CN102228418A - Cosmetic for keeping skin health and beauty and preparation method thereof - Google Patents

Cosmetic for keeping skin health and beauty and preparation method thereof Download PDF

Info

Publication number
CN102228418A
CN102228418A CN 201110176714 CN201110176714A CN102228418A CN 102228418 A CN102228418 A CN 102228418A CN 201110176714 CN201110176714 CN 201110176714 CN 201110176714 A CN201110176714 A CN 201110176714A CN 102228418 A CN102228418 A CN 102228418A
Authority
CN
China
Prior art keywords
add
deionized water
cooled
cosmetics
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN 201110176714
Other languages
Chinese (zh)
Other versions
CN102228418B (en
Inventor
焦家良
宋普球
李岚
陈刚
灵晓燕
焦少良
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yunnan Longfa pharmaceutical Limited by Share Ltd
Original Assignee
Yunnan Longrun Tea Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yunnan Longrun Tea Group Co Ltd filed Critical Yunnan Longrun Tea Group Co Ltd
Priority to CN 201110176714 priority Critical patent/CN102228418B/en
Publication of CN102228418A publication Critical patent/CN102228418A/en
Application granted granted Critical
Publication of CN102228418B publication Critical patent/CN102228418B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Cosmetics (AREA)

Abstract

The invention relates to a cosmetic for keeping skin health and beauty and a preparation method thereof. The cosmetic is prepared by the following raw materials by weight: 3-6% of catechin, 2-5% of coenzyme Q10, 1-3% of Phyllanthus emblica juice, 0-4% of ultraviolet absorber, 1-3.5% of emulsifier, 7-12% of moisturizer, 0.01-0.03% of preservative, 3-8% of nutritional components, and the balance deionized water. The ultraviolet absorber consists of superfine titanium dioxide powder (titanium white powder) and superfine zinc oxide. The nutritional components include a Baicalin extract, a Saussurea extract, aloe extract, a ganoderma extract and one or more types of Vitamin E. The cosmetic of the invention can eliminate superoxide free radicals of skin, tranquilize and soothe skin effectively, enhance skin resistance to external severe environment, and promote skin health and beauty.

