CN107177510A - A kind of fontanesia leaf shelf fungus and its purposes in medicine is prepared - Google Patents
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- CN107177510A CN107177510A CN201710129956.5A CN201710129956A CN107177510A CN 107177510 A CN107177510 A CN 107177510A CN 201710129956 A CN201710129956 A CN 201710129956A CN 107177510 A CN107177510 A CN 107177510A
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Abstract
The invention belongs to microbial technology field, and in particular to a kind of fontanesia leaf shelf fungus.The entitled Phylloporia fontanesiae of fontanesia leaf shelf fungus Latin, were preserved in China Committee for Culture Collection of Microorganisms's common micro-organisms center, deposit number is on January 27th, 2016：CGMCC No.11905.Moreover, it relates to purposes of the fontanesia leaf shelf fungus in preparing prevention and/or treatment tumour or improving medicine, health products, food, drink or the tea of immunity.
Description
Technical field
The present invention relates to microbial technology field, and in particular to a kind of fontanesia leaf shelf fungus and its use in medicine is prepared
On the way.
Background technology
At present, the treatment method for tumour has：Operative treatment, radiotherapy, PCI and drug therapy etc..Wherein
Operative treatment has good curative effect to early stage patient, but its medical expense is expensive, and not good to patients with terminal therapeutic effect, also has
Some patients can not carry out operative treatment because of physical reason, and such as patient has serious cardiopulmonary or hepatic and kidney function obstacle.Treatment is swollen in addition
Mostly expensive and effect is not good, some medicines although the medicine species of knurl is many, dosage is big, species is more, no
Only effect is bad, but also can bring many side effects, produces adverse consequences.
Operative treatment is larger to actual bodily harm；Radiotherapy is always because of the side effect of its " fight the enemy 1,000, from damage 800 "
Extensively denounced, a course for the treatment of is got off, patient's immunity dramatic decrease, mostly frail to can't bear, in poor health, side effect is likely to
Last straw as the patient that crushes.Later targeted drug arises at the historic moment, energy precise guidance cancer cell, therefore greatly reduces
Damage to body.Targeted therapy, is that on a molecular scale, for clearly carcinogenic site, (site can be swollen
A protein molecular or a genetic fragment inside oncocyte), to design corresponding medicine, medicine enters
It can specifically select carcinogenic site to be had an effect to be combined in vivo, make tumor cell specific dead, without involving tumour
The normal tissue cell of surrounding.Targeting medicine has very strong side effect：Fash, abdominal pain diarrhea, trick pain cracking, nasal bleeding,
Tired, hair loss, digestive discomfort etc., targeting medicine can only delay the state of an illness and can not cure.
The medicinal history of Chinese large-sized fungi is long,《Sheng Nong's herbal classic》With《Compendium of Materia Medica》Describe the medicinal of fungi
Value, wherein ganoderma lucidum (Ganderma lucidum), Poria cocos (Poria cocos) and umbellate pore furgus (Grifola umbellata) etc.
It is used for the treatment of cancer.The Modern Literature of anticancer epiphyte is started from 1903, and the broad scale research that fungus antitumor is acted on is begun
Twentieth century sixties, it has now been found that about 650 kinds of basidiomycetes have antitumor activity.It is big that the chemosensitive test of fungi can be divided into two
Class, macromolecular substances and small-molecule substance, macromolecular substances are mainly polysaccharide and the polysaccharide being connected with albumen, and small molecule mainly has
Phenolic compound, polyketides, terpenoid and steroidal etc..
People still suffer from demand for good effect, the safe medicine for being used to treat tumour or raising immunity.
The content of the invention
The health demand growing with people in view of the shortcomings of the prior art, it is an object of the present invention to provide one kind
New fontanesia leaf shelf fungus.
It is a further object of the present invention to provide a kind of fungal extract, it is to be extracted using fontanesia leaf shelf fungus as raw material
Arrive.
It is yet another object of the invention to provide a kind of epiphyte composition, it contains above-mentioned fontanesia leaf shelf fungus or above-mentioned
Fungal extract.
It is yet another object of the invention to provide above-mentioned fontanesia leaf shelf fungus, fungal extract or epiphyte composition in system
It is standby to prevent and/or treat tumour or improve the purposes in medicine, health products, food, drink or the tea of immunity.
The fontanesia leaf shelf fungus that the present invention is provided, the entitled Phylloporia fontanesiae of its Latin, in 2016 1
The moon is preserved in China Committee for Culture Collection of Microorganisms's common micro-organisms center (CGMCC) on the 27th, and deposit number is：
CGMCC No.11905。
The fontanesia leaf shelf fungus can be used for preventing and/or treat tumour (including benign tumour and malignant tumour) and carry
High immunity, and evident in efficacy, with low cost, safe and reliable, better tolerance, toxic side effect are small, instant effect, compliance are good.
Preferably, rRNA gene ITS region sequences (including the 18S rRNA fragments, ITS1,5.8S of the fontanesia leaf shelf fungus
RRNA, ITS2 complete sequence and 28S region sequences fragment) it is SEQ ID NO:1, it is as follows：
5’-GAGGTCAAGGGTCAAGCGAAGGTCACAAAGGACCTTGTCnGAGGACAATTAGAAGCGGACTCATTA
GGCAAGCACTTCCGGTGAACACATTACTATTACACCATCCACGCAAACCGAAGTCCAGCTAATGCTTTTCAGAGGAG
CCGACGTGCGCAGAAGCACATGCCAGCAAAGCCTCCAAGTCCAAACCATCCGAGCCCAACAAAGGGCTTAGGGTTTG
AGATTAACATGACACTCAAACAGGCATGCCCTTCGGAGTACCAAAGGGCGCAAGGTGCGTTCAAAGATTCGATGATT
CACTGAATTCTGCAATTCACATTACTTATCGCATTTCGCTGCGTTCTTCATCGATGCGAGAGCCAAGAGATCCGTTG
TTGAAAGTTGTATTAATTTTGCCCGCGAAGAGCAACACATTCACAAAACGTATAAAAGGTTGATAAAGATCAAAGCT
TTCAACCGCGCTCTTTTGAATGAAGGACATTCGCTCTCAGGCTACTTACGCTCGCACGCTTTCACCTTACTCACTAC
TGACCACCTTCAAACAATGAAACCCTTTCACTTTCAGGCGACCGGTGCTTACGCACGATCACCCTACTCATTACTAA
ATGCTTCAAAGAGTGTAGCCTACTTGCTTTGCAAAGG-3’。
It is further preferred that rRNA gene D1D2 region sequences (including the 28SrRNAD1-D2 sequences of the fontanesia leaf shelf fungus
Column-slice section) it is SEQ ID NO:2, it is as follows：
5’-TAGTAACTGCGAGTGAAGCGGGAAGAGCTCAAATTTGTAATCTGACGGTCCCTGGCTGTCCGAGTT
GTAATCTGTAGAGGCGTCGTCTGCGTCGGCCCGTGTACAAGTCTCCTGGAATGGAGCGTCATAGAGGGTGAGAATCC
CGTCCATGACACGGACCACCGATGCTCTGTGAGGTGCCCTCGAAGAGTCGCGTTGTTTGGGAATGCAGCGCAAAATG
GGTGGTAAATTCCATCTAAGGCTAAATATTGGCGAGAGACCGATAGCGAACAAGTACCGTGAGGGAAAGATGAAAAG
CACTTTGAAAAGAGAGTTAAACAGTACGTGAAATTGTTGAAAGGGAAACGCTTGAAGTCAGTCGTGTCTCGAGGCAC
TCAGCCTTGCTTTGGCTTGGTGTACTTGCCTTGGGATGGGTCAACATCAATTTTGGTCGGTGGATAAGGATGAGGGG
AATGTAGCGTTGTTTCGGCGACGTGTTATAGCCCCTTGTCGAATACGTCGACTGGGATTGAGGACTGCAGCACGCCC
TTGTGGCCGGGG-3’。
It is further preferred that the fontanesia leaf shelf fungus is the bracket fungus for being grown on fontanesia butt, 1 year or for many years
It is raw；Fructification cap-type, suberin；Cap length is up to 3.6cm, and wide up to 5.9cm, base portion is thick up to 0.6cm, and cap surface is by suede
Hair, yellowish-brown to dark brown, with concentricity, edge is sharp；Vent surface fawn has refractive power effect, no to yellowish-brown
Educate edge obvious；Aperture is circular, 10~12/mm, heavy wall, full edge；Mycelia monosystem type, generative hyphae tool is simple to be separated, colourless
To yellowish-brown, slightly heavy wall is to heavy wall, rare branch, loose interleaved arrangement, wide 1.9~3.7 μm, the wide ellipse of spore, 2.3~
3.1 × 1.9~2.4 μm, surface is smooth, light yellow, heavy wall.
