CN102178962A - Medical disinfection/sterilization ultrasound couplant and preparation method thereof - Google Patents
Medical disinfection/sterilization ultrasound couplant and preparation method thereof Download PDFInfo
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- CN102178962A CN102178962A CN 201110091453 CN201110091453A CN102178962A CN 102178962 A CN102178962 A CN 102178962A CN 201110091453 CN201110091453 CN 201110091453 CN 201110091453 A CN201110091453 A CN 201110091453A CN 102178962 A CN102178962 A CN 102178962A
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Abstract
The invention belongs to the technical field of a medical ultrasound couplant, and particularly relates to a medical disinfection/sterilization ultrasound couplant and a preparation method thereof. The technical scheme of the invention is as follows: the medical disinfection/sterilization ultrasound couplant is prepared from the following raw materials in percentage by weight: 0.2-0.8% of Carbomer 940, 3-9% of glycerol, 2-10% of ethanol, 0.05-0.4% of ethylparaben, 0.01-0.04% of DPP-300, 0.02-0.06% of chitosan, 0.2-1% of sodium hydroxide and the balance of distilled water. The medical disinfection/sterilization ultrasound couplant provided by the invention has a function of fast sterilization, and the ethylparaben, DPP and chitosan are sterilization bacteriostats. In the invention, the proportion has the functions of saving cost and improving sterilization effect; and the disinfection/sterilization ultrasound couplant causes no stimulus on the skin, further achieves the function of ultrasound disinfection/sterilization and can isolate the air between an ultrasound probe and the skin of a human body, thereby realizing zero decrement in the conduction process of sound waves and acquiring a reliable detection result.
Description
Technical field
The invention belongs to the medical ultrasonic coupling agent technical field, relate in particular to a kind of medical disinfecting sterilization ultrasonic coupling agent and preparation method thereof.
Background technology
Medical ultrasonic coupling agent is human body used gel preparation when doing ultrasonic examination, its purpose is to eliminate ultrasonic probe and human body and is examined air between the skin of position, strengthen the coupling between ultrasonic probe and the human body skin, make sound wave conduction not be subjected to air influence and decay, obtaining reliable result, for doctor's correct diagnosis provides foundation.And the most products of present widely used medical ultrasonic coupling agent are to handle through sterilization, realize asepticize, but the environment of coupling agent for medical use to using uses object not have the effect of disinfection.Because sound head is frequent to be contacted with detections different patients or therapentic part, is easy to generate cross infection, particularly for tract mucosa ultrasound detection or treatment; Cross infection during for fear of tract mucosa ultrasound detection, at present often adopt probe to be coated with ultrasonic coupling agent reuse condom to entangle probe and detect, this method is very loaded down with trivial details, cost strengthens, and the method that condom entangles probe has bigger influence to sound wave conduction and image definition, and therefore developing a kind of ultrasonic coupling agent that can disinfection has very important meaning.
Summary of the invention
The objective of the invention is to overcome above-mentioned technical defective, a kind of medical ultrasonic coupling agent that can disinfection and preparation method thereof is provided.
Technical scheme of the present invention is: a kind of medical disinfecting sterilization ultrasonic coupling agent is prepared from by following raw materials by weight percent:
Medical disinfecting sterilization ultrasonic coupling agent preferably is prepared from by following raw materials by weight percent:
Medical disinfecting sterilization ultrasonic coupling agent preferably is prepared from by following raw materials by weight percent:
Medical disinfecting sterilization ultrasonic coupling agent preferably is prepared from by following raw materials by weight percent:
The preparation method of medical disinfecting sterilization ultrasonic coupling agent is characterized in that:
(1) takes by weighing carbomer by above-mentioned prescription and be dissolved in swelling 24h-48h in an amount of distilled water, as A liquid;
(2) comply with above-mentioned prescription successively with glycerol, ethyl hydroxybenzoate, DPP and chitosan, ethanol, sodium hydroxide are dissolved in the distilled water, as B liquid;
(3) slowly pour B liquid into A liquid, slowly stir, A liquid becomes transparent gel-form by shallow milky, and adding distil water stirs to capacity again, and PH is 6-8.
Wherein, in the technical solution of the present invention, glycerol is wetting agent, and ethyl hydroxybenzoate, DPP and chitosan are as antibacterial and antibacterial, and ethanol is as solvent and antiseptic, and sodium hydroxide is as the PH regulator.
Beneficial effect of the present invention: medical disinfecting sterilization ultrasonic coupling agent of the present invention has the function of quick sterilization, and ethyl hydroxybenzoate, DPP and chitosan are sterilization bacteriostat.Adopt the proportioning described in the present invention, has the saving cost, improve the effect of biocidal efficacies, and this sterilization ultrasound coupling agent is to the effect of skin nonirritant, more can play the germ-resistant function of ultrasonic disinfection, air between isolated ultrasonic probe and the human body skin makes sound wave conduct undamped influence, can obtain reliable result.
