CN102204995B - Kidney-reinforcing tonic wine - Google Patents

Kidney-reinforcing tonic wine Download PDF

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CN102204995B
CN102204995B CN201110138602XA CN201110138602A CN102204995B CN 102204995 B CN102204995 B CN 102204995B CN 201110138602X A CN201110138602X A CN 201110138602XA CN 201110138602 A CN201110138602 A CN 201110138602A CN 102204995 B CN102204995 B CN 102204995B
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kidney
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CN102204995A (en
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于海先
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WEIHAI JINYIYANG PHARMACEUTICAL CO Ltd
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Abstract

The invention relates to a kidney-tonifying kidney-reinforcing traditional Chinese medicine health wine, a kidney-reinforcing tonic wine, which comprises the following herbs of 0.4-0.5 g of wapiti velvet antler, 25.0-30.0 g of ginseng, 14.0-15.0 g of mythic fungus, 20.0-22.0 g of epimedy, 4.0-5.0 g of poria cocos, and 25.0-30.0 g of wolfberry, and is prepared by soaking the herbs with 50-degree liquor for 720 hours, filtering, and blending the herb filtrate with sweet yellow rice wine and water. The invention has the efficacy of tonifying kidney and reinforcing kidney, nourishing yin and strengthening yang, boosting essence and nourishing blood, enhancing immunity, fatigue resistance, and aging resistance. Compared with traditional medicinal liquor, the kidney-reinforcing tonic wine has the advantages of strong efficacy, fast effect, high curative effect, and low cost, and has good exploitation and application prospects.

