CN102186521B - 具有用于自动重构的剂量旋钮致动机构的医用注射器 - Google Patents

具有用于自动重构的剂量旋钮致动机构的医用注射器 Download PDF

Info

Publication number
CN102186521B
CN102186521B CN2009801415131A CN200980141513A CN102186521B CN 102186521 B CN102186521 B CN 102186521B CN 2009801415131 A CN2009801415131 A CN 2009801415131A CN 200980141513 A CN200980141513 A CN 200980141513A CN 102186521 B CN102186521 B CN 102186521B
Authority
CN
China
Prior art keywords
sleeve
knob
plunger
stem
channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN2009801415131A
Other languages
English (en)
Chinese (zh)
Other versions
CN102186521A (zh
Inventor
A·费亚
R·A·克罗嫩贝格
L·韦德林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of CN102186521A publication Critical patent/CN102186521A/zh
Application granted granted Critical
Publication of CN102186521B publication Critical patent/CN102186521B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN2009801415131A 2008-09-18 2009-09-18 具有用于自动重构的剂量旋钮致动机构的医用注射器 Active CN102186521B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19246608P 2008-09-18 2008-09-18
US61/192,466 2008-09-18
PCT/US2009/057439 WO2010033778A2 (en) 2008-09-18 2009-09-18 Medical injector with dose knob activation for automated reconstitution

Publications (2)

Publication Number Publication Date
CN102186521A CN102186521A (zh) 2011-09-14
CN102186521B true CN102186521B (zh) 2013-07-24

Family

ID=42040150

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801415131A Active CN102186521B (zh) 2008-09-18 2009-09-18 具有用于自动重构的剂量旋钮致动机构的医用注射器

Country Status (7)

Country Link
US (1) US8403883B2 (enExample)
EP (1) EP2328639B1 (enExample)
JP (1) JP5379233B2 (enExample)
CN (1) CN102186521B (enExample)
DK (1) DK2328639T3 (enExample)
ES (1) ES2625488T3 (enExample)
WO (1) WO2010033778A2 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2326367B1 (en) * 2008-07-04 2018-11-14 SHL Group AB Medicament delivery device with mixing mechanism
ES2766253T3 (es) 2008-09-18 2020-06-12 Becton Dickinson Co Inyector médico con émbolo con función de trinquete
WO2010033790A2 (en) * 2008-09-18 2010-03-25 Becton, Dickinson And Company Medical injector with rotatable body portions
WO2011003820A1 (de) * 2009-07-06 2011-01-13 Sanofi-Aventis Deutschland Gmbh Hitze- und schüttelstabile insulinzubereitungen
EP2493529B1 (en) * 2009-10-26 2016-03-30 SHL Group AB Medicament delivery device
ES2784853T3 (es) 2009-12-04 2020-10-01 Becton Dickinson And Company Inc Cartucho para contener y dispensar un medicamento
WO2011101379A1 (en) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2399635A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
GB201012179D0 (en) * 2010-07-20 2010-09-01 Future Injection Technologies Injection device
EP2468333A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
USRE48593E1 (en) 2010-12-21 2021-06-15 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2468330A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489389A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Detent mechanism
EP2489385A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
CN105498049B (zh) * 2011-03-17 2018-09-21 贝克顿·迪金森公司 具有棘轮式柱塞的医用注入器
CA2745320A1 (en) * 2011-07-06 2013-01-06 Duoject Medical Systems Inc. Reconstitution device
US20130085452A1 (en) 2011-09-30 2013-04-04 Becton Dickinson France, S.A.S. Syringe Assembly Having a Rotatably Advanceable Plunger Rod
EP2788047A1 (en) * 2011-12-06 2014-10-15 Novo Nordisk A/S A drive mechanism for an injection device and a method of assembling an injection device incorporating such drive mechanism
EP2606924A1 (en) 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector having a retracting syringe carrier
US9751056B2 (en) 2012-01-23 2017-09-05 Merit Medical Systems, Inc. Mixing syringe
US8834449B2 (en) 2012-01-23 2014-09-16 Ikomed Technologies, Inc. Mixing syringe
US9095394B2 (en) * 2012-04-26 2015-08-04 Kyphon Sarl Cement delivering device and method
EP2823841A1 (en) * 2013-07-09 2015-01-14 Sanofi-Aventis Deutschland GmbH Autoinjector
US11129939B2 (en) 2013-11-15 2021-09-28 Shl Medical Ag Medicament delivery device
EP2923714A1 (en) 2014-03-28 2015-09-30 Sanofi-Aventis Deutschland GmbH Autoinjector triggered by skin contact
US20150290078A1 (en) * 2014-04-14 2015-10-15 Massachusetts Institute Of Technology Reconstitution of pharmaceuticals for injection
GB2529621B (en) * 2014-08-21 2016-12-07 Owen Mumford Ltd Safety syringe
US10143625B2 (en) 2015-03-17 2018-12-04 Recon Therapeutics, Inc. Pharmaceutical reconstitution
TW201707738A (zh) 2015-06-03 2017-03-01 賽諾菲阿凡提斯德意志有限公司 注射器支架及自動注射器（二）
RU2738018C2 (ru) 2016-04-15 2020-12-07 Сантен Фармасьютикал Ко., Лтд. Точный, прецизионный микролитровый дозирующий шприц
JP7098171B2 (ja) * 2017-06-16 2022-07-11 クリーデンス メドシステムズ，インコーポレイテッド 安全シリンジのシステムおよび方法
EP3593838A1 (en) * 2018-07-13 2020-01-15 Zyno Medical, Llc High precision syringe with removable pump unit
CA3119455C (en) 2018-11-13 2024-07-02 Credence Medsystems, Inc. MULTI-SITE INJECTION SYSTEM AND METHOD
EP4058108A2 (en) * 2019-11-14 2022-09-21 Congruence Medical Solutions, LLC Variable dosing syringe
WO2021257911A1 (en) 2020-06-17 2021-12-23 Credence Medsystems, Inc. System and method for microdose injection

