CN102133226A - Acid-base neutralizer for protecting human bodies from being burnt by chemical matters - Google Patents
Acid-base neutralizer for protecting human bodies from being burnt by chemical matters Download PDFInfo
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- CN102133226A CN102133226A CN2011100652482A CN201110065248A CN102133226A CN 102133226 A CN102133226 A CN 102133226A CN 2011100652482 A CN2011100652482 A CN 2011100652482A CN 201110065248 A CN201110065248 A CN 201110065248A CN 102133226 A CN102133226 A CN 102133226A
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- acid
- metal salt
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- human bodies
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- 239000000126 substance Substances 0.000 title claims abstract description 16
- 150000003839 salts Chemical class 0.000 claims abstract description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 29
- 229910052751 metal Inorganic materials 0.000 claims abstract description 27
- 239000002184 metal Substances 0.000 claims abstract description 27
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 17
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 17
- 239000007788 liquid Substances 0.000 claims abstract description 15
- 238000006386 neutralization reaction Methods 0.000 claims abstract description 15
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 21
- 239000002738 chelating agent Substances 0.000 claims description 11
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims description 8
- 239000004327 boric acid Substances 0.000 claims description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 7
- 239000008103 glucose Substances 0.000 claims description 7
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 claims description 6
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 5
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 5
- 229930195725 Mannitol Natural products 0.000 claims description 5
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 5
- 239000000594 mannitol Substances 0.000 claims description 5
- 235000010355 mannitol Nutrition 0.000 claims description 5
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 claims description 4
- 229930006000 Sucrose Natural products 0.000 claims description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 4
- 239000000174 gluconic acid Substances 0.000 claims description 4
- 235000012208 gluconic acid Nutrition 0.000 claims description 4
- 239000005720 sucrose Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 3
- 229940059574 pentaerithrityl Drugs 0.000 claims description 3
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 claims description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 2
- 229910052782 aluminium Inorganic materials 0.000 claims description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 229910052791 calcium Inorganic materials 0.000 claims description 2
- 229910052700 potassium Inorganic materials 0.000 claims description 2
- 239000011591 potassium Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 12
- 230000001105 regulatory effect Effects 0.000 abstract description 4
- 238000006243 chemical reaction Methods 0.000 abstract description 3
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008139 complexing agent Substances 0.000 abstract 1
- 230000007797 corrosion Effects 0.000 abstract 1
- 238000005260 corrosion Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000003513 alkali Substances 0.000 description 12
- 239000002253 acid Substances 0.000 description 11
- 230000003204 osmotic effect Effects 0.000 description 11
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 8
- 238000004090 dissolution Methods 0.000 description 7
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 6
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 239000002585 base Substances 0.000 description 5
- 239000001103 potassium chloride Substances 0.000 description 4
- 235000011164 potassium chloride Nutrition 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000005202 decontamination Methods 0.000 description 3
- 230000003588 decontaminative effect Effects 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 239000001110 calcium chloride Substances 0.000 description 2
- 229910001628 calcium chloride Inorganic materials 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 230000008595 infiltration Effects 0.000 description 2
- 238000001764 infiltration Methods 0.000 description 2
- 208000037805 labour Diseases 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 208000009043 Chemical Burns Diseases 0.000 description 1
- 208000018380 Chemical injury Diseases 0.000 description 1
- 208000013935 Electric injury Diseases 0.000 description 1
- 206010020852 Hypertonia Diseases 0.000 description 1
- 229910021578 Iron(III) chloride Inorganic materials 0.000 description 1
- 241000972155 Moschus Species 0.000 description 1
- 241000972673 Phellodendron amurense Species 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- DIZPMCHEQGEION-UHFFFAOYSA-H aluminium sulfate (anhydrous) Chemical compound [Al+3].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O DIZPMCHEQGEION-UHFFFAOYSA-H 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 239000013064 chemical raw material Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- UIIMBOGNXHQVGW-UHFFFAOYSA-N sodium;hydron;carbonate Chemical compound [Na+].OC(O)=O UIIMBOGNXHQVGW-UHFFFAOYSA-N 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
Abstract
The invention relates to a human body decontaminating liquid for the field of industrial safety prevention, in particular to an acid-base neutralizer for preventing human bodies from being burnt by chemical matters. The acid-base neutralizer comprises a complexing agent, sugar, polyethylene glycol, monovalent metal salt, polyvalent metal salt, polyhydric alcohol, a pH regulating agent and water. With the principle of realizing neutralization by utilizing a reaction of the polyvalent metal salt and strong-alkalinity matters, the acid-base neutralizer achieves the purpose of protection, and when the human bodies are burnt and corroded by the chemical matters, especially the strong-alkalinity matters, the acid-base neutralizer has a better restoration effect on the burnt and corroded positions of the human bodies, has stable performance and convenience for storage and management and is especially suitable for large-range emergent protection rescue application after large and medium-size accidents happen, thereby lightening the burn and corrosion of the chemical matters for the human bodies.
Description
One, technical field
The present invention relates to a kind of human body decontamination solution that is used for industrial safety protection field, particularly a kind ofly be used to protect the acid-base neutralization liquid that human body is burnt by chemical substance.
Two, background technology
In modern industry is produced, particularly use the occasion of various strong acid alkaline matters, strong acid alkaline matter accidental release is often arranged and produce the accident that human body is burnt and take place.For avoiding or erosion when alleviating the strong acid alkaline matter human body being burnt as far as possible, generally adopt neutrality such as water, normal saline or suds or weakly alkaline solution carries out decontamination and emergence control is handled, tool has certain effect.But under emergency owing to be difficult to the kind in time distinguish corrosive substance, and traditional decontamination solution kind single, can't suit the remedy to the case, realize suing and labouring due to wound.Can only clean surface as water, and can not catch the chemical substance that enters the human body skin internal layer, make decontaminating effect restricted greatly, incured loss through delay the best opportunity of suing and labouring in a way, even the sequela that can cause human body to burn.Chemical burn medicine of record in South-Center University For Nationalities chemistry and material science institute in the December, 2006 " the Experiment of Inorganic Chemstry teaching materials " of writing and for example: 5% sodium bicarbonate, 1% boric acid, 2% acetic acid, ammonia, 2% copper-bath.Though it is feasible in theory, the decontaminating effect in the practical application is also not obvious, to the burn essentially no pharmacological curative effect of reparation at position of human body.For overcoming the deficiency of existing industrial safety preventive means, Chinese patent application 200610086919.2 discloses " a kind of pharmaceutical composition for the treatment of empyrosis and preparation method thereof ", the main component of the pharmaceutical composition of its record is: Radix Et Rhizoma Rhei, phellodendron bark, Cortex ulmi pumilae, Radix Scutellariae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi) can also add a small amount of Borneolum Syntheticum and Moschus.Can be used for treating burn, electric injury, oil scald, soda acid burn and traumatic injury of skin etc., good effect, instant effect and cure rate height.But it only belongs to the medicine after the wound, is not suitable for industrial safety protection the emergent of the scene of the accident and sues and labours.In sum, how to overcome the deficiencies in the prior art and become one of great difficult problem that current industrial safety protection field needs to be resolved hurrily.
Three, summary of the invention
The objective of the invention is provides a kind of acid-base neutralization liquid that human body is burnt by chemical substance that is used to protect for overcoming the deficiencies in the prior art, when human body be subjected to chemical substance particularly the strong acid alkaline matter burn when corroding, the present invention can act on the human body attack sites of burning, to alleviate the burn erosion of chemical substance to human body.