Preferably, in terms of weight percent content, the fontanesia leaf shelf fungus is included：It is soluble polysaccharide 39~40%, thick
Protein 19~20%, crude fat 6~7%, crude fibre 10~11%, triterpene 1~1.5%.In addition, the fontanesia leaf shelf fungus is also
Comprising：Moisture 9~15%, ash content 4~6%, other organic components 8~10%.
It is highly preferred that in terms of weight percent content, the fontanesia leaf shelf fungus is included：It is soluble polysaccharide 39.4%, thick
Protein 19 .3%, crude fat 6.4%, crude fibre 10.3%, triterpene 1.1%.In addition, the fontanesia leaf shelf fungus is also included：Water
Divide 9.8%, ash content 5.3%, other organic components 8.4%.
The fontanesia leaf shelf fungus of the present invention is found in the autumn in 2015 in In Shandong Weihai area of Wendeng City and after chorista
Obtained strain is cultivated in PDA culture medium.
The fungal extract that the present invention is provided, is to extract to obtain by raw material of above-mentioned fontanesia leaf shelf fungus.
The epiphyte composition that the present invention is provided, contains above-mentioned fontanesia leaf shelf fungus or above-mentioned fungal extract.
The present invention provides the fontanesia leaf shelf fungus, fungal extract or epiphyte composition and is preparing prevention and/or controlling
Treat the purposes in medicine, health products, food, drink or the tea of tumour or raising immunity.
Preferably, the tumour includes andrology's tumour, gynecological tumor, tumor in respiratory system, digestive system tumor, urinary system
System tumour, dept. of dermatology's tumour, ENT dept.'s tumour, hematology's tumour, orthopaedics tumour, neurology department's tumour and department of general surgery's tumour.
More preferably and specifically, the tumour include breast cancer, intestinal cancer (including colon cancer and carcinoma of the rectum), lung cancer, stomach cancer,
Cancer of the esophagus, thyroid cancer, liver cancer, cervical carcinoma, carcinoma of urinary bladder, uterine cancer, kidney, lymph cancer, the cancer of the brain, prostate cancer, oophoroma, nose
Each position cancer of the whole bodies such as cancer, leukemia, tracheocarcinoma, bronchiolar carcinoma, laryngocarcinoma, cancer of pancreas, gallbladder cancer and osteocarcinoma.
Preferably, the medicine is tablet, decoction, capsule, granule, parenteral solution or freeze drying powder injection.
It will be understood by those skilled in the art that the fontanesia leaf shelf fungus will can be applied directly after raw material drying, crushing
Or be further prepared into formulation and applied such as capsule.
Preferably, the fontanesia leaf shelf fungus is extracted, obtains fungal extract, the fungal extract is further
The formulation that can be applied is prepared into together with pharmaceutically acceptable auxiliary material, is then applied.
The fungal extract, includes but is not limited to be prepared by the following method：
Fontanesia leaf shelf fungus and suitable quantity of water are mixed, then soaks and/or heats, filtering, nonessential concentration is produced true
Fungus extract；Or
Fontanesia leaf shelf fungus and appropriate solvent are mixed, then soaks and/or heats, filtering obtains extract solution, this is carried
Take liquid concentration, dry, produce fungal extract.
Preferably, the solvent is water, methanol, ethanol or its mixture.
Preferably, the fontanesia leaf shelf fungus is by drying in the shade or drying；Drying temperature is 40~90 DEG C.
Preferably, the fontanesia leaf shelf fungus is by crushing.
It will be understood by those skilled in the art that it is in order that the active component in get Xue Liuye shelf funguses is more prone to crush
Ground dissolution.
Fontanesia leaf shelf fungus of the present invention, fungal extract and epiphyte composition, are conceived to the regulation of general body state, righting is solid
This, can strengthen the immunologic function and resistance against diseases of tumor patient body.The present invention uses doctor trained in Western medicine chemotherapy, radiotherapy in the treatment with simple
Compare, have the characteristics that：
1st, the present invention is integration of drinking and medicinal herbs material from the fontanesia leaf shelf fungus, using safety, no obvious toxic-side effects.
2nd, the present invention has the effect for improving immunity of organisms, plays clearing heat and detoxicating, promoting blood circulation and removing blood stasis, softening and resolving hard mass, QI invigorating
The characteristics of taking care of health, suppress growth of tumour cell, improve organism metabolism balance, recover physical efficiency, mitigate patient suffering, using righting as
It is main, supplemented by eliminating evil, body healthy tendency is lifted, increases the sensitiveness and tolerance of chemotherapeutics, extends life span, matter of making the life better
Acted in amount notable.
Fontanesia leaf shelf fungus treatment tumour of the present invention has three principles of " help, prevent, controlling ".First, righting gas：Help patient's
Healthy tendency, improves the immunity of patient, repairs impaired immune deficiency.Second, prevent multiple turn：Relapse and metastasis is prevented, complication is prevented
Generation.3rd, control pathogeny：Prevent tumour cell from breeding, kill tumour cell." three principles " is to utilize fontanesia leaf shelf fungus
Unique pharmaceutical composition, the effective tumor therapeuticing method summed up with reference to cancer pathology feature.
