CN102144664A - Solid hydrogen peroxide sustained release preparation and preparation method thereof - Google Patents
Solid hydrogen peroxide sustained release preparation and preparation method thereof Download PDFInfo
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- CN102144664A CN102144664A CN2010106058135A CN201010605813A CN102144664A CN 102144664 A CN102144664 A CN 102144664A CN 2010106058135 A CN2010106058135 A CN 2010106058135A CN 201010605813 A CN201010605813 A CN 201010605813A CN 102144664 A CN102144664 A CN 102144664A
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Abstract
The invention relates to a sustained release preparation and a preparation method thereof and particularly discloses a solid hydrogen peroxide sustained release preparation and a preparation method thereof. The solid hydrogen peroxide sustained release preparation is characterized by being prepared by taking a solid hydrogen peroxide adduct as a main agent and adding solid weak acid, water absorbing materials and auxiliaries according to a certain proportion, wherein the weight percentages of all the components are as follows: 0.1-99% of the solid hydrogen peroxide adduct, 0.1-98% of the solid weak acid, 0-98% of the water absorbing materials and 0-98% of the auxiliaries. The solid hydrogen peroxide sustained release preparation and the preparation method thereof which are provided by the invention have the beneficial effects that: the solid hydrogen peroxide sustained release preparation can be conveniently used for food sterilization and fruit and vegetable preservation and can be stored for a long term and the solid hydrogen peroxide adduct releases hydrogen peroxide when encountering water and is easy to control; the release speed and the sustained-release period of the hydrogen peroxide can be regulated according to needs; the sustained release preparation is simple in production and has small investment and low cost; and the solid hydrogen peroxide sustained release preparation is a solid powdered product and can be conveniently stored and transported.
Description
(1) technical field
The present invention relates to a kind of sustained release agent and preparation method thereof, particularly a kind of solid peroxygen hydrogen sustained release agent and preparation method thereof.
(2) background technology
Hydrogen peroxide is a kind of inorganic matter, belongs to stronger oxidant, and acid condition helps the stable of hydrogen peroxide.Hydrogen peroxide is a kind of high-effective disinfecting, bactericide, is widely used in fields such as wound disinfection and environment, food sterilization.
Hydrogen peroxide is applied to the history in existing more than 100 year in sterilization field, but the example that is used for food-processing industry and preserving fruit and vegetable utilizing success is seldom, and its main cause has the following aspects: the one, and the hydrogen peroxide natural decomposition is fast, does not reach the effect of fresh-keeping requirement; The 2nd, the preparation facilities use of hydrogen peroxide steam is inconvenient, cost is high.Above-mentioned reason brings inconvenience for production, storage, transportation and the use of hydrogen peroxide, has limited the application of hydrogen peroxide.The production and sales of hydrogen peroxide product are arranged on the market, such as the preparation described in the patent CN1047064C (publication number) based on the antistaling agent that contains the number of chemical composition of hydrogen peroxide, comprising the number of chemical composition all nontoxic, free from extraneous odour produces, bactericidal effect is good, has tangible advantage than disinfectant chloride, element sulphur; Be to be to utilize slow release method that bactericide is prepared into emulsion described in the fresh-keeping aqueous emulsion patent of disinfectant with hydrogen peroxide of 1234175A as publication number, improve drug effect, need the water distribution dilution during use, fruits and vegetables dipping or be sprayed at fruit and vegetable surfaces; Publication number is to utilize the hydrogen peroxide steam disinfectant method in the patent of CN1033941A for another example, mainly be under predetermined temperature, sealing disinfection room with hydrogen peroxide and water vapor mixture input predetermined, reach the saturation limit of vapour mixture, a kind of vapor phase hydrogen peroxide sterilization is provided.Above-mentioned patent is all improved aspects such as the transportation of hydrogen peroxide, use, safety, and hydrogen peroxide quantitatively discharges and the problem of stability but all do not solve, and has limited the application of hydrogen peroxide, has also brought inconvenience to the user.