Description

A kind of cosmetics that keep skin fitness and preparation method thereof
Technical field
The invention belongs to the cosmetics technical field, particularly a kind of cosmetics that keep skin fitness and preparation method thereof.
Background technology
Ultraviolet by the wavelength difference be divided into ultraviolet light,long wave (UVA, 320nm-400nm), UV-B (UVB, 290nm-320nm), ultraviolet C (UVC, 200nm-290nm).During UVC process stratosphere, absorbed by ozone layer, do not enter ground; And UVB shines skin for a long time and can suppress skin mitosis and DNA, RNA, protein synthesis, causes the biomolecule fracture, causes that DNA burst skin carcinoma, skin occur that erythema swells and ache, inflammation, skin aging, even skin carcinoma; It is irreversible that UVA can reach deep dermis, causes the dermal melanin calmness, makes the skin tanning canceration, increases the infringement of UVB to skin.
Resist ultraviolet product and mainly contain three kinds: 1. ultraviolet light screener, as titanium dioxide, zinc oxide, exist transparent feel poor, easily fall, stop up pore, influence sweat gland secretion even cause dermopathic shortcoming at the skin surface deposition pull-up that is white in color; 2. ultraviolet absorber, as para-amino benzoic acid derivant, o-aminobenzoa derivant, cinnamate derivative, salicylic acid esters, Benzophenones chemical compound, camphor derivatives, methane Derivatives, bigcatkin willow vinegar class, to methoxyl group carnic acid vinegar class etc., the tool zest that has easily causes symptoms such as scytitis, allergy; 3. natural sun-prevention agent is as Aloe extract, Fructus Cucumidis sativi extract, Radix Scutellariae extract, Flos Sophorae extract, Oleum Hippophae, Rhizoma Kaempferiae extract, Herba Saussureae Involueratae extract, Rhizoma Curcumae Longae extract etc.Natural sun-prevention agent performance gentleness, non-stimulated to skin, can under safe and harmless prerequisite, bring into play integrated protection effects such as opposing ultraviolet, antioxidation, antiinflammatory, meet the development trend of green cosmetics.If yet natural extract can not guarantee effectively that its active component is not oxidized, will greatly reduce the result of use of product, allow easily it is believed that the notion that plant extract is just arranged, still there is not the product of actual effect.Therefore the cosmetics made by good proportioning of all kinds of prescriptions are only and meet market demands, and are constantly progressive, have the product of vitality.
Summary of the invention
The purpose of this invention is to provide a kind of cosmetics that keep skin fitness and preparation method thereof.
Cosmetics main component of the present invention is that catechin, coenzyme Q10 and Yunnan Sucus Canarii albi are formed, and adds necessary auxiliary material and makes cosmetics such as astringent, emulsion, frost, ultra light sun block lotion.The weight proportion of its raw material is:
Catechin 3-6%, coenzyme Q10 2-5%, Sucus Phyllanthi (Yunnan Fructus Canarii albi) 1-3%, ultraviolet absorber 0-4%, emulsifying agent 1-3.5%, wetting agent 7-12%, antiseptic 0.01-0.03%, nutritional labeling 3-8%, deionized water adds to 100%; Ultraviolet absorber is superfine titanic oxide powder (titanium dioxide), super fine zinc oxide; Nutritional labeling is one or more in Radix Scutellariae glucoside extract, Herba Saussureae Involueratae extract, Aloe extraction solution, Ganoderma extract, the vitamin E.
Emulsifying agent in the product is lecithin, Brij92, single Tryfac 5573 MAP, TWEEN 80, hexadecanol, glyceryl monostearate, glyceryl stearate, octadecanol, lanolin alcohol, Fructus Citri Limoniae alcohol, coconut monoethanolamide, spermaceti ricinoleate, crosslinked polypropylene diluted acid resin, one or more in the aminoacid Laurel alcohol ester etc.
Wetting agent in the product is, glycerol, butanediol, sorbitol Squalene, Jojoba oil, hyaluronic acid, ceramide, silk peptide protide, collagen egg, pyrrolidone sodium carboxylate PCA-Na, mucopolysaccharide-glass aldehydic acid sodium, pantothenylol, betanin, maltose, carbamide, chitin, Polyethylene Glycol, one or more in waiting.
Antiseptic in the product is triumphant pine, Bronopol, propyl p-hydroxybenzoate, Butylated hydroxyanisole, tert-butyl group hydroxy-methylbenzene, one or more in the propyl gallate etc.
Catechin comes from Folium Camelliae sinensis extract and handles and get through decaffeination and recrystallization, mainly comprises epicatechin EC, epigallo catechin EGC, L-Epicatechin gallate ECG and epigallocatechin gallate (EGCG) EGCG.Functions such as catechin has photoprotection to ultraviolet radiation, removes the oxygen-derived free radicals antioxidation, preserves moisture, slow down aging, anti-inflammation anti-acne, antiallergic, anti-gene mutation, enhance immunity.Coenzyme Q10 has another name called Ubidecarenone, is present in the mitochondrial inner membrane of cell, and energy free radical resisting, antioxidation replenish the skin collagen protein, wake the smooth and elastic force of skin up, and anti-wrinkle and microgroove improve immunity, delaying skin aging.The Yunnan Fructus Canarii albi claims Fructus Phyllanthi again, contains abundant vitamin C and quasi-SOD material, has free radical, antioxidation and the whitening function of removing.The present invention combines catechin, coenzyme Q10 and Yunnan Sucus Canarii albi first, gives full play to their function, effects such as catechin tool antioxidation, radioprotective, the V in coenzyme Q10 and the Yunnan Sucus Canarii albi CCan strengthen the function of catechin greatly with SOD; play synergism activating phosphatase tyrosine kinase, prevent the DNA oxidative damage, suppress skin fibroblast collagen protein expression of enzymes; thereby keep the vigorous metabolism of skin, it is healthy to protect effectively that skin and muscles are fair in the adverse circumstances.And catechin and UV absorbent use simultaneously, and dimension C and catechin synergism be the skin damage brought of maintenance ultraviolet effectively, and the adding of above three kinds of main components is intended to optimize the cosmetic composition proportion.Promote the cost performance of cosmetics.
The present invention has the following advantages:
1) cosmetic material of the present invention is selected rationally, and processing technology is simple and practical.
2) cosmetics performance gentleness of the present invention, clearly comfortable, be a kind ofly collect uvioresistant, antioxidation, pore refining, antibiotic, antiinflammatory anti-acne, degrease, radioprotective, antiallergic, preserve moisture, slow down aging, lifting is smooth and elastic force, anti-wrinkle and multiple functions such as microgroove, removing free radical are the cosmetics of one.
3) cosmetics of the present invention are main component with the natural plant extracts, the V in coenzyme Q10 and the Fructus Phyllanthi (Yunnan Fructus Canarii albi) C, SOD can help catechin to prevent the DNA oxidative damage, keeps the vigorous metabolism of skin, protection skin is avoided damage, skin whitening; soft and smooth careful, the delicate gloss of skin behind these cosmetics of life-time service; but delaying decrepitude of skin, the various skins that are fit to each age use.The adding of catechin can reduce the use of the antiseptic of chemosynthesis.
The specific embodiment
The preparation of Fructus Phyllanthi (Yunnan Fructus Canarii albi) juice: with squeezer squeezing Yunnan Fructus Canarii albi fresh fruit, the juice that obtains leave standstill 2-6 hour, cross the filtering precipitation and get final product.
Embodiment 1: the preparation of suntan lotion (0/W)
Figure 957302DEST_PATH_IMAGE001
Concrete preparation method may further comprise the steps:
1) in containing the reactor of deionized water, add entry by proportioning, butanediol, lecithin and aminoacid Laurel alcohol ester slowly stir and are warming up to 70-90 ℃; Add titanium dioxide powder then, zinc oxide stirs and makes its mix homogeneously;
2) be cooled to 50-60 ℃ and add the antiseptic Butylated hydroxyanisole, catechin continues cooling after coenzyme Q10 stirs;
3) be cooled to 40-45 ℃ and add Sucus Phyllanthi, Aloe extraction solution continues to stir;
4) add deionized water to 100%, after stirring, be cooled to 38 ℃ of dischargings and promptly get suntan lotion (0/W).
 