Preservation explanation：W-001, Classification And Nomenclature：Fontanesia leaf shelf fungus (Phylloporia fontanesiae).Preservation list
Position：China Committee for Culture Collection of Microorganisms's common micro-organisms center.Preservation address：Beijing is Chaoyang District North Star West Road 1
Number No. 3 Institute of Microorganism, Academia Sinica of institute.Deposit number is：CGMCC No.11905.Preservation date：January 27 in 2016
Day.
Embodiment
The fontanesia leaf shelf fungus (latin name Phylloporia fontanesiae) of the present invention, is Basidiomycetes bracket fungus
A kind of fungi of section.Fontanesia leaf shelf fungus is New raxa, and former non-avaible introduces its application value.
The fontanesia leaf shelf fungus of the present invention has extensive pharmacological action, such as effect of antitumor action, protecting liver and detoxication, suppression
The effects such as cancer cell, raising body immunity.Chemical composition analysis shows that the soluble polysaccharide of fontanesia leaf shelf fungus of the present invention is
39~40%, crude protein is that 19~20%, crude fat is that 6~7%, crude fibre is that 10~11%, triterpene is 1~1.5%, moisture
It is that 4~6%, other organic components are 8~10% for 9~15%, ash content, especially, soluble polysaccharide is 39.4%, crude protein
It is that 6.4%, moisture is that 9.8%, crude fibre is that 10.3%, total triterpene is that 1.1%, ash content is 5.3% for 19.3%, crude fat,
Other organic components are 8.4%.
Wherein, determining the instrument used includes：
Energy dispersion X-ray energy disperse spectroscopy；Model：JSM-7500F
Ultraviolet spectrometer；Model：TU-1901
Kjeldahl apparatus；Model：K9840
Soxhlet fat extractor；Model：YLA-2000
Biomicroscope；Model：Shanghai XSP-8CA
Wherein, soluble polysaccharide and triterpenes have clear and definite antitumaous effect, and fontanesia leaf shelf fungus contains substantial amounts of solvable
Property polysaccharide and triterpenes components, therefore with immunological regulation, antitumor, anti-aging, activate blood circulation and disperse blood clots, anticoagulation, protect liver the effects such as, and
And suppress tumour cell growth or inducing apoptosis of tumour cell indirectly by strengthening immunity of organisms, it is effective to suppress tumour life
It is long, certain antitumor action is presented.
Fontanesia leaf shelf fungus of the present invention, fungal extract and epiphyte composition are used for the use for treating advanced malignant tumor
Method is：Adult is daily oral three times, also can be with other drugs every time equivalent to 5~500 grams of the fontanesia leaf shelf fungus of the present invention
It is applied in combination, every month is a course for the treatment of；Or drunk in tea form, it can be also applied in combination with other drugs, every month is one
The individual course for the treatment of.
The present invention is the understanding and principle of reatment to advanced malignant tumor based on traditional Chinese medicine, and hair is studied with reference to modern medicines
It is existing, formed through practice.Fontanesia leaf shelf fungus of the present invention, fungal extract and epiphyte composition by clearing heat and detoxicating, reducing phlegm and resolving masses,
QI invigorating takes care of health, the effect of atrophy tumour capillary, strengthens macrophages phagocytic capacity, adjusts immunity of organisms, improves appetite,
Enhancing physical efficiency improves symptom so as to play suppression growth of tumour cell, mitigates patient suffering, improves the work of patients ' life quality
With.
Found through clinical comparison：One is treated using fontanesia leaf shelf fungus of the present invention, fungal extract and epiphyte composition
After the course for the treatment of, compared with control group (applying chemotherapy and radiation), the Advanced cancers treatment total effective rate for the treatment of group of the invention is
94.3%, the total effective rate that control group is treated to Advanced cancers is 67.8%, and the total effective rate for the treatment of group is apparently higher than control
Group.
After the present invention is configured according to component, it can conventionally be fried into decoction of medicinal ingredients and take, routine side can also be used
Method manufactures Chinese medicine pill, instant particles as Chinese medicine and taken, can also according to the daily dosimetric system piece agent of Chinese herbal medicine, capsule,
Other the finished product modes that can take such as grain, medicine materical crude slice, powder.
By taking antitumor raising immunity as an example, fontanesia leaf shelf fungus of the present invention passes through clinical practice, and general patient medication 5~
Take effect within 10 days, slow takes effect for 15~20 days, symptom improves, pain relief.It is within one month a course for the treatment of, 1~8 course for the treatment of of medication
Have positive effect or rehabilitation, it is uneasy to recur after rehabilitation, another centering patients with terminal or should not perform the operation, the patient of chemicotherapy and postoperative
Relapse and metastasis person, also can reach therapeutic purposes.
Embodiment
Present invention is not limited to cited by embodiment, those of ordinary skill in the art by reading description of the invention and
Any equivalent conversion taken technical solution of the present invention, is that claim of the invention is covered.
Embodiment 1
Fontanesia leaf shelf fungus entity after harvesting dries in the shade after washing and cleaning, or is placed in drying, temperature control in barn
System is dried to fontanesia leaf shelf fungus water content 10% or so at 55~85 DEG C, deposits at shady and cool dry or fridge freshness retaining.Then will
Fontanesia leaf shelf fungus is crushed to more than 80 mesh, directly takes or every 20 Ke Xueliuye shelf funguses are advisable with about 1000 milliliters of water,
Plus-minus can be considered, immersion is preferred for 2~8 hours before infusion, and warm fire is boiled 25~30 minutes and is advisable after boiling；With form heat clothes of drinking tea.
Embodiment 2
Fontanesia leaf shelf fungus is selected, cleans, is placed in extractor, the water of 4~10 times of fontanesia leaf shelf fungus volumes is added
Extracted, Extracting temperature is 30~100 DEG C, and extraction time is 1~10 hour, is filtrated to get filtrate；Extract 1~4 time repeatedly,
Merge the filtrate filtered every time and obtain crude extract；
Crude extract is concentrated under reduced pressure on traditional Chinese drug inspissation pot, the pressure being concentrated under reduced pressure is -0.06~-0.08MPa, is steamed
It is 80~60 DEG C to send out temperature, is concentrated under reduced pressure into the medicinal extract that relative density is 1.35~1.40 (medicinal extract will control to survey at 50 DEG C)；
Medicinal extract and auxiliary material are put into mixer-granulator to mix, mixed by wetting agent of 65%~75% ethanol, stirring system
Wet granular is produced with the granulation of 14 eye mesh screens into softwood.
Wet granular feeding hot air circulation drying oven is dried, 60 DEG C~90 DEG C of drying temperature, about 6~8 hours drying times
(stirring once within every 2 hours).