(3) summary of the invention
The present invention is in order to remedy the deficiencies in the prior art, provide plant easy to use, be convenient to solid peroxygen hydrogen sustained release agent that transports storage and preparation method thereof.
The present invention is achieved through the following technical solutions:
A kind of solid peroxygen hydrogen sustained release agent, it is characterized in that: with solid peroxygen hydrogen adduct is host, adding solid weak acid, absorbent material and auxiliary agent by certain proportioning forms, wherein the percentage by weight between each component is: solid peroxygen hydrogen adduct 0.1～99%, solid weak acid 0.1～98%, absorbent material 0～98%, auxiliary agent 0～98%.
Described solid peroxygen hydrogen adduct is meant and is in percarbonate, perphosphate or the perborate of sodium, potassium, calcium, magnesium etc. one or more that wherein preferred, solid peroxygen hydrogen adduct is a SODIUM PERCARBONATE.
Described solid weak acid is that boric acid, citric acid, malic acid, tartaric acid etc. are met water and shown one or more combination in the faintly acids.
Described absorbent material can be a) one or more polymer; Or b) one or more deliquescent compositions; Or c) its mixture, one or more in preferred anhydrous calcium chloride, anhydrous magnesium sulfate, anhydrous magnesium chloride, silica gel, silica or the hydroscopic high-molecular resin.
Described auxiliary agent is one or more in talcum powder, potter's clay, starch, cellulose, diatomite, stearic acid or the white carbon.
The preparation method of solid peroxygen hydrogen sustained release agent of the present invention, its special character is: comprise the steps:
Under drying condition, solid peroxygen hydrogen adduct, solid weak acid, absorbent material and auxiliary agent are mixed according to described ratio, needs according to food sterilization or preserving fruit and vegetable utilizing, use packaging material that mixed powder is processed into the inner wrapping product of constant weight, the high-barrier polybag of then converted products being packed into is stored and is transported.
Described packaging material can be selected from wet, ventilative thoroughly packaging material such as compound nonwoven cloth, nonwoven, tea filter paper, punching paper and plastics compound bag, and punch density is for to make a call to a hole every the 5-15 millimeter, and pore size is that needle point has just been pricked till the not saturating powder.
The solid peroxygen hydrogen sustained release agent for preparing need be opened the external packing plastic film bag in use, the sustained release agent cartridge bag is put into required sterilization or the sealing of fresh-keeping container gets final product.
The effect of absorbent material is the moisture in the auxiliary absorbing environmental, for hydrogen peroxide adduct provides reaction medium water.When absorbent material was 0, this product also can be realized, still preferably contains the prescription of absorbent material.
The effect of auxiliary agent is the stability that improves product, helps the production, processing of product etc., and when auxiliary agent was 0, this product also can realize, but preferably contains the prescription of auxiliary agent.
The present invention is being on the basis of main component with solid peroxygen hydrogen adduct, has increased one or more solid weak acid, absorbent material and the auxiliary agent that can make hydrogen peroxide stable.Under the condition of drying, it is mixed, will mix the back powder as required and use packaging material to be packaged into the product of different size, store and transport in the polybag of the high barrier of then product being packed into.Under dry status, hydrogen peroxide adduct self is not emitted hydrogen peroxide, and solid acid does not react no hydrogen peroxide generation with hydrogen peroxide adduct.When the needs hydrogen peroxide produces, open external packing, moisture in the absorbent material absorbing environmental, the medium-water that has chemical reaction to need, solid peroxygen hydrogen adduct is emitted hydrogen peroxide after meeting water.The hydrogen peroxide that exists for of solid acid provides a stable environment.By the absorption speed of control absorbent material, with regard to the rate of release of controlled preparing hydrogen peroxide.Inner packaging material can be selected wet, ventilative thoroughly packaging material such as compound nonwoven cloth, nonwoven, tea filter paper, punching paper and plastics compound bag for use.