Description

A kind of kidney healthful tonic wine and preparation method thereof
Technical field
The present invention relates to have the Traditional Chinese medicinal health-care wine of invigrating kidney, specifically a kind of kidney healthful tonic wine and preparation method thereof.
Background technology
Along with the raising of expanding economy and people's living standard, people pay attention to the healthy and quality of life of oneself more." kidney " in theory of Chinese medical science is an important system of human body.It comprises kidney, the people's of urinary system the system such as reproduction, immunity, endocrine.Kidney is the ground of congenital essence storage, and is basic for life, dominates growth promoter.The symptoms such as shortness of breath and tired spirit, soreness of the waist and knees and senilism appear in kidney exhaustion.For addressing the above problem, building body, medical research staff just constantly develops various characteristic the kidney invigorating Chinese patent medicine or health promoting wine.
Summary of the invention
The purpose of this invention is to provide a kind of the kidney invigorating and essence nourishing that has, nourishing the liver to improve visual acuity, kidney invigorating and YANG supporting, invigorating the spleen to benefit the lung, the Fructus Alpiniae Oxyphyllae of calming the nerves, bone and muscle strengthening, the energy building body strengthens kidney healthful tonic wine of sexual function of human body and immunity and preparation method thereof.
Technical solution of the present invention: a kind of kidney healthful tonic wine, every Hydrargyri Oxydum Rubrum wine is made than raw material by following weight: cervus elaphus linnaeus 0.4-0.5 gram, Radix Ginseng 25.0-30.0 gram, Ganoderma 14.0-15.0 gram, Herba Epimedii 20.0-22.0 gram, Poria 4.0-5.0 gram, Fructus Lycii 25.0-30.0 gram, 50 ° of Chinese liquor 500 grams.
The preferred weight proportioning of every its raw material of Hydrargyri Oxydum Rubrum wine of kidney healthful tonic wine provided by the invention is: cervus elaphus linnaeus 0.48 gram, Radix Ginseng 28.80 grams, Ganoderma 14.40 grams, Herba Epimedii 21.60 grams, Poria 4.80 grams, Fructus Lycii 28.80 grams, 50 ° of Chinese liquor 500 grams.
The preparation method of kidney healthful tonic wine of the present invention is:
1, press the weight ratio of cervus elaphus linnaeus, Radix Ginseng, Ganoderma, Herba Epimedii, Poria, Fructus Lycii, the selected Chinese medicinal material that cooks is made raw material;
2, with six kinds of Chinese medicinal materials of 50 ° of soaking in Chinese liquor, soaked 720 hours;
3, the herb liquid with infusion filters, and removes the medical material slag;
4, blend with sweet yellow rice wine and water, transfer to drug filtrate 1000ml, standing 72 hours;
5, the medicinal liquid after blending filters, fill.
Technical scheme of the present invention is according to the nutrition of human body and healthy needs, has the effect of building body, extracts from the medical value of following natural materials.
Cervus elaphus linnaeus: invigorating kidney-YANG, benefiting essence-blood, bone and muscle strengthening.
Radix Ginseng: strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves, tonify deficiency righting.
Ganoderma: invigorating QI and tranquilization, relieving cough and asthma; Benefiting qi and nourishing blood, spleen-benefiting mind-tranquilizing.
Herba Epimedii: kidney invigorating and YANG supporting, bone and muscle strengthening, wind-damp dispelling.
Poria: eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.
Fructus Lycii: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.
The present invention adopts and multiple the useful material of human body is carried out reasonable preparation, with soaking in Chinese liquor, blends with sweet yellow rice wine or water and makes it to produce good synergism.Has invigrating kidney, YIN nourishing and YANG strengthening, enhancing immunity, resisting fatigue, anti-aging effect.
Usage of the present invention and consumption: oral, every day 50ml.
The specific embodiment
Embodiment 1: a kind of kidney healthful tonic wine, every Hydrargyri Oxydum Rubrum wine is to be made by the raw material of following weight proportioning: cervus elaphus linnaeus 0.48 gram, Radix Ginseng 28.80 grams, Ganoderma 14.40 grams, Herba Epimedii 21.60 grams, Poria 4.80 grams, Fructus Lycii 28.80 grams, 50 ° of Chinese liquor 500 grams.
Embodiment 2: a kind of kidney healthful tonic wine, every Hydrargyri Oxydum Rubrum wine is to be made by the raw material of following weight proportioning: cervus elaphus linnaeus 0.40 gram, Radix Ginseng 28.00 grams, Ganoderma 14.00 grams, Herba Epimedii 21.00 grams, Poria 4.00 grams, Fructus Lycii 28.00 grams, 50 ° of Chinese liquor 500 grams.
Embodiment 3: a kind of kidney healthful tonic wine, every Hydrargyri Oxydum Rubrum wine is to be made by the raw material of following weight proportioning: cervus elaphus linnaeus 0.50 gram, Radix Ginseng 29.00 grams, Ganoderma 15.00 grams, Herba Epimedii 22.00 grams, Poria 5.00 grams, Fructus Lycii 29.00 grams, 50 ° of Chinese liquor 500 grams.
