CN104587177B - It is a kind of to treat multitude's medicine preparation of gout and preparation method thereof - Google Patents
It is a kind of to treat multitude's medicine preparation of gout and preparation method thereof Download PDFInfo
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- CN104587177B CN104587177B CN201510008382.7A CN201510008382A CN104587177B CN 104587177 B CN104587177 B CN 104587177B CN 201510008382 A CN201510008382 A CN 201510008382A CN 104587177 B CN104587177 B CN 104587177B
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Abstract
The present invention relates to field of traditional Chinese, disclose and a kind of treat multitude's medicine preparation of gout and preparation method thereof.The freeze-dried powder that the spider of Hainan characteristic is made is used in prescription for raw material, inside can dredging the channel, conditioning viscera function, promotion metabolism in vivo, quickening interior metabolism product discharge, the basic reason that elimination gout is produced by prescription compatibility；Notable is acted on to symptoms such as red caused by gout, swollen, hot, pains outside, the root for causing gout in vivo can be removed, mitigates the symptom of gout, reaches the purpose for the treatment of a disease by looking into both its root cause and symptoms.
Description
Technical field
The present invention relates to field of traditional Chinese, particularly relate to a kind of treat multitude's medicine preparation of gout and preparation method thereof.
Background technology
Gout is a kind of " rich man's disease " caused by internal purine metabolism dysfunction or hyperuricemia.Once suffer from pain
Wind, the lighter's key swelling is ached, and heavy then limbs are deformed, and forms joint deformity or kidney stone, causes kidney failure and threat to life.Bitterly
The treatment of wind is typically chosen the chemical agents such as oral probenecid, colchicin.And for a long time take orally chemicals, patient easily by
Stomach and liver kidney injury.According to clinical investigation, patient with gout more than 90% is with different degrees of Central obesity, hypertension, height
Blood fat, diabetes and cardiovascular and cerebrovascular disease；More than 50% patient with gout occurs dysarthrasis, severe patient have disable can
Energy；More than 40% patient with gout can trigger the serious renal lesions such as uremia, life-threatening.
Chinese medicine derives from natural plant, animal or mineral, and toxic side effect is small, and conditioning can be played to whole body and is made
With reaching the purpose treated both principal and secondary aspect of disease.Therefore, increasing people by application in TCM in the treatment of gout.Such as Chinese invention patent
CN102198202A discloses a kind of Chinese medicine for treating gout, can occasionally make the vital organs of the human body in order, fundamentally treats gout, cost
Low, toxic side effect is small, and therapeutic effect is preferable.
The content of the invention
The present invention proposes a kind of multitude's medicine preparation for treating gout, and with strong points, effect is notable, toxic side effect is small.
The technical proposal of the invention is realized in this way：
A kind of multitude's medicine preparation for treating gout, includes the component of following mass fraction：1-5 parts of spider freeze-drying powder, red ginseng 5-
15 parts, 5-15 parts of saline cistanche, 1-10 parts of Radix Angelicae Sinensis, 5-15 parts of the fruit of Chinese magnoliavine, 5-15 parts of tuber of dwarf lilyturf 5-15 part, pilose antler, 5-15 parts of sargentodoxa cuneata,
1-10 parts of caulis piperis futokadsurae, loose 5-15 parts of muscle grass, 5-15 parts of Glochidion puberum 10-30 Fen , pig label grass.
Further, multitude's medicine preparation of the treatment gout, includes the component of following mass fraction：1-3 parts of spider freeze-drying powder,
10-14 parts of red ginseng, 10-14 parts of saline cistanche, 4-8 parts of Radix Angelicae Sinensis, 10-14 parts of the fruit of Chinese magnoliavine, tuber of dwarf lilyturf 10-14 part, 10-14 parts of pilose antler, greatly
10-14 parts of blood rattan, 1-5 parts of caulis piperis futokadsurae, loose 10-14 parts of muscle grass, 8-12 parts of Glochidion puberum 20-30 Fen , pig label grass.
Further, the spider freeze-drying powder is Selenocosmiahuwena freeze-dried powder, Jingzhao chilobrachys spider freeze-dried powder or the mixing of the two
Thing.