By dry particl pelletizing machine with 8 mesh sieve whole grains, particle after whole grain is in selecting grain in shaking screen, screen cloth number is respectively
10 mesh and 80 mesh are the dry particle (detection moisture, granularity, melting and content) for obtaining fontanesia leaf shelf fungus；
Qualified particle is examined to be dispensed with automatic particle packing machine, loading amount (20 grams every bag), content uniformity ± 4.5%.
Embodiment 3
The fontanesia leaf shelf fungus 20g of drying is weighed, is prepared as follows：
A) add water 4~15 times of amounts for the first time, decocts 1~8 hour, adds water 10 times and measure for the second time, decocts 2 hours, merges medicine
Liquid, decoction filtration, takes filtrate, when being concentrated into relative density for 1.10~1.15 (60 DEG C), and adding ethanol reaches alcohol content
30%~80%, precipitation stands 24 hours, and Aspirate supernatant reclaims ethanol, obtains Aqueous extracts；
B) concentrate, dry, pulverize, get dry extract powder；
C) gained dried cream powder is fully mixed with appropriate amount of auxiliary materials, adhesive granulation is made with ethanol, dried, add appropriate amount of auxiliary materials
Mix, tablet is made.
Embodiment 4
The fontanesia leaf shelf fungus 30g of drying is weighed, is prepared as follows：
A) Jia 50%~9 times of 80% ethanol amount refluxing extractions twice, 1~4 hour for the first time, second 1~5 hour.Close
And decoction, decoction filtration, ethanol is reclaimed, alcohol extract is obtained；
B) dregs of a decoction after alcohol extracting are added water to cook twice jointly, are added water 15 times and are measured for the first time, are decocted 2 hours, are added water 8 for the second time
Times measure, decoct 2 hours, merge decoction, decoction filtration takes filtrate, be concentrated into relative density for 1.10~1.15 when (50 DEG C of surveys),
Adding ethanol makes alcohol content reach 40%~70%, and precipitation stands 12~36 hours, and Aspirate supernatant reclaims ethanol, obtains water extraction
Liquid；
C) gained alcohol extract and Aqueous extracts are merged, concentration dry, pulverize, get dry extract powder；
D) gained dried cream powder is fully mixed with appropriate amount of auxiliary materials, binder granulation is made with ethanol, dried, added appropriate auxiliary
Material is mixed, and loads capsule for medicine.
Case：
1st, it is high certain, female, 43 years old, because pain to examination in hospital is diagnosed as breast cancer, Post operation did 4 chemotherapy, recurrence expansion
Dissipate.Take 20 grams of fontanesia leaf shelf fungus, 1000 milliliters of water, according to drying, crushing, immersion, decoct after daily, examined after 5 months
Look into various indexs normal, existing Tumor invasion is normal, can be engaged in light physical labor.
2nd, it is tall certain, man, 65 years old, peasant, stomachache finds intestinal cancer through examination in hospital, and Post operation is put by more than ten times in two years
Chemotherapy, rear diffusion takes 20 grams of fontanesia leaf shelf fungus daily, 1500 milliliters of water, decocts after half an hour and to be drunk in tea form, 10
Tumor invasion disappears after month, can be engaged in light physical farm work.
3rd, certain is finished, 34 years old, examination in hospital is removed because often coughing by female, discovery advanced lung cancer, about egg size, due to position not
It is good, operative chance has been lost, about 15 grams of fontanesia leaf shelf fungus is taken daily, 1000 milliliters of water is decocted after half an hour in tea form
Drink.Tumor disappearance after about 6 months, normal life.
4th, Zhang, man, 67 years old, Nanjing retired employees of factory after Surgery for Gastric Carcinoma, took 25 grams of fontanesia leaf shelf fungus to match somebody with somebody daily
1000 milliliters of water, which are endured, to be done tea and drinks, and is drunk throughout the year, and based on light light food, after move to City by The Sea inhabitation, 35 years nothings
Recurrence.
5th, Lee, man, 42 years old, due to eating difficulties, hoarseness, examination in hospital was diagnosed as cancer of the esophagus, by putting for several times
Therapeutic effect is undesirable, the selection traditional Chinese medical science of having no alternative.50 grams of fontanesia leaf shelf fungus is taken daily, according to clothes after drying, crushing, immersion, decoction
With inspection finds incorporeity tumour after 6 months, and index is normal, can normal work.
6th, flood certain, female, 39 years old, due to feeling nervous, become thin, it is weak, and then there is hoarseness, expiratory dyspnea is isobaric
Compel symptom, thyroid cancer is diagnosed as through examination in hospital.Take 20 grams of fontanesia leaf shelf fungus daily, according to drying, crushing, immersion, decoct
Taken after boiling, somatosensory is pleasant after two months, quality of life is significantly improved, tumor disappearance after 8 months.
7th, Zhang, man, 32 years old, liver cancer handled postoperative recurrence, has carried out multiple in 7 PCIs, liver and has been diffused into again
Lung, maximum tumour is more than 10cm, and hospital abandons treatment.Take 25 grams of fontanesia leaf shelf fungus daily, according to drying, crushing, immersion,
Taken after decoction, tumour is reduced to 3.5cm or so after 8 months, and the madam of Zhang gives birth to 3.9 kilograms of boy, Mu Zijian after 1 year
Health.Zhang's symptom has clear improvement, and pain over the chest and back stops, and can be engaged in light physical labor.
8th, palace, female, 51 years old, there is colporrhagia again in post menopausal, found that cervical surfaces are smooth or are in during gynecologial examination
Hard, the tactile easy bleeding of rotten to the corn shape, matter, is diagnosed as cervical carcinoma.It is invalid after three chemotherapy, 25 grams of fontanesia leaf shelf fungus is taken daily, is pressed
According to drying, crushing, immersion, decoct after take, symptom mitigation after one month, incorporeity knurl, is as good as with ordinary person after 6 months.
9th, 57 years old, carcinoma of urinary bladder, radiotherapy effect are diagnosed as due to there is blood urine to have a surplus within two months to examination in hospital by Liu, man
Fruit is not obvious.20 grams of fontanesia leaf shelf fungus is taken daily, according to being taken after drying, crushing, immersion, decoction, separately coordinates other drugs,
Weight ratio is：Each 30 grams of the dried rhizome of rehmannia, Chinese yam, 12 grams of mountain cornel, each 30 grams of Poria cocos, umbellate pore furgus Asian puccoon, 6 grams of aloe, field thistle, charred POLLEN TYPHAE each 12
Gram, Sculellaria barbata, spend in vain tongue grass it is each 30 grams.Daily 1 dose, it is decocted in water for oral dose.Blood urine is gradually decreased after one month, incorporeity knurl after 7 months,
Tumor invasion is normal, can be engaged in light physical work.