A kind of being used to that proposes according to the present invention protected the acid-base neutralization liquid that human body is burnt by chemical substance, it is characterized in that comprising chelating agent, sugar, Polyethylene Glycol, univalent metal salt, multivalent metal salt, polyhydric alcohol, PH regulator and water.The present invention's component by weight ratio is: chelating agent 0.5-7%, sugared 0.2-3%, Polyethylene Glycol 0.2-2%, univalent metal salt 0.1-10%, multivalent metal salt 0.5-20%, polyhydric alcohol 0.1-3.5%, PH regulator 0.1-10%, all the other are water, are supplemented to 100%.The further preferred version of the present invention, component by weight ratio is: chelating agent 2.33-7%, sugared 0.5-2.5%, Polyethylene Glycol 0.5-1.2%, univalent metal salt 0.8-8%, multivalent metal salt 0.9-16%, polyhydric alcohol 0.3-3.5%, PH regulator 0.25-6%, all the other are water, are supplemented to 100%.Chelating agent in the proportioning component of the present invention is one or more in disodium EDTA, gluconic acid or the boric acid, in neutralizer of the present invention, play guarantee multivalent metal salt in and the time rapid-action effect takes place; Sugar in the proportioning component of the present invention is one or both the mixture in glucose or the sucrose, plays the suction moisture-keeping function in neutralizer of the present invention; Polyethylene Glycol in the proportioning component of the present invention plays the effect of regulating viscosity in of the present invention; Univalent metal salt in the proportioning component of the present invention is the water soluble salt of potassium or sodium, in neutralizer of the present invention, play the effect of the osmotic pressure of regulating product, suitable osmotic pressure can promote oozing out of human body fluid, thereby avoids the infiltration to the human body dermal tissue of acid or alkali; Multivalent metal salt in the proportioning component of the present invention is one or more in the water soluble salt of calcium, aluminum or ferrum, plays in neutralizer of the present invention with acid or alkali reaction and reduces acid or alkaline effect rapidly; Polyhydric alcohol in the proportioning component of the present invention is one or more in tetramethylolmethane, mannitol or the glycerol, plays water retention in neutralizer of the present invention, prevents that skin from coming to harm because of dehydration; PH regulator in the proportioning component of the present invention is a citric acid, and the pH value that citric acid can be regulated neutralizer finished product of the present invention reaches 6-8.With constituent water dissolution in the said ratio component, can make neutralizer finished product of the present invention through abundant mixing.
The present invention compared with prior art its remarkable advantage is: first, the present invention can realize that by multivalent metal salt and strong acid alkali substance reaction neutral principle reaches the protection purpose, the osmotic pressure that the present invention acts on human body will exceed much than human body normal plasma osmotic pressure, this hypertonicity can be the chemical substance that corrodes human body from organizing interior extraction, alleviate the strong acid alkaline matter and corrode, the human body attack sites of being burnt is had repairing effect preferably to the infiltration of tissue.The second, the not only emergent protection of the present invention is sued and laboured effective, and preparation cost is low, is specially adapted to the emergent on a large scale protection after the big-and-middle-sized accident generation is sued and laboured.The 3rd, backlog control is convenient in stable performance of the present invention.The present invention be applicable to chemical substance in the industrial safety protection field to human body the burn emergent protection of accident sue and labour.
Four, the specific embodiment
The present invention is described in further detail below in conjunction with embodiment.
A kind of being used to that the present invention proposes protected the acid-base neutralization liquid that human body is burnt by chemical substance, comprises chelating agent, sugar, Polyethylene Glycol, univalent metal salt, multivalent metal salt, polyhydric alcohol, PH regulator and water; Component by weight ratio is: chelating agent 0.5-7%, sugared 0.2-3%, Polyethylene Glycol 0.2-2%, univalent metal salt 0.1-10%, multivalent metal salt 0.5-20%, polyhydric alcohol 0.1-3.5%, PH regulator 0.1-10%, all the other are water, are supplemented to 100%; The preferred version of component by weight ratio is: chelating agent 2.33-7%, sugared 0.5-2.5%, Polyethylene Glycol 0.5-1.2%, univalent metal salt 0.8-8%, multivalent metal salt 0.9-16%, polyhydric alcohol 0.3-3.5%, PH regulator 0.25-6%, all the other are water, are supplemented to 100%.All raw materials that the present invention adopts are commercially available chemical raw material, meet the Pharmacopoeia of People's Republic of China standard.In following examples, represent the neutralising capacity of neutralizer of the present invention with sour counteragent and alkali counteragent.Be that the alkali counteragent is: in and 1 ml concn be the sodium hydroxide of 1 mol equals 10 used neutralizers to PH volume number; The acid counteragent is: in and 1 ml concn be the hydrochloric acid of 1 mol equals 5 used neutralizers to PH volume number.The present invention with make the alkali counteragent 10-35 of neutralizer finished product, sour counteragent 10-35, osmotic pressure is certified products greater than 800 kPa and pH value 6-8.