Preferably, the mass fraction of each component is in multitude's medicine preparation of the treatment gout, prescription：Spider freeze-drying powder 2
Part, 12 parts of red ginseng, 12 parts of saline cistanche, 6 parts of Radix Angelicae Sinensis, 12 parts of the fruit of Chinese magnoliavine, 12 parts of the tuber of dwarf lilyturf, 12 parts of pilose antler, 12 parts of sargentodoxa cuneata, caulis piperis futokadsurae
3 parts, loose 12 parts of muscle grass, 10 parts of the Fen , pig label of Glochidion puberum 30 grass.
A kind of preparation method for the multitude's medicine preparation for treating gout, comprises the following steps：
(1) red ginseng, saline cistanche, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, the tuber of dwarf lilyturf, pilose antler, sargentodoxa cuneata, caulis piperis futokadsurae, loose muscle are weighed by formula rate
Grass, Glochidion puberum, pig label grass, are remembered with medicinal material gross mass, the edible alcohol of 5-8 times of addition medicinal material gross mass, ultrasonic extraction 2 times,
0.5-1.5 hours every time, filter to obtain extract solution；
(2) merge extract solution twice, add the spider freeze-drying powder of formula ratio, be filtered to remove insoluble matter, sterilize, produce this
The described preparation of invention.
Further, in the step (1), edible alcohol by volume concentration is 70-80%.
Beneficial effects of the present invention：
Multitude's medicine preparation for the treatment of gout of the present invention, use in prescription the freeze-dried powder that the spider of Hainan characteristic is made for
Raw material, by prescription compatibility, with dispelling wind and removing obstruction in the meridians, clearing heat and detoxicating, damp-clearing pain-relieving, inside can dredging the channel, conditioning viscera function,
Promote metabolism in vivo, accelerate interior metabolism product discharge, eliminate the basic reason that gout is produced；Outside to caused by gout
The symptom effect such as red, swollen, hot, pain is notable, can remove the root for causing gout in vivo, mitigates the symptom of gout, reaches sample
With the purpose controlled.
Spider has effects that drastically removing blood stasis and resolving static blood, removing toxicity for detumescence, helps to eliminate gout focus, effect of swelling and pain relieving can have
Red, swollen, pain symptom caused by gout breaking-out is mitigated or eliminated in effect.
Caulis piperis futokadsurae wind-damp dispelling, degrading the channel, it is evident in efficacy for wind-cold-dampness arthralgia, articular instability, lumbocrural pain, muscle arteries and veins contraction；
Glochidion puberum is clearing heat and detoxicating, the promoting flow of qi and blood circulation；Sargentodoxa cuneata is promoting blood circulation and removing obstruction in channels；Loose muscle grass is clearing heat and detoxicating, promoting diuresis for stranguria.Four are commonly applied to
, can be with clearing heat for detumescence, tranquilizing and allaying excitement, to red and swollen evident in efficacy caused by gout, while can also alleviate due to gout in prescription
The symptom such as pain, heating caused by breaking-out..
Pig label grass has remove rheumatism, strong muscles and bones, clearing heat and detoxicating effect, on the one hand can be with calm nerves, solution of bringing down a fever
Poison, alleviates gout breaking-out symptom, and on the other hand its strengthening tendons, strong bone effect, can build up health, and improve metabolism in vivo, promote body
Interior physiological function recovers normal, is inherently eliminated the breaking-out of gout.
In prescription, the effect that saline cistanche has kidney-replenishing, benefiting essence-blood, relaxed bowel, red ginseng is consolidated with reinforcing vital energy, answering arteries and veins
The effect of de-, nourishing qi to stop, Chinese angelica blood supplementing promoting blood circulation, moisturize laxation, pilose antler mend marrow, strengthening the bones and muscles, adjust punching to appoint, along with receipts
Hold back astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, the fruit of Chinese magnoliavine of kidney calming effect, and Yin-nourishing and body fluid promoting the tuber of dwarf lilyturf, one side nourishment for vitality moistens and fosters the spirit of nobility
Blood, builds up health；On the other hand, the function of other medicinal materials, reaches in promoting the circulation of qi, promoting circulation of blood, conditioning viscera function, auxiliary enhancing prescription
The effect of Synergistic.
Above medicinal material is used in conjunction with, and the pathogeny of ventilation breaking-out is removed inside, internal organs function is taken good care of, builds up health；Disappear outside
Except the symptom of ventilation breaking-out, the effect for alleviating, treating gout from inside to outside is reached, so as to reach the purpose treated both principal and secondary aspect of disease.
Embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the present invention is clearly and completely described, it is clear that
Described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based on the implementation in the present invention
Example, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made is belonged to
The scope of protection of the invention.
