprehensively, removes free radical, improves the effect of immunity.
Siberian Ginseng P.E used in the present invention and lycopene are natural active materials, have effect anti-oxidant, that improve Male vitality; Vitamin in the invention and the nutrients such as mineral matter are except being the nutrient that generally lacks of China resident simultaneously, also has the effect that improves male sex's physiological function, their addition is with reference to Chinese residents Chinese DRIs every day, combination by natural products and nutrient, the present invention is had to be incorporated multiple different efficacies composition in the product, these compositions cooperatively interact, and synergy comprehensively, balancedly is to prepare to want baby's man to supplement the nutrients.Therefore functional component and the materials safety of product are high, and long-term edible having no side effect is that the man prepares to give birth to special-purpose desirable nutrient supplement food.
The preparation fertility man's of the present invention's preparation special meal nutritional food can be made into the various ways such as capsule, tablet, pulvis, granule, oral liquid, paste.
The specific embodiment
Below in conjunction with embodiment, the present invention will be further described, and following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Embodiment 1
Be applicable to the man's for preparing to give birth to special meals nutrient soft capsule, its material composition includes lycopene, siberian Ginseng P.E, vitamin E, vitamin C, Cobastab
6, Cobastab
12, folic acid, beta carotene, sodium selenite, zinc sulfate, grape-kernel oil, soybean lecithin, the weight proportion of each material composition is:
Lycopene 5mg siberian Ginseng P.E 200mg
Vitamin E 30mg vitamin C 100mg
Microorganism B
61.3mg Cobastab
122.4 μ g
Folic acid 100 μ g beta carotenes 250 μ gRE
Sodium selenite (Se content 50 μ g) 110 μ g zinc sulfate (zinc content 12mg) 35mg
Soybean lecithin 50mg grape-kernel oil 100mg
The preparation method:
(1) preparation technology of siberian Ginseng P.E: take by weighing a certain amount of Radix Acanthopanacis Senticosi root, pulverized the 10-20 mesh sieve, filter behind the 75% alcohol reflux extraction 12h with 7 times of amount volumes, get filter residue; With the water boil lixiviate twice of 8-10 times of volume, each 1-2 hour, extract merged, and is concentrated; Concentrate filters with 75% ethanol sedimentation, and sediment adds an amount of water, then carries out spray-drying, gets dry thing, is siberian Ginseng P.E.
(2) with lycopene, siberian Ginseng P.E, vitamin C, vitamin E, beta carotene, the Cobastab of above-mentioned formula ratio
12, folic acid, Cobastab
6, sodium selenite, zinc sulfate mix, grind with grinder after adding an amount of grape-kernel oil; Cera alba with an amount of grape-kernel oil heat fused, is started the vacuum emulsification tank, drop into successively the soybean lecithin of formula ratio, stir, fusing; Material is dropped into the vacuum emulsification tank, stir, grind to get content by grinder; Gelatin, glycerine, purified water ratio in accordance with regulations is mixed and heated to certain temperature (75 ℃) to be stirred to gelatin and to dissolve fully, vacuumize degassing 30 minutes (vacuum 0.09MPa), get foregoing thing and softgel shell solution, adopt pressing compressing with the soft capsule production equipment, namely get the special meals nutrient soft capsule that is applicable to the man for preparing to give birth to after the drying.
Embodiment 2
Be applicable to the man's for preparing to give birth to special meals nutrient soft capsule, its material composition includes lycopene, siberian Ginseng P.E, vitamin E, vitamin C, Cobastab
6, Cobastab
12, folic acid, beta carotene, sodium selenite, zinc sulfate, soybean lecithin, grape-kernel oil, the weight proportion of each material composition is:
Lycopene 10mg siberian Ginseng P.E 300mg
Vitamin E 65mg vitamin C 150mg
Cobastab
6The 5mg Cobastab
125 μ g
Folic acid 400 μ g beta carotenes 600 μ gRE
Sodium selenite (Se content 75 μ g) 165 μ g zinc sulfate (zinc content 14mg) 41mg
Soybean lecithin 75mg grape-kernel oil 340mg
The special meals nutrient soft capsule that is applicable to the man for preparing to give birth to prepares according to the preparation method among the embodiment 1.
