CN102138984B - Intestinal motility medicinal composition - Google Patents
Intestinal motility medicinal composition Download PDFInfo
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- CN102138984B CN102138984B CN 201010539913 CN201010539913A CN102138984B CN 102138984 B CN102138984 B CN 102138984B CN 201010539913 CN201010539913 CN 201010539913 CN 201010539913 A CN201010539913 A CN 201010539913A CN 102138984 B CN102138984 B CN 102138984B
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Abstract
The invention relates to an intestinal motility medicinal composition, which is prepared from the following components in part by weight: 50 parts of Chinese pasque herb, 50 parts of parslane herb, 75 parts of wrinkled gianthyssop herb, 25 parts of meadowrue root and rhizome, 35 parts of medicine terminalia fruit, 25 parts of alum, 50 parts of Chinese white poplar, 30 parts of bistort rhizome and30 parts of szechuan tangshen root. The intestinal motility medicinal composition has the characteristics of obvious medicinal effect, low using cost, no toxic or side effect and the like. After the intestinal motility medicinal composition is used, the phenomena of dying of fish, shrimps and crabs are reduced obviously, and the immune resistance of organisms is improved. After the intestinal motility medicinal composition is used continuously, death caused by severe bottom environment in the middle and later periods of aquaculture can be prevented, the aquaculture yield and success rate are improved, and the economic benefits of farmers are ensured fully. Simultaneously the intestinal motility medicinal composition is a pure Chinese medicinal preparation, has no toxic or side effect and avoids medicinal residues in animal bodies, so the food quality of fish, shrimp and crab products is ensured.
Description
Technical field
The present invention relates to a kind of aquatic animal medication, especially relate to a kind of control fish, shrimp, the sick intestinal motive force pharmaceutical composition of Eriocheir sinensis intestinal.
Background technology
Both at home and abroad the expert studies show that: fish, shrimp, Eriocheir sinensis poor growth, even dead mainly are because its intestinal is subjected to the infringement of various antibacterials, virus and insect pest causes.As escherichia coli, Salmonella, vibrio and pasteurellosis bacillus etc.After fish got digestive tract disease, sick fish was slow in action, does not eat food, and abdominal part expands, the body colour blackening, and seroperitoneum, intestinal wall hyperemia is bronzing; Even a large amount of necrosis of intestinal mucosa come off, and enteral does not have food, has only many flaxen mucus.As untimely treatment, sick fish can die very soon.
Shrimp, the Eriocheir sinensis metenteron of falling ill reddens, and stomach is the most obvious, and the midgut rear portion also reddens or swelling, and it is muddy that rectum (hindgut) becomes, and the expansion of intestinal wall erythrocyte has a large amount of hemocytees to assemble; A little less than sick shrimp torpescence, the body constitution, anorexia, poor growth, the intestinal sky has liquid or yellow pus shape thing, and pigment is many on the carapace.This disease infects very fast, all can cause shrimp, Eriocheir sinensis mortality as untimely prevention or malpractice, causes serious economy loss to the raiser.
Summary of the invention
The present invention mainly is that the medicine that solves symptom in tradition control fish, shrimp, the various intestinals of Eriocheir sinensis is cured the symptoms, not the disease, and prevention effect is relatively poor, and technical problems such as poison of drug is residual are arranged in the animal body.
For solving the problems of the technologies described above, the technical solution used in the present invention is: described intestinal motive force pharmaceutical composition is made by the following components in part by weight proportioning: 10 parts～100 parts of the Radix Pulsatillaes, 10 parts～100 parts of Herba Portulacaes, 20 parts～150 parts of Herba Pogostemoniss, 5 parts～50 parts of Radix et Rhizoma Thalictri, 10 parts～70 parts of Fructus Chebulaes, 5 parts～50 parts of Alumens, 10 parts～100 parts of flower of poplar, 5 parts～60 parts of Rhizoma Bistortaes, 5 parts～50 parts of Radix Codonopsis.
The optimum ratio of said components is: 20 parts～50 parts of the Radix Pulsatillaes, 40 parts～70 parts of Herba Portulacaes, 60 parts～90 parts of Herba Pogostemoniss, 20 parts～50 parts of Radix et Rhizoma Thalictri, 20 parts～50 parts of Fructus Chebulaes, 15 parts～50 parts of Alumens, 30 parts～60 parts of flower of poplar, 20 parts～60 parts of Rhizoma Bistortaes, 20 parts～50 parts of Radix Codonopsis.