Embodiment 1
A kind of multitude's medicine preparation for treating gout, includes the component Selenocosmiahuwena freeze-dried powder 1g of following mass fraction, red ginseng
5g, saline cistanche 5g, Radix Angelicae Sinensis 1g, fruit of Chinese magnoliavine 5g, tuber of dwarf lilyturf 5g, pilose antler 5g, sargentodoxa cuneata 5g, caulis piperis futokadsurae 1g, loose muscle grass 5g, Glochidion puberum
10g , pig label grass 5g.
A kind of preparation method for the multitude's medicine preparation for treating gout, comprises the following steps：
(1) red ginseng, saline cistanche, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, pilose antler, the tuber of dwarf lilyturf, sargentodoxa cuneata, loose muscle grass, sea wind are weighed by formula rate
Rattan, Glochidion puberum, pig label grass, are remembered with medicinal material gross mass, the edible alcohol of 5 times of addition medicinal material gross mass, ultrasonic extraction 2 times, often
It is secondary 0.5-1.5 hours, filter to obtain extract solution；Edible alcohol by volume concentration is 70%；
(2) merge extract solution twice, add the Selenocosmiahuwena freeze-dried powder of formula ratio, be filtered to remove insoluble matter, sterilize,
Produce preparation of the present invention.
Embodiment 2
A kind of multitude's medicine preparation for treating gout, includes the component of following mass fraction：Selenocosmiahuwena freeze-dried powder 5g, red ginseng
15g, saline cistanche 15g, Radix Angelicae Sinensis 10g, fruit of Chinese magnoliavine 15g, tuber of dwarf lilyturf 15g, pilose antler 15g, sargentodoxa cuneata 15g, caulis piperis futokadsurae 10g, loose muscle grass
15g, Glochidion puberum 30g , pig label grass 15g.
A kind of preparation method for the multitude's medicine preparation for treating gout, it is characterised in that comprise the following steps：
(1) red ginseng, saline cistanche, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, pilose antler, the tuber of dwarf lilyturf, sargentodoxa cuneata, loose muscle grass, sea wind are weighed by formula rate
Rattan, Glochidion puberum, pig label grass, remembered with medicinal material gross mass, the edible alcohol of 8 times of addition medicinal material gross mass, ultrasonic extraction 2 times, often
It is secondary 0.5-1.5 hours, filter to obtain extract solution；Edible alcohol by volume concentration is 80%；
(2) merge extract solution twice, add the Selenocosmiahuwena freeze-dried powder of formula ratio, be filtered to remove insoluble matter, sterilize,
Produce preparation of the present invention.
Embodiment 3
A kind of multitude's medicine preparation for treating gout, includes the component of following mass fraction：Jingzhao chilobrachys spider freeze-dried powder 1g, red ginseng
10g, saline cistanche 10g, Radix Angelicae Sinensis 4g, fruit of Chinese magnoliavine 10g, tuber of dwarf lilyturf 10g, pilose antler 10g, sargentodoxa cuneata 10g, caulis piperis futokadsurae 1g, loose muscle grass 10g,
Glochidion puberum 20g , pig label grass 8g.
A kind of preparation method for the multitude's medicine preparation for treating gout, comprises the following steps：
(1) red ginseng, saline cistanche, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, pilose antler, the tuber of dwarf lilyturf, sargentodoxa cuneata, loose muscle grass, sea wind are weighed by formula rate
Rattan, Glochidion puberum, pig label grass, are remembered with medicinal material gross mass, and the edible alcohol ultrasonic extraction of 5 times of addition medicinal material gross mass 2 times is edible
It is 70% with alcohol by volume concentration, 0.5 hour every time, filters to obtain extract solution；
(2) merge extract solution twice, add the Jingzhao chilobrachys spider freeze-dried powder of formula ratio, be filtered to remove insoluble matter, sterilize,
Produce preparation of the present invention.
Embodiment 4
A kind of multitude's medicine preparation for treating gout, includes the component of following mass fraction：Spider freeze-drying powder 2g, red ginseng 12g, meat
Desert cistanche 12g, Radix Angelicae Sinensis 6g, fruit of Chinese magnoliavine 12g, tuber of dwarf lilyturf 12g, pilose antler 12g, sargentodoxa cuneata 12g, caulis piperis futokadsurae 3g, loose muscle grass 12g, Glochidion puberum
25g , pig label grass 10g.