Embodiment 3
Be applicable to the man's for preparing to give birth to special meals nutrient soft capsule, its material composition includes lycopene, siberian Ginseng P.E, vitamin E, vitamin C, Cobastab
6, Cobastab
12, folic acid, beta carotene, sodium selenite, zinc lactate, grape-kernel oil, soybean lecithin, the weight proportion of each material composition is:
Lycopene 30mg siberian Ginseng P.E 500mg
Vitamin E 100mg vitamin C 300mg
Cobastab
6The 8mg Cobastab
128 μ g
Folic acid 400 μ g beta carotenes 1250 μ gRE
Sodium selenite (Se content 100 μ g) 220 μ g zinc lactates (zinc content 20mg) 91mg
Soybean lecithin 100mg grape-kernel oil 850mg
The special meals nutrient soft capsule that is applicable to the man for preparing to give birth to prepares according to the preparation method among the embodiment 1.
Embodiment 4
Be applicable to the man's for preparing to give birth to special meals nutrient soft capsule, its material composition includes lycopene, siberian Ginseng P.E, vitamin E, vitamin C, Cobastab
6, Cobastab
12, folic acid, beta carotene, sodium selenite, zinc sulfate, grape-kernel oil, soybean lecithin, glutathione, L-arginine, citrus extracts, the weight proportion of each material composition is:
Lycopene 10mg siberian Ginseng P.E 300mg
Vitamin E 65mg vitamin C 150mg
Cobastab
6The 5mg Cobastab
125 μ g
Folic acid 400 μ g beta carotenes 600 μ gRE
Sodium selenite (Se content 50 μ g) 110 μ g zinc sulfate (zinc content 14mg) 41mg
Grape-kernel oil 350mg soybean lecithin 75mg
Glutathione 2.5mg L-arginine 10mg
Citrus extracts 10mg
(1) preparation technology of citrus extracts: the ethanol water of the oranges and tangerines powder through pulverizing and 75% is placed extractor for 1:1-5 by weight, under reflux state, extracted 0.5-1 hour, repeat merging filtrate 2-3 time, through concentrated, dry, namely get citrus extracts.
(2) the special meals nutrient soft capsule that is applicable to the man for preparing to give birth to prepares according to the preparation method among the embodiment 1.
Embodiment 5
Be applicable to the man's for preparing to give birth to special meals nutrient tablet, its material composition includes lycopene, siberian Ginseng P.E, vitamin E, vitamin C, Cobastab
6, Cobastab
12, folic acid, beta carotene, sodium selenite, zinc sulfate, grape seed extract, the weight proportion of each material composition is:
Lycopene 10mg siberian Ginseng P.E 200mg
Vitamin E 35mg vitamin C 130mg
Cobastab
61.3mg Cobastab
122.4 μ g
Folic acid 400 μ g beta carotenes 600 μ gRE
Sodium selenite (Se content 50 μ g) 110 μ g zinc sulfate (zinc content 12mg) 35mg
Grape seed extract 80mg
The preparation method:
(1) siberian Ginseng P.E prepares the method among employing and the embodiment 1.
(2) preparation technology of grape seed extract: add grape pip 5-8 and doubly measure, temperature is that 95-100 ℃ water circulates and extracts 2-3 time, each 2-3 hour, and the merging extract; Concentrated, dry, namely get grape seed extract.
(2) for guaranteeing product quality, all operations all should carry out in the clean dried environment.Select above-mentioned lycopene, siberian Ginseng P.E, vitamin E, vitamin C, Cobastab
6, Cobastab
12, folic acid, beta carotene, sodium selenite, zinc sulfate, grape seed extract, behind weight proportion adding material crushing screening, mix; The above-mentioned raw material that mixes added first forward is dry mixed stirring in the mixer, 10% dextrin starch slurry can be divided to count several times and carry out wet mixing in the mixer and close, continuous stirring is made softwood; Getting above-mentioned softwood sends in the oscillating granulator and granulates with 16 eye mesh screens; The particle that makes is put into baking oven dry, moisture can stop drying 3% when following, gives free rein to the cold of drying in the air; Then cross 14 eye mesh screens and carry out whole grain, make the single-size of the size that meets the requirements; Add and carry out compressing tablet after moderate lubrication agent and disintegrant always mix; Through check, packing, finished product, namely make the man's who prepares fertility special meals nutrient tablet.
