CN102267998A - 新型抗寄生虫吡嗪异喹啉衍生物 - Google Patents
新型抗寄生虫吡嗪异喹啉衍生物 Download PDFInfo
- Publication number
- CN102267998A CN102267998A CN201110154047XA CN201110154047A CN102267998A CN 102267998 A CN102267998 A CN 102267998A CN 201110154047X A CN201110154047X A CN 201110154047XA CN 201110154047 A CN201110154047 A CN 201110154047A CN 102267998 A CN102267998 A CN 102267998A
- Authority
- CN
- China
- Prior art keywords
- compound
- yuan
- saturated
- ring
- schistosomicide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- YEUJXRDLZAGGKE-UHFFFAOYSA-N C(CC1)CC(CNC2)[N+2]1C2C(CCC1)C2N1CCNC2 Chemical compound C(CC1)CC(CNC2)[N+2]1C2C(CCC1)C2N1CCNC2 YEUJXRDLZAGGKE-UHFFFAOYSA-N 0.000 description 1
- FRRXLPBDNIQKHV-UHFFFAOYSA-N O=CCNC(C1)NCCCC1/[O]=C(\NC1)/N(CC2)C1C2/[O]=C1/N(CCC2)C2CNCC1 Chemical compound O=CCNC(C1)NCCCC1/[O]=C(\NC1)/N(CC2)C1C2/[O]=C1/N(CCC2)C2CNCC1 FRRXLPBDNIQKHV-UHFFFAOYSA-N 0.000 description 1
- ILVXOBCQQYKLDS-UHFFFAOYSA-N [O-][n+]1ccccc1 Chemical compound [O-][n+]1ccccc1 ILVXOBCQQYKLDS-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (7)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110154047.XA CN102267998B (zh) | 2011-05-31 | 2011-05-31 | 新型抗寄生虫吡嗪异喹啉衍生物 |
CN201510117197.1A CN104844606B (zh) | 2011-05-31 | 2011-05-31 | 抗寄生虫吡嗪异喹啉衍生物 |
CN201510117838.3A CN104788457B (zh) | 2011-05-31 | 2011-05-31 | 新型抗寄生虫吡嗪异喹啉衍生物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110154047.XA CN102267998B (zh) | 2011-05-31 | 2011-05-31 | 新型抗寄生虫吡嗪异喹啉衍生物 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510117197.1A Division CN104844606B (zh) | 2011-05-31 | 2011-05-31 | 抗寄生虫吡嗪异喹啉衍生物 |
CN201510117838.3A Division CN104788457B (zh) | 2011-05-31 | 2011-05-31 | 新型抗寄生虫吡嗪异喹啉衍生物 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102267998A true CN102267998A (zh) | 2011-12-07 |
CN102267998B CN102267998B (zh) | 2015-05-13 |
Family
ID=45050475
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201110154047.XA Expired - Fee Related CN102267998B (zh) | 2011-05-31 | 2011-05-31 | 新型抗寄生虫吡嗪异喹啉衍生物 |
CN201510117197.1A Expired - Fee Related CN104844606B (zh) | 2011-05-31 | 2011-05-31 | 抗寄生虫吡嗪异喹啉衍生物 |
CN201510117838.3A Expired - Fee Related CN104788457B (zh) | 2011-05-31 | 2011-05-31 | 新型抗寄生虫吡嗪异喹啉衍生物 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510117197.1A Expired - Fee Related CN104844606B (zh) | 2011-05-31 | 2011-05-31 | 抗寄生虫吡嗪异喹啉衍生物 |
CN201510117838.3A Expired - Fee Related CN104788457B (zh) | 2011-05-31 | 2011-05-31 | 新型抗寄生虫吡嗪异喹啉衍生物 |
Country Status (1)
Country | Link |
---|---|
CN (3) | CN102267998B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102321088A (zh) * | 2011-08-03 | 2012-01-18 | 威海秀水药物研发有限公司 | 一种新型抗血吸虫化合物 |
CN113754666A (zh) * | 2021-09-07 | 2021-12-07 | 凯美克(上海)医药科技有限公司 | 一种苯并吡嗪类化合物及其合成方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4661489A (en) * | 1983-07-16 | 1987-04-28 | Beecham Group P.L.C. | Benzazepines, and their use as anthelminthics |
DE3619030A1 (de) * | 1986-06-06 | 1987-12-10 | Bayer Ag | Topisch anwendbare zubereitungen |
CN1683346A (zh) * | 2005-03-01 | 2005-10-19 | 江苏工业学院 | 吡喹酮合成工艺 |
-
2011
- 2011-05-31 CN CN201110154047.XA patent/CN102267998B/zh not_active Expired - Fee Related
- 2011-05-31 CN CN201510117197.1A patent/CN104844606B/zh not_active Expired - Fee Related
- 2011-05-31 CN CN201510117838.3A patent/CN104788457B/zh not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4661489A (en) * | 1983-07-16 | 1987-04-28 | Beecham Group P.L.C. | Benzazepines, and their use as anthelminthics |
DE3619030A1 (de) * | 1986-06-06 | 1987-12-10 | Bayer Ag | Topisch anwendbare zubereitungen |
CN1683346A (zh) * | 2005-03-01 | 2005-10-19 | 江苏工业学院 | 吡喹酮合成工艺 |
Non-Patent Citations (1)
Title |
---|
胡玉琴,等: "血吸虫病化学预防药物4H -吡嗪并〔2, 1-a〕异喹啉衍生物的合成", 《中国药物化学杂志》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102321088A (zh) * | 2011-08-03 | 2012-01-18 | 威海秀水药物研发有限公司 | 一种新型抗血吸虫化合物 |
CN113754666A (zh) * | 2021-09-07 | 2021-12-07 | 凯美克(上海)医药科技有限公司 | 一种苯并吡嗪类化合物及其合成方法 |
Also Published As
Publication number | Publication date |
---|---|
CN104788457B (zh) | 2017-08-25 |
CN104844606A (zh) | 2015-08-19 |
CN104844606B (zh) | 2017-03-01 |
CN104788457A (zh) | 2015-07-22 |
CN102267998B (zh) | 2015-05-13 |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: SHANDONG UNIVERSITY (WEIHAI) Free format text: FORMER OWNER: SUN DEQUN Effective date: 20150710 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20150710 Address after: 264209 Weihai Cultural Road West, Shandong, No. 180 Patentee after: Shandong University, Weihai Address before: 264209 innovation building, hi tech Zone, Shandong, Weihai 507 Patentee before: Sun Dequn |
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CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150513 Termination date: 20170531 |