A kind of preparation method for the multitude's medicine preparation for treating gout, comprises the following steps：
(1) red ginseng, saline cistanche, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, pilose antler, the tuber of dwarf lilyturf, sargentodoxa cuneata, loose muscle grass, sea wind are weighed by formula rate
Rattan, Glochidion puberum, pig label grass, are remembered with medicinal material gross mass, the edible alcohol of 6 times of addition medicinal material gross mass, ultrasonic extraction 2 times, often
Secondary 1.0 hours, the volumetric concentration of edible alcohol was 75%, filters to obtain extract solution；
(2) merge extract solution twice, add the spider freeze-drying powder of formula ratio, be filtered to remove insoluble matter, sterilize, produce this
The described preparation of invention.
Embodiment 5
A kind of multitude's medicine preparation for treating gout, includes the component of following mass fraction：Selenocosmiahuwena freeze-dried powder and respecting is encouraged
Tassel hair spider lyophilized powder mixture 3g, red ginseng 14g, saline cistanche 14g, Radix Angelicae Sinensis 8g, fruit of Chinese magnoliavine 14g, tuber of dwarf lilyturf 14g, pilose antler 14g, big blood
Rattan 14g, caulis piperis futokadsurae 5g, loose muscle grass 14g, Glochidion puberum 30g , pig label grass 12g.
A kind of preparation method for the multitude's medicine preparation for treating gout, comprises the following steps：
(1) red ginseng, saline cistanche, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, pilose antler, the tuber of dwarf lilyturf, sargentodoxa cuneata, loose muscle grass, sea wind are weighed by formula rate
Rattan, Glochidion puberum, pig label grass, are remembered with medicinal material gross mass, add the edible alcohol of 5-8 times of medicinal material gross mass, edible alcohol body
Product concentration is 80%, and ultrasonic extraction 2 times is each 0.5-1.5 hours, filters to obtain extract solution；
(2) merge extract solution twice, add the spider freeze-drying powder of formula ratio, be filtered to remove insoluble matter, sterilize, get Ben Fa
Bright described preparation.
Obtained preparation in above example, can be made vina or tincture etc. according to the demand and medication custom of patient
Formulation.
The application effect of multitude's medicine preparation for the treatment of gout of the present invention is investigated
The patient with gout 80 made a definite diagnosis is selected, 4 groups are allocated as at random, is treated respectively according to following scheme：
Scheme 1：Give and utilize medicament made from the preparation of the gained of the embodiment of the present invention 1；
Scheme 2：Give and utilize medicament made from the preparation of the gained of the embodiment of the present invention 2；
Scheme 3：Give and utilize medicament made from the preparation of the gained of the embodiment of the present invention 3；
Scheme 4：Give conventional chemical drug therapy.
Therapeutic effect is evaluated by following standard：
It is effective --- the symptom such as arthralgia, redness is disappeared, and joint motion is unrestricted, and joint motion is reduced；
Effectively --- the symptom such as arthralgia, redness is substantially eliminated, and joint motion is slightly limited；
It is invalid --- the symptom such as arthralgia, redness and joint motion are not improved.
Treated respectively after 3 months according to above therapeutic scheme, record the curative effect of each therapeutic scheme, be shown in Table 1.
The preparation for treating effect assessment of the treatment gout of the present invention of table 1
As shown in Table 1, it is total effectively more than 90% by using the gout preparations for the treatment of of the present invention, its curative effect
It is suitable with conventional chemotherapy.In therapeutic process, the medicine being made using preparation obtained by 3 embodiments of the present invention is taken
There are 52 patient's reflection state of mind to improve significantly in agent, 60 people, while digestive system function improves significantly, the colour of skin
Dark black, dry symptom have clear improvement, and chest gastral cavity ruffian symptom mitigation, sleep quality is significantly increased.Illustrate of the present invention
Multitude's medicine preparation of gout is treated, there is opsonic action to internal organs function, progress metabolic in human body can be promoted, be conducive to
The root for causing gout in vivo is removed, with the curative effect treated both principal and secondary aspect of disease.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
God is with principle, and any modification, equivalent substitution and improvements made etc. should be included in the scope of the protection.
