CN102245239B - 吸入装置和分配药物的方法 - Google Patents

吸入装置和分配药物的方法 Download PDF

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Publication number
CN102245239B
CN102245239B CN2009801491192A CN200980149119A CN102245239B CN 102245239 B CN102245239 B CN 102245239B CN 2009801491192 A CN2009801491192 A CN 2009801491192A CN 200980149119 A CN200980149119 A CN 200980149119A CN 102245239 B CN102245239 B CN 102245239B
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CN
China
Prior art keywords
actuator
inhaler
chamber
ethyl
paillon foil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2009801491192A
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English (en)
Chinese (zh)
Other versions
CN102245239A (zh
Inventor
威廉.贝克维尔
约翰.布赖恩特
帕特里克.坎贝尔
查尔斯.库克
克里斯多夫.格罗姆布里奇
尼古拉斯.哈里森
詹姆斯.D.约翰
奥雷斯特.拉斯托
尼古拉斯.斯马特
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AstraZeneca AB
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AstraZeneca AB
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Publication of CN102245239A publication Critical patent/CN102245239A/zh
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Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043—Non-destructive separation of the package, e.g. peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0096—Hindering inhalation before activation of the dispenser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, spherical or like small articles, e.g. tablets or pills
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/06—Containers or packages with special means for dispensing contents for dispensing powdered or granular material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN2009801491192A 2008-10-08 2009-10-07 吸入装置和分配药物的方法 Expired - Fee Related CN102245239B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10360608P 2008-10-08 2008-10-08
US61/103,606 2008-10-08
PCT/SE2009/051110 WO2010042033A1 (en) 2008-10-08 2009-10-07 Inhalation device and method of dispensing medicament

Publications (2)

Publication Number Publication Date
CN102245239A CN102245239A (zh) 2011-11-16
CN102245239B true CN102245239B (zh) 2013-08-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801491192A Expired - Fee Related CN102245239B (zh) 2008-10-08 2009-10-07 吸入装置和分配药物的方法

Country Status (17)

Country Link
US (1) US9095670B2 (enExample)
EP (1) EP2334358B1 (enExample)
JP (1) JP5518082B2 (enExample)
KR (1) KR20110074766A (enExample)
CN (1) CN102245239B (enExample)
AU (1) AU2009302956B8 (enExample)
BR (1) BRPI0920658A2 (enExample)
CA (1) CA2738822A1 (enExample)
CL (1) CL2011000789A1 (enExample)
EA (1) EA019293B1 (enExample)
ES (1) ES2579902T3 (enExample)
IL (1) IL212074A0 (enExample)
MX (1) MX2011003759A (enExample)
NZ (1) NZ591956A (enExample)
UA (1) UA101056C2 (enExample)
WO (1) WO2010042033A1 (enExample)
ZA (1) ZA201103334B (enExample)

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DE102005057685A1 (de) * 2005-12-01 2007-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung
US9889087B2 (en) * 2014-06-10 2018-02-13 The Board Of Trustees Of The Leland Stanford Junior University Intranasal delivery of β2-adrenergic receptor agonists for improving cognition in humans with down syndrome and compositions therefor
ES2908479T3 (es) 2015-08-26 2022-04-29 Achillion Pharmaceuticals Inc Compuestos para el tratamiento de trastornos inmunitarios e inflamatorios
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
EP3939591A1 (en) 2016-06-27 2022-01-19 Achillion Pharmaceuticals, Inc. Quinazoline and indole compounds to treat medical disorders
GB2553534A (en) * 2016-09-07 2018-03-14 3M Innovative Properties Co Trigger mechanism for an inhaler
GB201615186D0 (en) * 2016-09-07 2016-10-19 3M Innovative Properties Co Energy storage mechanism for an inhaler
CN110603252A (zh) 2017-03-01 2019-12-20 艾其林医药公司 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
BR112019019107A2 (pt) 2017-03-15 2020-04-22 Csp Technologies Inc inalador e métodos de uso e produção do mesmo
CN110271772B (zh) * 2018-03-13 2023-09-15 李和伟 一种给药器
US20230022157A1 (en) 2018-08-20 2023-01-26 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
JP7504088B2 (ja) 2018-10-16 2024-06-21 ジョージア ステイト ユニバーシティー リサーチ ファウンデーション インコーポレイテッド 医学的障害の治療のための一酸化炭素プロドラッグ
US11253035B2 (en) 2019-01-22 2022-02-22 Coopervision International Holding Company, Lp Blister package for contact lens
US11267643B2 (en) 2019-01-22 2022-03-08 Coopervision International Limited Contact lens dispenser
US11136176B2 (en) 2019-01-22 2021-10-05 Coopervision International Limited Contact lens blister package with lens cradle
US11419397B2 (en) 2019-01-22 2022-08-23 Coopervision International Limited Push-up contact lens blister package
US11229266B2 (en) 2019-01-22 2022-01-25 Coopervision International Limited Tessellating blister packages for contact lenses
US12053069B2 (en) 2019-01-22 2024-08-06 Coopervision International Limited Contact lens blister package with double layer foil component
EP4603484A2 (en) 2019-12-19 2025-08-20 Georgia State University Research Foundation, Inc. Compounds for the treatment of bacterial infections and potentiation of antibiotics
WO2021168320A1 (en) 2020-02-20 2021-08-26 Achillion Pharmaceuticals, Inc. Heteroaryl compounds for treatment of complement factor d mediated disorders
EP4216946A4 (en) 2020-09-23 2024-11-13 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement mediated disorders

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WO2005030305A1 (en) * 2003-09-26 2005-04-07 Innovata Biomed Limited Assembly for opening medicament containers, particularly containers for a powdered medicament
WO2009008001A2 (en) * 2007-04-30 2009-01-15 Sun Pharma Advanced Research Company Limited Inhalation device

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WO1999036116A1 (en) * 1998-01-15 1999-07-22 Pharmachemie B.V. Device for inhaling medicament
WO2005030305A1 (en) * 2003-09-26 2005-04-07 Innovata Biomed Limited Assembly for opening medicament containers, particularly containers for a powdered medicament
WO2009008001A2 (en) * 2007-04-30 2009-01-15 Sun Pharma Advanced Research Company Limited Inhalation device

Also Published As

Publication number Publication date
EA201100487A1 (ru) 2011-12-30
CL2011000789A1 (es) 2011-10-21
EA019293B1 (ru) 2014-02-28
EP2334358A4 (en) 2014-04-02
IL212074A0 (en) 2011-06-30
CA2738822A1 (en) 2010-04-15
AU2009302956B8 (en) 2012-09-27
MX2011003759A (es) 2011-05-03
US9095670B2 (en) 2015-08-04
BRPI0920658A2 (pt) 2016-01-12
ES2579902T3 (es) 2016-08-17
AU2009302956B2 (en) 2012-09-13
EP2334358A1 (en) 2011-06-22
EP2334358B1 (en) 2016-02-10
CN102245239A (zh) 2011-11-16
ZA201103334B (en) 2012-01-25
JP5518082B2 (ja) 2014-06-11
UA101056C2 (ru) 2013-02-25
US20120125330A1 (en) 2012-05-24
NZ591956A (en) 2012-11-30
JP2012505017A (ja) 2012-03-01
WO2010042033A1 (en) 2010-04-15
KR20110074766A (ko) 2011-07-01
AU2009302956A1 (en) 2010-04-15

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