10th, Zhang, female, 43 years old, pain and uterine hemorrhage were diagnosed as uterine cancer, Post operation diffusion, through four through examination in hospital
It is in poor health after secondary chemotherapy, 20 grams of fontanesia leaf shelf fungus is taken daily, according to drying, crushing, immersion, decoct after take, body by
Gradually take a turn for the better, incorporeity knurl after 7 months, Tumor invasion is normal.
11st, car, man, 52 years old, Low Back Pain, band blood, has the symptoms such as weak, weight loss, poor appetite, is examined through hospital in urine
Look into and be diagnosed as kidney, recurrence after operation and liver, retroperitoneal lymph node transfer bladder.22 grams of fontanesia leaf shelf fungus is taken daily, according to
Taken after dry, crushing, immersion, decoction.Bland diet, checks incorporeity knurl after 10 months, Tumor invasion is normal.
12nd, Lee, man, 51 years old, cough, uncomfortable in chest, shortness of breath, lung rose, and lymph cancer, 5 treatments of chemotherapy are diagnosed as to examination in hospital
There are the debilitated state of extreme and serious Chemotherapy Complications in journey, body, and 20 grams of fontanesia leaf shelf fungus is taken daily, according to drying,
Taken after crushing, immersion, decoction, it is normal to the various indexs of examination in hospital after 1 year, light physical labor can be engaged in.
13rd, Zhang, man 37 years old, because examination in hospital is arrived in headache, vomiting, is diagnosed as the cancer of the brain, and effect is failed to understand after chemotherapy three times
It is aobvious, 20 grams of fontanesia leaf shelf fungus is taken daily, according to being taken after drying, crushing, immersion, decoction, separately coordinates other drugs, weight ratio
For：10 grams of the calyx and receptacle of a persimmon, 3 grams of cloves, 5 grams of ginger.It is decocted in water for oral dose, daily 1 dose, point 2 clothes.Incorporeity knurl, tumour are checked after 10 months
Index is normal.
14th, Zhao, man, 63 years old, because dysuria, the retention of urine, pain, blood urine to examination in hospital are diagnosed as prostate cancer,
Chinese traditional treatment is changed to after radiotherapy twice because health is poor, 27 grams of fontanesia leaf shelf fungus is taken daily, according to drying, crushing, leaching
Taken after bubble, decoction, incorporeity knurl is checked after 8 months, Tumor invasion is normal.
15th, Zhang, female 54 years old, has found that oophoroma and ascites are serious because stomachache is checked, after done 5 chemotherapy, snow is taken daily
22 grams of willow leaf shelf fungus, according to drying, crushing, immersion, decoct after take, in consanguinity examination in hospital after 5 months, basic convergence
Normally.
16th, Mr. Wang, male, 58 years old, Chu's object is not seen because eyes are fuzzy, to examination in hospital after find rhinocarcinoma late period, continuously
Rejected by two Grade A hospitals, reason is, without therapeutic potential, to take 23 grams of fontanesia leaf shelf fungus daily afterwards, according to drying, crushing, leaching
Take, vision restoration is normal after one month, to examination in hospital is once rejected, find without tumour, doctor is surprised after bubble, decoction, then
It is secondary to be checked, confirm incorporeity tumour, manual labor can be engaged in, rear interruption is taken, physical rehabilitation.
17th, Zheng, female, 23 years old, because of headache vomiting, gum swelling, body pain to examination in hospital was diagnosed as leukemia, four changes
It is in poor health after treatment, 25 grams of fontanesia leaf shelf fungus is taken daily, according to being taken after drying, crushing, immersion, decoction, separately coordinates other
Medicine, weight ratio is：30 grams of the Radix Astragali, 20 grams of radix pseudostellariae, 15 grams of sealwort, 12 grams of the bighead atractylodes rhizome, 10 grams of Poria cocos, 20 grams of the dried rhizome of rehmannia, the tuber of dwarf lilyturf 20
Gram, 15 grams of asparagus fern, 18 grams of Eclipta prostrata, 15 grams of the fruit of glossy privet, 30 grams of oldenlandia diffusa, 30 grams of Sculellaria barbata, 30 grams of dandelion, field thistle 15
Gram, 5 grams of radix glycyrrhizae.It is decocted in water for oral dose, daily 1 dose, takes day 2 times.The various indexs of body are normal after 8 months, are as good as with ordinary person.
18th, Mr. Wang, male, 62 years old, cough for many years, found laryngocarcinoma after inspection, and post-surgical chemotherapy is once, rear to feel chemotherapy pair
The big refusal of effect, takes 15 grams of fontanesia leaf shelf fungus to endure water, often eats and drink 1/3rd after meal, continuously drink half a year daily, after once in a while
Drink, the various indexs of body are normal, without recurrence, live without influence within 11 years.
19th, it is high certain, man, 43 years old, indigestion, appetite was bad, Body weight loss and along with pain, was made a definite diagnosis through examination in hospital
For cancer of pancreas, open and find to cut off after abdomen, give pass abdomen expectant treatment, take 25 grams of fontanesia leaf shelf fungus daily afterwards, according to dry
Taken after dry, crushing, immersion, decoction, separately coordinate other drugs, weight ratio is：15 grams of radix bupleuri, 25 grams of oriental wormwood, 15 grams of Ramulus euonymi,
30 grams of desmodium, 12 grams of grub, 20 grams of bittersweet, raw 6 grams of Sichuan troops' (under rear), 12 grams of the dried immature fruit of citron orange, 15 grams of the bark of official magnolia, 10 grams of pillworm, the banksia rose
15 grams, kowtow 15 grams of benevolence in vain, each 15 grams of Charred Triplet, 20 grams of tiger battle, 20 grams of one portion per day of akebiae, add water 2000-2500ml, leaching
Bubble 2 hours, decocts to 200ml, residue obtained liquid, respectively takes 100ml sooner or later.Various indexs are normal after 11 months, live without influence.
20th, Lee, female, 66 years old, because upper abdomen rest pain to examination in hospital is diagnosed as gallbladder cancer, post-surgical chemotherapy
After three times spread, take 25 grams of fontanesia leaf shelf fungus daily afterwards, according to drying, crushings, immersion, decoction after take, 10 months future troubles
The various indexs of person are normal, can be engaged in simple work.
21st, Zheng, man, 13 years old, because femur handicapped go to see a doctor that have an intense pain is diagnosed as osteocarcinoma, family members were apprised of
Situation is serious, and days are numbers, needs to cut off whole lower limb and pelvis if performing an operation, then carries out chemotherapy, and prognosis is not good, and entirely
Therapeutic process dangerous, expense is hard to predict, and patient will also bear huge pain.Take 25 grams of fontanesia leaf shelf fungus daily afterwards, press
According to being taken after drying, crushing, immersion, decoction, separately coordinate other drugs, weight ratio is：20 grams of radix pseudostellariae, 30 grams of the Radix Astragali, the bighead atractylodes rhizome
10 grams, 12 grams of Poria cocos, 6 grams of dried orange peel, 12 grams of sealwort, 30 grams of reticulate millettia, 15 grams of the root of herbaceous peony, 10 grams of barrenwort, 12 grams of cultivated land, malt 15
Gram, 15 grams of oldenlandia diffusa.It is decocted in water for oral dose, daily 1 dose, takes day 2 times.Things are as usual for patient's life after 6 months, can voluntarily walk,
Without special discomfort, herbal treatment, to consolidate curative effect, prevents recurrence once in a while.