The optimal components ratio of said components is: 50 parts of the Radix Pulsatillaes, 50 parts of Herba Portulacaes, 75 parts of Herba Pogostemoniss, 25 parts of Radix et Rhizoma Thalictri, 35 parts of Fructus Chebulaes, 25 parts of Alumens, 50 parts of flower of poplar, 30 parts of Rhizoma Bistortaes, 30 parts of Radix Codonopsis.
The preparation above-mentioned composition can adopt following common process, both the Radix Pulsatillae, Herba Portulacae, Herba Pogostemonis, Radix et Rhizoma Thalictri, Fructus Chebulae, Alumen, flower of poplar, Rhizoma Bistortae, Radix Codonopsis were crushed to 150 orders respectively, after the drying, by proportioning described in the compositions above-mentioned medicinal powder is mixed, can obtain the intestinal motive force pharmaceutical composition.
In component of the present invention: the Radix Pulsatillae, another name: Mao aunt flower, old biddy spend, husband spends; Be distributed in the ground such as Jilin, Liaoning, Hebei of China, have heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, the effect of removing dampness and killing parasites cures mainly pyretic toxicity dysentery, epistaxis, diseases such as internal hemorrhoid with bleeding are on the books in medicine ancient books and records such as Shennong's Herbal, " book on Chinese herbal medicine is looked for the truth ".
Herba Portulacae has heat-clearing and toxic substances removing, and diuretic dries, the blood detumescence of loosing, and the dedusting sterilization, anti-inflammatory analgetic, the hemostasis removing heat from blood cures mainly dysentery, enteritis, diseases such as nephritis.All produce various places, Herba Portulacae China north and south, with all herbal medicine of plant, on the books in the medicine ancient books and records such as Compendium of Material Medica, " Kaibao Bencao ".
The Herba Pogostemonis slightly warm in nature has dispelling summer-heat from superficies of the body, effects such as removing dampness to restore normal function of the stomach, and it is vexed to be used for breast gastral cavity painful abdominal mass, and vomiting is had loose bowels and is waited disease to treat.The Herba Pogostemonis main product is in main product what Sichuan, Jiangsu, Zhejiang, Hunan, Guangdong and other places, and is on the books in medicine ancient books and records such as " Mingyi Bielus ".
Radix et Rhizoma Thalictri has antiinflammatory, analgesia, cooling effect to animal.Radix et Rhizoma Thalictri is distributed in ground such as China Sichuan, Yunnan, Tibet, and is on the books in medicine ancient books and records such as " Yunnan Chinese herbal medicine ".
Fructus Chebulae another name: chebule, scold multitude, scold pears, son with the wind, cure mainly and astringe the lung, astringing intestine to stop diarrhea, the therapeutic method to keep the adverse QI flowing downwards, sore-throat relieving cures mainly chronic dysentery, proctoptosis, the diseases such as phlegmatic cough of breathing with cough.The Fructus Chebulae is distributed in ground such as western part, Yunnan and the west and south, and is on the books in medicine ancient books and records such as " Bencao Tujings ".
Alumen has another name called Alumen, and sour-puckery flavor cold in nature has stronger astriction, and the traditional Chinese medical science thinks that Alumen has the detoxifcation parasite killing, dampness removing to stop itchin, hemostasis antidiarrheal, the effect of heat clearing away expectorant.
Flower of poplar is cold in nature, and effects such as heat-clearing and toxic substances removing, relieving diarrhea with astringents, removing dampness dysentery relieving, strengthening the spleen and nourishing the stomach can be prevented and treated bacillary dysentery and enteritis.Flower of poplar is used as medicine with alabastrum, buddings spring when blooming, and wins staminate inflorescence in batches, and using fresh herb or dry the back and use mainly is distributed in ground such as Liaoning, Hebei, Shanxi.
