CN102240373A

CN102240373A - Medicine for treating Cystitis

Info

Publication number: CN102240373A
Application number: CN2011101848796A
Authority: CN
Inventors: 冯素英
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-07-04
Filing date: 2011-07-04
Publication date: 2011-11-16

Abstract

A medicine for treating Cystitis. The preparation method of the medicine for treating Cystitis comprises the following steps of: decocting Smilax glabra Roxb, pyrrosia lingua, Melia azedarach, Ophicalcitum, Gentiana straminea Maxim, Fructus Gardeniae, Polyporus umbellatus, Chinese angelica, Alisma Orientalis, Poria cocos, Semen Plantaginis and Glycyrrhiza with water to obtain a water decoction, condensing and adding regular auxiliary materials, adding purified water until the crude drug amount is 1g/mL, filling and sterilizing to produce the oral liquid preparation. The medicine provided by the invention has functions of dispersing stagnated liver qi to promote bile flow, stopping dysthesia and expelling flatulence, and clearing heat and detoxicating, is used for treating Cystitis with high cure rate and low recurrence rate, has no side effect such as the harm of other Western medicine preparations to liver and kidney, and has no drug resistance of antibiotics. Through clinical observation, the effective rate of the medicine reaches 100%.

Description

A kind of medicine for the treatment of cystitis

Technical field

The present invention relates to a kind of medicine for the treatment of cystitis, particularly a kind of is the medicine of the treatment cystitis of crude drug preparation with Chinese medicine.

Background technology

Cystitis is a kind of commonly encountered diseases and frequently-occurring disease.Its clinical manifestation has acute and chronic two kinds, and the acute cystitis morbidity has burn feeling, and in urethral region pain arranged suddenly when urinating.Urgent micturition and serious frequent micturition are arranged sometimes.The very important point is that above-mentioned symptom had both betided night, occurs in daytime again, and the women is common, the time have gross hematuria and clot to discharge.It is weak unable that the patient feels, low grade fever is arranged, and also hyperpyrexia can be arranged, and do not accommodate lumbago and backache on the pubis, and physical examination has discomfort on the pubis sometimes, but do not have the waist tenderness.Concurrent epididymitis of male or urethritis, the concurrent pelvic inflammatory disease of women and easily outbreak repeatedly.

The symptom of chronic cystitis is similar to acute cystitis, but does not have hyperpyrexia, sustainable several weeks of symptom or intermittent attack, make the patient weak, become thin, waist and belly and the uncomfortable or dull pain of bladder perineal region appear, neurasthenia symptoms such as dizzy, dizzy appear sometimes.

Chronic cystitis is observed at cystoscope, can see that there is the edema inflammation neck of bladder and trigone of urinary bladder, and whole bladder presents the red and swollen mucosa of lamellar, and easily hemorrhage, mucosal ulcer appears in severe patient, is covered by exudate sometimes.Inflammatory cell is invaded and mucosa and flesh layer, becomes with fibroid, and bladder elasticity and capacity are reduced.

At present, general western medicine often produces dependency and side effect, and also has cure rate not high, and the problem that relapse rate is high is brought great misery to the patient, and brings terrified and worry from emotion, and the harm people ' s health is very serious.

Summary of the invention

The purpose of this invention is to provide a kind of medicine for the treatment of cystitis, this medicine depressed liver-energy dispersing and function of gallbladder promoting ends the tired therapeutic method to keep the adverse QI flowing downwards, heat-clearing and toxic substances removing, and treatment cystitis cure rate height, relapse rate is low.

Medicine of the present invention is that the crude drug by following parts by weight prepares:

Rhizoma Smilacis Glabrae 20---30 Folium Pyrrosiae 16---20

Melia azedarach L. 16---20 Ophicalcitum 20---30

Radix Gentianae Marcrophyllae 10---16 Fructus Gardeniae 12---20

Polyporus 12---20 Radix Angelicae Sinensis 12---20

Rhizoma Alismatis 12---18 Poria 12---20

Semen Plantaginis 10---16 Radix Glycyrrhizae 6---10.

Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is an oral liquid.

The concrete preparation method of above-mentioned each component being made medicine of the present invention is:

With above-mentioned medicaments in part by weight mix homogeneously, decoct with water 2-4 time, each 1-2 hour, collecting decoction, filter, filtrate is condensed into the clear paste of 70 ℃ of relative density 1.15-1.18, and cold preservation is left standstill, and gets supernatant liquid filtering, add conventional adjuvant in the filtrate, mixing, adding purified water is 1g/mL to containing the crude drug amount, oral liquid formulations is made in fill, sterilization.

Using method: oral, each 1, every 15mL, every day 3 times.

In the prescription of the present invention, Rhizoma Smilacis Glabrae, detoxifcation, dehumidifying, sharp joint; Folium Pyrrosiae ends the tired therapeutic method to keep the adverse QI flowing downwards, and logical bladder is full, mends five kinds of over strain, and An Wuzang removes aversion to wind, beneficial vital essence; Melia azedarach L., cold in nature, slightly poisonous, return, stomach, small intestinal, urinary bladder channel, the function promoting the circulation of QI to relieve pain, parasite killing is treated tinea; Ophicalcitum, acid, puckery, flat, nontoxic, blood stasis dispelling, hemostasis; Radix Gentianae Marcrophyllae, bitter dampness, the hot wind that looses, the heat of removing the intestines and stomach, the gas of the liver benefiting gallbladder, the flourish muscle that nourishes blood, sharp defecation; Fructus Gardeniae, pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Polyporus, sweet in the mouth, light is flat.Return kidney, urinary bladder channel, promoting diuresis to eliminate damp pathogen; Radix Angelicae Sinensis, warm in nature, ignorant sweet, hot, enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; Rhizoma Alismatis, sweet in the mouth, cold.Return kidney, urinary bladder channel, effect is a diuresis, clearing away damp-heat; Poria, slightly sweet flavor, property are flat, return through, GUIXIN, lung, spleen channel, effect: spleen invigorating, calm the nerves, calm, diuresis; Semen Plantaginis, sweet in flavor and cold in property, go into kidney, bladder, liver, lung meridian, function relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat-phlegm; The Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.More than all medicines share, altogether long memorial liver function of gallbladder promoting ends the tired therapeutic method to keep the adverse QI flowing downwards, the merit of heat-clearing and toxic substances removing is used for the treatment cure rate height of cystitis, relapse rate is low, does not have other Western medicine preparations to side reactions such as liver, renal damages, also the drug resistance of antibiotic-free etc.

