CN102166340A - 治疗实热性水肿的中药组合物 - Google Patents
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Abstract
本发明是一种治疗实热性水肿的中药组合物，其处方为：麻黄10-20份，桂枝10-20份，杏仁10-20份，生石膏20-30份，生姜10-20份，大枣10-20份，蒲公英10-20份，鱼腥草8-12份，灸甘草8-12份；所述的份均指重量份。服用本发明的药能散寒解表，缓解表实无汗，里热烦燥，利水消肿。从根本上治疗实热性水肿，治疗周期短，治疗效果理想。经临床应用取得了明显的临床效果，治愈率达91.5％，总有效率达到97.9％，无明显毒副作用。
Description
技术领域
本发明涉及一种治疗实热性水肿的中药组合物，属纯中草药。
背景技术
实热性水肿，中医称为溢饮，即风水水肿病，其特征是：饮水流行，归于四肢，当汗而不汗，身体疼痛，肢体浮肿。目前西医以利尿剂治疗，效果不理想，且长期服用可导致水肿加重或电解质紊乱。其它药物虽能取得一定疗效，但有较大的毒副作用，且成本高。存在治疗效果不能令人满意的缺陷。
发明内容
本发明所要解决的技术问题是，提供一种治疗实热性水肿的中药组合物，通过散寒解表，缓解表实无汗，里热烦燥，从根本上治疗实热性水肿，以克服现有治疗该类疾病药品的缺陷。
本发明解决上述技术问题所采用的技术方案如下：
治疗实热性水肿的中药组合物，其特征在于其处方为：麻黄10-20份，桂枝10-20份，杏仁10-20份，生石膏20-30份，生姜10-20份，大枣10-20份，蒲公英10-20份，鱼腥草8-12份，灸甘草8-12份；所述的份均指重量份。
优选的处方是：麻黄15份，桂枝15份，杏仁25份，生石膏25份，生姜15份，大枣15份，蒲公英15份，鱼腥草10份，灸甘草10份。
本发明方剂主要的中草药根据传统医学及现代医学分析，药性及药理作用如下：
麻黄：性味归经：温；辛、微苦；归肺、膀胱经。功能主治：发汗解表，宣肺平喘，利水消肿。用于风寒感冒，胸闷喘咳，风水浮肿；支气管哮喘。
桂枝：性味归经：温；辛、甘；归心、肺、膀胱经。功能主治：发汗解肌，温通经脉，助阳化气。用于风寒感冒，腕腹冷痛，血寒经闭，关节痹痛，痰饮，水肿，心悸，奔豚。
杏仁：性味归经：微温；苦；归肺、大肠经；小毒。功能主治：降气止咳平喘，润肠通便。用于咳嗽气喘，胸满痰多，血虚津枯，肠燥便秘。
生石膏：性味归经：大寒；辛、甘；归肺、胃经。功能主治：清热泻火，除烦止渴。用于外感热病，高热烦渴，肺热喘咳，胃火亢盛，头痛，牙痛。
生姜：性味归经：微温；辛；归肺、脾、胃经。功能主治：解表散寒，温中止呕，化痰止咳。用于风寒感冒，胃寒呕吐，寒痰咳嗽。
大枣：性味归经：温；甘；归脾、胃经。功能主治：补中益气，养血安神。用于脾虚食少，乏力便溏，妇人脏燥。
蒲公英：性味归经：寒；甘、苦；归肝、胃经。功能主治：清热解毒，消肿散结，利尿通淋。用于疔疮肿毒，乳痈，瘰疬，目赤，咽痛，肺痈，肠痈，湿热黄疸，热淋涩痛。
鱼腥草：性味归经：微寒；辛；归肺经。功能主治：清热解毒，消痈排浓，利尿通淋。用于肺痈吐脓，痰热喘咳，热痢，热淋，痈肿疮毒。
灸甘草：性味归经：平；甘；归心、肺、脾、胃经。功能主治：补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
方解：本方是治疗实热性水肿的组方，寒邪侵入人体，表寒外束，郁热不宣，除表症外，又有烦躁见症，表现为里热，即实热，郁热不宣，毛窍紧闭，汗液不能向外蒸发，表现为水肿。方中麻黄疏表宣肺以发表平喘为主药。桂枝温经通阳，发汗解肌，表气和，温煦四肢，解除肢体酸痛。杏仁宣降肺气协助麻黄止咳平喘。石膏取其清内热，出烦躁。甘草，加生姜、大枣，是和中气，调营卫，兼助发汗，且姜枣合用既可解表邪而和胃气，又能散水气而不致伤津。蒲公英与鱼腥草都能增强清热解毒之力，利尿通淋。甘草佐之，统方增效。
本发明的积极效果在于：通过服用本发明的药能散寒解表，通过散寒解表，缓解表实无汗，里热烦燥，从根本上治疗实热性水肿，治疗周期短，治疗效果理想。
经临床应用取得了明显的临床效果，治愈率达91.5％，总有效率达到97.9％，无明显毒副作用。
具体实施方式
下面结合具体实例进一步说明本发明。
处方实例一：
取麻黄10份，桂枝10份，杏仁10份，生石膏20份，生姜10份，大枣10份，蒲公英10份，鱼腥草8份，灸甘草8份混合粉碎成100目颗粒，烘烤，分装成袋每袋20克。
服法及用法：开水冲服，每日2次，发汗。
处方实例二：
麻黄15份，桂枝15份，杏仁15份，生石膏25份，生姜15份，大枣15份，蒲公英15份，鱼腥草10份，灸甘草10份.。制法及服法同实施例一。
处方实例三：