Embodiment 4: a kind of kidney healthful tonic wine, every Hydrargyri Oxydum Rubrum wine is made than raw material by following weight: cervus elaphus linnaeus 0.45 gram, Radix Ginseng 28.50 grams, Ganoderma 14.50 grams, Herba Epimedii 21.50 grams, Poria 4.50 grams, Fructus Lycii 28.50 grams, 50 ° of Chinese liquor 500 grams.
Embodiment 5: a kind of kidney healthful tonic wine, every Hydrargyri Oxydum Rubrum wine is made than raw material by following weight: cervus elaphus linnaeus 0.4-0.5 gram, Radix Ginseng 25.0-30.0 gram, Ganoderma 14.0-15.0 gram, Herba Epimedii 20.0-22.0 gram, Poria 4.0-5.0 gram, Fructus Lycii 25.0-30.0 gram, 50 ° of Chinese liquor 500 grams.
The preparation method of kidney healthful tonic wine of the present invention:
1, the selected Chinese medicinal material raw material that cooks by weight ratio, the specification requirement of medicinal material processing is as follows:
Cervus elaphus linnaeus: burn remove floss, transection sheet flattens drying.
Radix Ginseng: run through shave, drying.
Ganoderma: remove impurity and wood flour, cleaning, drying or section.
Herba Epimedii: remove impurity, win blade, the spray clear water slightly moistens shredding, drying.
Poria: soak, clean, after profit, pin steams, and in time is cut into piece or cuts sheet, dries.
Fructus Lycii: put dry place, shady and cool place, anti-sultry, protection against the tide, mothproof.
2, with 50 ° of Chinese liquor 500 grams, soak above-mentioned six kinds of Chinese medicinal materials, soaked 720 hours;
3, the herb liquid after soaking filters, and removes the medical material slag;
4, blend with sweet yellow rice wine and water, transfer to drug filtrate 1000ml, standing 72 hours;
5, the medicinal liquid after blending filters, fill.
The present invention has the function of kidney invigorating and YANG supporting, beneficial intensive culture blood, compares with traditional medicated wine, and kidney healthful tonic wine has strong drug action, instant effect, curative effect is high and low cost and other advantages, has good development prospect.
Usage of the present invention and consumption: oral, every day 50ml.20 days each courses for the treatment of, totally three courses for the treatment of.
The clinical research cooperative groups verifies curative effect of the present invention and health-care effect, and specific embodiments is as follows:
1. experiment material
The experiment material therefor is the former side's substrate of kidney healthful tonic wine of the present invention, and with former substrate simmer down to 1:5 concentration, is stored in and preserves standby experiment use in 4 ° of C refrigerators.
2. experimental apparatus
The experiment instrument comprises that EB-6 type transfer rod, hydrocortisone radioimmunoassay medicine box, EJ-008 type factory immunity enumerator, Swiss are mice system, testosterone radioimmunoassay medicine box, FJ-2102 liquid scintillation counter.
3. method and the result of testing
(1) to the observation of animal acute toxicity effect
Healthy Swiss kind mice, body weight 20 ± 0.5 grams, male female half and half.Kidney healthful tonic wine substrate wine is concentrated into the concentration of 1:25, gives mouse stomach.The experiment first day early, respectively be administered once evening, is the 0.2ml/10g Mus heavy at every turn, and then Continuous Observation is 7 days.The experimental session mice is movable, appetite is all good, dorsal body setae gloss, and expression and urine are without extremely, and abnormal phenomena does not also appear in 40 none death of mice used.Do not see the Acute Toxicity of kidney healthful tonic wine in this experiment, calculate its median lethal dose(LD 50) (LD50) therefore can't ask, the maximum tolerance that only can roughly calculate its oral administration is the concentration>40ml/kg body weight of 1:25.The dose of this experiment is more than 1600 times of quantity, illustrates that kidney healthful tonic wine is without obvious Acute Toxicity.
(2) on the impact of normal the weight of animals
Healthy male Swiss kind mice about body weight 20g, is divided into two groups at random by the body weight equilibrium.Give respectively kidney healthful tonic wine and normal saline 0.2ml/10g Mus heavy gavage, once a day, continuous 7 days.Record respectively body weight before and after administration, with the relatively variation of body weight between two groups of T check, result shows, this wine on normal the weight of animals without impact.
(3) on the impact of animal movement muscle power
20 of healthy Swiss kind mices about body weight 20 grams, by the balanced random packet of body weight, give respectively the heavy gavage of normal saline and kidney healthful tonic wine 0.2ml/10g Mus, once a day, and continuous 10 days.Tested the 11 day, and regulated the EB-6 transfer rod, make its rotating speed be 12 circles/minute, animal is placed on rod one by one, begin to record the time of staying of animal on rod to be time of animal movement physical demands, also bearing the time for animal muscle power.Compare group difference with the T method of inspection.Result demonstration, kidney healthful tonic wine have raising animal movement muscle power and motion tolerates physical effect.
