CN102258605A - Medicine composition for treating gout and preparation method thereof - Google Patents
Medicine composition for treating gout and preparation method thereof Download PDFInfo
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- CN102258605A CN102258605A CN2010101844146A CN201010184414A CN102258605A CN 102258605 A CN102258605 A CN 102258605A CN 2010101844146 A CN2010101844146 A CN 2010101844146A CN 201010184414 A CN201010184414 A CN 201010184414A CN 102258605 A CN102258605 A CN 102258605A
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Abstract
The invention relates to a medicine composition for treating the gout and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. The medicine composition consists of medicinal materials such as cassia twig, red ginseng and the like, and has good effect.
Description
Technical field
The present invention is a kind of pharmaceutical composition and method for making for the treatment of gout, belongs to the technical field of medicine.
Technical background
Gout is the common chronic disease of modern, is the disease of one group of heritability or acquired uric acid metabolism imbalance.The cause of disease of gout is that uric acid metabolism is unusual, causes blood uric acid too high.So-called uric acid is the catabolic end product of purine compound in the human body, and uricopoiesis increases or the kidney releasing uric acid reduces, and blood uric acid all can increase.Uricopoiesis increases former because: 1. the purine biosynthesis increases.2. the nucleic acid conversion is quickened in the body.3. take in high purine or high purine precursor food.Gout when outbreak, strange painful incomparable, agonizing, though the medicine of western medical treatment gout is a lot, there are shortcomings such as easily recurrence, side effect be many.
In view of such circumstances, providing a kind of determined curative effect, toxic and side effects pharmaceutical composition little, taking convenience is the thing of being badly in need of solution.
Summary of the invention
Technical problem to be solved by this invention provides a kind of pharmaceutical composition and method for making for the treatment of gout; The present invention is directed to prior art, little, the taking convenience of product determined curative effect, toxic and side effects that provides.
Technical scheme of the present invention is to constitute like this: it is made up of following active drug raw material: Ramulus Cinnamomi 5-100g, Radix Ginseng Rubra 5-100g, Radix Glycyrrhizae (processed with honey) 5-100g, Radix Paeoniae Alba 5-100g, Pericarpium Citri Reticulatae 5-100g, Radix Aconiti Lateralis Preparata 5-100g.Be preferably: Ramulus Cinnamomi 5-50g, Radix Ginseng Rubra 5-50g, Radix Glycyrrhizae (processed with honey) 5-50g, Radix Paeoniae Alba 5-50g, Pericarpium Citri Reticulatae 5-50g, Radix Aconiti Lateralis Preparata 5-50g.The method for making of described pharmaceutical composition: the raw material of getting it filled, pulverize or extract, make multiple peroral dosage form then respectively, comprising: tablet, dispersible tablet, capsule, soft capsule, granule, pill, powder, drop pill, gel, oral liquid.
Pharmacodynamic experiment utilization uric acid sodium causes the ankle swelling in rat method, and hypoxanthine causes mice gout method and observes its gout effect; Mice caused by dimethylbenzene xylene auricle edema method, angle justice dish glue causes the rat paw edema method and the carboxymethyl cellulose pouch method is observed its antiinflammatory action.The result shows that this product has tangible reduction gout mice serum uric acid level and antiinflammatory action.And have and increase the trend that gout mouse retention uric acid is discharged.
Concrete embodiment
Embodiment 1: Ramulus Cinnamomi 20g, Radix Ginseng Rubra 20g, Radix Glycyrrhizae (processed with honey) 20g, Radix Paeoniae Alba 20g, Pericarpium Citri Reticulatae 20g, Radix Aconiti Lateralis Preparata 20g
Above flavour of a drug decoct with water 3 times, and each 2 hours, each amount of water was 8 times of medical material, collecting decoction, filter, filtrate concentrates, and adding ethanol is 50% to containing the alcohol amount, leaves standstill 24 hours, filter, filtrate recycling ethanol concentrates drying to there not being the alcohol flavor, get dry extract, add starch, grinding and sieving, granulate with dehydrated alcohol, granulate promptly gets granule, oral, a 5g, 3 times on the one.
Embodiment 2: Ramulus Cinnamomi 5g, Radix Ginseng Rubra 5g, Radix Glycyrrhizae (processed with honey) 5g, Radix Paeoniae Alba 5g, Pericarpium Citri Reticulatae 5g, Radix Aconiti Lateralis Preparata 5g
Above flavour of a drug decoct with water 4 times, and each 3 hours, each amount of water was 8 times of medical material, collecting decoction filters, and filtrate concentrates, adding ethanol is 50% to containing the alcohol amount, leaves standstill 36 hours, filters, filtrate recycling ethanol concentrates drying under reduced pressure to there not being the alcohol flavor, get dry extract, add starch, grinding and sieving, tabletting promptly gets tablet.
Embodiment 3: Ramulus Cinnamomi 50g, Radix Ginseng Rubra 50g, Radix Glycyrrhizae (processed with honey) 50g, Radix Paeoniae Alba 50g, Pericarpium Citri Reticulatae 50g, Radix Aconiti Lateralis Preparata 50g
Above flavour of a drug decoct with water 2 times, and each 4 hours, each amount of water was 8 times of medical material, collecting decoction, filter, filtrate concentrates, and adding ethanol is 50% to containing the alcohol amount, leaves standstill 12 hours, filters, filtrate recycling ethanol concentrates to there not being the alcohol flavor, and drying under reduced pressure is moulded the method for making pill, promptly gets soft capsule.