22nd, Sun, female, 49 years old, peasant；Because right breast finds a lump 2 months and goes to a doctor.Readme was not intended to before 2 months
Middle discovery right breast has a small lump, without pain, therefore does not take notice of.It has recently found that lump constantly increases, skin of breast swelling,
Come to go to a doctor, be diagnosed as breast cancer.Take 20 grams of fontanesia leaf shelf fungus daily afterwards, 1000 milliliters of water, according to drying, crushing, immersion,
Taken daily as tea after decoction, check that various indexs are normal after 6 months, Tumor invasion is normal.
23rd, Lee, female, 33 years old, company worker, physical examination found that Tumor invasion is abnormal, and then inspection is diagnosed as breast cancer, by
In the breast cancer history for having familial inheritance, patient's mood is very unstable, and chemotherapy effect is not good, takes fontanesia leaf layer hole daily afterwards
25 grams of bacterium, 800 milliliters or so of water, according to drying, crushing, immersion, decoct after daily, various index bases are checked after 5 months
This is normal, can normal work.
24th, Wu, female, 44 years old, Mammary cancer 10 months was found multiple when being checked after 3 months, 1 year after end of chemotherapy
Hair, takes 25 grams of fontanesia leaf shelf fungus daily afterwards, 1000 milliliters or so of water, according to after drying, crushings, immersion, decoction daily,
Check that various indexs are normal after 8 months.
25th, Liu, man, 57 years old, be colon cancer because persistently there is bloody stool by hospital diagnosis, postoperative physical recovery is obtained very well,
Originally think from this and tormented away from cancer, after 1 year, discontinuity pain occurs in Right Lower Abdomen, and the state of mind is poor than before, hospital's check
After be diagnosed as cancer patients Intrahepatic metastasis.Take 22 grams of fontanesia leaf shelf fungus daily afterwards, 1000 milliliters or so of water, according to drying,
After crushing, immersion, decoction daily, check that various indexs are normal after 6 months, B ultrasound check is shown in liver normally, is not sent out
Existing low echo group.
26th, Mr. Wang, male, 45 years old, be the carcinoma of the rectum through hospital diagnosis, through half a year chemotherapy physical rehabilitation after operation, afterwards for a long time not
Check, 2 years processus aboralis sense upper abdomen severe pain, rest can not also be alleviated, and find a huge focus through super check of hospital, finally make a definite diagnosis
For carcinoma of the rectum hepatic metastases.Take 25 grams of fontanesia leaf shelf fungus daily afterwards, 1000 milliliters or so of water according to drying, crushing, immersion, is decocted
After boiling daily, the state of an illness gradually mitigates, muscle power increase, checks that various indexs are normal after 1 year, and B ultrasound check display is without reality
Body knurl.
27th, 77 years old, upper left adenocarcinoma of lung, the multiple transfer of two lungs are made a definite diagnosis through hospital by Yuan, female.Take fontanesia leaf layer hole daily afterwards
20 grams of bacterium, 1000 milliliters or so of water, according to drying, crushing, immersion, decoct after daily, after about 10, the cough symptom such as sulks
Substantially mitigate.Symptom is wholly absent after 3 months, and physical state recovers normal, and chest CT shows that primary tumor and transfer stove have bright
It is aobvious to reduce.CT is checked after 10 months again, tumour is close to be wholly absent.
28th, Zhang, man, 70 years old, cough, drenching with rain to suffer from cold starts cough of sneezing, and half sound dry cough continues 6 wheat harvesting periods.After cough
Coughing becomes frequent, hence it is evident that aggravate, expectoration of blood streaked sputum.One 2 centimeters of lymph node is touched during to examination in hospital on right clavicle, is done
Supraclavicular lymph nodes is punctured, and smear finds metastasis cancer cell.Apply for a supraclavicular lymph nodes biopsy again, pathological replacement, which is shown, to be turned
Shifting property squamous carcinoma, SABC prompting derives from lung.Take 25 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to dry daily afterwards
After dry, crushing, immersion, decoction daily, the state of an illness gradually mitigates, and incorporeity knurl after 10 months, various indexs are normal.
29th, certain is taken, man, 60 years old, because uncomfortable in chest cough makes a definite diagnosis lung cancer through hospital, upper abdomen CT was unenhanced：The multiple metastatic tumor of liver
With a small amount of ascites.Chest CT scans：Leaf occupy-place indulges diaphragm, both sides oblique segmentation pleura, multiple chest rib, thoracic vertebrae and the right side with upper left on two lungs
Multiple slightly larger lymph node in side omoplate Bone tumour, both sides hilus pulumonis, vertical diaphragm；Both sides pleura is invaded with a small amount of hydrops in both sides, upper left lung
The multiple transfer of ED-SCLC.Take 25 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to drying, crushing, leaching daily afterwards
After bubble, decoction daily, the state of an illness gradually mitigates, through CT scan incorporeity knurl after 1 year, and various indexs are normal, can be engaged in simple
Work activity.
30th, still certain, female, 53 years old, apocleisis was vomitted sometimes, and vomiting number is cumulative, the symptoms last such as upper abdomen pain three
Month go examination in hospital to be diagnosed as stomach cancer, since the above-mentioned symptom since, weight loss 10kg.Feel abdominal distension, tired out powerless after the meal
And lassitude.Given up smoking before having smoking history, 20/day, but 4 years.There are drink hobby, 30g/ days.Take fontanesia leaf layer daily afterwards
20 grams of pore fungi, 1000 milliliters or so of water, according to drying, crushing, immersion, decoct after take after the meal daily, the state of an illness is gradually after January
Mitigate, incorporeity knurl after half a year can be engaged in simple housework.
31st, Liao, female, 78 years old, because apocleisis pain to hospital is diagnosed as stomach cancer.Because of advanced in age, the traditional Chinese medical science of seeing a doctor.Quarter examines：
Lean and haggard, pin is soft weak, likes warm-served food, and difference of sleeping, 2~3 days a line of defecating, onyx is simple and unadorned, and red tongue with thin fur, arteries and veins delays.Take daily afterwards
25 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water is taken, one according to daily tea form after drying, crushing, immersion, decoction
The state of an illness gradually mitigates after month, and incorporeity knurl after half a year, various indexs are normal.