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6270479B1 (en) * 1998-10-26 2001-08-07 Pharmacia Ab Autoinjector
US20050277885A1 (en) * 2002-11-25 2005-12-15 Benjamin Scherer Auto-injector comprising a resettable releasing safety device
US20060184117A1 (en) * 2005-01-18 2006-08-17 Barry Knight Pen shaped medication injection devices
US20060270985A1 (en) * 2003-11-05 2006-11-30 Edgar Hommann Device for administering an injectable product

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
IL86799A (en) 1987-07-02 1993-03-15 Kabi Pharmacia Ab Method and device for injection
GB9223183D0 (en) * 1992-11-05 1992-12-16 Medimech Int Ltd Improvements related to auto injectors
DE19821934C1 (de) * 1998-05-15 1999-11-11 Disetronic Licensing Ag Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
ES2251371T3 (es) * 1999-04-16 2006-05-01 Becton Dickinson And Company Inyector de tipo pluma con caracteristicas de combinacion de sustancias automatizada.
WO2006058061A1 (en) * 2004-11-24 2006-06-01 Becton Dickinson And Company Automatic reconstitution injector device
US7407494B2 (en) * 2005-01-31 2008-08-05 Bostroem Anders Device for delivering medicament
JP4150389B2 (ja) * 2005-09-05 2008-09-17 日本ケミカルリサーチ株式会社 注射装置
JP4367653B2 (ja) * 2006-05-23 2009-11-18 前田産業株式会社 プレフィルドシリンジ用ホルダー及び注射器
ES2345694T3 (es) * 2007-01-17 2010-09-29 Shl Group Ab Dispositivo para administrar medicanto.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6270479B1 (en) * 1998-10-26 2001-08-07 Pharmacia Ab Autoinjector
US20050277885A1 (en) * 2002-11-25 2005-12-15 Benjamin Scherer Auto-injector comprising a resettable releasing safety device
US20060270985A1 (en) * 2003-11-05 2006-11-30 Edgar Hommann Device for administering an injectable product
US20060184117A1 (en) * 2005-01-18 2006-08-17 Barry Knight Pen shaped medication injection devices

Also Published As

Publication number Publication date
CN102186521A (zh) 2011-09-14
ES2625488T3 (es) 2017-07-19
EP2328639B1 (en) 2017-02-15
DK2328639T3 (en) 2017-05-22
US8403883B2 (en) 2013-03-26
EP2328639A2 (en) 2011-06-08
JP5379233B2 (ja) 2013-12-25
EP2328639A4 (en) 2015-01-21
WO2010033778A2 (en) 2010-03-25
WO2010033778A3 (en) 2010-07-01
US20120041366A1 (en) 2012-02-16
JP2012502757A (ja) 2012-02-02

Similar Documents

Publication Publication Date Title
CN102186521B (zh) 具有用于自动重构的剂量旋钮致动机构的医用注射器
CN102186518B (zh) 具有联接的主体部分的医用注射器
CN102186519B (zh) 具有按钮致动功能的医用注射器
CN102202710B (zh) 具有可旋转主体部的医用注射器
US8556862B2 (en) Needle mounting feature for ensuring proper reconstitution sequence
CN102196834B (zh) 具有可滑动套筒致动机构的医用注射器
CN101479003B (zh) 注射装置
CN103282067B (zh) 药物输送设备
US9199039B2 (en) Pusher with a coupling element
KR20160039207A (ko) 주사 가능 물질의 순차 주입용 주사기
CN102186520B (zh) 具有自动重构后剂量设置和自动柱塞驱动的医用注射装置
AU2007207309A1 (en) Injection device with secured dosing button
JP2012502757A5 (enExample)
CN102112166A (zh) 药物输送设备
US9061107B2 (en) Needle mounting feature for ensuring proper reconstitution sequence

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant