CN101112497A - Medicine for treating prostatitis and method for preparing the same - Google Patents

Medicine for treating prostatitis and method for preparing the same Download PDF

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Publication number
CN101112497A
CN101112497A CNA2007101392626A CN200710139262A CN101112497A CN 101112497 A CN101112497 A CN 101112497A CN A2007101392626 A CNA2007101392626 A CN A2007101392626A CN 200710139262 A CN200710139262 A CN 200710139262A CN 101112497 A CN101112497 A CN 101112497A
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radix
rhizoma
medicine
treatment
cortex phellodendri
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CN100556434C (en
Inventor
饶长根
赵生芳
张京平
郝敏
李育民
樊水琴
谢桂凤
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Second Hospital of Shanxi Medical University
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Second Hospital of Shanxi Medical University
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Abstract

The present invention relates to a drug for treating prostatitis; the white paeony root, combined spicebush root, yanhusuo, Szechwan Chinaberry fruit etc. are mixed and smashed into fine powder, the water is added in radix rehmanniae glutinosae, Yunnan manyleaf Paris rhizome, glabrous greenbrier rhizome, rhizoma dioscoreae hypoglaucae, himalayan teasel root and other medicines for boiling, after the medicines are filtered and condensed into the clear paste, the medicine powder is added for even mixing, smashed and filled in the capsule, and then the product is obtained. The drug of the present invention has the effects of clearing heat, cooling blood, regulating qi, eliminating phlegm, relieving spasm and stopping pain, which can be used for the treatment of chronic prostatitis, prostate pain, urethral syndrome, pelvic congestion syndrome and pelvic inflammatory disease; the total effective rate can reach 84.4 percent through the clinical efficacy observations of 90 cases of patients with chronic prostatitis.