The beneficial effect of solid peroxygen hydrogen sustained release agent of the present invention and preparation method thereof: solid peroxygen hydrogen sustained release agent is used for food sterilization and preserving fruit and vegetable utilizing, and is easy to use, and hydrogen peroxide adduct is met water and promptly discharged hydrogen peroxide, is easy to control; The rate of release of hydrogen peroxide and slowly-releasing cycle can be regulated as required; But long term storage; Produce simply, drop into for a short time, cost is low; Be the solid powdery product, storing is convenient.
(4) specific embodiment
Following examples are to further specify of the present invention, but the present invention is not limited thereto.
Embodiment 1:
Solid peroxygen hydrogen sustained release agent prescription: SODIUM PERCARBONATE 80 grams, citric acid 20 grams.
The preparation method of this solid peroxygen hydrogen sustained release agent, adopt following steps: under drying condition, drying, pulverous SODIUM PERCARBONATE 80 grams and citric acid 20 grams are mixed, with the powder that mixes, use the punching compound nonwoven cloth to pack, make the finished product of 2 gram/bags, the plastic bag sealing of packing into storing.
Embodiment 2:
Solid peroxygen hydrogen sustained release agent prescription: potassium superphosphate 50 grams, citric acid 30 grams, anhydrous calcium chloride 20 grams.
The preparation method of this solid peroxygen hydrogen sustained release agent, adopt following steps: under drying condition, drying, pulverous potassium superphosphate 50 grams, citric acid 30 grams, anhydrous calcium chloride 20 grams are mixed, with the powder that mixes, use tea filter paper to pack, make the finished product of 5 gram/bags, the plastic bag sealing of packing into storing.
Embodiment 3:
Solid peroxygen hydrogen sustained release agent prescription: sodium perborate 60 grams, tartaric acid 30 grams, talcum powder 10 grams.
The preparation method of this solid peroxygen hydrogen sustained release agent, adopt following steps: under drying condition, drying, Powdered sodium perborate 60 grams, tartaric acid 30 grams and talcum powder 10 grams are mixed, with the powder that mixes, use nonwoven to pack, make the finished product of 3.0 gram/bags, the plastic bag sealing of packing into storing.
Embodiment 4:
Solid peroxygen hydrogen sustained release agent prescription: calcium superphosphate 50 grams, boric acid 30 grams, anhydrous magnesium chloride 10 grams, white bole 10 grams.
The preparation method of this solid peroxygen hydrogen sustained release agent, adopt following steps: under drying condition, drying, Powdered calcium superphosphate 50 grams, boric acid 30 grams, anhydrous magnesium chloride 10 grams and white bole 10 grams are mixed, with the powder that mixes, use the punching compound nonwoven cloth to pack, make the finished product of 1.0 gram/bags, the plastic bag sealing of packing into storing.
Embodiment 5:
Solid peroxygen hydrogen sustained release agent prescription: SODIUM PERCARBONATE 0.1 gram, malic acid 98 grams, anhydrous magnesium chloride 1.2 grams, diatomite 0.7 gram.
The preparation method of this solid peroxygen hydrogen sustained release agent, adopt following steps: under drying condition, drying, Powdered SODIUM PERCARBONATE 0.1 gram, malic acid 98 grams, anhydrous magnesium chloride 1.2 grams and diatomite 0.7 gram are mixed, with the powder that mixes, use the punching compound nonwoven cloth to pack, make the finished product of 10 gram/bags, the plastic bag sealing of packing into storing.
Embodiment 6:
Solid peroxygen hydrogen sustained release agent prescription: SODIUM PERCARBONATE 99 grams, boric acid 0.1 gram, anhydrous calcium chloride 0.6 gram, talcum powder 0.3 gram.
Other operations are with embodiment 4.
Embodiment 7:
Solid peroxygen hydrogen sustained release agent prescription: SODIUM PERCARBONATE 1 gram, malic acid 1 gram, anhydrous calcium chloride 49 grams, anhydrous magnesium sulfate 49 grams.
Other operations are with embodiment 4.
Embodiment 8:
Solid peroxygen hydrogen sustained release agent prescription: SODIUM PERCARBONATE 25 grams, citric acid 15 grams, anhydrous calcium chloride 20 grams, white carbon 10 grams, talcum powder 30 grams.