32nd, Tan, man, 23 years old, a singing-hall do waiter, almost every night 11 points more to roast stand eat barbecue,
Have the beer.It is continuous afterwards to feel that pain malaise symptoms occurs suddenly in upper abdomen, and increasingly become thin, it is diagnosed as stomach cancer evening through examination in hospital
Phase.Take 24 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to daily tea after drying, crushing, immersion, decoction daily afterwards
Form is taken, and the state of an illness gradually mitigates after January, and incorporeity knurl after half a year, various indexs are normal.
33rd, Mr. Wang, male, 42 years old, because of its dysphagia, goes local hospital diagnosis and treatment.CT examination is found under its esophagus afterwards
It is cancer of the esophagus that biopsy pathology is taken under the section big lesser tubercles of one 3 × 4.5cm, oesophagoscope.Therefore row radiotherapy 30 times, dysphagia is delayed after treatment
Solution, check focus is contracted to 0.5cm sizes.Found when being checked after half a year at Lung metastases 2, size about 3 × 5 × 2cm, 2 × 3cm knot
Section, while finding still to feel that abdominal distension is uncomfortable, takes 25 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to drying, powder daily afterwards
Daily tea form is taken after broken, immersion, decoction, and gradually spiritual appetite takes a turn for the better, and tumour is gradually reduced, incorporeity knurl after 9 months,
Various indexs are normal.
34th, Lv, man 54 years old, because of dysphagia, swallows saliva chest pain.After doing esophoagoscopy to hospital, it is diagnosed
There are 2.3cm malignant tumours for Esophageal Middle Segment.Take 20 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to drying, powder daily afterwards
Daily tea form is taken after broken, immersion, decoction, and the state of an illness gradually mitigates, and incorporeity knurl is checked after half a year, and various indexs are normal,
Light physical labor can be engaged in.
35th, Meng, man, 65 years old.Suffer from thyroid cancer late period, done thyroid gland and cut art and Neck Dissection entirely, it is postoperative
Receive radiotherapy, operation and radiotherapy sequelae are serious, have a strong impact on patient's normal life, rear recurrence, hoarseness, aspirant, neck
Tight beam sense, swelling, local symptom is serious, and neck shoulder is numb, dizzy, headache, patients ' life quality degradation, anxiety, and pain is not
May.Take 25 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to daily tea after drying, crushing, immersion, decoction daily afterwards
Form is taken, and sound has been clearly better during patient's further consultation after two weeks, lifts up one's voice and has felt light.The state of mind is clearly better, 3
Patient's symptom substantially mitigates after month, and quality of life is significantly improved, and check blood examination is normal.
36th, Xiao, female 52 years old, until in December, 2013, has found the low echo nodules of right lobe of thyroid gland, greatly through examination in hospital
Small is 1.2 × 1.2 × 1.2cm；It is admitted to hospital thyroid nodule aspiration biopsy, pathological replacement shows thyroid cancer, after hospital surgical
Recurrence, takes 20 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to daily tea after drying, crushing, immersion, decoction daily afterwards
Water form is taken, and the state of an illness gradually takes a turn for the better, and incorporeity knurl after half a year, various indexs are normal.
37th, Lee, female, 47 years old, because voice is hoarse suddenly, treatment was diagnosed as thyroid cancer, expert after having no resolution from new inspection
Post operation, it is contemplated that two to three moons of life cycle, because postoperative health is not good, refuses further chemotherapy recurrence, takes daily afterwards
20 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water is taken, disease according to daily tea form after drying, crushing, immersion, decoction
Feelings are gradually taken a turn for the better, and incorporeity knurl is checked after three months, check that various indexs are normal after half a year, can be engaged in the housework such as cook, do washing
Activity.
38th, Zhao, man, 54 years old, through having the malignant tumour of 1 × 1.5 × 1.2cm sizes in examination in hospital liver and gall, and belongs to
Poor differentiated carcinoma, many reactions of Post operation：Wound pain, cough, seroperitoneum, symptomatic ulcer etc., postoperative a year and a half cancer are thin
The right liver relapse and metastasis of born of the same parents.His body may be allowed most probably to hold if re-treatm ent to can't stand.Take fontanesia leaf layer hole daily afterwards
25 grams of bacterium, 1000 milliliters or so of water is taken, the state of an illness gradually takes a turn for the better according to daily tea form after drying, crushing, immersion, decoction,
Check that various indexs are normal after half a year, incorporeity knurl is as good as with ordinary person.
39th, Gong, man is 52 years old, weak because of hepatalgia, and the symptom such as heating is diagnosed as Primary Hepatic to examination in hospital
Cancer, 8.86 × 9.45cm of Tumor size carries out surgery excision, and postsurgery symptoms do not subtract, increased weight on the contrary.There is anorexia, abdominal distension
Discomfort, aggravates after meal, weak, becomes thin, right Upper abdominal pain, in shouting pain.Check finds recurrence after three months, takes fontanesia leaf daily afterwards
20 grams of shelf fungus, 1000 milliliters or so of water is taken, the state of an illness is gradually according to daily tea form after drying, crushing, immersion, decoction
Take a turn for the better, patient's hepatalgia mitigates, spirit has taken a turn for the better, appetite increase, body weight is also increased much, and various symptoms are substantially
Through disappearing, the lump in liver disappears on inspection, and stable disease is in high spirits, and skin is ruddy, substantially steady by the situation of reviewing patient
It is fixed.
40th, 40 years old, there is colporrhagia before half a year, occurs leucorrhea increasing later and with stench, through hospital's phase in seedling, female
Close and check.Gynecologial examination shows that patient's severe cervical erosion is outstanding, with a small amount of oozing of blood, uterus normal size, palace side group
Knit soft, no tenderness, double accessory Non Apparent Abnormality.Pelvic cavity magnetic resonance imaging shows, uterine cancer.Cervical biopsy shows " low differentiation squama
Shape cell cancer ".Take 20 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to every after drying, crushing, immersion, decoction daily afterwards
Day, tea form was taken, and the state of an illness gradually takes a turn for the better, and various indexs are normal after half a year, and incorporeity knurl can normal work.
41st, Liu, female 35 years old, marries for 19 years old, and be pregnant 4 fertilities, 1 child, after because of the same branch of a family bleeding, amount is few, and color is red, in vain
Many, the yellow of band, has peculiar smell, patient identifies oneself without exception, and rear Irregular vagina bleeding simultaneously has right side pain in the back, and discovery palace is checked to institute
Right side iliopsoas, ilium, pyriformis, gluteus minimus are simultaneously invaded in neck cauliflower-shaped tumour, transfer uterus side, diagnosing cervical late period,
Operative chance is lost, therapeutic scheme can only use radiotherapy+chemotherapy, and therapeutic effect is poor.Take fontanesia leaf shelf fungus 20 daily afterwards
Gram, 1000 milliliters or so of water, according to drying, crushing, immersion, decoct after daily tea form take, checked after 10 months without
Solid tumor, various indexs are normal.