Description

Prostatitic medicine of a kind of treatment and preparation method thereof
Technical field
The present invention relates to the prostatitic medicine of a kind of treatment, particularly relating to a kind of is the prostatitic medicine of treatment of feedstock production with Chinese medicine.The invention still further relates to the preparation method of this medicine.
Background technology
Chronic prostatitis is a kind of good sending out in male adults, serves as the disease of main performance unusually with lower urinary tract symptom, prostate tenderness and massage of prostate liquid.Its pathogenic factor complexity, can because of often by bike, overworked, drink, factors such as sexual repression or fleshliness cause pelvic congestion, qi depression to blood stasis, cause that few abdomen, perineum, testis etc. locate the pain bloated sexual dysfunction of spraining, sick body of prostate proliferation of fibrous tissue for a long time, body of gland hardening, glandular tube blocks, and glandular secretion is lowered or lost its secretory function, causes frequent micturition, dysurea, lumbago, lower abdomen weighs down and expands, orchiodynia, male's libido lowers, sexual impotence, symptoms such as premature ejaculation.Primary disease belongs to the category of Chinese medicine " smart turbid ", " stranguria caused by overstrain ".
In Drug therapy, run into following thorny problem at present both at home and abroad to chronic prostatitis:
1, because the prostatic special physiological region of anatomy, have capsula prostatica to surround the prostate body of gland, peplos is hard and thick, general in, western drug is difficult to penetrate rupture of membranes, weakens therapeutic effect, so non-simple anti-inflammation can prove effective, treatment is difficult.
Though it is direct, rapid-action 2, directly to use medicine ion to penetrate the contrary filling method curative effect of method or per urethra, operation inconvenience causes bleeding easily, causes double infection and forms rhabdion, and seondary effect is many.
3, prostatitis state of an illness complexity, touching difficulty heal, recur easily.General medicine only has therapeutic effect to a kind of disease type, and to another disease type DeGrain.
Summary of the invention
The purpose of this invention is to provide a kind of prostatitic medicine that is used for the treatment of, this medicine has heat clearing away, removing heat from blood, regulate the flow of vital energy eliminate the phlegm, slow convulsion analgesic effect, can be used for treating diseases such as chronic prostatitis, prostatodynia, urethra symptom group, pelvic congestion syndrome, pelvic inflammatory disease.
A kind of manufacturing method for above mentioned medicine is provided, and is another goal of the invention of the present invention.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Radix Rehmanniae 40~50 Radix Paeoniae Albas 15~20
Rhizoma Paridis 15~20 Rhizoma Smilacis Glabraes 15~20
Rhizoma Dioscoreae Hypoglaucae 15~20 Radix Salviae Miltiorrhizaes 15~20
Radix Dipsaci 15~20 Radix Bupleuri 8~10
The Radix Linderae 15~20 Rhizoma Cyperis 15~20
Rhizoma Corydalis 15~20 Fructus Toosendans 15~20
Semen Citri Reticulatae 8~10 Oletum Trogopteroris 8~10
Pollen Typhae 8~10 Myrrhas 8~10
Cortex Phellodendri 15~20 Radix Et Rhizoma Rhei 5~10
Rhizoma Chuanxiong 8~10.
The medicine of above-mentioned each component can be made said dosage form on any pharmaceutics, and the preferred dosage form of the present invention is a capsule.
The concrete preparation method of said medicine being made capsule of the present invention is:
According to above-mentioned parts by weight, get the Radix Paeoniae Alba, the Radix Linderae, Rhizoma Corydalis, Fructus Toosendan and part Cortex Phellodendri, Radix Et Rhizoma Rhei mix homogeneously after, be ground into 80~100 purpose fine powders; Residue Cortex Phellodendri, Radix Et Rhizoma Rhei and all the other medicines decoct with water 3 times, and each 0.5~1 hour, merge 3 times decocting liquid, being condensed into relative density is the clear paste of 1.12 (50 ℃); The said medicine fine powder is added mix homogeneously in the clear paste, after 50~60 ℃ of dryings, be ground into 100~120 purpose medicated powder, sterilization makes the capsule product in incapsulating.
In the prescription of the present invention, Radix Rehmanniae clearing away heat and cooling blood, yin nourishing are promoted the production of body fluid; The Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire; The Rhizoma Paridis heat-clearing and toxic substances removing, reducing swelling and alleviating pain, cool liver arresting convulsion; The Rhizoma Smilacis Glabrae dehumidifying, detoxifcation, easing joint movement; The Rhizoma Dioscoreae Hypoglaucae dampness removing goes turbid, and eliminating impediment dispels the wind; The Radix Dipsaci invigorating the liver and kidney, bone and muscle strengthening, continuous folding is hindered, and ends metrorrhagia; The Radix Bupleuri reconciling superficies and interior, soothing the liver, yang invigorating; The Rhizoma Cyperi promoting QI circulation for relieving depression, menstruction regulating and pain relieving; Semen Citri Reticulatae is regulated the flow of vital energy, eliminating stagnation, pain relieving; The Pollen Typhae hemostasis, blood stasis dispelling, treating stranguria; Cortex Phellodendri heat clearing and damp drying, pathogenic fire purging are removed and are steamed, and skin ulcer is treated in detoxifcation; The Radix Et Rhizoma Rhei purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation; The Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping; The pain relieving of Radix Paeoniae Alba suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating; The pleasant pain relieving of the Radix Linderae, warming kidney for dispelling cold; Rhizoma Corydalis is invigorated blood circulation, promoting the circulation of QI, pain relieving; Fructus Toosendan soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.Full side share, play clearing away heat and cooling blood altogether, regulate the flow of vital energy eliminate the phlegm, slow convulsion analgesic effect, can be used for treating symptoms such as chronic prostatitis, prostatodynia, urethra symptom group, pelvic congestion syndrome, pelvic inflammatory disease.
For further investigating the clinical efficacy and the safety of medicine of the present invention, Second Hospital of Shanxi Medical University selects 90 routine patients with chronic prostatitis that the curative effect of medicine of the present invention has been carried out clinical observation.