麻黄20份，桂枝20份，杏仁20份，生石膏30份，生姜20份，大枣20份，蒲公英20份，鱼腥草12份，灸甘草12份。制法及服法同实施例一。
以下是临床报告
自2008年1月至2011年1月，发明人在烟台福山区人民医院应用本发明处方实例二治疗实热性水肿患者47例，并与同期应用甲状腺素补充治疗47例进行对照观察，收到较好效果，现报告如下。
(I)、临床资料
所有病例均为莱州市人民医院门诊患者，诊断标准为中医辨证参考《国家标准应用中医内科疾病诊疗常规》，病员双下肢水肿，或脸及上身浮肿，无汗或少汗，身体困重、纳呆或伴脘腹胀闷，舌红，苔黄腻，脉滑数，共94例，选择均排除心、肝、肾等脏器疾患，营养缺乏性疾病等而确定。按就诊序号(约1∶1)随机分成两组，治疗组47例，其中男12例，女35例；年龄为34-60岁(平均45岁)；病程1-6个月(平均3个月)。对照组47例，男11例，女36例；年龄36-58岁(平均44岁)；病程1-6个月(平均3个月)。两组年龄、性别、病程及病情经统计学处理，无显著性差异，具有可比性(P＞0.05)。
(II)、治疗方法
1、治疗方案治疗组给予本发明组方实热性水肿冲剂开水冲服，每日2剂，发汗。7天为一个疗程。对照组口服甲状腺素治疗每次1-2mg，每日3次，7天为一个疗程。
2、观察指标症状：无汗，浑身酸痛、肿胀，身体困重、纳呆或伴脘腹胀闷，舌红，苔黄腻，脉滑数，观测治疗前后之变化。服药期间临床症状及体征每日记录1次，不良反应随时记录。
3、统计学处理：组间百分率比较采用x 2检验，组间均数比较用方差分析t检验。
(III)、疗效标准
疗效判别标准：根据《中医临床病证诊断疗效标准》水肿疗效评定标准拟定。治愈：水肿全部消退，其他症状消失；好转：水肿及其他症状减轻；无效：水肿及其他症状无变化。
(IV)、治疗结果
治疗结果治疗组47例患者经1～2个疗程后，治愈43例(91.5％)，好转3例(6.4％)，无效1例(2.1％)。
两组总疗效比较表
两组疗效比较P＜0.05。
由此可见，本发明的药对于治疗实热性水肿效果优于其它药物，治愈有效率高。
典型病例
刘某，女，47岁，于2009年10月7日初诊。双下肢浮肿2月，无汗，脸时常肿胀，伴身体困重，口苦，纳差。查其双胫前及踝关节以下按之凹陷难复，舌红、苔黄腻，脉滑数。肝功能、小便常规、肾功能及心电图、血FT3、FT4无异常，血压正常。中医辨病为实热性水肿。药用本发明实施例二方剂每日1剂，水冲服。6剂服毕，水肿明显消退，余症皆消。随访5个月未复发。
Claims (2)
1.治疗实热性水肿的中药组合物，其特征在于其处方为：麻黄10-20份，桂枝10-20份，杏仁10-20份，生石膏20-30份，生姜10-20份，大枣10-20份，蒲公英10-20份，鱼腥草8-12份，灸甘草8-12份；所述的份均指重量份。
2.如权利要求1所述的治疗实热性水肿的中药组合物，其特征在于其处方为：麻黄15份，桂枝15份，杏仁15份，生石膏25份，生姜15份，大枣15份，蒲公英15份，鱼腥草10份，灸甘草10份。
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| CN115869371A (zh) * | 2022-11-10 | 2023-03-31 | 魏庆安 | 一种经络调理液 |
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| CN1465389A (zh) * | 2002-06-21 | 2004-01-07 | 南京凯优科贸有限公司 | 大青龙汤药物制剂及其制备 |
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| CN1465389A (zh) * | 2002-06-21 | 2004-01-07 | 南京凯优科贸有限公司 | 大青龙汤药物制剂及其制备 |
Non-Patent Citations (2)
| Title |
|---|
| 《中医药学刊》 19891231 胡炳文 胡万魁先生《古方今病》选录 , 第05期 * |
| 《甘肃中医》 20100630 任希海等 大青龙汤证刍议 第3-4页 1-2 第23卷, 第6期 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115869371A (zh) * | 2022-11-10 | 2023-03-31 | 魏庆安 | 一种经络调理液 |
| CN115869371B (zh) * | 2022-11-10 | 2024-04-19 | 魏庆安 | 一种经络调理液 |
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