Embodiment 6
Be applicable to the man's for preparing to give birth to special meals nutrient tablet, its material composition includes lycopene, siberian Ginseng P.E, vitamin E, vitamin C, Cobastab
6, Cobastab
12, folic acid, beta carotene, sodium selenite, zinc sulfate, grape seed extract, glutathione, citrus extracts, L-arginine, the weight proportion of each material composition is:
Lycopene 20mg siberian Ginseng P.E 500mg
Vitamin E 100mg vitamin C 150mg
Cobastab
6The 5mg Cobastab
128 μ g
Folic acid 400 μ g beta carotenes 1250 μ gRE
Sodium selenite (Se content 100 μ g) 220 μ g zinc sulfate (zinc content 14mg) 41mg
Grape seed extract 150mg glutathione 2.5mg
L-arginine 10mg citrus extracts 10mg
The special meals nutrient tablet that is applicable to the man for preparing to give birth to prepares according to the preparation method among the embodiment 5.
The implementation result experiment
The man's who prepares to give birth to being applicable among the embodiment 2 special meals nutrient soft capsule is implemented anti-oxidant experiment, tests according to method of regulation in " health food check and assessment technique standard ".
Adult of the present invention (60kg) meter recommended intake 1.0g/d, be 0.017g/Kg.bw, what animal was adopted is that Kunming kind Aged Mice is as experimental system, experiment by 5 times of human intaking amounts, 10 times, 20 times establish respectively 0.085,0.17, three dosage groups of 0.34g/Kg.bw, be equivalent to every kilopond injected in mice siberian Ginseng P.E and be respectively 17.8mg, 35.6mg and 71.2mg; Lycopene is respectively 4.4mg, 8.8mg and 17.6mg; Vitamin E is respectively 3.1mg, 6.2mg and 12.4mg; Vitamin C is respectively 11.5mg, 23.1mg and 46.2mg.Behind the gavage 30d, 12h before experiment, prohibit water, fasting, take by weighing body weight, carry out in advance the last gavage half an hour, animal eyeball is extractd blood sampling, method according to regulation in " health food check and assessment technique standard " is tested, and detects respectively vigor and lipid peroxide catabolite trace MDA (MDA) content of superoxide dismutase in the mice serum (SOD) vigor, glutathione peroxidase (GSH-Px).
1, Mouse Weight result of variations
Draw by first body weight and last body weight determination result to each experiment mice of anti-oxidation function, the initial body weight difference not statistically significant (P ﹥ 0.05) of mouse between each experimental group, the heavy and blank group more equal not statistically significant (P ﹥ 0.05) of dosage group experiment opisthosoma of each product.
2, the analysis of experimental data of anti-oxidant each index
Antioxidant Indexes comparative result in table 1 Mice Body
Annotate:
*Expression relatively has statistical significance, P＜0.05 with blank group
*Relatively there were significant differences with blank group in expression, P＜0.01
(1) special meals nutrient soft capsule of the present invention has the effect of the raising SOD vigor stronger than one-components such as siberian Ginseng P.E and lycopenes.
Table 1 result demonstration for the SOD effect of vigor in the mice serum, although all relatively increase with the blank group in each one-component, does not have statistical significance, and special meals nutrient soft capsule of the present invention then has statistical significance.Middle dosage group, each composition can both improve the SOD vigor, all has statistical significance, and the present invention is significant difference then; Only in high dose group, all one-components just improve SOD vigor the same as the present invention relatively have significant difference with blank group.
Therefore, the present invention is more much better than than simple siberian Ginseng P.E, lycopene, vitamin E and vitamin C in the effect of raising SOD vigor.
(2) special meals nutrient soft capsule of the present invention has the effect of the raising GSH-Px vigor stronger than one-components such as siberian Ginseng P.E and lycopenes.
Table 1 result shows, low dose group, and the present invention can obviously improve the GSH-Px vigor, has significant difference, and each one-component not statistically significant all.Middle dosage group, the present invention can obviously improve the GSH-Px vigor, has significant difference, and vitamin C can not obviously improve GSH-Px vigor, not statistically significant; Simple siberian Ginseng P.E, lycopene and vitamin E have significant difference.In high dose group, each composition all has statistical significance, but the present invention has significant difference, and therefore, the present invention has stronger raising GSH-Px vigor effect than one-component.Illustrate that siberian Ginseng P.E, lycopene, vitamin C and vitamin E synergy can significantly strengthen GSH-Px vigor in the mice serum, more much better than than each component independent role.
(3) the present invention has the inhibition MDA generation effect stronger than one-components such as siberian Ginseng P.E and lycopenes.
