CN102212146B - 一种侧链用硫辛酸修饰的亲水性聚合物 - Google Patents
一种侧链用硫辛酸修饰的亲水性聚合物 Download PDFInfo
- Publication number
- CN102212146B CN102212146B CN 201110110986 CN201110110986A CN102212146B CN 102212146 B CN102212146 B CN 102212146B CN 201110110986 CN201110110986 CN 201110110986 CN 201110110986 A CN201110110986 A CN 201110110986A CN 102212146 B CN102212146 B CN 102212146B
- Authority
- CN
- China
- Prior art keywords
- polymer
- hydrophilic polymer
- thioctic acid
- crosslinked
- nanoparticle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Medicinal Preparation (AREA)
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 201110110986 CN102212146B (zh) | 2009-07-23 | 2009-07-23 | 一种侧链用硫辛酸修饰的亲水性聚合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 201110110986 CN102212146B (zh) | 2009-07-23 | 2009-07-23 | 一种侧链用硫辛酸修饰的亲水性聚合物 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009101819226A Division CN101665569B (zh) | 2009-07-23 | 2009-07-23 | 侧链用硫辛酸修饰的亲水性聚合物及其制备和应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102212146A CN102212146A (zh) | 2011-10-12 |
CN102212146B true CN102212146B (zh) | 2013-02-13 |
Family
ID=44743708
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 201110110986 Active CN102212146B (zh) | 2009-07-23 | 2009-07-23 | 一种侧链用硫辛酸修饰的亲水性聚合物 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102212146B (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104004001B (zh) * | 2014-05-28 | 2016-03-30 | 苏州大学 | 含双硫五元环功能基团的环状碳酸酯单体及其制备方法 |
CN104497171B (zh) * | 2015-01-07 | 2017-05-10 | 博瑞生物医药(苏州)股份有限公司 | 基于透明质酸的两亲聚合物、其制备方法与应用 |
CN108392471B (zh) * | 2018-03-01 | 2020-06-16 | 苏州大学张家港工业技术研究院 | 基于末端含硫辛酰基星型聚合物的纳米药物 |
CN109700779A (zh) * | 2018-09-14 | 2019-05-03 | 苏州科技大学 | 复合巯基改性壳聚糖的可降解聚合物微球 |
CN110387142B (zh) * | 2019-08-14 | 2021-08-17 | 桂林理工大学 | 一种负载有脂溶性色素的桃胶多糖纳米球的制备方法 |
CN113208113B (zh) * | 2021-05-08 | 2022-08-09 | 杭州诺莘科技有限责任公司 | 肉桂酸、硫辛酸共接枝壳聚糖修饰的nmn脂质体及其制备和应用 |
CN114790377B (zh) * | 2021-06-08 | 2023-06-16 | 天津大学 | 一种超支化的聚合物压敏胶及其制备方法和应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1377267A (zh) * | 1999-10-01 | 2002-10-30 | Skw特罗斯特贝格股份公司 | 包含α-硫辛酸(衍生物)的延时释放剂型 |
CN1688598A (zh) * | 2002-09-09 | 2005-10-26 | 独立行政法人科学技术振兴机构 | 链化合物和配体、及其制备方法 |
US20070281904A1 (en) * | 2006-06-02 | 2007-12-06 | Shenda Baker | Chitosan-derivative compounds and methods of controlling microbial populations |
WO2008106640A1 (en) * | 2007-03-01 | 2008-09-04 | Cedars-Sinai Medical Center | Antioxidant polymers containing [1,2]-dithiolane moieties and uses thereof |
WO2009080220A1 (en) * | 2007-12-21 | 2009-07-02 | Sigea S.R.L. | Polysaccharide derivatives of lipoic acid, their preparation, use as skin cosmetics and medical devices |
-
2009
- 2009-07-23 CN CN 201110110986 patent/CN102212146B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1377267A (zh) * | 1999-10-01 | 2002-10-30 | Skw特罗斯特贝格股份公司 | 包含α-硫辛酸(衍生物)的延时释放剂型 |
CN1688598A (zh) * | 2002-09-09 | 2005-10-26 | 独立行政法人科学技术振兴机构 | 链化合物和配体、及其制备方法 |
US20070281904A1 (en) * | 2006-06-02 | 2007-12-06 | Shenda Baker | Chitosan-derivative compounds and methods of controlling microbial populations |
WO2008106640A1 (en) * | 2007-03-01 | 2008-09-04 | Cedars-Sinai Medical Center | Antioxidant polymers containing [1,2]-dithiolane moieties and uses thereof |
WO2009080220A1 (en) * | 2007-12-21 | 2009-07-02 | Sigea S.R.L. | Polysaccharide derivatives of lipoic acid, their preparation, use as skin cosmetics and medical devices |
Non-Patent Citations (1)
Title |
---|
Stephanie Hornig et al.Synthesis and Characterization of Sulfur Containing Dextran- and β-Cyclodextrin Derivatives.《Polymer Bulletin》.2007,第59卷第65-71页. * |
Also Published As
