CN102139000B - 治疗小儿单纯性消化不良外用药及其制备方法 - Google Patents
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Abstract
本发明涉及一种中药及其制备方法，尤其是一种治疗小儿单纯性消化不良外用药及其制备方法。其中药原料的组成为：丁香、肉桂、白芷、小茴香、黑胡椒、苍术、吴茱萸。将所述各成分共为细末，用温水或醋调和成泥状，搓成圆饼状。使用时，用薄纱布包裹药丸，敷在患者神阙穴处，然后用绷带或粗布条固定于腰部。该治疗小儿单纯性消化不良外用药将上述各种成分有机结合，充分发挥各种成分的药理作用，通过皮肤吸收、渗透，作用于人体，药效缓慢而平稳释放，避免口服药带来的种种不便，容易为患者接受，疗效好。
Description
技术领域
本发明涉及一种中药及其制备方法，尤其是一种治疗小儿单纯性消化不良外用药及其制备方法。
背景技术
小儿消化不良，又称婴幼儿腹泻。以大便次数增多，大便稀薄，或水样便，或食物不化，或有粘液为特征。发生年龄多在2岁以下，1岁以内者占半数。本病四季都可发生，但以夏秋季节居多，包括单纯性消化不良，中毒性消化不良，迁延性消化不良，夏季腹泻，秋季腹泻。中医学中通称为“小儿泄泻”，根据临床表现，本病可分为五类证型：伤食泻、湿热泻、寒湿泻、脾虚泻、脾肾阳虚泻。常见治疗小儿消化不良多采用口服药，喂药困难，不易被患者接受，影响了药效的发挥。
发明内容
本发明的目的是提供一种用药方便、疗效好的治疗小儿单纯性消化不良外用药及其制备方法。
本发明所述治疗小儿单纯性消化不良外用药，其特征在于中药原料的组成重量份数如下：丁香2-4g ；肉桂2-4g；白芷2-4g；小茴香2-4g；黑胡椒2-4g ；苍术7-9 g；吴茱萸14-16g。
上述治疗小儿单纯性消化不良外用药的制备方法如下，将所述各成分共为细末，用温水或醋调和成泥状，搓成直径2—2.5厘米的圆球状，挤压成厚度0.3-—0.5厘米的圆饼状。
上述制备方法中，取大蒜15—25克捣碎成蒜泥，将所述各成分共为细末，与蒜泥混合搓成直径2—2.5厘米的圆球状，挤压成厚度0.3-—0.5厘米的圆饼状。
上述各成分优选如下重量份数：丁香2g；肉桂2g；白芷2g；小茴香2g；黑胡椒2g；苍术7g；吴茱萸14g。
上述各成分优选如下重量份数：丁香4g ；肉桂4g；白芷4g；小茴香4g；黑胡椒4g；苍术9g；吴茱萸16g。
上述各成分优选如下重量份数：丁香3g ；肉桂3g；白芷3g；小茴香3g；黑胡椒3g；苍术8g；吴茱萸15g。
丁香，木犀科丁香属落叶灌木或小乔木。因花筒细长如钉且香故名。又称丁香、洋丁香。药用“丁香”实为桃金娘科蒲桃属植物丁香，以花蕾和其果实入药。花蕾称公丁香或雄丁香，果实称母丁香或雌丁香。在花蕾开始呈白色，渐次变绿色，最后呈鲜红色时可采集。将采得的花蕾除去花梗晒干即成。出自《开宝本草》，药性论；《雷公炮炙论》：“凡使（丁香），有雌雄，雄颗小，雌颗大，似枣核。方中多使雌，力大，膏煎中用雄。”《开宝本草》：“丁香，二月、八月采。按广州送丁香图，树高丈余，叶似栎叶，花圆细，黄色，凌冬不雕。医家所用惟用根。子如钉子，长三、四分，紫色，中有粗大如山茱萸者，为母丁香，可入心腹之药尔。”
丁香具有抗菌、驱虫、健胃、止痛以及温中、暖肾、降逆之功效，主治：治呃逆、呕吐、反胃、痢疾、心腹冷痛、痃癖、疝气、癣症。
肉桂，别名：玉桂、牡桂、菌桂、筒桂、大桂、辣桂、桂。功能：补火助阳，引火归源，散寒止痛，活血通经。主治：用于阳痿、宫冷、心腹冷痛、虚寒吐泻、经闭、痛经、温经通脉。现代医学研究证明，肉桂具有降温、降压、健胃驱风、祛痰镇咳的作用。
白芷，又名：薛、芷、芳香、苻蓠、泽芬、白茝、香白芷。性味归经：辛，温。归肺、胃经。祛风散寒，通窍止痛，消肿排脓，燥湿止带。来源中国：为伞形科植物禹白芷、兴安白芷、川白芷、杭白芷或云南牛防风的根，禹白芷主产河南禹州一带。
小茴香，别名：茴香、香丝菜、蘹香、谷茴香、谷茴、土茴香、野茴香、大茴香、谷香、香子、小香。为伞形科植物茴香的干燥成熟果实。功能主治：散寒止痛，理气和胃。活血、利气、止痛。用于胸胁院腹疼痛、经闭痛经、产后瘀阻、跌扑肿痛。现代医学研究证明，口服小茴香24mg/kg，可使胃运动出现有意义的恢复，尤以给药后30分钟和35分钟时，与对照组比较有非常显著差别。茴香油能降低胃的张力，随后又能刺激胃使之蠕动正常化，缩短排空时间。对肠则增进张力及蠕动，促进气体的排出。有时在兴奋后蠕动降低，有助于缓解痉挛、减轻疼痛。茴香油的这种作用能被局部麻醉药所取消，故其可能是神经反射性的。茴香油可作为驱风剂，在腹气胀时排除气体，减轻疼痛。小茴香对胃液分泌、应激溃疡有抑制作用；并有利胆作用，随着胆汁固体成分增加促进胆汁分泌。