The Rhizoma Bistortae another name: Herba Salviae Chinensis, Rhizoma Paridis, the cold nature heat-clearing and toxic substances removing, removing heat from blood is used for disease treatments such as enteritis, dysentery, hepatitis, bleeding hemorrhoids.Ground such as Rhizoma Bistortae main product North China, northwest and Shandong, Jiangsu, Hubei, on the books in medicine ancient books and records such as " Bencao Tujings ".
The Radix Codonopsis another name: Shangdang Radix Ginseng, Radix Saposhnikoviae Radix Codonopsis, HUANGSHEN, the root for campanulaceae plant Radix Codonopsis, plain flower Radix Codonopsis, radix codonpsis tangshen has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Radix Codonopsis is distributed in ground such as Shanxi, Hubei, Sichuan, and its beginning sees Qing Dynasty's " Bencao Congxin ", and is also on the books the Pharmacopoeia of the People's Republic of China 2010 editions.
Distinguish that according to the traditional Chinese medical science disease executes the improvement opinion, accumulate large intestine in the damp and hot malicious heresy, disease such as that the enteritis disease shows as is damp and hot, pyretic toxicity, insufficiency of the spleen, deficiency of vital energy.The present invention is by selected drug component, and reasonable compatibility is brought into play the synergism of each component, has following effect:
1, improves fish, shrimp, Eriocheir sinensis intestinal microecology environment and keep colony balance, increase intestinal beneficial bacterium group quantity, prevent and treat diseases such as bacillary and viral enteritis.
2, promote the secretion of various digestive enzyme, improve appetite and the digestibility of fish, shrimp, Eriocheir sinensis, reduce feed coefficient.
3, suppress the growth of pathogenic bacteria breeding, assist to eliminate toxin, strengthen immunity and the premunition of fish, shrimp, Eriocheir sinensis.
4, improve fish, shrimp, Eriocheir sinensis gastrointestinal function, reduce pathogen quantity in the feces, reduce harmful substance contents in the water.
5, provide nutrient substance such as protein, essential amino acids and vitamin for fish, shrimp, Eriocheir sinensis.
It is remarkable that the present invention has drug effect, and use cost is low, and characteristics such as have no side effect.Steal dead phenomenon after fish, shrimp, Eriocheir sinensis are used and obviously reduce, the immunity of organism resistivity improves.Continue to use, can prevent to culture the death that middle and late stage causes because bottom environment is abominable, increase cultured output and success rate, fully guaranteed raiser's economic interests.Simultaneously because the present invention is pure Chinese medicinal preparation, without any side effects, can not form drug residue in animal body, therefore guaranteed the food quality of fish, shrimp, Eriocheir sinensis series products.
The specific embodiment
Below by embodiment, technical scheme of the present invention is further described in detail.
Embodiment 1: the Radix Pulsatillae, Herba Portulacae, Herba Pogostemonis, Radix et Rhizoma Thalictri, Fructus Chebulae, Alumen, flower of poplar, Rhizoma Bistortae, Radix Codonopsis are crushed to 150 orders respectively, after the drying, get (1 kilogram every part of 10 parts of the Radix Pulsatillae, down with), 100 parts of Herba Portulacaes, 150 parts of Herba Pogostemoniss, 50 parts of Radix et Rhizoma Thalictri, 70 parts of Fructus Chebulaes, 50 parts of Alumens, 10 parts of flower of poplar, 5 parts of Rhizoma Bistortaes, 50 parts of mixing of Radix Codonopsis, can obtain the present composition.
Embodiment 2: the Radix Pulsatillae, Herba Portulacae, Herba Pogostemonis, Radix et Rhizoma Thalictri, Fructus Chebulae, Alumen, flower of poplar, Rhizoma Bistortae, Radix Codonopsis are crushed to 150 orders respectively, after the drying, get 100 parts of the Radix Pulsatillaes, 10 parts of Herba Portulacaes, 20 parts of Herba Pogostemoniss, 5 parts of Radix et Rhizoma Thalictri, 10 parts of Fructus Chebulaes, 5 parts of Alumens, 100 parts of flower of poplar, 60 parts of Rhizoma Bistortaes, 5 parts of mixing of Radix Codonopsis, can obtain the present composition.