Embodiment 2: the preparation of emulsion (0/W)
Figure 812126DEST_PATH_IMAGE002
Preparation method may further comprise the steps:
1) in containing the reactor of deionized water, adds lecithin, glyceryl monostearate and hyaluronic acid, slowly stir and be warming up to 70-90 ℃ by proportioning.
2) be cooled to 50 ℃ and add catechin, coenzyme Q10 and propyl p-hydroxybenzoate, cooling is continued in the back that stirs.
3) be cooled to 40 ℃-45 ℃ and add Sucus Phyllanthi, Radix Scutellariae glucoside extract, continue to stir.
4) add deionized water add to 100% stir after, fully cooling back discharging.
Embodiment 3: the preparation of emulsion (W/O)
Figure 591863DEST_PATH_IMAGE003
Concrete preparation method may further comprise the steps:
1) adding glyceryl stearate and hyaluronic acid by proportioning in containing the reactor of deionized water slowly stirs and is warming up to 70-90 ℃.
2) be cooled to 50 ℃ of adding catechins, coenzyme Q10 and an amount of propyl gallate stirring and make evenly back continuation cooling of system.
3) be cooled to 40 ℃-45 ℃ and add Sucus Phyllanthi, vitamin E, continue to stir.
4) add deionized water to total amount, after stirring, fully cooling back discharging.
Embodiment 4: the preparation of astringent
Concrete preparation method may further comprise the steps:
1) add glycerol by proportioning in containing the reactor of deionized water, hyaluronic acid, Brij92 are heated to 70-90 ℃
2) be cooled to 50-60 ℃ and add catechin, coenzyme Q10 and tert-butyl group hydroxy-methylbenzene, cooling is continued in the back that stirs;
3) be cooled to 40 ℃-45 ℃ and add Sucus Phyllanthi, Herba Saussureae Involueratae extract continuation stirring;
4) add deionized water to 100%, after stirring, fully the cooling back-5-10 ℃ freezing down, filter, make astringent after getting clear liquid.
Above-described extract is prior art.
Cosmetics collection uvioresistant of the present invention, antioxidation, pore refining, antibiotic, antiinflammatory anti-acne, degrease, radioprotective, antiallergic, removal superabundant fats, preserve moisture, slow down aging, lifting is smooth with elastic force, prevention and repair wrinkle and multiple functions such as microgroove, removing free radical are one, the V in coenzyme Q10 and the Yunnan Fructus Canarii albi C, SOD can help catechin to prevent the DNA oxidative damage, keeps the vigorous metabolism of skin, protection skin is avoided damage, skin whitening; can effectively remove the infringement of ultraviolet after the long-term complete use to skin; repair skin; strengthen the immunity of skin, protection skin health beauty from hostile environment.
The invention is not restricted to above most preferred embodiment, all distortion that anyone directly draws under enlightenment of the present invention all should be in protection scope of the present invention.

