CN102170898A - 用于辐射暴露治疗的组合物和方法 - Google Patents

用于辐射暴露治疗的组合物和方法 Download PDF

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Publication number
CN102170898A
CN102170898A CN2009801387748A CN200980138774A CN102170898A CN 102170898 A CN102170898 A CN 102170898A CN 2009801387748 A CN2009801387748 A CN 2009801387748A CN 200980138774 A CN200980138774 A CN 200980138774A CN 102170898 A CN102170898 A CN 102170898A
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China
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mdp
radiation
microparticles
microgranule
treatment
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Pending
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CN2009801387748A
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English (en)
Chinese (zh)
Inventor
弗兰克·B·格尔德
吉莲·艾利森·韦伯斯特
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Innate Therapeutics Ltd
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Innate Therapeutics Ltd
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Publication of CN102170898A publication Critical patent/CN102170898A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1094—Shielding, protecting against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
CN2009801387748A 2008-09-30 2009-09-30 用于辐射暴露治疗的组合物和方法 Pending CN102170898A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ571665A NZ571665A (en) 2008-09-30 2008-09-30 Compositions and methods for treatment of radiation exposure utilising cross-linked muramyl dipeptide microparticles
NZ571665 2008-09-30
PCT/NZ2009/000207 WO2010039048A1 (en) 2008-09-30 2009-09-30 Compositions and methods for treatment of radiation exposure

Publications (1)

Publication Number Publication Date
CN102170898A true CN102170898A (zh) 2011-08-31

Family

ID=42073685

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801387748A Pending CN102170898A (zh) 2008-09-30 2009-09-30 用于辐射暴露治疗的组合物和方法

Country Status (10)

Country Link
US (1) US10232010B2 (https=)
EP (1) EP2349311B1 (https=)
JP (2) JP6053283B2 (https=)
CN (1) CN102170898A (https=)
AU (1) AU2009300442B2 (https=)
BR (1) BRPI0913783A2 (https=)
CA (1) CA2738622C (https=)
ES (1) ES2435438T3 (https=)
NZ (1) NZ571665A (https=)
WO (1) WO2010039048A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108273038A (zh) * 2018-03-16 2018-07-13 中国人民解放军军事科学院军事医学研究院 防治肠型放射病的药物组合物
CN111060697A (zh) * 2019-02-24 2020-04-24 中国疾病预防控制中心辐射防护与核安全医学所 一种利用hmgb1的小肠放射性损伤标记方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017059486A1 (en) * 2015-10-06 2017-04-13 Innate Immunotherapeutics Limited Compositions and methods for the treatment of epilepsy
CA2926507A1 (en) * 2015-10-06 2017-04-06 Innate Immunotherapeutics Limited Compositions and methods for protection and/or repair of the nervous system
WO2017070731A1 (en) * 2015-10-28 2017-05-04 Innate Immunotherapeutics Limited Compositions and methods for the treatment of alzheimer's disease
WO2022150763A1 (en) * 2021-01-11 2022-07-14 The George Washington University Nanoparticle-mediated immune cell manufacture and uses thereof
JP2024511277A (ja) 2021-02-19 2024-03-13 メビオン・メディカル・システムズ・インコーポレーテッド 粒子線治療システムのためのガントリー

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1234078A (zh) * 1996-10-10 1999-11-03 探针国际公司 治疗病毒感染的组合物及方法
WO2000024378A1 (en) * 1998-10-23 2000-05-04 Polyheal Ltd Compositions of microspheres for wound healing

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4815446A (en) * 1985-05-09 1989-03-28 Alpha Therapeutic Corporation Process for treating metastasis of cancerous tumors
ATE303160T1 (de) * 1993-08-11 2005-09-15 Jenner Technologies Impfstoff gegen prostatakrebs
GB9320820D0 (en) * 1993-10-08 1993-12-01 Biokine Tech Ltd Compounds for medicinal use
JP5662309B2 (ja) * 2008-04-01 2015-01-28 イネイト・イムノセラピューティクス・リミテッド 腫瘍性疾患を治療するための組成物および方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1234078A (zh) * 1996-10-10 1999-11-03 探针国际公司 治疗病毒感染的组合物及方法
WO2000024378A1 (en) * 1998-10-23 2000-05-04 Polyheal Ltd Compositions of microspheres for wound healing

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
B.B.C.YOUAN: "Protein-loaded poly(e-caprolactone) microparticles.II. Muramyl dipeptide for oral controlled release of adjuvant", 《J. MICROENCAPSULATION》 *
ICHIOR AZUMA: "REVIEW: INDUCER OF CYTOKINES IN VIVO: OVERVIEW OF FIELD AND ROMURTIDE EXPERIENCE", 《INT. J. LMMUNOPHARMAC.》 *
ICHIOR AZUMA: "Synthetic immunoadjuvants:application to non-specific host stimulation and potentiation of vaccine immunogenicity", 《VACCINE》 *
JAROSLAV TURANEK ET AL.: "STIMULATION OF HAEMOPOIESIS AND PROTECTION OF MICE AGAINST RADIATION INJURY BY SYNTHETIC ANALOGUES OF MURAMYLDIPEPTIDE INCORPORATED IN LIPOSOMES", 《INT. J. LMMUNOPHARMAC.》 *
NAVNEET PURI ET AL.: "An investigation of the intradermal route as an e€ective means of immunization for microparticulate vaccine delivery systems", 《VACCINE》 *
钟英英: "天然免疫调节肽的研究概况", 《重庆科技学院学报（自然科学版）》 *
齐子荣: "胞壁酰二肽的生物学作用", 《中国人民解放军军事医学科学院院刊》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108273038A (zh) * 2018-03-16 2018-07-13 中国人民解放军军事科学院军事医学研究院 防治肠型放射病的药物组合物
CN111060697A (zh) * 2019-02-24 2020-04-24 中国疾病预防控制中心辐射防护与核安全医学所 一种利用hmgb1的小肠放射性损伤标记方法

Also Published As

Publication number Publication date
ES2435438T3 (es) 2013-12-19
US10232010B2 (en) 2019-03-19
NZ571665A (en) 2011-01-28
US20110236346A1 (en) 2011-09-29
AU2009300442A1 (en) 2010-04-08
JP6053283B2 (ja) 2016-12-27
JP2012504161A (ja) 2012-02-16
BRPI0913783A2 (pt) 2016-11-01
AU2009300442B2 (en) 2014-03-13
CA2738622C (en) 2016-10-18
EP2349311A4 (en) 2012-07-04
EP2349311B1 (en) 2013-08-21
WO2010039048A1 (en) 2010-04-08
CA2738622A1 (en) 2010-04-08
JP2016026157A (ja) 2016-02-12
EP2349311A1 (en) 2011-08-03

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Application publication date: 20110831