CN102282464B - 逆流色谱转子 - Google Patents

逆流色谱转子 Download PDF

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Publication number
CN102282464B
CN102282464B CN200980154785.5A CN200980154785A CN102282464B CN 102282464 B CN102282464 B CN 102282464B CN 200980154785 A CN200980154785 A CN 200980154785A CN 102282464 B CN102282464 B CN 102282464B
Authority
CN
China
Prior art keywords
counter
current chromatograph
helical
tubing
current
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200980154785.5A
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English (en)
Chinese (zh)
Other versions
CN102282464A (zh
Inventor
玛莎·奈特
托马斯·芬恩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CC Biotech LLC
Original Assignee
CC Biotech LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CC Biotech LLC filed Critical CC Biotech LLC
Publication of CN102282464A publication Critical patent/CN102282464A/zh
Application granted granted Critical
Publication of CN102282464B publication Critical patent/CN102282464B/zh
Expired - Fee Related legal-status Critical Current
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/42—Flow patterns using counter-current
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0402—Cleaning, repairing, or assembling

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Centrifugal Separators (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
CN200980154785.5A 2008-11-18 2009-11-18 逆流色谱转子 Expired - Fee Related CN102282464B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19958708P 2008-11-18 2008-11-18
US61/199,587 2008-11-18
PCT/US2009/064976 WO2010059715A2 (en) 2008-11-18 2009-11-18 Countercurrent chromatography rotor

Publications (2)

Publication Number Publication Date
CN102282464A CN102282464A (zh) 2011-12-14
CN102282464B true CN102282464B (zh) 2015-08-26

Family

ID=42198786

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980154785.5A Expired - Fee Related CN102282464B (zh) 2008-11-18 2009-11-18 逆流色谱转子

Country Status (6)

Country Link
US (2) US8597509B2 (enExample)
EP (1) EP2366104B1 (enExample)
JP (2) JP5695572B2 (enExample)
KR (1) KR101717302B1 (enExample)
CN (1) CN102282464B (enExample)
WO (1) WO2010059715A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201115218D0 (en) 2011-09-02 2011-10-19 Glaxo Group Ltd Novel process
US9636871B2 (en) * 2013-08-21 2017-05-02 Microsoft Technology Licensing, Llc Optimizing 3D printing using segmentation or aggregation
US20180126298A1 (en) * 2015-05-22 2018-05-10 Merck Patent Gmbh Device for substance separation
US11065601B2 (en) 2015-12-18 2021-07-20 University Of Canterbury Separation medium
CN105628831A (zh) * 2016-03-10 2016-06-01 山东省分析测试中心 一种3d打印的逆流色谱分离柱以及色谱仪
CN105651911A (zh) * 2016-03-10 2016-06-08 山东省分析测试中心 一种新型的逆流色谱分离柱以及色谱仪
DE102016222376B3 (de) * 2016-11-15 2018-02-15 Zf Friedrichshafen Ag Elektronikmodul und Verfahren zum Herstellen desselben
WO2018098505A1 (en) * 2016-11-28 2018-05-31 Massachusetts Institute Of Technology Vacuum pumps and methods of manufacturing the same
US10851349B1 (en) 2018-02-28 2020-12-01 Cc Biotech Llc Virus purification
CN108717092B (zh) * 2018-05-17 2024-04-05 四川大学 一种β值可变式高速逆流色谱仪及其控制方法
WO2020127252A1 (en) * 2018-12-20 2020-06-25 Merck Patent Gmbh Method for providing a casing for a chromatography column and chromatography column
US20220152523A1 (en) * 2019-03-02 2022-05-19 Martha Knight Cannabinoid Separation by Countercurrent Chromatography
US11911719B2 (en) * 2019-09-20 2024-02-27 Massachusetts Institute Of Technology Devices and methods for the integrated filtration, drying, and mechanical processing of active pharmaceutical ingredients
KR102317614B1 (ko) * 2020-05-29 2021-10-27 한국과학기술연구원 금속 컬럼을 제조하는 방법
KR102456996B1 (ko) * 2020-07-21 2022-10-24 한국과학기술원 3d 프린팅을 활용한 뉴럴 프로브와 그의 제조 방법 및 그를 포함하는 의료 디바이스
CN111948312B (zh) * 2020-08-11 2021-04-16 四川大学 一种高效高速分析型逆流色谱仪
CN112345677B (zh) * 2020-11-09 2021-10-22 四川大学 一种双分离柱单侧自解绕高速逆流色谱仪
HUP2300161A1 (hu) * 2023-05-12 2024-11-28 Lilichro Kft Centrifugális megoszlásos kromatográfiás extrakciós cella, ezzel ellátott rotor, alkalmazása centrifugális megoszlásos kromatográfiás berendezésben, és kromatográfiás eljárás
CN116637403B (zh) * 2023-07-25 2023-09-22 河北乐开节能科技股份有限公司 一种用于脱盐脱色的层析分离装置