Embodiment 1:The present invention's component by weight ratio is: aluminum chloride 3%, boric acid 1%, disodium EDTA 3%, sodium chloride 1.5%, Polyethylene Glycol 1.2%, glucose 1.5%, glycerol 2.5%, citric acid 0.5%, water 85.8%; With each component water dissolution, promptly make the neutralizer finished product after fully mixing.Record alkali counteragent 35, sour counteragent 30, osmotic pressure 1200 kPa, the pH value 7.5 of its finished product.
Embodiment 2:The present invention's component by weight ratio is: aluminum chloride 8%, calcium chloride 8%, boric acid 0.5%, disodium EDTA 5%, sodium chloride 7%, Polyethylene Glycol 0.5%, sucrose 0.5%, tetramethylolmethane 0.3%, citric acid 5%, water 65.2%; With each component water dissolution, promptly make the neutralizer finished product after fully mixing.Record alkali counteragent 21, sour counteragent 26, osmotic pressure 2400 kPa, the pH value 6.5 of its finished product.
Embodiment 3: the present invention's component by weight ratio is: aluminum sulfate 3%, gluconic acid 0.8%, boric acid 4%, potassium chloride 1%, Polyethylene Glycol 0.5%, glucose 1%, sucrose 0.5%, glycerol 0.5%, citric acid 1%, water 87.7%; With each component water dissolution, promptly make the neutralizer finished product after fully mixing.Record alkali counteragent 37, sour counteragent 31, osmotic pressure 1600 kPa, the pH value 7.3 of its finished product.
Embodiment 4:The present invention's component by weight ratio is: disodium EDTA 2%, aluminum chloride 0.9%, glucose 2.5%, boric acid 0.33%, potassium chloride 0.8%, Polyethylene Glycol 0.8%, mannitol 1%, citric acid 0.25%, glycerol 1.7%, water 89.72%; With each component water dissolution, promptly make the neutralizer finished product after fully mixing.。Record alkali counteragent 27, sour counteragent 30, osmotic pressure 1200 kPa, the pH value 6.5 of its finished product.
Embodiment 5:The present invention's component by weight ratio is: gluconic acid 5%, calcium chloride 10%, glucose 1%, boric acid 2%, potassium chloride 0.8%, Polyethylene Glycol 0.5%, mannitol 1%, citric acid 6%, glycerol 2%, water 71.7%; With each component water dissolution, promptly make the neutralizer finished product after fully mixing.Record alkali counteragent 25, sour counteragent 22, osmotic pressure 1500 kPa, the pH value 6.5 of its finished product.
Embodiment 6:The present invention's component by weight ratio is: ethylenediaminetetraacetic acid 5%, ferric chloride 5%, glucose 1.5%, potassium chloride 8%, Polyethylene Glycol 1%, mannitol 1%, citric acid 3%, glycerol 2.5%, water 73%; With each component water dissolution, promptly make the neutralizer finished product after fully mixing.Record alkali counteragent 28, sour counteragent 25, osmotic pressure 2200 kPa, the pH value 7.8 of its finished product.
Claims (9)
1. one kind is used to protect the acid-base neutralization liquid that human body is burnt by chemical substance, it is characterized in that comprising chelating agent, sugar, Polyethylene Glycol, univalent metal salt, multivalent metal salt, polyhydric alcohol, PH regulator and water.
2. acid-base neutralization liquid according to claim 1, the composition by weight that it is characterized in that proportioning is: chelating agent 0.5-7%, sugared 0.2-3%, Polyethylene Glycol 0.2-2%, univalent metal salt 0.1-10%, multivalent metal salt 0.5-20%, polyhydric alcohol 0.1-3.5%, PH regulator 0.1-10%, all the other are water, are supplemented to 100%.