Claims (5)
1. a kind of multitude's medicine preparation for treating gout, it is characterised in that include the component of following mass fraction：Spider freeze-drying powder 1-5
Part, 5-15 parts of red ginseng, 5-15 parts of saline cistanche, 1-10 parts of Radix Angelicae Sinensis, 5-15 parts of the fruit of Chinese magnoliavine, tuber of dwarf lilyturf 5-15 part, 5-15 parts of pilose antler, big blood
5-15 parts of rattan, 1-10 parts of caulis piperis futokadsurae, loose 5-15 parts of muscle grass, 5-15 parts of Glochidion puberum 10-30 Fen , pig label grass.
2. a kind of multitude's medicine preparation for treating gout according to claim 1, it is characterised in that including following mass fraction
Component：1-3 parts of spider freeze-drying powder, 10-14 parts of red ginseng, 10-14 parts of saline cistanche, 4-8 parts of Radix Angelicae Sinensis, 10-14 parts of the fruit of Chinese magnoliavine, the tuber of dwarf lilyturf
10-14 parts, 10-14 parts of pilose antler, 10-14 parts of sargentodoxa cuneata, 1-5 parts of caulis piperis futokadsurae, loose 10-14 parts of muscle grass, Glochidion puberum 20-30 Fen , pig
Sign 8-12 parts of grass.
3. a kind of multitude's medicine preparation for treating gout according to any one of claim 1 or 2, it is characterised in that：The spider
Freeze-dried powder is Selenocosmiahuwena freeze-dried powder, Jingzhao chilobrachys spider freeze-dried powder or the mixture of the two.
4. the preparation method of multitude's medicine preparation of the treatment gout according to any one of claims 1 to 3, it is characterised in that bag
Include following steps：
(1) by formula rate weigh red ginseng, saline cistanche, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, the tuber of dwarf lilyturf, pilose antler, sargentodoxa cuneata, caulis piperis futokadsurae, loose muscle grass,
Caulis piperis futokadsurae, Glochidion puberum, pig label grass, are remembered with medicinal material gross mass, add the edible alcohol of 5-8 times of medicinal material gross mass, ultrasonic extraction 2
It is secondary, it is each 0.5-1.5 hours, filter to obtain extract solution；
(2) merge extract solution twice, add the spider freeze-drying powder of formula ratio, be filtered to remove insoluble matter, sterilize, produce the present invention
Described preparation.
5. a kind of preparation method of multitude's medicine preparation for treating gout according to claim 4, it is characterised in that：The step
(1) in, edible alcohol by volume concentration is 70-80%.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510008382.7A CN104587177B (en) | 2015-01-08 | 2015-01-08 | It is a kind of to treat multitude's medicine preparation of gout and preparation method thereof |
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| CN201510008382.7A CN104587177B (en) | 2015-01-08 | 2015-01-08 | It is a kind of to treat multitude's medicine preparation of gout and preparation method thereof |
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| CN104587177B true CN104587177B (en) | 2017-09-15 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258605A (en) * | 2010-05-27 | 2011-11-30 | 张金荣 | Medicine composition for treating gout and preparation method thereof |
| CN103405682A (en) * | 2013-08-22 | 2013-11-27 | 刘效义 | Traditional Chinese medicine for treating gout and preparation method thereof |
-
2015
- 2015-01-08 CN CN201510008382.7A patent/CN104587177B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258605A (en) * | 2010-05-27 | 2011-11-30 | 张金荣 | Medicine composition for treating gout and preparation method thereof |
| CN103405682A (en) * | 2013-08-22 | 2013-11-27 | 刘效义 | Traditional Chinese medicine for treating gout and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 中医药治疗痛风的近况及展望;曹世霞;《赤峰学院学报（自然科学版）》;20121031;第28卷(第10期);112-114 * |
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Denomination of invention: Li medicine preparation for treating gout and preparation method thereof Effective date of registration: 20190215 Granted publication date: 20170915 Pledgee: Bank of Hainan Limited by Share Ltd Pledgor: HAINAN ZHUWANG PHARMACEUTICAL CO., LTD. Registration number: 2019460000002 |
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Effective date of registration: 20210209 Address after: 570000 room 11a, Xinda commercial building, No.5, Huafu Road, Longhua District, Haikou City, Hainan Province Patentee after: Hainan ZIWANG liyitang Co.,Ltd. Address before: 570100 room 11a, Xinda commercial building, No.5, Huafu Road, Longhua District, Haikou City, Hainan Province Patentee before: HAINAN ZHUWANG PHARMACEUTICAL Co.,Ltd. |