胡椒分黑、白两种。但它们并非是品种不同，而是加工方法不同。黑胡椒是在果实开始变红时采收晒干的未去皮者，白胡椒是果实全部变红时采收，经水浸去皮晒干而成。 中医认为，胡椒味辛、性热、无毒，功能温中散寒、行气止痛，适用于中焦寒盛、宿食不消、脘腹冷痛、反胃呕吐、泄泻下痢等。白胡椒散寒、健胃功效更强。黑胡椒温补脾肾功效明显，可治疗由脾肾虚寒造成的五更泻。
苍术，为菊科苍术属的植物。多年生直立草本，呈不规则连珠状或结节状圆柱形，略弯曲，偶有分枝，长3～10cm，直径1～2cm。气香特异，味微甘、辛、苦。性味归经：辛、苦，温。归脾、胃、肝经。功能主治：燥湿健脾，祛风散寒，明目。用于脘腹胀满，泄泻水肿，脚气痿躄，风湿痹痛，风寒感冒，夜盲。苍术具有燥湿健脾，祛风湿、调整胃肠运动功能的功效。
吴茱萸别名吴萸、茶辣、漆辣子、臭辣子树、左力纯幽子、米辣子等。通常分大花吴茱萸、中花吴茱萸和小花吴茱萸等几个品种。吴茱萸及其变种的接近成熟的果实为常用中药。其性热味苦寒，有散热止痛、降逆止呕之功，用于治疗肝胃虚寒、阴浊上逆所致的头痛或胃腕疼痛等症。
该治疗小儿单纯性消化不良外用药将上述各种成分有机结合，充分发挥各种成分的药理作用，通过皮肤吸收、渗透，作用于人体，药效缓慢而平稳释放，避免口服药带来的种种不便，容易为患者接受，疗效好。选择100例年龄在2-7岁患者临床对比试验，用药后24小时，显效为65例，有效为35例；用药后36小时，显效为85例，有效为15例。
具体实施方式
实施例1：备药，准备如下重量份数的成分：丁香2g ；肉桂2g；白芷2g；小茴香2g；黑胡椒2g ；苍术7 g；吴茱萸14g。将所述各成分共为细末，用温水或醋调和成泥状，搓成直径2—2.5厘米的圆球状，挤压成厚度0.3-—0.5厘米的圆饼状。使用时，用薄纱布包裹药丸，敷在患者神阙穴处，然后用绷带或粗布条固定于腰部，5- 7天更换。为避免药味向外散发，可以药丸的外侧覆盖塑料布，延长药效维持的时间。
实施例2：各成分配比及制备方法同实施例1，另取大蒜15克捣碎成蒜泥，将所述各成分共为细末，与蒜泥混合，用温水或醋调和成泥状，搓成直径2—2.5厘米的圆球状，挤压成厚度0.3-—0.5厘米的圆饼状。使用方法同实施例1。
实施例3：同实施例1，其中各成分配比的重量份数为，丁香4g ；肉桂4g；白芷4g；小茴香4g；黑胡椒4g；苍术9g；吴茱萸16g，将上述各成分共为细末。另取大蒜25克，捣碎成蒜泥，将药末与蒜泥，另加适量温水调和成泥状，搓成直径2—2.5厘米的圆球状，挤压成厚度0.3-—0.5厘米的圆饼状。使用时，用薄纱布包裹药丸，敷在患者神阙穴处，然后用绷带或粗布条固定于腰部，5- 7天更换。
实施例4：同实施例3，其中组成药末的各成分重量份数为，丁香3g ；肉桂3g；白芷3g；小茴香3g；黑胡椒3g；苍术8g；吴茱萸15g。
Claims (6)
1.治疗小儿单纯性消化不良外用药，其特征在于中药原料的组成重量份数如下：丁香2-4g ；肉桂2-4g；白芷2-4g；小茴香2-4g；黑胡椒2-4g ；苍术7-9 g；吴茱萸14-16g。
2.根据权利要求1所述的治疗小儿单纯性消化不良外用药的制备方法，其特征在于：将所述各成分共为细末，用温水或醋调和成泥状，搓成直径2—2.5厘米的圆球状，挤压成厚度0.3-—0.5厘米的圆饼状。
3. 根据权利要求1所述的治疗小儿单纯性消化不良外用药的制备方法，其特征在于：取大蒜15—25克捣碎成蒜泥，将所述各成分共为细末，与蒜泥混合搓成直径2—2.5厘米的圆球状，挤压成厚度0.3-—0.5厘米的圆饼状。
4. 根据权利要求1所述的治疗小儿单纯性消化不良外用药，其特征在于中药原料的组成重量份数如下：丁香2g ；肉桂2g；白芷2g；小茴香2g；黑胡椒2g；苍术7g；吴茱萸14g。
5. 根据权利要求1所述的治疗小儿单纯性消化不良外用药，其特征在于中药原料的组成重量份数如下：丁香4g ；肉桂4g；白芷4g；小茴香4g；黑胡椒4g；苍术9g；吴茱萸16g。
6. 根据权利要求1所述的治疗小儿单纯性消化不良外用药，其特征在于中药原料的组成重量份数如下：丁香3g ；肉桂3g；白芷3g；小茴香3g；黑胡椒3g；苍术8g；吴茱萸15g。
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