3. acid-base neutralization liquid according to claim 1, the composition by weight that it is characterized in that proportioning is: chelating agent 2.33-7%, sugared 0.5-2.5%, Polyethylene Glycol 0.5-1.2%, univalent metal salt 0.8-8%, multivalent metal salt 0.9-16%, polyhydric alcohol 0.3-3.5%, PH regulator 0.25-6%, all the other are water, are supplemented to 100%.
4. according to claim 1,2 or 3 described acid-base neutralization liquid, it is characterized in that chelating agent is one or more in disodium EDTA, gluconic acid or the boric acid.
5. according to claim 1,2 or 3 described acid-base neutralization liquid, it is characterized in that sugar is one or both in glucose or the sucrose.
6. according to claim 1,2 or 3 described acid-base neutralization liquid, it is characterized in that univalent metal salt is the water soluble salt of potassium or sodium.
7. according to claim 1,2 or 3 described acid-base neutralization liquid, it is characterized in that multivalent metal salt is one or more in the water soluble salt of calcium, aluminum or ferrum.
8. according to claim 1,2 or 3 described acid-base neutralization liquid, it is characterized in that polyhydric alcohol is one or more in tetramethylolmethane, mannitol or the glycerol.
9. according to claim 1,2 or 3 described acid-base neutralization liquid, it is characterized in that the PH regulator is a citric acid.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100652482A CN102133226A (en) | 2011-03-18 | 2011-03-18 | Acid-base neutralizer for protecting human bodies from being burnt by chemical matters |
| PCT/CN2011/074303 WO2012126198A1 (en) | 2011-03-18 | 2011-05-19 | Acid-base neutralizing solution for chemical burning protection |
| CN2012100694297A CN102764268A (en) | 2011-03-18 | 2012-03-16 | Acid-base neutralization solution for protecting human body from being burned by chemical substances |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100652482A CN102133226A (en) | 2011-03-18 | 2011-03-18 | Acid-base neutralizer for protecting human bodies from being burnt by chemical matters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102133226A true CN102133226A (en) | 2011-07-27 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011100652482A Pending CN102133226A (en) | 2011-03-18 | 2011-03-18 | Acid-base neutralizer for protecting human bodies from being burnt by chemical matters |
| CN2012100694297A Pending CN102764268A (en) | 2011-03-18 | 2012-03-16 | Acid-base neutralization solution for protecting human body from being burned by chemical substances |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012100694297A Pending CN102764268A (en) | 2011-03-18 | 2012-03-16 | Acid-base neutralization solution for protecting human body from being burned by chemical substances |
Country Status (2)
| Country | Link |
|---|---|
| CN (2) | CN102133226A (en) |
| WO (1) | WO2012126198A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106214686A (en) * | 2016-07-01 | 2016-12-14 | 吉林大学珠海学院 | A kind of bionical tissue fluid with resist chemical |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6527872B1 (en) * | 1999-07-28 | 2003-03-04 | Steris Inc. | Environmentally friendly peracetic acid decontamination formula with increased performance and chemical stability |
| CN1919209A (en) * | 2006-07-10 | 2007-02-28 | 江西3L医用制品集团有限公司 | Pharmaceutical composition for healing skin wound |
| CN101698102A (en) * | 2009-05-13 | 2010-04-28 | 朱玛华 | Ultra-potent composite for decontaminating hazardous chemical substances |
| CN101732341A (en) * | 2009-12-21 | 2010-06-16 | 中国人民解放军海军医学研究所 | Washing-disinfecting liquid and disinfecting-washing bag thereof for radioactive skin contamination |
-
2011
- 2011-03-18 CN CN2011100652482A patent/CN102133226A/en active Pending
- 2011-05-19 WO PCT/CN2011/074303 patent/WO2012126198A1/en active Application Filing
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2012
- 2012-03-16 CN CN2012100694297A patent/CN102764268A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN102764268A (en) | 2012-11-07 |
| WO2012126198A1 (en) | 2012-09-27 |
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Application publication date: 20110727 |