Other operations are with embodiment 3.
Embodiment 9:
Solid peroxygen hydrogen sustained release agent prescription: SODIUM PERCARBONATE 1 gram, boric acid 0.5 gram, anhydrous magnesium sulfate 0.5 gram, white carbon 98 grams.
Other operations are with embodiment 5.
Embodiment 10:
The solid peroxygen hydrogen sustained release agent that embodiment of the invention 1-9 is made is loaded in the packaging material of pricking the hole, places 25 ℃, the air of relative humidity 70% then, through different time, and remaining content of hydrogen peroxide such as following table:
As can be seen from the above table, various products all can discharge most hydrogen peroxide at short notice among the embodiment 1-9.
Embodiment 11:
Mango is handled through the ethene ripener after plucking, accelerate the ripening when finishing, solid peroxygen hydrogen sustained release agent with present embodiment 8 preparations, tear outer packaging bag, put into 2 bags in every case, normal temperature was placed 7 days, with the mango contrast of not placing sustained release agent, contrast mango has 20% scab or rotten to occur, and the mango that sustained release agent is handled the scab ratio occurs less than 5%, illustrates that sustained release agent can obviously suppress microorganism diseases such as mango anthracnose.
Claims (9)
1. solid peroxygen hydrogen sustained release agent, it is characterized in that: with solid peroxygen hydrogen adduct is host, adding solid weak acid, absorbent material and auxiliary agent by certain proportioning forms, wherein the percentage by weight between each component is: solid peroxygen hydrogen adduct 0.1～99%, solid weak acid 0.1～98%, absorbent material 0～98%, auxiliary agent 0～98%.
2. solid peroxygen hydrogen sustained release agent according to claim 1 is characterized in that: one or more in percarbonate, perphosphate or the perborate that described solid peroxygen hydrogen adduct is sodium, potassium, calcium, magnesium.
3. solid peroxygen hydrogen sustained release agent according to claim 2 is characterized in that: described solid peroxygen hydrogen adduct is a SODIUM PERCARBONATE.
4. solid peroxygen hydrogen sustained release agent according to claim 1 is characterized in that: described solid weak acid is one or more the combination in boric acid, citric acid, malic acid or the tartaric acid.
5. solid peroxygen hydrogen sustained release agent according to claim 1, it is characterized in that: described absorbent material is one or more polymer, one or more deliquescent compositions or the above two mixture.
6. solid peroxygen hydrogen sustained release agent according to claim 5 is characterized in that: described absorbent material is one or more in anhydrous calcium chloride, anhydrous magnesium sulfate, anhydrous magnesium chloride, silica gel, silica or the hydroscopic high-molecular resin.
7. solid peroxygen hydrogen sustained release agent according to claim 1 is characterized in that: described auxiliary agent is one or more in talcum powder, potter's clay, starch, cellulose, diatomite, stearic acid or the white carbon.
8. the preparation method of solid peroxygen hydrogen sustained release agent according to claim 1 is characterized in that: comprise the steps:
Under drying condition, solid peroxygen hydrogen adduct, solid weak acid, absorbent material and auxiliary agent are mixed according to described ratio, use packaging material that mixed powder is processed into the inner wrapping product, the high-barrier polybag of then converted products being packed into is stored and is transported.
9. the preparation method of solid peroxygen hydrogen sustained release agent according to claim 8 is characterized in that: described packaging material are compound nonwoven cloth, nonwoven, tea filter paper or punching paper and plastics compound bag.