Claims (5)

1. cosmetics that keep skin fitness is characterized in that the weight proportion of raw material is: catechin 3-6%, coenzyme Q10 2-5%, Sucus Phyllanthi 1-3%, ultraviolet absorber 0-4%, emulsifying agent 1-3.5%, wetting agent 7-12%, antiseptic 0.01-0.03%, nutritional labeling 3-8%, deionized water adds to 100%; Ultraviolet absorber is superfine titanic oxide powder (titanium dioxide), super fine zinc oxide; Nutritional labeling is one or more in Radix Scutellariae glucoside extract, Herba Saussureae Involueratae extract, Aloe extraction solution, Ganoderma extract, the vitamin E.
2. the cosmetics of maintenance skin fitness according to claim 1 is characterized in that described cosmetics are suntan lotion, facial treatment milk and astringent product.
3. the preparation method of ultra light sun block lotion in the cosmetics of the described maintenance skin fitness of claim 1 is characterized in that carrying out according to the following steps:
1) in containing the reactor of deionized water, adds entry, wetting agent and emulsifying agent, slowly stir and be warming up to 70-90 ℃ by proportioning; Add titanium dioxide powder then, zinc oxide stirs and makes its mix homogeneously;
2) be cooled to 50-60 ℃ and add catechin, continue cooling after coenzyme Q10, antiseptic stir;
3) be cooled to 40-45 ℃ and add Sucus Phyllanthi, nutritional labeling continuation stirring;
4) add deionized water to 100%, after stirring, be cooled to 38 ℃ of dischargings and promptly get suntan lotion.
4. the preparation method of emulsion in the cosmetics of the described maintenance skin fitness of claim 1 is characterized in that carrying out according to the following steps:
1) adding emulsifying agent and wetting agent by proportioning in containing the reactor of deionized water slowly stirs and is warming up to 70-90 ℃;
2) be cooled to 50-60 ℃ and add catechin, coenzyme Q10 and antiseptic, cooling is continued in the back that stirs;
3) be cooled to 40 ℃-45 ℃ and add Sucus Phyllanthi, nutritional labeling continuation stirring;
4) add deionized water to 100%, after stirring, fully cooling back discharging obtains facial treatment milk.
5. the preparation method of the cosmetics of the described maintenance skin fitness of claim 1 is characterized in that carrying out according to the following steps:
1) in containing the reactor of deionized water, adds heat preserving agent, emulsifying agent, slowly stir and heat to 70-90 ℃ by proportioning;
2) be cooled to 50-60 ℃ and add catechin, coenzyme Q10 and antiseptic, cooling is continued in the back that stirs;
3) be cooled to 40 ℃-45 ℃ and add Sucus Phyllanthi, nutritional labeling continuation stirring;
4) add deionized water to 100%, after stirring, fully the cooling back-5-10 ℃ freezing down, filter, make astringent after getting clear liquid.
CN 201110176714 2011-06-28 2011-06-28 Cosmetic for keeping skin health and beauty and preparation method thereof Active CN102228418B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201110176714 CN102228418B (en) 2011-06-28 2011-06-28 Cosmetic for keeping skin health and beauty and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201110176714 CN102228418B (en) 2011-06-28 2011-06-28 Cosmetic for keeping skin health and beauty and preparation method thereof