In the 90 routine patients with chronic prostatitis, 20~45 years old age, the course of disease 3 months~10 years.Choice criteria is: 1. obvious clinical symptoms is arranged, comprise frequent micturition, lower abdomen, groin, testis, perineum, waist front portion sprain bloated, pain or sexual dysfunction etc.; 2. the prostate touch and before draw gland liquid routine examination 80 routine leukocyte count>10/HP; 3. prostatic fluid antibacterial culturing, 30 routine antibacterial culturing 19 examples are positive; 4. the prostate ultrasound diagnosis shows that echo is inhomogeneous, and peplos is irregular; 5. the 35 examples patient that once used multiple antibacterials or QIANLIEKANG, NANKANG, physical therapy sealing etc. to fail to respond to any medical treatment wherein.
Therapeutic Method
The oral GONGXUENING JIAONANG of producing of matched group by Yunnan Paiyao Group Corp., Ltd, 3 times on the one, each 2.Oral medicine of the present invention is organized in treatment, and 3 times on the one, each 4.1 week was 1 course of treatment, observed two groups of patient's traditional Chinese medical science diseases after 2 courses of treatment and improved situation, adopted symptom and sign integration method overall merit curative effect.
Therapeutic Method
Oral medicine of the present invention, every day 3 times, each 4.4 weeks were 1 course of treatment.Period in a medicine other treatment of stopping using is avoided and is drunk and raw food stimulates food, notes the sexual life rule, cooperates psychological counseling.
Criterion of therapeutical effect
Cure: subjective symptoms disappears, and it is normal that prostatic fluid recovers;
Effectively: subjective symptoms is clearly better, and prostatic fluid is near normal;
Invalid: subjective symptoms does not have improvement or take a favorable turn slightly, and prostatic fluid does not have significant change.
Observation of curative effect
Through the treatment of 1~3 course of treatment, cure 36 examples among the 90 routine patients, account for 40%; Effective 40 examples account for 44.4%; Invalid 14 examples account for 15.6%, and total effective rate accounts for 84.4%.Do not find any untoward reaction and other side effect during the medication.
Clinical observation on the therapeutic effect proof medicine of the present invention has remarkable result for eliminating clinical symptoms, and local metabolism of the prostate of improvement or blood circulation are arranged, and improves the effect of the disease-resistant and repair function of prostate and has certain antibacterial and anti-inflammation functions.
Through preliminary observation, medicine of the present invention except that to draw before chronic adenitis effectively, pelvic congestion syndrome, female urethra symptom group, sexual dysfunction etc. are also had certain effect.
The specific embodiment
Embodiment 1
Get Radix Paeoniae Alba 350g, after Radix Linderae 350g, Rhizoma Corydalis 400g, Fructus Toosendan 400g, Cortex Phellodendri 200g, Radix Et Rhizoma Rhei 75g chose most impurity, screening and clean and to dry, it is standby that mixed powder is broken into 80 order fine powders.
With Radix Rehmanniae 1000g, Rhizoma Paridis 350g, Rhizoma Smilacis Glabrae 400g, Rhizoma Dioscoreae Hypoglaucae 400g, Radix Salviae Miltiorrhizae 400g, Radix Dipsaci 400g, Radix Bupleuri 150g, Rhizoma Cyperi 400g, Semen Citri Reticulatae 150g, Oletum Trogopterori 150g, Pollen Typhae 150g, Myrrha 150g, Cortex Phellodendri 200g, Radix Et Rhizoma Rhei 75g, Rhizoma Chuanxiong 150g joins in the 9L water and decocts, medicinal residues add same water gaging again and decoct 2 times, and the 1st, 2 time each 1 hour, the 3rd time 45 minutes, merge 3 times decocting liquid, filter, be condensed into the clear paste of relative density 1.12 (50 ℃).
Add the said medicine fine powder in the clear paste, mix homogeneously after 60 ℃ of dryings, is ground into 120 purpose medicated powder, and sterilization makes the capsule product in incapsulating.
Embodiment 2
Get Radix Paeoniae Alba 400g, after Radix Linderae 400g, Rhizoma Corydalis 300g, Fructus Toosendan 300g, Cortex Phellodendri 150g, Radix Et Rhizoma Rhei 90g chose most impurity, screening and clean and to dry, it is standby that mixed powder is broken into 80 order fine powders.
With Radix Rehmanniae 900g, Rhizoma Paridis 400g, Rhizoma Smilacis Glabrae 300g, Rhizoma Dioscoreae Hypoglaucae 300g, Radix Salviae Miltiorrhizae 300g, Radix Dipsaci 300g, Radix Bupleuri 200g, Rhizoma Cyperi 300g, Semen Citri Reticulatae 200g, Oletum Trogopterori 200g, Pollen Typhae 200g, Myrrha 200g, Cortex Phellodendri 150g, Radix Et Rhizoma Rhei 90g, Rhizoma Chuanxiong 200g joins in the 9L water and decocts, medicinal residues add same water gaging again and decoct 2 times, and the 1st, 2 time each 1 hour, the 3rd time 45 minutes, merge 3 times decocting liquid, filter, be condensed into the clear paste of relative density 1.12 (50 ℃).
Add the said medicine fine powder in the clear paste, mix homogeneously after 60 ℃ of dryings, is ground into 120 purpose medicated powder, and sterilization makes the capsule product in incapsulating.
Embodiment 3
Get Radix Paeoniae Alba 300g, after Radix Linderae 300g, Rhizoma Corydalis 300g, Fructus Toosendan 300g, Cortex Phellodendri 150g, Radix Et Rhizoma Rhei 100g chose most impurity, screening and clean and to dry, it is standby that mixed powder is broken into 100 order fine powders.
With Radix Rehmanniae 1000g, Rhizoma Paridis 300g, Rhizoma Smilacis Glabrae 300g, Rhizoma Dioscoreae Hypoglaucae 300g, Radix Salviae Miltiorrhizae 300g, Radix Dipsaci 300g, Radix Bupleuri 200g, Rhizoma Cyperi 300g, Semen Citri Reticulatae 200g, Oletum Trogopterori 200g, Pollen Typhae 200g, Myrrha 200g, Cortex Phellodendri 150g, Radix Et Rhizoma Rhei 100g, Rhizoma Chuanxiong 200g joins in the 9L water and decocts, medicinal residues add same water gaging again and decoct 2 times, and the 1st, 2 time each 1 hour, the 3rd time 45 minutes, merge 3 times decocting liquid, filter, be condensed into the clear paste of relative density 1.12 (50 ℃).
Add the said medicine fine powder in the clear paste, mix homogeneously after 60 ℃ of dryings, is ground into 100 purpose medicated powder, and sterilization makes the capsule product in incapsulating.
Embodiment 4
Get Radix Paeoniae Alba 400g, after Radix Linderae 400g, Rhizoma Corydalis 350g, Fructus Toosendan 350g, Cortex Phellodendri 175g, Radix Et Rhizoma Rhei 90g chose most impurity, screening and clean and to dry, it is standby that mixed powder is broken into 100 order fine powders.
With Radix Rehmanniae 800g, Rhizoma Paridis 400g, Rhizoma Smilacis Glabrae 350g, Rhizoma Dioscoreae Hypoglaucae 350g, Radix Salviae Miltiorrhizae 350g, Radix Dipsaci 350g, Radix Bupleuri 200g, Rhizoma Cyperi 350g, Semen Citri Reticulatae 200g, Oletum Trogopterori 200g, Pollen Typhae 200g, Myrrha 200g, Cortex Phellodendri 175g, Radix Et Rhizoma Rhei 90g, Rhizoma Chuanxiong 200g joins in the 9L water and decocts, medicinal residues add same water gaging again and decoct 2 times, and the 1st, 2 time each 1 hour, the 3rd time 45 minutes, merge 3 times decocting liquid, filter, be condensed into the clear paste of relative density 1.12 (50 ℃).
Add the said medicine fine powder in the clear paste, mix homogeneously after 50 ℃ of dryings, is ground into 100 purpose medicated powder, and sterilization makes the capsule product in incapsulating.