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| CN201010605813A CN102144664B (en) | 2010-12-27 | 2010-12-27 | Solid hydrogen peroxide sustained release preparation and preparation method thereof |
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| CN201010605813A CN102144664B (en) | 2010-12-27 | 2010-12-27 | Solid hydrogen peroxide sustained release preparation and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102350186A (en) * | 2011-07-18 | 2012-02-15 | 王�锋 | Moistureproof pressure-maintaining drying agent |
| CN102845514A (en) * | 2012-09-22 | 2013-01-02 | 山东营养源食品科技有限公司 | Method for inhibiting Huangguan pear pericarp browning |
| CN104496015A (en) * | 2014-12-23 | 2015-04-08 | 东南大学 | Micro-capsule sustained-release oxygenation bacteria filter tank and oxygenation method |
| CN104667981A (en) * | 2015-01-15 | 2015-06-03 | 鲁昱瑶 | Catalyst for preparing oxygen from hydrogen peroxide, as well as preparation method and experiment method of catalyst |
| CN106359557A (en) * | 2016-11-18 | 2017-02-01 | 新疆农业科学院农产品贮藏加工研究所 | Hydrogen peroxide active oxygen fruit and vegetable preservative as well as preparation method and application thereof |
| WO2021253598A1 (en) * | 2020-06-18 | 2021-12-23 | 江苏南京农大动物药业有限公司 | Solid hydrogen peroxide and preparation method therefor and use thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1047064C (en) * | 1994-07-28 | 1999-12-08 | 关键生 | Antiseptic disinfectant with hydrogen peroxide |
| JP2005006278A (en) * | 2003-06-12 | 2005-01-06 | Sk Telecom Kk | Power allocation apparatus and method for packet data services in mobile communication systems |
| CN101766215A (en) * | 2009-01-07 | 2010-07-07 | 管永红 | Quince preservative |
-
2010
- 2010-12-27 CN CN201010605813A patent/CN102144664B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1047064C (en) * | 1994-07-28 | 1999-12-08 | 关键生 | Antiseptic disinfectant with hydrogen peroxide |
| JP2005006278A (en) * | 2003-06-12 | 2005-01-06 | Sk Telecom Kk | Power allocation apparatus and method for packet data services in mobile communication systems |
| CN101766215A (en) * | 2009-01-07 | 2010-07-07 | 管永红 | Quince preservative |
Non-Patent Citations (1)
| Title |
|---|
| 戚渭新等: "应用于洗涤剂工业的高稳定过碳酸钠研究进展", 《日用化学工业》 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102350186A (en) * | 2011-07-18 | 2012-02-15 | 王�锋 | Moistureproof pressure-maintaining drying agent |
| CN102350186B (en) * | 2011-07-18 | 2014-04-09 | 唐山远腾自动化设备有限公司 | Application of moistureproof pressure-maintaining drying agent in instrument with good seal in humid or underwater environment |
| CN102845514A (en) * | 2012-09-22 | 2013-01-02 | 山东营养源食品科技有限公司 | Method for inhibiting Huangguan pear pericarp browning |
| CN104496015A (en) * | 2014-12-23 | 2015-04-08 | 东南大学 | Micro-capsule sustained-release oxygenation bacteria filter tank and oxygenation method |
| CN104496015B (en) * | 2014-12-23 | 2016-04-06 | 东南大学 | A kind of microcapsule controlled-release oxygenation biological filter and oxygenation method |
| CN104667981A (en) * | 2015-01-15 | 2015-06-03 | 鲁昱瑶 | Catalyst for preparing oxygen from hydrogen peroxide, as well as preparation method and experiment method of catalyst |
| CN106359557A (en) * | 2016-11-18 | 2017-02-01 | 新疆农业科学院农产品贮藏加工研究所 | Hydrogen peroxide active oxygen fruit and vegetable preservative as well as preparation method and application thereof |
| WO2021253598A1 (en) * | 2020-06-18 | 2021-12-23 | 江苏南京农大动物药业有限公司 | Solid hydrogen peroxide and preparation method therefor and use thereof |
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| CN102144664B (en) | 2012-10-17 |
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Effective date of registration: 20230703 Address after: No. 87 Fuyang Street, Jibei Street, Jiyang District, Jinan City, Shandong Province, 251400 (600 meters west of the bus station and north of the road) Patentee after: SHANDONG AOWEITE BIOTECHNOLOGY Co.,Ltd. Address before: 251400 Fuyang Street, Jibei Development Zone, Jiyang County, Jinan City, Shandong Province Patentee before: SHANDONG NUTRIENT SOURCE FOOD TECHNOLOGY Co.,Ltd. |
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