42nd, Mr. Wang, male, 56 years old, because hematuria, dysuria are diagnosed as " carcinoma of urinary bladder " in local hospital physical examination, and in doctor
Institute carries out surgery excision and chemicotherapy.Postoperative one-year age, is shown in blood urine again, and with pain in the back symptom.Household will be sent to doctor immediately
Institute is checked, and is diagnosed as " the postoperative Lymph Node Metastasis of carcinoma of urinary bladder, pelvic cavity transfer ".Take 20 grams of fontanesia leaf shelf fungus, water daily afterwards
1000 milliliters or so, taken according to daily tea form after drying, crushing, immersion, decoction, after two months, Mr. Wang foot edema
Take a turn for the better, free movement of the bowels, numbness of lower limbs takes a turn for the better, and can alone go out and have a walk, no significant discomfort.Check again, abdominal aorta and under
Shown portion shows no obvious abnormalities enlarged lymph node around chamber, and double kidneys are shown no obvious abnormalities.Serum Indexes are in normal range (NR)
Within.
43rd, certain is taken, man, 61 years old.Occur blood urine in half a year repeatedly 7-8 times, always continue 3-4 talent every time and die down,
Found through examination in hospital：Beside bladder left side wall is at the tubal bladder opening of left side, have diameter about 2cm's swollen
Block, dashes forward into bladder cavity.Make pathologic finding, be as a result reported as carcinoma of urinary bladder.Recurrence after operation, takes fontanesia leaf shelf fungus 25 daily afterwards
Gram, 1000 milliliters or so of water, according to drying, crushing, immersion, decoct after daily tea form take, the state of an illness is gradually after one month
Alleviate, incorporeity knurl after half a year, various indexs are normal.
44th, poplar, female, 59 years old.Because unregular vaginal bleeding is with the day of lower abdomen distending pain more than 40, confirm through hospital's section pathology
Carcinoma of endometrium.Because patient in poor health have rejected operation, 20 grams of fontanesia leaf shelf fungus is taken daily afterwards, 1000 milliliters or so of water,
Taken according to daily tea form after drying, crushing, immersion, decoction, the state of an illness is gradually alleviated after one month, incorporeity after half a year
Knurl, various indexs are normal.
45th, Luo, female 57 years old, because Irregular vagina bleeding to examination in hospital is diagnosed as carcinoma of endometrium, after in hospital
Treat 5 times, radiotherapy is in hospital after one week, three months because of bleeding again, and find that surrounding tissue has a transfer, but chemotherapy is imitated for three times
Fruit is not obvious, the sense of lower abdomen falling inflation and jump pain.Take 20 grams of fontanesia leaf shelf fungus, 1000 milliliters or so of water, according to drying, powder daily afterwards
Daily tea form is taken after broken, immersion, decoction, and the state of an illness is gradually alleviated after one month, incorporeity knurl after half a year, and various indexs are just
Often.
Claims (10)
1. a kind of fontanesia leaf shelf fungus, the entitled Phylloporia fontanesiae of the bacterium Latin, were protected on January 27th, 2016
China Committee for Culture Collection of Microorganisms's common micro-organisms center is hidden in, deposit number is：CGMCC No.11905.
2. fontanesia leaf shelf fungus according to claim 1, it is characterised in that the fontanesia leaf shelf fungus includes 18S
RRNA fragments, ITS1,5.8S rRNA, ITS2 complete sequence and the rRNA gene ITS region sequences of 28S region sequence fragments are SEQ
ID NO:1。
3. fontanesia leaf shelf fungus according to claim 1, it is characterised in that the fontanesia leaf shelf fungus includes 28S
The rRNA gene D1D2 region sequences of rRNAD1-D2 sequence fragments are SEQ ID NO:2.
4. fontanesia leaf shelf fungus according to claim 1, it is characterised in that the fontanesia leaf shelf fungus is to be grown on fontanesia
The bracket fungus of butt, 1 year or perennial；Fructification cap-type, suberin；Cap length is wide up to 5.9cm up to 3.6cm,
Base portion is thick up to 0.6cm, and cap surface is by fine hair, yellowish-brown to dark brown, and with concentricity, edge is sharp；Vent surface is shallow
Yellowish-brown has refractive power effect to yellowish-brown, and sterile edge is obvious；Aperture is circular, 10~12/mm, heavy wall, full edge；Mycelia is single
It is type, generative hyphae tool is simple to be separated, and colourless to arrive yellowish-brown, slightly heavy wall is to heavy wall, rare branch, and loose interleaved arrangement is wide by 1.9
~3.7 μm, the wide ellipse of spore, 2.3~3.1 × 1.9~2.4 μm, surface is smooth, light yellow, heavy wall.
5. fontanesia leaf shelf fungus according to claim 1, it is characterised in that in terms of weight percent content, the fontanesia
Leaf shelf fungus is included：Soluble polysaccharide 39~40%, crude protein 19~20%, crude fat 6~7%, crude fibre 10~11%, three
Terpene 1~1.5%.
6. a kind of fungal extract, it is characterised in that the fungal extract is to extract to obtain by raw material of fontanesia leaf shelf fungus.
7. a kind of epiphyte composition, it is characterised in that the epiphyte composition contains the snow described in any one of Claims 1 to 5
Fungal extract described in willow leaf shelf fungus or claim 6.
8. fungal extract or power described in fontanesia leaf shelf fungus according to any one of claims 1 to 5, claim 6
Profit requires that the epiphyte composition described in 7 is preparing prevention and/or treatment tumour or the medicine, health products, the food that improve immunity
Purposes in product, drink or tea.
9. purposes according to claim 8, it is characterised in that the tumour includes andrology's tumour, gynecological tumor, breathing system
Unite tumour, digestive system tumor, Patients with Urinary System Tumors, dept. of dermatology's tumour, ENT dept.'s tumour, hematology's tumour, orthopaedics tumour, god
Through section's tumour and department of general surgery's tumour；Preferably, the tumour includes breast cancer, intestinal cancer, lung cancer, stomach cancer, cancer of the esophagus, thyroid gland
Cancer, liver cancer, cervical carcinoma, carcinoma of urinary bladder, uterine cancer, kidney, lymph cancer, the cancer of the brain, prostate cancer, oophoroma, rhinocarcinoma, leukemia, tracheae
Cancer, bronchiolar carcinoma, laryngocarcinoma, cancer of pancreas, gallbladder cancer and osteocarcinoma.
10. the purposes according to any one of claim 8~9, it is characterised in that the medicine is tablet, decoction, capsule
Agent, granule, parenteral solution or freeze drying powder injection.
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| CN101481658A (en) * | 2008-10-13 | 2009-07-15 | 中丹康灵（北京）生物技术有限公司 | Novel production process of Ganoderma lucidum mycelium powder |
| CN105219657A (en) * | 2015-10-22 | 2016-01-06 | 江苏安惠生物科技有限公司 | Rainbow conk liquid fermenting high polysaccharide bacterial strain and selection thereof |
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