(4) on the impact of animal testis, epididymis tissue weight
28 of healthy male Swiss kind mices, about body weight 20 grams, be divided at random two groups by the body weight equilibrium, give respectively normal saline and kidney healthful tonic wine 0.2ml/10g, the heavy gavage of Mus, once a day, continuous 10 days, tested the 11 day, animal is taken off cervical vertebra puts to death, win testis, the epididymis tissue is placed in Bownis liquid and fixes 24 hours, carefully remove the accompanying fat of tissue, inhale in surface liquid with filter paper, ten thousand/ balance on weigh, and conversion is that testis or epididymis tissue wet/10 Mus are heavy, this drinking utensils of presentation of results has androgen-like action, impel the growth of gonophore.
(5) on the impact of sperm count in animal epididymis tissue
20 of healthy male Swiss kind mices about body weight 20 grams, are divided into two groups at random.Give respectively normal saline and kidney healthful tonic wine gavage, once a day, each 0.2ml/10 Mus is heavy, continuous 10 days, administration the 11 day was taken off cervical vertebra with animal and is put to death, win rapidly the epididymis tissue, after torsion balance is weighed, be placed in mortar and grind, with 15 times of ringer solution dilutions, at microscopically counting sperm number, and observe its activity situation, the sperm count conversion is ten thousand/10mg epididymis tissue, compare group difference with the T method of inspection, this drinking utensils of presentation of results has the effect that impels spermatogenesis.Counting is also observed simultaneously, and administration group sperm survival rate is 84% left and right, and the saline group is 66%, shows that kidney healthful tonic wine has the effect that improves motility of sperm and survival rate.
(6) to the yang deficiency the weight of animals, the impact of plasma cortisol, adrenal gland's weight.
74 of healthy male Swiss kind mices, about body weight 24 grams, 0.5% hydrocortisone 0.2ml/ of subcutaneous injection/day, continuous 7 days.See that around here the weight of animals obviously alleviates, average 21 about grams, (self cross-reference see notable difference P<0.01), and 30% the animal dead of having an appointment, surviving animals all visible hair is loose, fear of cold, limbs are sent out cool, and inappetence is dispirited.Tested the 8th day, animal is divided into two groups by the body weight Stochastic Equilibrium, give respectively normal saline and kidney healthful tonic wine 0.2ml/10g heavy gavage, once a day, continuous 12 days, experimental session recorded body weight once, and recorded result in every 4 days.Tested the 21st day, and extractd eyeball of mouse, by the socket of the eye venous blood sampling, anticoagulant heparin, centrifugal after, quantitatively draw blood plasma, by northern immunoreagent institute method, utilize EJ-2008r immunity enumerator, carry out plasma cortisol and measure.Compare group difference with the T method of inspection.Getting blood weighs simultaneously, and win bilateral adrenal glands, put in Bownis liquid and fix 24 hours, then blot surface liquid with filter paper, carefully go out its hetero-organizations such as degrease, weighing weight in wet base on ten thousand/balance, and conversion is heavy for adrenal gland's milligram weight in wet base/10 Mus, carries out statistical disposition by the method for inspection.On blood plasma cortisol and point out this wine not only to have on the impact of adrenal gland's weight to correct " yang deficiency " the weight of animals and the low effect of adrenal gland's endocrine function, and the effect that also has promotion " yang deficiency " animal adrenal gland to increase weight.
4. discuss
Kidney healthful tonic wine is by cervus elaphus linnaeus, Radix Ginseng, Ganoderma, Herba Epimedii, Poria, Fructus Lycii, through 50 ° of Chinese liquor lixiviates, formulated.Its chief component medicine all has the effect of warming the kidney to invigorate YANG.Through clinical observation, the description of test kidney healthful tonic wine has the effect of good the kidney invigorating, tonifying YANG, building body.Experiment is found the growth of testis tissue is had no significant effect, and illustrates that kidney healthful tonic wine is at gonad and the position below gonad on the impact of gonad gland axle.Kidney healthful tonic wine is except having sexual function certain regulating action, to the hypophysis of " yang deficiency " animal---and adrenal gland's endocrine axis hypofunction also has good role of correcting.The adrenal cortex function of " yang deficiency " animal is recovered, increase its plasma cortisol, its body of gland weight is increased.And has the effect that quickening " yang deficiency " the weight of animals recovers.Except this, kidney healthful tonic wine also has the effect of good increase campaign muscle power.Find kidney healthful tonic wine in experiment without the overt toxicity effect, illustrate that kidney healthful tonic wine is that a kind of curative effect is reliable, the health body-building good merchantable brand of application safety.