Citations (1)

* Cited by examiner, † Cited by third party
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CN201143392Y (zh) * 2007-11-01 2008-11-05 北京工商大学 一种适用于小分子和生物大分子分离的逆流色谱分离柱

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US4324661A (en) * 1980-05-09 1982-04-13 The United States Of America As Represented By The Department Of Health, Education And Welfare Apparatus and method for continuous countercurrent extraction and particle separation
JPH0438290Y2 (enExample) * 1985-08-21 1992-09-08
US4894152A (en) 1987-08-13 1990-01-16 Cerex Corporation Fluid control device
US5104531A (en) * 1990-02-26 1992-04-14 The United States Of America As Represented By The Department Of Health And Human Services Cross-axis synchronous flow through coil planet centrifuge for large scale preparative countercurrent chromatography
US5143630A (en) * 1991-05-30 1992-09-01 Membrex, Inc. Rotary disc filtration device
US5993674A (en) * 1998-02-24 1999-11-30 Membrex, Inc. Rotary disc filtration device with means to reduce axial forces
US6296749B1 (en) 1999-04-13 2001-10-02 The Regents Of The University Of California System and method for chromatography and electrophoresis using circular optical scanning
AU2003228367A1 (en) * 2002-04-05 2003-10-27 The Government Of The United States Of America, As Represented By The Secretary, Department Of Healt Method and apparatus for counterconcurrent chromatography
EP1492623B1 (en) * 2002-04-05 2010-07-28 Dynamic Extractions Limited Centrifuge
WO2004085020A2 (en) 2003-03-21 2004-10-07 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Apparatus for countercurrent chromatography
GB0322144D0 (en) 2003-09-23 2003-10-22 Amersham Biosciences Ab Chromatography column distribution system
US7367962B2 (en) * 2004-09-09 2008-05-06 Jms Co., Ltd. Winged medical needle device
WO2006116613A1 (en) * 2005-04-27 2006-11-02 C.R. Bard, Inc. Infusion apparatuses
CN101229452A (zh) * 2007-11-01 2008-07-30 北京工商大学 一种多功能高效逆流色谱仪
US9028693B2 (en) * 2007-12-07 2015-05-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Apparatus for countercurrent chromatography

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201143392Y (zh) * 2007-11-01 2008-11-05 北京工商大学 一种适用于小分子和生物大分子分离的逆流色谱分离柱

Also Published As

Publication number Publication date
US20140091036A1 (en) 2014-04-03
WO2010059715A2 (en) 2010-05-27
US20120037567A1 (en) 2012-02-16
EP2366104A4 (en) 2013-09-11
WO2010059715A3 (en) 2010-08-26
KR20110097863A (ko) 2011-08-31
HK1165205A1 (zh) 2012-09-28
JP2015121555A (ja) 2015-07-02
US8597509B2 (en) 2013-12-03
US9713778B2 (en) 2017-07-25
KR101717302B1 (ko) 2017-03-27
EP2366104B1 (en) 2017-12-27
CN102282464A (zh) 2011-12-14
JP2012509481A (ja) 2012-04-19
JP5997789B2 (ja) 2016-09-28
EP2366104A2 (en) 2011-09-21
JP5695572B2 (ja) 2015-04-08

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