CN102293877A - Chinese herbal medicine for treating nasopharyngeal carcinoma - Google Patents
Chinese herbal medicine for treating nasopharyngeal carcinoma Download PDFInfo
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- CN102293877A CN102293877A CN2011102382399A CN201110238239A CN102293877A CN 102293877 A CN102293877 A CN 102293877A CN 2011102382399 A CN2011102382399 A CN 2011102382399A CN 201110238239 A CN201110238239 A CN 201110238239A CN 102293877 A CN102293877 A CN 102293877A
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Abstract
The invention discloses a Chinese herbal medicine for treating nasopharyngeal carcinoma, which is characterized in that the Chinese herbal medicine comprises the following components: 50-100 parts of water pack, 30-50 parts of small centipeda herb, 20-40 parts of bushy sophora and 20-40 parts of cordate houttuynia. According to the Chinese traditional medicine and modern pharmacological research accomplishment, the medicine formula of the present invention selects vitamin B1, trypsin inhibitor-water pack, cooperates with small centipeda herb which diminishes herpes and tumor, removes toxicity and disinhibits orifices, bushy sophora which cleans heat, removes toxicity and relieves sore throat, as well as cordate houttuynia which cleans heat and removes toxicity and eliminating tumor, rapidly inhibites and neutralizes pin1 (polypeptide prolyl cis trans isomerase), so that the purpose of rapidly inhibiting and treating nasopharyngeal carcinoma can be achieved.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of nasopharyngeal carcinoma, relate in particular to a kind of Chinese herbal medicine for the treatment of nasopharyngeal carcinoma.
Background technology
As everyone knows, current also do not have a kind of medicine can treat nasopharyngeal carcinoma separately, and main treatment means is to undergo surgery, radiotherapy, chemotherapy.Not only the patient will experience pain of a narrow escape from death, and family is heavily in debt, and still will experience life and death in the end and part.
It is reported the annual newly-increased cancer patient about 10,000,000 in the whole world, modern medicine study shows, the formation of various endometrial carcinomas and Pinl(polypeptidyl prolyl cis/trans isomerase) direct relation arranged.Pinl acts on the fissional albumen of multiple adjusting in the cell cycle, be a kind of high conservative, special.The isomerase of phosphorylation, its allows cell with a kind of efficient and accurate way opens or closes the function of some phosphoprotein.The imbalance of this sophisticated signal mechanism can cause the generation of cell transformation and tumor.Utilize proteomic techniques to discover the high expressed of Pinl at the differential protein of gastric cancer.The expression of Pinl has promoted the generation of hepatocarcinoma, and PangR etc. discover that Pinl crosses and expresses in hepatocarcinoma.Bao etc. have studied the expression of Pinl in human 60 kinds of tumor tissues, and the result is presented at most common tumor, in carcinoma of prostate, breast carcinoma, cervical cancer, cerebroma, pulmonary carcinoma, colon cancer, all detects Pinl and crosses expression.Wherein SW620 colon carcinoma cell line and PC-3(prostate cancer cell line) in the expression of Pinl the highest.In the research of breast cancer tissue and breast cancer cell, show, Pinl not only concentrates in karyon, and also highly expresses in endochylema, compares with normal galactophore tissue, Pinl can be up to 10 times in the breast carcinoma, the low easier early stage recurrence of expresser's postoperative of Pinl high expressed person.The research of Nakashima and Hangen etc. finds that in succession Pinl crosses and expresses in thyroid tumor and leukemia blast cell.Pinl can and suppress apoptosis by number of mechanisms inducing cell propagation, causes the generation of tumor.
By Cyclin D1 approach, cyclin D1(Cyclin D1) be the important target protein of Pinl.Cyclin D1 is important member in the plain family of G1 cycle, acts on the G1 phase in the cell cycle, can interact with multiple protein to promote that cell enters the S phase by the G1 phase, accelerates the cell cycle conversion speed, cause uncontrolled cellular proliferation, thereby form canceration,
P sudden change is to cause tumorigenic important mechanisms, and Pinl can combine with the sudden change P of phosphorylation by its ww district, make its generation suitable/the anteiso-structure, the stability of enhancing saltant P, thereby the generation of promotion tumor.