Claims (2)

1. kidney healthful tonic wine is characterized in that every Hydrargyri Oxydum Rubrum wine made than raw material by following weight: cervus elaphus linnaeus 0.4-0.5 gram, Radix Ginseng 25.0-30.0 gram, Ganoderma 14.0-15.0 gram, Herba Epimedii 20.0-22.0 gram, Poria 4.0-5.0 gram, Fructus Lycii 25.0-30.0 gram, 50 ° of Chinese liquor 500 grams.
2. a kind of kidney healthful tonic wine according to claim 1 is characterized in that every Hydrargyri Oxydum Rubrum wine made than raw material by following weight: cervus elaphus linnaeus 0.48 gram, Radix Ginseng 28.80 grams, Ganoderma 14.40 grams, Herba Epimedii 21.60 grams, Poria 4.80 grams, Fructus Lycii 28.80 grams, 50 ° of Chinese liquor 500 grams.
3. the preparation method of kidney healthful tonic wine according to claim 1 and 2 is characterized in that comprising the following steps:
1, press the weight ratio of cervus elaphus linnaeus, Radix Ginseng, Ganoderma, Herba Epimedii, Poria, Fructus Lycii, the selected Chinese medicinal material that cooks is made raw material;
2, with six kinds of Chinese medicinal materials of 50 ° of soaking in Chinese liquor, soaked 720 hours;
3, the herb liquid with infusion filters, and removes the medical material slag;
4, blend with sweet yellow rice wine and water, transfer to drug filtrate 1000ml, standing 72 hours;
5, the medicinal liquid after blending filters, fill.
CN201110138602XA 2011-05-26 2011-05-26 Kidney-reinforcing tonic wine Active CN102204995B (en)

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CN102433249B (en) * 2011-12-08 2013-11-06 安徽华佗国药保健酒业有限公司 Medicinal health-care liquor for resisting fatigue and improving immunity and preparation method thereof
CN103897968B (en) * 2012-12-29 2016-01-20 吉林大清鹿苑保健科技有限公司 Pilose antler ginseng health-care wine of a kind of alleviating fatigue and preparation method thereof
CN103361230A (en) * 2013-07-02 2013-10-23 袁娟 Yin nourishing and kidney tonifying edible medicinal liquor and preparation method thereof
CN103361234A (en) * 2013-07-30 2013-10-23 孟宗科 Making method of healthcare Mythic Fungus spirit
CN105456640A (en) * 2014-09-28 2016-04-06 于宝庆 Traditional Chinese medicine composition for strengthening human body
CN104694358B (en) * 2015-03-20 2017-03-22 吉林大学 Cornu cervi healthcare wine for boosting immunity and preparation method thereof
CN104783256A (en) * 2015-04-13 2015-07-22 武清泉 Purple sweet potato and fructus lycii juice with eyesight improvement and kidney tonification functions
CN104893922A (en) * 2015-05-27 2015-09-09 蒋雪冬 Kidney-tonifying wine
CN107095971A (en) * 2016-02-19 2017-08-29 刘荣惠 A kind of formula of return of spring sweet dew tonic wine and preparation method thereof
CN109370856A (en) * 2018-12-24 2019-02-22 济南如画生物科技有限公司 A kind of health tonic wine and preparation method thereof
CN110368435A (en) * 2019-08-07 2019-10-25 韩体亮 A kind of kidney-tonifying and yang-strengthening medicinal liquor and preparation method thereof
CN112294895A (en) * 2020-08-24 2021-02-02 福州弘海生物科技有限公司 Male delayed spray and preparation method thereof
CN115700276A (en) * 2022-11-25 2023-02-07 广西农科环保科技有限公司 Formula and preparation method of black soldier fly and ginseng nutritional wine

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CN101019989A (en) * 2007-03-06 2007-08-22 王二丰 Kidney invigorating and Yang strengthening Chinese medicine prepn

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CN101019989A (en) * 2007-03-06 2007-08-22 王二丰 Kidney invigorating and Yang strengthening Chinese medicine prepn

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