The specific embodiment
Further specify technical scheme of the present invention below by specific embodiment, but technical scheme of the present invention is not exceeded with embodiment.
Embodiment 1
Medical disinfecting sterilization ultrasonic coupling agent preferably is prepared from by following raw materials by weight percent:
The preparation method of medical disinfecting sterilization ultrasonic coupling agent is characterized in that:
(1) takes by weighing carbomer by above-mentioned prescription and be dissolved in swelling 24h in an amount of distilled water, as A liquid;
(2) comply with above-mentioned prescription successively with glycerol, ethyl hydroxybenzoate, DPP and chitosan, ethanol, sodium hydroxide are dissolved in the distilled water, as B liquid;
(3) slowly pour B liquid into A liquid, slowly stir, A liquid becomes transparent gel-form by shallow milky, and adding distil water stirs to capacity again, and PH is 6.
Embodiment 2
Medical disinfecting sterilization ultrasonic coupling agent preferably is prepared from by following raw materials by weight percent:
The preparation method of medical disinfecting sterilization ultrasonic coupling agent is characterized in that:
(1) takes by weighing carbomer by above-mentioned prescription and be dissolved in swelling 30h in an amount of distilled water, as A liquid;
(2) comply with above-mentioned prescription successively with glycerol, ethyl hydroxybenzoate, DPP and chitosan, ethanol, sodium hydroxide are dissolved in the distilled water, as B liquid;
(3) slowly pour B liquid into A liquid, slowly stir, A liquid becomes transparent gel-form by shallow milky, and adding distil water stirs to capacity again, and PH is 7.
Embodiment 3
Medical disinfecting sterilization ultrasonic coupling agent preferably is prepared from by following raw materials by weight percent:
The preparation method of medical disinfecting sterilization ultrasonic coupling agent is characterized in that:
(1) takes by weighing carbomer by above-mentioned prescription and be dissolved in swelling 48h in an amount of distilled water, as A liquid;
(2) comply with above-mentioned prescription successively with glycerol, ethyl hydroxybenzoate, DPP and chitosan, ethanol, sodium hydroxide are dissolved in the distilled water, as B liquid;
(3) slowly pour B liquid into A liquid, slowly stir, A liquid becomes transparent gel-form by shallow milky, and adding distil water stirs to capacity again, and PH is 8.
Claims (5)
1. medical disinfecting sterilization ultrasonic coupling agent is characterized in that: be prepared from by following raw materials by weight percent:
2. medical disinfecting sterilization ultrasonic coupling agent as claimed in claim 1 is characterized in that: be prepared from by following raw materials by weight percent:
3. medical disinfecting sterilization ultrasonic coupling agent as claimed in claim 1 is characterized in that: be prepared from by following raw materials by weight percent:
4. medical disinfecting sterilization ultrasonic coupling agent as claimed in claim 1 is characterized in that: be prepared from by following raw materials by weight percent:
5. the preparation method of the described medical disinfecting of claim 1 sterilization ultrasonic coupling agent is characterized in that:
(1) takes by weighing carbomer by above-mentioned prescription and be dissolved in swelling 24h-48h in an amount of distilled water, as A liquid;
(2) comply with above-mentioned prescription successively with glycerol, ethyl hydroxybenzoate, DPP and chitosan, ethanol, sodium hydroxide are dissolved in the distilled water, as B liquid;
(3) slowly pour B liquid into A liquid, slowly stir, A liquid becomes transparent gel-form by shallow milky, and adding distil water stirs to capacity again, and PH is 6-8.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2011100914536A CN102178962B (en) | 2011-04-13 | 2011-04-13 | Medical disinfection/sterilization ultrasound couplant and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011100914536A CN102178962B (en) | 2011-04-13 | 2011-04-13 | Medical disinfection/sterilization ultrasound couplant and preparation method thereof |
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| CN102178962A true CN102178962A (en) | 2011-09-14 |
| CN102178962B CN102178962B (en) | 2012-08-08 |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102430131A (en) * | 2011-12-06 | 2012-05-02 | 董莉霞 | Antibacterial medical ultrasound compounding agent and preparation method thereof |