Claims (3)

1. prostatitic medicine of treatment is that crude drug prepares by the Chinese medicine of following portions by weight:
Radix Rehmanniae 40~50 Radix Paeoniae Albas 15~20
Rhizoma Paridis 15~20 Rhizoma Smilacis Glabraes 15~20
Rhizoma Dioscoreae Hypoglaucae 15~20 Radix Salviae Miltiorrhizaes 15~20
Radix Dipsaci 15~20 Radix Bupleuri 8~10
The Radix Linderae 15~20 Rhizoma Cyperis 15~20
Rhizoma Corydalis 15~20 Fructus Toosendans 15~20
Semen Citri Reticulatae 8~10 Oletum Trogopteroris 8~10
Pollen Typhae 8~10 Myrrhas 8~10
Cortex Phellodendri 15~20 Radix Et Rhizoma Rhei 5~10
Rhizoma Chuanxiong 8~10.
2. the prostatitic medicine of treatment according to claim 1 is characterized in that described medicine is made capsule.
3. the preparation method of the described treatment prostatitis of claim 2 medicine is characterized in that according to above-mentioned parts by weight, get the Radix Paeoniae Alba, the Radix Linderae, Rhizoma Corydalis, Fructus Toosendan and part Cortex Phellodendri, Radix Et Rhizoma Rhei mix homogeneously after, be ground into 80~100 purpose fine powders; Residue Cortex Phellodendri, Radix Et Rhizoma Rhei and all the other medicines decoct with water 3 times, and each 0.5~1 hour, merge 3 times decocting liquid, being condensed into relative density is the clear paste of 1.12 (50 ℃); The said medicine fine powder is added mix homogeneously in the clear paste, after 50~60 ℃ of dryings, be ground into 100~120 purpose medicated powder, sterilization makes the capsule product in incapsulating.
CNB2007101392626A 2007-08-20 2007-08-20 Prostatitic medicine of a kind of treatment and preparation method thereof Expired - Fee Related CN100556434C (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104971308A (en) * 2015-06-29 2015-10-14 贝忠东 Traditional Chinese medicine composition for treating chronic prostatitis
CN105434633A (en) * 2014-08-27 2016-03-30 李东海 A medicine for treating prostatitis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1124153C (en) * 2001-08-31 2003-10-15 石家庄以岭药业股份有限公司 Medicinal composition for restoring cardiac collaterals and its application

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105434633A (en) * 2014-08-27 2016-03-30 李东海 A medicine for treating prostatitis
CN104971308A (en) * 2015-06-29 2015-10-14 贝忠东 Traditional Chinese medicine composition for treating chronic prostatitis

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