Publication number | Publication date |
---|---|
CN102212146A (zh) | 2011-10-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101665569B (zh) | 侧链用硫辛酸修饰的亲水性聚合物及其制备和应用 | |
CN102212146B (zh) | 一种侧链用硫辛酸修饰的亲水性聚合物 | |
Li et al. | Redox-sensitive micelles self-assembled from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel | |
Jia et al. | Multi-functionalized hyaluronic acid nanogels crosslinked with carbon dots as dual receptor-mediated targeting tumor theranostics | |
CN106727307B (zh) | 一种还原敏感纳米胶束的制备及应用 | |
CN104497171B (zh) | 基于透明质酸的两亲聚合物、其制备方法与应用 | |
Luo et al. | Redox-sensitive micelles based on retinoic acid modified chitosan conjugate for intracellular drug delivery and smart drug release in cancer therapy | |
CN110237035B (zh) | 一种主动靶向型两亲性多肽纳米药物载体及其制备与应用 | |
CN105524272B (zh) | 硫辛酸修饰的聚乙二醇-聚氨基酸嵌段共聚物的制备和应用 | |
Han et al. | Redox-sensitive micelles for targeted intracellular delivery and combination chemotherapy of paclitaxel and all-trans-retinoid acid | |
Meng et al. | Synthesis and characterization of curcumin-loaded pH/reduction dual-responsive folic acid modified carboxymethyl cellulose-based microcapsules for targeted drug delivery | |
CN104262638A (zh) | 透明质酸-胱胺-聚乳酸-羟基乙酸接枝聚合物及其制备方法 | |
CN107149592A (zh) | 具有淋巴靶向功能的生物自组装纳米晶注射剂及制备方法 | |
Li et al. | Fabrication of a multi-level drug release platform with liposomes, chitooligosaccharides, phospholipids and injectable chitosan hydrogel to enhance anti-tumor effectiveness | |
CN105131182B (zh) | 普朗尼克‑聚(β‑氨基酯)聚合物及其合成和应用方法 | |
CN105524271A (zh) | 胆酸修饰的聚氨基酸嵌段共聚物的合成及应用 | |
Sadaquat et al. | Biodegradable and biocompatible polymeric nanoparticles for enhanced solubility and safe oral delivery of docetaxel: In vivo toxicity evaluation | |
CN105859990B (zh) | 侧链含硫辛酰基的聚合物、其制备方法及由其制备的聚合物囊泡及其应用 | |
CN111870579B (zh) | 一种肿瘤靶向纳米胶束、制备方法及作为药物载体的应用 | |
CN107308112A (zh) | 一种改性黄原胶纳米胶束的制备方法 | |
CN104667286B (zh) | 一种尺寸单分散性聚合物纳米囊泡及其制备方法和应用 | |
KR100831391B1 (ko) | pH 민감성 이미다졸 그룹을 함유한 키토산 복합체 및 그제조방법 | |
CN104398504B (zh) | 一种去氧鬼臼毒素类药物的药物组合物及其制备方法和制剂 | |
CN112156066B (zh) | 一种包含胶束的可注射复合水凝胶双载药系统的制备方法 | |
CN112656951B (zh) | 交联型酸响应天然多糖聚合物前药、制备方法及用途 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: BORUI BIO-MEDICINE TECHNOLOGY (SUZHOU) CO., LTD. Free format text: FORMER OWNER: SUZHOU UNIVERSITY Effective date: 20150601 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20150601 Address after: Xinghu Street Industrial Park of Suzhou city in Jiangsu province 215123 No. 218 BioBAY building C27 Patentee after: Borui Bio-medical Technology (Jiangsu) Co., Ltd. Address before: 215123 Suzhou City, Suzhou Province Industrial Park, No. love road, No. 199 Patentee before: Soochow University |
|
C56 | Change in the name or address of the patentee | ||
CP03 | Change of name, title or address |
Address after: Suzhou City, Jiangsu Province, Suzhou Industrial Park 215123 Xinghu Street No. 218 Nano Technology Park building C25 Patentee after: Borui Pharmaceutical (Suzhou) Limited by Share Ltd Address before: Xinghu Street Industrial Park of Suzhou city in Jiangsu province 215123 No. 218 BioBAY building C27 Patentee before: Borui Bio-medical Technology (Jiangsu) Co., Ltd. |
|
TR01 | Transfer of patent right |
Effective date of registration: 20201217 Address after: 22 Binjiang South Road, Taixing Economic Development Zone, Taizhou City, Jiangsu Province Patentee after: BRIGHTGENE BIO-MEDICAL TECHNOLOGY Co.,Ltd. Patentee after: Borui biomedical (Suzhou) Co.,Ltd. Address before: Building C25, nanotechnology Park, 218 Xinghu street, Suzhou Industrial Park, Jiangsu Province Patentee before: Borui biomedical (Suzhou) Co.,Ltd. |
|
TR01 | Transfer of patent right |