Embodiment 3: the Radix Pulsatillae, Herba Portulacae, Herba Pogostemonis, Radix et Rhizoma Thalictri, Fructus Chebulae, Alumen, flower of poplar, Rhizoma Bistortae, Radix Codonopsis are crushed to 150 orders respectively, after the drying, get 50 parts of the Radix Pulsatillaes, 40 parts of Herba Portulacaes, 60 parts of Herba Pogostemoniss, 20 parts of Radix et Rhizoma Thalictri, 50 parts of Fructus Chebulaes, 15 parts of Alumens, 60 parts of flower of poplar, 20 parts of Rhizoma Bistortaes, 20 parts of mixing of Radix Codonopsis, can obtain the present composition.
Embodiment 4: the Radix Pulsatillae, Herba Portulacae, Herba Pogostemonis, Radix et Rhizoma Thalictri, Fructus Chebulae, Alumen, flower of poplar, Rhizoma Bistortae, Radix Codonopsis are crushed to 150 orders respectively, after the drying, get 20 parts of the Radix Pulsatillaes, 70 parts of Herba Portulacaes, 90 parts of Herba Pogostemoniss, 50 parts of Radix et Rhizoma Thalictri, 20 parts of Fructus Chebulaes, 50 parts of Alumens, 30 parts of flower of poplar, 60 parts of Rhizoma Bistortaes, 50 parts of mixing of Radix Codonopsis, can obtain the present composition.
Embodiment 5: the Radix Pulsatillae, Herba Portulacae, Herba Pogostemonis, Radix et Rhizoma Thalictri, Fructus Chebulae, Alumen, flower of poplar, Rhizoma Bistortae, Radix Codonopsis are crushed to 150 orders respectively, after the drying, get 50 parts of the Radix Pulsatillaes, 50 parts of Herba Portulacaes, 75 parts of Herba Pogostemoniss, 25 parts of Radix et Rhizoma Thalictri, 35 parts of Fructus Chebulaes, 25 parts of Alumens, 50 parts of flower of poplar, 30 parts of Rhizoma Bistortaes, 30 parts of mixing of Radix Codonopsis, can obtain the present composition.
Embodiment 6: the Radix Pulsatillae, Herba Portulacae, Herba Pogostemonis, Radix et Rhizoma Thalictri, Fructus Chebulae, Alumen, flower of poplar, Rhizoma Bistortae, Radix Codonopsis are crushed to 150 orders respectively, after the drying, get 70 parts of the Radix Pulsatillaes, 80 parts of Herba Portulacaes, 120 parts of Herba Pogostemoniss, 40 parts of Radix et Rhizoma Thalictri, 50 parts of Fructus Chebulaes, 40 parts of Alumens, 60 parts of flower of poplar, 45 parts of Rhizoma Bistortaes, 30 parts of mixing of Radix Codonopsis, can obtain the present composition.
Below further verify beneficial effect of the present invention by the curative effect of medication contrast test.
Experimental example 1: select to have A, the B fishpond of enteritis disease, A fishpond area is that 3 mu, sick fish quantity are about about 1050 tails; The B fishpond is 3.5 mu, and sick fish quantity is about about 1100 tails.
The A pond is test tank, and the embodiment of the invention 4 or 5 or 6 is made pharmaceutical composition, with this pharmaceutical composition and the abundant mixing of fish meal, makes bait feeding in the ratio of feedstuff gross weight 1%, once a day, throws something and feeds continuously 5～6 days.
The B pond is the contrast pond, and per 50 kilograms of feedstuffs add furazolidone 10～15 grams, make bait feeding, once a day, throw something and feed continuously 5～6 days.Its therapeutic outcome is as shown in table 1:
Table 1: fishpond dispensing contrast test
Test shows: test tank was used the present invention after 24 hours, and sick fish symptom improves, and mortality rate is effectively controlled, and mortality rate only is 1%.Though the sick fish symptom in contrast pond makes moderate progress, mortality rate is still up to 2%.And culturing middle and late stage, the inventor is by continuing to use pharmaceutical composition of the present invention to show: the present invention can also increase cultured output and survival rate.
Experimental example 2: select to suffer from A, two mouthfuls of Penaeus vannamei shrimps of B pond of black gill disease, A shrimp pool area is 24m
2, shrimp quantity is about 5000 tails; B shrimp pond is 24m
2Mu, shrimp quantity is about 5000 tails.