For further investigating the clinical efficacy and the safety of medicine of the present invention, select 79 routine cystitis patients that the curative effect of medicine of the present invention is carried out clinical observation.

79 routine cases are divided into two groups at random.Matched group 34 examples, wherein, acute cystitis 16 examples, chronic cystitis 18 examples; 45 examples are organized in treatment, wherein, and acute cystitis 20 examples, chronic cystitis 25 examples.All cases are all made a definite diagnosis according to the diagnostic criteria diagnosis of cystitis in " new Chinese medicine clinical research guideline ".

Matched group adds sodium bicarbonate 1.0g with 2 of conventional Western medicine bactrims, every day 2 times, all takes continuously 3 days.The treatment group adopts medicine of the present invention to treat, and is oral, and each 1, every 15mL, every day 3 times.

Criterion of therapeutical effect: according in the clinical research guideline of urinary system infection " new Chinese medicine treatment " to the regulation of cystitis, 1. recovery from illness: the clinical symptoms sign disappears, it is normal that routine urianlysis recovers for 2 times, urine bacterium feminine gender, and in the 2nd, 6 week check urine bacterium 1 time, all negative, be recent healing, follow the trail of 6 months no recidivists for curing fully.2. produce effects: the clinical symptoms sign disappears or basic the disappearance, and routine urinalysis is normal or near normal, urine bacterium feminine gender.3. effective: the clinical symptoms sign alleviates, and routine urinalysis significantly improves, and urine is cultivated idol the positive.4. invalid: symptom and urine examination improve not obvious, and the quantitative check of urine bacterium is still positive, or the urine bacterium is positive and be same strain when the 2nd, 6 weeks checks.

Two groups of case treatment back curative effect comparative results see Table 1.

Table 1 liang group case treatment back curative effect relatively

Figure 2011101848796100002DEST_PATH_IMAGE001

Clinical experiment is the result prove, drug effect of the present invention obviously is better than matched group, do not see any untoward reaction.

The specific embodiment

Embodiment 1

The Poria 24Kg that fetches earth, Folium Pyrrosiae 18 Kg, Melia azedarach L. 17Kg, Ophicalcitum 25Kg, Radix Gentianae Marcrophyllae 12Kg, Fructus Gardeniae 19Kg, Polyporus 14Kg, Radix Angelicae Sinensis 17Kg, Rhizoma Alismatis 16Kg, Poria 17Kg, Semen Plantaginis 12Kg, Radix Glycyrrhizae 10Kg, clean with clear water, decoct with water 3 times, per 1 hour, collecting decoction, filter, be condensed into the clear paste of 70 ℃ of relative density 1.15-1.18, cold preservation is left standstill, and gets supernatant liquid filtering, add conventional adjuvant in the filtrate, mixing, adding purified water is 1g/mL to containing the crude drug amount, oral liquid formulations is made in fill, sterilization.

Embodiment 2

The Poria 27Kg that fetches earth, Folium Pyrrosiae 19 Kg, Melia azedarach L. 18Kg, Ophicalcitum 28Kg, Radix Gentianae Marcrophyllae 16Kg, Fructus Gardeniae 14Kg, Polyporus 18Kg, Radix Angelicae Sinensis 14Kg, Rhizoma Alismatis 13Kg, Poria 14Kg, Semen Plantaginis 15Kg, Radix Glycyrrhizae 8Kg, clean with clear water, decoct with water 3 times, per 1 hour, collecting decoction, filter, be condensed into the clear paste of 70 ℃ of relative density 1.15-1.18, cold preservation is left standstill, and gets supernatant liquid filtering, add conventional adjuvant in the filtrate, mixing, adding purified water is 1g/mL to containing the crude drug amount, oral liquid formulations is made in fill, sterilization.

Claims

1. medicine for the treatment of cystitis is that crude drug prepares by the Chinese medicine of following portions by weight:

Rhizoma Smilacis Glabrae 20---30 Folium Pyrrosiae 16---20

Melia azedarach L. 16---20 Ophicalcitum 20---30

Radix Gentianae Marcrophyllae 10---16 Fructus Gardeniae 12---20

Polyporus 12---20 Radix Angelicae Sinensis 12---20

Rhizoma Alismatis 12---18 Poria 12---20

Semen Plantaginis 10---16 Radix Glycyrrhizae 6---10.

2. the medicine of treatment cystitis according to claim 1 is characterized in that described crude drug is made oral liquid.

3. according to the preparation method of the medicine of the described treatment cystitis of claim 2, be, decoct with water 2-4 time the crude drug mix homogeneously of above-mentioned parts by weight, each 1-2 hour, collecting decoction filters, and filtrate is condensed into the clear paste of 70 ℃ of relative density 1.15-1.18, cold preservation is left standstill, get supernatant liquid filtering, add conventional adjuvant, mixing in the filtrate, adding purified water is 1g/mL to containing the crude drug amount, and oral liquid formulations is made in fill, sterilization.