CN102159241A - 用于增强免疫应答的泰帕森(Tapasin)增加 - Google Patents

用于增强免疫应答的泰帕森(Tapasin)增加 Download PDF

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Publication number
CN102159241A
CN102159241A CN2009801031574A CN200980103157A CN102159241A CN 102159241 A CN102159241 A CN 102159241A CN 2009801031574 A CN2009801031574 A CN 2009801031574A CN 200980103157 A CN200980103157 A CN 200980103157A CN 102159241 A CN102159241 A CN 102159241A
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cancer
carcinoma
medicament
cell
cells
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Chinese (zh)
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威尔弗雷德·杰弗里斯
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TAPIMMUNE Inc
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TAPIMMUNE Inc
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
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    • A61P31/14Antivirals for RNA viruses
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5152Tumor cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5156Animal cells expressing foreign proteins
    • AHUMAN NECESSITIES
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
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    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Wood Science & Technology (AREA)
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  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2009801031574A 2008-01-28 2009-01-27 用于增强免疫应答的泰帕森(Tapasin)增加 Pending CN102159241A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2400408P 2008-01-28 2008-01-28
US61/024,004 2008-01-28
PCT/IB2009/005030 WO2009095796A2 (en) 2008-01-28 2009-01-27 Tapasin augmentation for enhanced immune response

Publications (1)

Publication Number Publication Date
CN102159241A true CN102159241A (zh) 2011-08-17

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ID=40913348

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CN2009801031574A Pending CN102159241A (zh) 2008-01-28 2009-01-27 用于增强免疫应答的泰帕森(Tapasin)增加

Country Status (8)

Country Link
US (1) US20110117137A1 (https=)
EP (1) EP2247309A4 (https=)
JP (2) JP2011518115A (https=)
KR (1) KR20110011595A (https=)
CN (1) CN102159241A (https=)
AU (1) AU2009208735A1 (https=)
CA (1) CA2712964A1 (https=)
WO (1) WO2009095796A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021515588A (ja) 2018-01-26 2021-06-24 ケンブリッジ エンタープライズ リミティッド ペプチド交換蛋白質

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4418965B2 (ja) * 1994-09-23 2010-02-24 タップイミューン・インコーポレイテッド 内在性ペプチドを有するmhcクラスi分子の発現を増強する方法
US6171820B1 (en) * 1995-12-07 2001-01-09 Diversa Corporation Saturation mutagenesis in directed evolution
US6713279B1 (en) * 1995-12-07 2004-03-30 Diversa Corporation Non-stochastic generation of genetic vaccines and enzymes
US6479258B1 (en) * 1995-12-07 2002-11-12 Diversa Corporation Non-stochastic generation of genetic vaccines
US6692923B2 (en) * 1999-04-14 2004-02-17 Incyte Corporation Tapasin-like protein
EP1363938B1 (en) * 2000-08-03 2013-12-11 Johns Hopkins University Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen
JP2004517917A (ja) * 2000-11-08 2004-06-17 アルバート・アインシュタイン・カレッジ・オブ・メディシン・オブ・イエシヴァ・ユニバーシティー 星状細胞及び星状細胞性腫瘍細胞の増殖を阻害する方法とその使用
GB0328248D0 (en) * 2003-12-05 2004-01-07 Oxford Biomedica Ltd Method

Also Published As

Publication number Publication date
CA2712964A1 (en) 2009-08-06
JP2014196338A (ja) 2014-10-16
EP2247309A4 (en) 2013-10-16
JP2011518115A (ja) 2011-06-23
EP2247309A2 (en) 2010-11-10
US20110117137A1 (en) 2011-05-19
AU2009208735A1 (en) 2009-08-06
WO2009095796A3 (en) 2013-01-03
KR20110011595A (ko) 2011-02-08
WO2009095796A2 (en) 2009-08-06

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Application publication date: 20110817