| CN102580124A (en) * | 2012-03-16 | 2012-07-18 | 广东工业大学 | Medical disinfecting ultrasound gel composition and preparation method |
| CN104888237A (en) * | 2015-06-26 | 2015-09-09 | 长春呈实健康实业有限公司 | Medical sterilization ultrasound coupling agent and preparation method thereof |
| CN105327369A (en) * | 2015-10-26 | 2016-02-17 | 佛山市平创医疗器械科技有限公司 | Sterilizing-and-disinfecting-type coupling agent and preparing method thereof |
| CN106075481A (en) * | 2016-07-06 | 2016-11-09 | 安徽智博新材料科技有限公司 | A kind of low viscosity medical ultrasonic coupling agent |
| CN106075480A (en) * | 2016-07-06 | 2016-11-09 | 安徽智博新材料科技有限公司 | A kind of medical ultrasonic coupling agent of self-cleaning sustainable use |
| CN107158273A (en) * | 2017-06-08 | 2017-09-15 | 苏州凌科特新材料有限公司 | Medical disinfection gel and preparation method thereof |
| CN110694081A (en) * | 2019-10-23 | 2020-01-17 | 南通大学 | Preparation method of temperature-sensitive self-curing bacteriostatic medical ultrasonic coupling agent |
| CN112147142A (en) * | 2020-09-23 | 2020-12-29 | 中国航发贵州黎阳航空动力有限公司 | Detection method for improving part contrast by using detection liquid and preparation method of detection liquid |
| CN112156382A (en) * | 2020-10-13 | 2021-01-01 | 青州市中医院 | Ultrasonic physiotherapy device for muscular dystrophy nursing based on oscillation circuit device |
| CN117427188A (en) * | 2023-12-07 | 2024-01-23 | 山东源科生物科技股份有限公司 | Non-irritating antibacterial ultrasonic coupling agent |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695576A (en) * | 2009-10-21 | 2010-04-21 | 新余市博源生化医用品有限责任公司 | Medical ultrasonic sterilization couplant |
-
2011
- 2011-04-13 CN CN2011100914536A patent/CN102178962B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695576A (en) * | 2009-10-21 | 2010-04-21 | 新余市博源生化医用品有限责任公司 | Medical ultrasonic sterilization couplant |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102430131A (en) * | 2011-12-06 | 2012-05-02 | 董莉霞 | Antibacterial medical ultrasound compounding agent and preparation method thereof |
| CN102580124A (en) * | 2012-03-16 | 2012-07-18 | 广东工业大学 | Medical disinfecting ultrasound gel composition and preparation method |
| CN102580124B (en) * | 2012-03-16 | 2013-06-26 | 广东工业大学 | Medical disinfecting ultrasound gel composition and preparation method |
| CN104888237A (en) * | 2015-06-26 | 2015-09-09 | 长春呈实健康实业有限公司 | Medical sterilization ultrasound coupling agent and preparation method thereof |
| CN105327369A (en) * | 2015-10-26 | 2016-02-17 | 佛山市平创医疗器械科技有限公司 | Sterilizing-and-disinfecting-type coupling agent and preparing method thereof |
| CN106075480A (en) * | 2016-07-06 | 2016-11-09 | 安徽智博新材料科技有限公司 | A kind of medical ultrasonic coupling agent of self-cleaning sustainable use |
| CN106075481A (en) * | 2016-07-06 | 2016-11-09 | 安徽智博新材料科技有限公司 | A kind of low viscosity medical ultrasonic coupling agent |
| CN107158273A (en) * | 2017-06-08 | 2017-09-15 | 苏州凌科特新材料有限公司 | Medical disinfection gel and preparation method thereof |
| CN110694081A (en) * | 2019-10-23 | 2020-01-17 | 南通大学 | Preparation method of temperature-sensitive self-curing bacteriostatic medical ultrasonic coupling agent |
| CN112147142A (en) * | 2020-09-23 | 2020-12-29 | 中国航发贵州黎阳航空动力有限公司 | Detection method for improving part contrast by using detection liquid and preparation method of detection liquid |
| CN112147142B (en) * | 2020-09-23 | 2023-10-27 | 中国航发贵州黎阳航空动力有限公司 | Detection method for improving part lining degree by using detection liquid and detection liquid preparation method |
| CN112156382A (en) * | 2020-10-13 | 2021-01-01 | 青州市中医院 | Ultrasonic physiotherapy device for muscular dystrophy nursing based on oscillation circuit device |
| CN117427188A (en) * | 2023-12-07 | 2024-01-23 | 山东源科生物科技股份有限公司 | Non-irritating antibacterial ultrasonic coupling agent |
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| Publication number | Publication date |
|---|---|
| CN102178962B (en) | 2012-08-08 |
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Address after: 277020 no.3168, Fuyuan Third Road, high tech Zone, Zaozhuang City, Shandong Province Patentee after: Shandong Yuanke Biotechnology Co., Ltd Address before: Yuejin Road Economic Development Zone, Shandong province 277300 Zaozhuang City Yicheng District No. 7 Patentee before: ZAOZHUANG HUIKANG MEDICAL SUPPLIES Co.,Ltd. |
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