CN102125677B - 治疗急性胆囊炎的中药制剂 - Google Patents
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Abstract
本发明属于中药制剂领域，涉及一种治疗急性胆囊炎的中药制剂，由如下重量份数的中药原料制成：柴胡4份、白芍6份、川楝子6份、姜黄3份、虎杖4份、丹参4份、槟榔3份、郁金4份和枳实6份。具有疏肝利胆、行气止痛的功效，本发明是在中医辨证施治的基础上结合现代科研成果研制而成的，本发明适用于治疗急性胆囊炎，它具有见效快、治愈率高、不易复发、无副作用等特点。
Description
技术领域
本发明属于中药制剂领域，特别涉及一种治疗急性胆囊炎的中药制剂。
背景技术
急性胆囊炎是胆囊受到致病因素损害而引起的急性炎症性疾病，是外科常见的急腹症之一，一般40～60岁的病人多见，女性发病率高。临床多见右上腹疼痛，常伴有恶心呕吐，吐后腹痛不减轻，偶见黄疸，属中医学的胁痛之范畴，而本病的主要病机是肝胆气机不畅、气血运行不利。“胆”为“中清之府”，若长期的肝失疏泄、湿热不化，胆液滞留，久则煎熬便可形成胆结石，故在临床中，疏肝利胆、行气止痛为主要治疗大法，故发明一种既安全又有效的中药制剂意义重大。
发明内容
本发明是在传统的中医辨证施治的基础上结合多年临床实践研制而成的治疗急性胆囊炎的中药制剂，本发明治疗急性胆囊炎具有疗效可靠、见效快、无副作用等特点。
本发明一种治疗急性胆囊炎的中药制剂，其特征在于各原料的重量份数为：柴胡4份、白芍6份、川楝子6份、姜黄3份、虎杖4份、丹参4份、槟榔3份、郁金4份和枳实6份。
制备方法是按上述重量份数称取原料，洗净去杂，加水浸泡2小时，置多功能提取罐中加水煎煮2次，第一次加药材总量10倍的水，煎煮2小时取煎液，第二次加总药材7倍的水煎煮1小时，取2次煎液混合过滤，热封袋中，包装，每袋200ml，口服，一次一袋，每日2次，7天为一疗程。
药理分析：
柴胡 疏散退热、疏肝解郁、升阳举陷。本品味辛苦，芳香疏泄，少阳半表半里之邪，是治疗邪在少阳之要药，本品能条达肝气、调经止痛，是治疗肝郁气滞、胸胁疼痛的常用药。
白芍 养血调经、平肝止痛、敛阴止汗，临床常用本品治疗血虚阴虚、肝阴不足、肝气不舒引起的胸胁疼痛，有养血调经、缓急疼痛之功效。
川楝子 行气止痛、杀虫疗癣，本品苦寒降泄，能清肝火泄郁热，行气止痛。
姜黄 活血行气、通经止痛，本品辛散温通，能活血行气，使瘀散滞通而痛解。
虎杖 疏肝利胆、清热解毒、活血祛瘀，本品苦寒善泄中焦瘀滞，降泻肝胆湿热、利胆退黄，又是清热利湿之良药。
槟榔 杀虫消积、行气利水，本品功善行胃肠之气，消积导滞，能降膈肌之气。
丹参 活血调经、凉血消痛、安神，本品是活血化瘀之要药，广泛应用于各种瘀血之证。
郁金 活血行气止痛、解郁清心、利胆退黄、凉血，本品味辛、能行能散，又能活血解郁，故常用于气滞血瘀之胸胁胀痛之病，本品能入肝胆之经，能清肝胆湿热。
枳实 破气消痞、化痰消积，本品能行气化积、除满而止痛，临床上常用于胸胁痞满之症。
本发明的优点在于所使用的中草药符合中华人民共和国药典规定，药物安全可靠，主要遵循中医君臣佐使的配方原则，用柴胡、白芍、姜黄为君，川楝子、虎杖为臣，槟榔、丹参为佐药，郁金、枳实为使药，诸药相合，共具有疏肝利胆、行气止痛的功效，治疗急性胆囊炎具有疗效可靠、无毒副作用、见效快、不易复发等优点。
疗效判断：
痊愈：右上腹疼痛、恶心呕吐等症状完全消失；查体右上腹无压痛，未触及胆囊一墨菲氏征阴性；B超检查胆囊正常，收缩良好。
好转：右上腹疼痛明显减轻，偶有恶心，但无呕吐、口苦，查体右上腹轻压痛，有时可触及重大的胆囊，博阿斯氏征阴性；白细胞计数及中性粒细胞正常；B超检查胆囊略大。
无效：全身症状无改善。
治疗结果：治疗急性胆囊炎60例。患者服用实施例汤剂每日早晚各一次，每次一袋，七天为一个疗程。连服3个疗程观察疗效，痊愈50例，占83％，好转4例，占7％，无效6例，占10％，总有效率达90％。经3个疗程治疗后，病人无任何不良反应，三大常规及肝胃功能检测未发现异常。
病例1：患者刘某某，男，50岁，患急性胆囊炎，饭后突感右上腹胀痛，伴向右肩背放射，恶心呕吐，口服本发明药物3天后症状大减，10天后症状消失，B超、血常规等检查一切正常，随访半年无复发。
病例2：患者张某某，男，30岁，患急性胆囊炎，口服本发明药物12天，症状完全消失，各项检查均正常，随访1年未复发。
病例3：患者谢某某，男，55岁，患急性胆囊炎，口服本发明药物12天痊愈。
具体实施方式
实施例：
柴胡4份、白芍6份、川楝子6份、姜黄3份、虎杖4份、丹参4份、槟榔3份、郁金4份和枳实6份。
制备方法是按上述重量份数称取原料，洗净去杂，加水浸泡2小时，置多功能提取罐中加水煎煮2次，第一次加药材总量10倍的水，煎煮2小时取煎液，第二次加总药材7倍的水煎煮1小时，取2次煎液混合过滤，热封袋中，包装，每袋200ml，口服，一次一袋，每日2次，7天为一疗程。
Claims (1)
1.一种治疗急性胆囊炎的中药制剂，其特征在于由如下重量份数的中药原料制成：柴胡4份、白芍6份、川楝子6份、姜黄3份、虎杖4份、丹参4份、槟榔3份、郁金4份和枳实6份。
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1615916A (zh) * | 2003-11-12 | 2005-05-18 | 郎伟君 | 一种治疗胆囊炎的药 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1615916A (zh) * | 2003-11-12 | 2005-05-18 | 郎伟君 | 一种治疗胆囊炎的药 |
Non-Patent Citations (6)
| Title |
|---|
| 李双贵 |
| 李双贵;等.自拟疏肝利胆汤治疗慢性胆囊炎142例.《陕西中医》.1989,第10卷(第11期),493. * |
| 等.利胆和胃冲剂的制备及临床观察.《中药材》.1996,第19卷(第10期),537～538. |
| 等.自拟疏肝利胆汤治疗慢性胆囊炎142例.《陕西中医》.1989,第10卷(第11期),493. |
| 胡同瑜 |
| 胡同瑜;等.利胆和胃冲剂的制备及临床观察.《中药材》.1996,第19卷(第10期),537～538. * |
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