The A pond is test tank, and the embodiment of the invention 3 or 4 or 5 is made pharmaceutical composition, makes every mu of rice of pharmaceutical composition 150g the morning on daytime, evenly splashes in A shrimp pond, is used in conjunction 2 days.
The morning on daytime is used the erythromycin full pool spilling head for the contrast pond in the B pond, and erythromycin concentration is 1 * 10
-6, be used in conjunction 3 days; The erythromycin medicine of throwing something and feeding was simultaneously raised (content of dispersion is 0.05%) 3 days, and its therapeutic outcome is as shown in table 1:
Table 2: shrimp pond dispensing result of the test.
Conclusion (of pressure testing): after test tank was used the present invention, sick shrimp symptom improved, and mortality rate is effectively controlled, and mortality rate only is 0.5%.Though the sick shrimp symptom in contrast pond also improves, owing to be in antibiotic, the shrimp body drug residue to be arranged.And life-time service has the risk that strengthens bacterial drug resistance.
Claims (3)
1. intestinal motive force compositions is characterized in that described pharmaceutical composition made by the following components in part by weight proportioning: 10 parts～100 parts of the Radix Pulsatillaes, 10 parts～100 parts of Herba Portulacaes, 20 parts～150 parts of Herba Pogostemoniss, 5 parts～50 parts of Radix et Rhizoma Thalictri, 10 parts～70 parts of Fructus Chebulaes, 5 parts～50 parts of Alumens, 10 parts～100 parts of flower of poplar, 5 parts～60 parts of Rhizoma Bistortaes, 5 parts～50 parts of Radix Codonopsis.
2. intestinal motive force pharmaceutical composition according to claim 1 is characterized in that the proportioning of described pharmaceutical composition is: 20 parts～50 parts of the Radix Pulsatillaes, 40 parts～70 parts of Herba Portulacaes, 60 parts～90 parts of Herba Pogostemoniss, 20 parts～50 parts of Radix et Rhizoma Thalictri, 20 parts～50 parts of Fructus Chebulaes, 15 parts～50 parts of Alumens, 30 parts～60 parts of flower of poplar, 20 parts～60 parts of Rhizoma Bistortaes, 20 parts～50 parts of Radix Codonopsis.
3. intestinal motive force pharmaceutical composition according to claim 2 is characterized in that the proportioning of described pharmaceutical composition is: 50 parts of the Radix Pulsatillaes, 50 parts of Herba Portulacaes, 75 parts of Herba Pogostemoniss, 25 parts of Radix et Rhizoma Thalictri, 35 parts of Fructus Chebulaes, 25 parts of Alumens, 50 parts of flower of poplar, 30 parts of Rhizoma Bistortaes, 30 parts of Radix Codonopsis.
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| CN 201010539913 CN102138984B (en) | 2010-10-31 | 2010-10-31 | Intestinal motility medicinal composition |
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| CN 201010539913 CN102138984B (en) | 2010-10-31 | 2010-10-31 | Intestinal motility medicinal composition |
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| CN102138984B true CN102138984B (en) | 2013-09-04 |
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| CN112807348B (en) * | 2021-01-07 | 2023-10-20 | 华南农业大学 | Disease-resistant and growth-promoting traditional Chinese medicine compound, and preparation and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816725A (en) * | 2009-11-16 | 2010-09-01 | 天津瑞贝特科技发展有限公司 | Effervescent traditional Chinese medicine composition having intestine-astringing and dysentery-relieving function and preparation method thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816725A (en) * | 2009-11-16 | 2010-09-01 | 天津瑞贝特科技发展有限公司 | Effervescent traditional Chinese medicine composition having intestine-astringing and dysentery-relieving function and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 《常见兔病的中草药疗法》;陈长佑;《农机具之友》;19951231;第×卷(第3期);38－39 * |
| 《常见兔病的中草药疗法》;陈长佑;《农机具之友》;19951231;第×卷(第3期);电子出版页 * |
| 陈长佑.《常见兔病的中草药疗法》.《农机具之友》.1995,第×卷(第3期),38－39. |
| 陈长佑.《常见兔病的中草药疗法》.《农机具之友》.1995,第×卷(第3期),电子出版页. |
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