Publications (2)

Publication Number Publication Date
CN102228418A true CN102228418A (en) 2011-11-02
CN102228418B CN102228418B (en) 2013-03-20

Family

ID=44841053

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 201110176714 Active CN102228418B (en) 2011-06-28 2011-06-28 Cosmetic for keeping skin health and beauty and preparation method thereof

Country Status (1)

Country Link
CN (1) CN102228418B (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102784075A (en) * 2012-08-22 2012-11-21 中国农业科学院茶叶研究所 Sunscreen containing catechuic acid acetylated derivative
CN103432014A (en) * 2013-08-24 2013-12-11 上海艳紫化工科技有限公司 Catechin skin cream
CN104398451A (en) * 2014-11-14 2015-03-11 成都鹏翔生物科技有限公司 Moisture-retaining skin-care emulsion containing chestnut extractive and preparation method thereof
CN104490681A (en) * 2014-12-10 2015-04-08 唯美度科技(北京)有限公司 Skin softening cream capable of forming multiple sun screens
EP2859896A1 (en) * 2013-10-08 2015-04-15 Ystem S.r.l. Pharmaceutical compositions for the treatment of muscular disorders
CN105030571A (en) * 2015-08-20 2015-11-11 彭再辉 Pure physical sunscreen lotion and preparation method thereof
CN105326726A (en) * 2015-12-11 2016-02-17 邓天华 Bamboo juice toning lotion and preparation method thereof
CN114259448A (en) * 2022-02-08 2022-04-01 上海唐阳化妆品商贸有限公司 Moisturizing and moisturizing face cream with anti-aging effect
CN114557940A (en) * 2022-02-28 2022-05-31 珠海伊斯佳科技股份有限公司 Anti-pollution sunscreen composition, anti-pollution sunscreen skin care composition and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101204417A (en) * 2007-12-18 2008-06-25 中国林业科学研究院林产化学工业研究所 Method of extracting natural oxidationresistant active substanceoil from orange tree bark
CN101732228A (en) * 2010-02-01 2010-06-16 云南龙润茶业集团有限公司 Tea facial mask and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101204417A (en) * 2007-12-18 2008-06-25 中国林业科学研究院林产化学工业研究所 Method of extracting natural oxidationresistant active substanceoil from orange tree bark
CN101732228A (en) * 2010-02-01 2010-06-16 云南龙润茶业集团有限公司 Tea facial mask and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
《林产化学与工业》 20080215 汪咏梅等 余甘子树皮提取物抗氧化及清除自由基活性初步研究 , 第01期 *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102784075A (en) * 2012-08-22 2012-11-21 中国农业科学院茶叶研究所 Sunscreen containing catechuic acid acetylated derivative
CN103432014A (en) * 2013-08-24 2013-12-11 上海艳紫化工科技有限公司 Catechin skin cream
CN103432014B (en) * 2013-08-24 2015-07-29 上海艳紫化工科技有限公司 Catechin skin cream
EP2859896A1 (en) * 2013-10-08 2015-04-15 Ystem S.r.l. Pharmaceutical compositions for the treatment of muscular disorders
CN104398451A (en) * 2014-11-14 2015-03-11 成都鹏翔生物科技有限公司 Moisture-retaining skin-care emulsion containing chestnut extractive and preparation method thereof
CN104490681A (en) * 2014-12-10 2015-04-08 唯美度科技(北京)有限公司 Skin softening cream capable of forming multiple sun screens
CN105030571A (en) * 2015-08-20 2015-11-11 彭再辉 Pure physical sunscreen lotion and preparation method thereof
CN105030571B (en) * 2015-08-20 2018-08-10 彭再辉 A kind of pure physical sunscreen breast and preparation method thereof
CN105326726A (en) * 2015-12-11 2016-02-17 邓天华 Bamboo juice toning lotion and preparation method thereof
CN105326726B (en) * 2015-12-11 2019-01-29 邓天华 A kind of bamboo juice toner and preparation method thereof
CN114259448A (en) * 2022-02-08 2022-04-01 上海唐阳化妆品商贸有限公司 Moisturizing and moisturizing face cream with anti-aging effect
CN114557940A (en) * 2022-02-28 2022-05-31 珠海伊斯佳科技股份有限公司 Anti-pollution sunscreen composition, anti-pollution sunscreen skin care composition and preparation method thereof