In a word: Pinl is by the multi-section position, and too many levels is controlled many cell processes, and it totally is that effect is to cause the cancer signal infinitely to enlarge, and promotes that cell transformation and propagation are out of control, causes the generation of tumor.
Nasopharyngeal carcinoma is the malignant tumor that nasopharynx part takes place, and is one of common carcinoma of China.According to the rough estimate of World Health Organization (WHO), about 80% nasopharyngeal carcinoma occurs in China in the world, and sickness rate age curve rises by beginning in 20 years old, 50-60 year age group be summit, main clinic symptoms: nasal obstruction tears blood, little expectoration Huang.Bitter taste in the mouth and dry throat, the time headache is arranged, stomach is received as usual, the yellowish urine constipation, side of body rib distension is had a dizzy spell, the enlargement of neck nuclear, blurred vision, diplopia, face fiber crops wry tongue, dysphoria and insomnia.
Summary of the invention
The object of the invention is to provide a kind of Chinese herbal medicine that can effectively treat nasopharyngeal carcinoma and the generation of prevention nasopharyngeal carcinoma for overcoming the deficiencies in the prior art.Its concrete composition by weight is:
Rhizoma sagittariae sagittifoliae 50-100 Herba Centipedae 30-50
Radix Sophorae Tonkinensis 20-40 Herba Houttuyniae 20-40.
The weight portion ratio range of the formula optimization of preparation Chinese herbal medicine of the present invention is:
Rhizoma sagittariae sagittifoliae 50-80 Herba Centipedae 30-40
Radix Sophorae Tonkinensis 20-30 Herba Houttuyniae 20-30.
Chinese herbal medicine optimum weight part proportioning of the present invention is:
Rhizoma sagittariae sagittifoliae 75 Herba Centipedae 35 Radix Sophorae Tonkinensiss 25 Herba Houttuyniae 25.
Herbal composite preparation method of the present invention: earlier Rhizoma sagittariae sagittifoliae is cleaned, dried, pulverized 80 eye mesh screens with pulverizer, with Herba Centipedae, Radix Sophorae Tonkinensis, Herba Houttuyniae is pulverized the back and is got final product by above-mentioned component mixed bag distribution packaging.
The instructions of taking of medicine of the present invention: unpack and convert clothes with cold boiled water or pure water, consumption is each seven gram, three times on the one.
Adopt herbal composite of the present invention successively to treat 13 routine nasopharyngeal carcinoma patients, nasal obstruction after the patient took medicine 3 days, headache, disappearance.After 7 days: bitter taste in the mouth and dry throat, tears blood, side of body rib distension is had a dizzy spell the blurred vision transference cure.Recovery from illness after one to three months.
Lee * *, the man, 50 years old, silver people from cities and towns in Yuechi County, Sichuan was because of the inspection of being hospitalized for treatment of nasal obstruction tears blood, be diagnosed as nasopharyngeal carcinoma through hospital, through radiotherapy in the treatment after three months effect undesirable, begin upon somebody's introduction to take medicine of the present invention, nasal obstruction tears blood disappears after taking medicine three days, take further consultation after three months, the doctor thinks and fully recovers.
Zheng * *, man, 55 years old, Sichuan Nanchong City Shunqing District people, excuse is dizzy dizzy, and neck nuclear enlargement treatment hospitalized to have a thorough examination is diagnosed as nasopharyngeal carcinoma through hospital, do not take effect in four months really through chemotherapeutic treatment, begin upon somebody's introduction to take medicine of the present invention, after taking medicine seven days, its symptom is clearly better, take further consultation after three months, its all symptoms all disappear.