Embodiment 4: Ramulus Cinnamomi 100g, Radix Ginseng Rubra 100g, Radix Glycyrrhizae (processed with honey) 100g, Radix Paeoniae Alba 100g, Pericarpium Citri Reticulatae 100g, Radix Aconiti Lateralis Preparata 100g
Above flavour of a drug decoct with water three times, add 4 times of water gagings at every turn and decoct 2 hours, and collecting decoction filters, and concentrates, and promptly gets oral liquid.
Embodiment 5: Ramulus Cinnamomi 6g, Radix Ginseng Rubra 8g, Radix Glycyrrhizae (processed with honey) 10g, Radix Paeoniae Alba 7g, Pericarpium Citri Reticulatae 5g, Radix Aconiti Lateralis Preparata 6g
Above flavour of a drug decoct with water three times, add 4 times of water gagings at every turn and decoct 1.5 hours, and collecting decoction filters, and concentrates, and promptly gets oral liquid.
Embodiment 6: Ramulus Cinnamomi 90g, Radix Ginseng Rubra 100g, Radix Glycyrrhizae (processed with honey) 80g, Radix Paeoniae Alba 70g, Pericarpium Citri Reticulatae 50g, Radix Aconiti Lateralis Preparata 5g
Above flavour of a drug decoct with water three times, add 6 times of water gagings at every turn and decoct 3 hours, and collecting decoction filters, and concentrates, and general method for making pill promptly gets pill.
Embodiment 7: Ramulus Cinnamomi 5g, Radix Ginseng Rubra 50g, Radix Glycyrrhizae (processed with honey) 40g, Radix Paeoniae Alba 30g, Pericarpium Citri Reticulatae 40g, Radix Aconiti Lateralis Preparata 50g
Above flavour of a drug decoct with water three times, add 7 times of water gagings at every turn and decoct 2.5 hours, and collecting decoction filters, and concentrates, and extrudes-the circule method pill, promptly gets pellet.
Embodiment 8: Ramulus Cinnamomi 40g, Radix Ginseng Rubra 40g, Radix Glycyrrhizae (processed with honey) 50g, Radix Paeoniae Alba 30g, Pericarpium Citri Reticulatae 48g, Radix Aconiti Lateralis Preparata 20g
Above flavour of a drug decoct with water three times, add 5 times of water gagings at every turn and decoct 2.5 hours, and collecting decoction filters, and concentrate, and drying is pulverized, and promptly gets powder.
Embodiment 9: Ramulus Cinnamomi 6g, Radix Ginseng Rubra 10g, Radix Glycyrrhizae (processed with honey) 50g, Radix Paeoniae Alba 40g, Pericarpium Citri Reticulatae 20g, Radix Aconiti Lateralis Preparata 10g
Above flavour of a drug decoct with water three times, add 3 times of water gagings at every turn and decoct 3 hours, and collecting decoction filters, and concentrate, and drying is pulverized, and promptly gets powder.
Claims (3)
1. pharmaceutical composition for the treatment of gout, it is characterized in that: it is made up of following active drug raw material: Ramulus Cinnamomi 5-100g, Radix Ginseng Rubra 5-100g, Radix Glycyrrhizae (processed with honey) 5-100g, Radix Paeoniae Alba 5-100g, Pericarpium Citri Reticulatae 5-100g, Radix Aconiti Lateralis Preparata 5-100g.
2. according to the pharmaceutical composition of the described treatment gout of claim 1, it is characterized in that: it is made up of following active drug raw material: Ramulus Cinnamomi 5-50g, Radix Ginseng Rubra 5-50g, Radix Glycyrrhizae (processed with honey) 5-50g, Radix Paeoniae Alba 5-50g, Pericarpium Citri Reticulatae 5-50g, Radix Aconiti Lateralis Preparata 5-50g.
3. according to the method for making of the pharmaceutical composition of any described treatment gout of claim 1-2, it is characterized in that: the raw material of getting it filled, pulverize or extract, make multiple peroral dosage form then respectively, comprising: tablet, dispersible tablet, capsule, soft capsule, granule, pill, powder, drop pill, gel, oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101844146A CN102258605A (en) | 2010-05-27 | 2010-05-27 | Medicine composition for treating gout and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101844146A CN102258605A (en) | 2010-05-27 | 2010-05-27 | Medicine composition for treating gout and preparation method thereof |
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| CN102258605A true CN102258605A (en) | 2011-11-30 |
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| CN2010101844146A Pending CN102258605A (en) | 2010-05-27 | 2010-05-27 | Medicine composition for treating gout and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895337A (en) * | 2012-10-22 | 2013-01-30 | 郭玲玲 | Medicine for treating gout |
| CN104587177A (en) * | 2015-01-08 | 2015-05-06 | 海南蛛王药业有限公司 | Li medicine preparation for treating gout and preparation method thereof |
| CN107260998A (en) * | 2017-06-26 | 2017-10-20 | 陈国忠 | It is a kind of to be used to treat Chinese medicine preparation of gout and preparation method thereof |
-
2010
- 2010-05-27 CN CN2010101844146A patent/CN102258605A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895337A (en) * | 2012-10-22 | 2013-01-30 | 郭玲玲 | Medicine for treating gout |
| CN104587177A (en) * | 2015-01-08 | 2015-05-06 | 海南蛛王药业有限公司 | Li medicine preparation for treating gout and preparation method thereof |
| CN104587177B (en) * | 2015-01-08 | 2017-09-15 | 海南蛛王药业有限公司 | It is a kind of to treat multitude's medicine preparation of gout and preparation method thereof |
| CN107260998A (en) * | 2017-06-26 | 2017-10-20 | 陈国忠 | It is a kind of to be used to treat Chinese medicine preparation of gout and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| DD01 | Delivery of document by public notice |
Addressee: Zhang Jinrong Document name: Notification of Publication of the Application for Invention |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20111130 |