Also Published As

Publication number Publication date
CN102228418B (en) 2013-03-20

Similar Documents

Publication Publication Date Title
CN102228418B (en) Cosmetic for keeping skin health and beauty and preparation method thereof
CN106580798B (en) A kind of all about eyes and preparation method
CN101125119B (en) Tibetan materia medica with whitening anti-senility function and application thereof
CN101590003B (en) Whitening spot-relieving cream cosmetic and preparation method thereof
CN105616283A (en) Plant-essence restorative facial cream
KR20170083068A (en) Skincare formulations and regimens
CN102525870A (en) Traditional Chinese medicine beauty mask
CN102293733A (en) Overall whitening and speckle removal skin care product
CN102091006A (en) Tea extract facial cleanser and preparation method thereof
CN108653136A (en) A kind of Chinese medicine composition and its mixed extract being used for cosmetics frost breast and facial mask
CN107213096A (en) A kind of plant type suncream and preparation method thereof
CN108186503A (en) A kind of whitening emulsion of the extract containing Magnolia binodii and preparation method thereof
Arora et al. Herbal active ingredients used in skin cosmetics
CN112043661B (en) Whitening aloe gel and preparation method thereof
CN104382784A (en) Facial mask emulsion and preparation method thereof
CN107007509A (en) One kind balance restorative facial cream
CN106727150A (en) A kind of sun-proof skin care cosmetic composition and its application
CN111000759A (en) Bergamot essential oil repair cream and preparation method thereof
CN102342903B (en) Skincare composition as well as use and method of same for preventing and delaying skin aging
CN106491513A (en) A kind of skin nutritious agent containing Sparassis crispa
CN106176451A (en) A kind of skin care item based on coffee uva plant extract and preparation method thereof
CN105534858A (en) Plant essence powder, facial mask cream and facial mask powder
CN101467946A (en) Repair powder for nursing face
CN112957304A (en) Plant composition for cosmetics, mixed extracting solution and preparation method
CN110664700B (en) Composition and application thereof in preparation of product for preventing and treating acne

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: LONGFA PHARMACY CO., LTD., YUNNAN

Free format text: FORMER OWNER: YUNNAN LONGRUN TEA GROUP CO., LTD.

Effective date: 20140221

COR Change of bibliographic data

Free format text: CORRECT: ADDRESS; FROM: 650106 KUNMING, YUNNAN PROVINCE TO: 675000 CHUXIONG YI AUTONOMOUS PREFECTURE, YUNNAN PROVINCE

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20140221

Address after: 675000 Lucheng South Road, Chuxiong, Chuxiong No. 384 South Road, No.

Patentee after: Longfa Pharmacy Co., Ltd., Yunnan

Address before: 650106 Yunnan Province, Kunming City Haiyuan Road No. 1299 longrun building

Patentee before: Yunnan Longrun Tea Group Co., Ltd.

CP01 Change in the name or title of a patent holder
CP01 Change in the name or title of a patent holder

Address after: 675000 Lucheng South Road, Chuxiong, Chuxiong No. 384 South Road, No.

Patentee after: Yunnan Longfa pharmaceutical Limited by Share Ltd

Address before: 675000 Lucheng South Road, Chuxiong, Chuxiong No. 384 South Road, No.

Patentee before: Longfa Pharmacy Co., Ltd., Yunnan