From technical scheme of the present invention as can be seen; Chinese herbal medicine prescription of the present invention is according to motherland's traditional medicine and modern pharmacological research achievement; choose the Rhizoma sagittariae sagittifoliae that contains vitamin B1, trypsininhibitory substance; it is swollen to be combined with the bleb of loosing, the Herba Centipedae of the sharp key that detoxifies, the Radix Sophorae Tonkinensis of heat-clearing and toxic substances removing sore-throat relieving; the energy heat-clearing and toxic substances removing; the Herba Houttuyniae of dispersing tumor suppresses rapidly and the pinl(polypeptidyl prolyl cis/trans isomerase that neutralized), thus reached rapid inhibition and the treatment nasopharyngeal carcinoma goal of the invention.
Embodiment 1: take by weighing raw material by following proportioning
Rhizoma sagittariae sagittifoliae 50 Herba Centipedae 30 Radix Sophorae Tonkinensiss 20 Herba Houttuyniae 30.
Herbal composite preparation method of the present invention is: earlier Rhizoma sagittariae sagittifoliae is cleaned, dried, pulverized 80 eye mesh screens with pulverizer, Herba Centipedae, Radix Sophorae Tonkinensis, Herba Houttuyniae are pulverized the back and got final product by bag distribution packaging after the above-mentioned component mixed.
Embodiment 2: take by weighing raw material by following proportioning
Rhizoma sagittariae sagittifoliae 80 Herba Centipedae 40 Radix Sophorae Tonkinensiss 25 Herba Houttuyniae 25.
The preparation method of present embodiment is with embodiment 1.
Embodiment 3: take by weighing raw material by following proportioning
Rhizoma sagittariae sagittifoliae 70 Herba Centipedae 40 Radix Sophorae Tonkinensiss 25 Herba Houttuyniae 25.
The preparation method of present embodiment is with embodiment 1.
Claims (3)
1. a Chinese herbal medicine for the treatment of nasopharyngeal carcinoma is characterized in that: make by following component
Rhizoma sagittariae sagittifoliae 50-100 Herba Centipedae 30-50
Radix Sophorae Tonkinensis 20-40 Herba Houttuyniae 20-40.
2. a kind of Chinese herbal medicine for the treatment of nasopharyngeal carcinoma according to claim 1 is characterized in that: make by following component
Rhizoma sagittariae sagittifoliae 50-80 Herba Centipedae 30-40
Radix Sophorae Tonkinensis 20-40 Herba Houttuyniae 20-30.
3. a kind of Chinese herbal medicine for the treatment of nasopharyngeal carcinoma according to claim 1 is characterized in that: make by following component
Rhizoma sagittariae sagittifoliae 75 Herba Centipedae 35 Radix Sophorae Tonkinensiss 25 Herba Houttuyniae 25.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011102382399A CN102293877A (en) | 2011-08-19 | 2011-08-19 | Chinese herbal medicine for treating nasopharyngeal carcinoma |
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| CN2011102382399A CN102293877A (en) | 2011-08-19 | 2011-08-19 | Chinese herbal medicine for treating nasopharyngeal carcinoma |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109516995A (en) * | 2018-09-20 | 2019-03-26 | 广西壮族自治区药用植物园 | Phenyl benzofurans compound, and preparation method thereof, composition and medical usage |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1475204A (en) * | 2002-06-30 | 2004-02-18 | 丛繁滋 | Medicinal Composition, dry powder vapor, nebula, nebula auxiliary preparation for use through mouth and nose and its preparation method |
| CN1559545A (en) * | 2004-03-10 | 2005-01-05 | 张土荣 | Immune balancing energy restoring pill and its manufacturing method |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1475204A (en) * | 2002-06-30 | 2004-02-18 | 丛繁滋 | Medicinal Composition, dry powder vapor, nebula, nebula auxiliary preparation for use through mouth and nose and its preparation method |
| CN1559545A (en) * | 2004-03-10 | 2005-01-05 | 张土荣 | Immune balancing energy restoring pill and its manufacturing method |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109516995A (en) * | 2018-09-20 | 2019-03-26 | 广西壮族自治区药用植物园 | Phenyl benzofurans compound, and preparation method thereof, composition and medical usage |
| WO2020057028A1 (en) * | 2018-09-20 | 2020-03-26 | 广西壮族自治区药用植物园 | Phenylbenzofuran compound, preparation method therefor, composition and medical use thereof |
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Application publication date: 20111228 |