From each experimental group on MDA content the mice serum to affect the result as shown in table 1.As can be seen from the table: blank group MDA content is the highest, reaches 12.14 ± 0.91 (MDA/mmol/mL); And the present invention is minimum, only is 5.23 ± 0.76 (MDA/mmd/mL).The a little higher than special meals nutrient soft capsule of the present invention of each one-component dosage group.The significance test result shows: relatively, the impact of MDA content in the mice serum is not had statistical significance (P ﹥ 0.05) between each oligomict low dose group and the blank group; Middle dosage group, siberian Ginseng P.E and vitamin C not statistically significant; High dose group, vitamin C do not have statistical significance, and only have dosage group of the present invention to compare significant difference (P＜0.01) with the blank group, have illustrated that the present invention has significant reducing effect to MDA content in the mice serum.Can find out from above experimental result: the MDA content that has eaten the mice serum of special meals nutrient soft capsule of the present invention is starkly lower than blank group, and SOD and GSH-Px vigor will be organized mouse apparently higher than blank.
In sum, the present invention is formed by compatibilities such as siberian Ginseng P.E, lycopene, vitamin C, vitamin Es, from above analysis of experimental data explanation, compare the one-components such as siberian Ginseng P.E, lycopene, vitamin C, vitamin E, effect of the present invention more comprehensively, more perfect functions can significantly improve SOD, the GSH-Px vigor of mice serum and reduce MDA content in the body.The present invention has obvious antioxidation, can remove too much free radical in the body, and this anti-oxidation function is better than each one-component, has positive effect to improving male sex's physiological function.
The present invention has comprehensive enhancing man physiological function, plays effect anti-oxidant, that remove free radical; Therefore, edible safety, clear efficacy behind the compatibility of the present invention are good Ricipe for health care food.
Claims (1)
1. be applicable to the man's for preparing to give birth to nutraceutical, it is characterized in that the shared weight proportion of each material composition is:
Lycopene 2-30mg siberian Ginseng P.E 100-500mg
Vitamin E 10-100mg vitamin C 50-300mg
Cobastab
60.5-8mg Cobastab
121.5-8 μ g
Folic acid 100-400 μ g beta carotene 250-1250 μ gRE
Se content 20-100 μ g zinc content 5-20mg
Grape-kernel oil 100-1000mg soybean lecithin 30-100mg
Grape seed extract 50-200mg
Glutathione 1-10mg citrus extracts 5-20mg
L-arginine 5-25mg.
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| CN2011102422080A CN102318821B (en) | 2011-08-23 | 2011-08-23 | Special meal nutritional food applicable to males preparing childbearing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102422080A CN102318821B (en) | 2011-08-23 | 2011-08-23 | Special meal nutritional food applicable to males preparing childbearing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102318821A CN102318821A (en) | 2012-01-18 |
| CN102318821B true CN102318821B (en) | 2013-02-06 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011102422080A Active CN102318821B (en) | 2011-08-23 | 2011-08-23 | Special meal nutritional food applicable to males preparing childbearing |
Country Status (1)
| Country | Link |
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| CN (1) | CN102318821B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104305223A (en) * | 2014-09-29 | 2015-01-28 | 于惊涛 | Nutrient supplement composition suitable for smokers |
| CN105707890A (en) * | 2016-03-11 | 2016-06-29 | 福格森（武汉）生物科技股份有限公司 | Soft capsule suitable for females in pregnancy-preparation stage to take |
| CN106578899A (en) * | 2016-12-30 | 2017-04-26 | 贝克尔（天津）药业有限公司 | Instant cereal powder for improving male sperm motility |
| CN107996718A (en) * | 2017-12-12 | 2018-05-08 | 安徽赛博蓝医疗科技有限公司 | A kind of composition health food with prenatal and postnatal care and its production technology |
| CN110613124A (en) * | 2019-09-18 | 2019-12-27 | 孙启城 | Health food containing L-carnitine and astaxanthin |
| CN112386609A (en) * | 2020-10-29 | 2021-02-23 | 云南师范大学 | Formula-optimized compound vitamin |
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| CN1533701A (en) * | 2003-03-28 | 2004-10-06 | 戚海波 | Eaible beautifying and skin protection milk powder liquid state milk specially prepared concentrated milk |
| CN102133250A (en) * | 2011-03-15 | 2011-07-27 | 郭景龙 | Medicinal composition with effect of improving immunity |
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| CN1533701A (en) * | 2003-03-28 | 2004-10-06 | 戚海波 | Eaible beautifying and skin protection milk powder liquid state milk specially prepared concentrated milk |
| CN102133250A (en) * | 2011-03-15 | 2011-07-27 | 郭景龙 | Medicinal composition with effect of improving immunity |
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|---|---|
| CN102318821A (en) | 2012-01-18 |
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