CN102123738A - 用于检测发育异常的方法 - Google Patents

用于检测发育异常的方法 Download PDF

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Publication number
CN102123738A
CN102123738A CN2009801324664A CN200980132466A CN102123738A CN 102123738 A CN102123738 A CN 102123738A CN 2009801324664 A CN2009801324664 A CN 2009801324664A CN 200980132466 A CN200980132466 A CN 200980132466A CN 102123738 A CN102123738 A CN 102123738A
Authority
CN
China
Prior art keywords
peptide
definition
imaging
preparation
reporter molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801324664A
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English (en)
Chinese (zh)
Inventor
A·丹尼卡斯
B·吉尔贝尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
GE Healthcare AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare AS filed Critical GE Healthcare AS
Publication of CN102123738A publication Critical patent/CN102123738A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Peptides Or Proteins (AREA)
CN2009801324664A 2008-08-15 2009-08-14 用于检测发育异常的方法 Pending CN102123738A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8907308P 2008-08-15 2008-08-15
GBGB0814960.1A GB0814960D0 (en) 2008-08-15 2008-08-15 Method for detecting dysplasia
GB0814960.1 2008-08-15
US61/089073 2008-08-15
PCT/EP2009/060571 WO2010018230A2 (en) 2008-08-15 2009-08-14 Method for detecting dysplasia

Publications (1)

Publication Number Publication Date
CN102123738A true CN102123738A (zh) 2011-07-13

Family

ID=39812114

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801324664A Pending CN102123738A (zh) 2008-08-15 2009-08-14 用于检测发育异常的方法

Country Status (6)

Country Link
US (1) US20110268660A1 (enExample)
EP (1) EP2326352A2 (enExample)
JP (1) JP2012500191A (enExample)
CN (1) CN102123738A (enExample)
GB (1) GB0814960D0 (enExample)
WO (1) WO2010018230A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115010850A (zh) * 2022-06-08 2022-09-06 上海大学 具有交联稳定结构的近红外光热聚合物功能材料、其制备方法及其应用

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140276107A1 (en) * 2011-10-14 2014-09-18 Photocure Asa Photodynamic diagnosis
US20130116404A1 (en) 2011-11-08 2013-05-09 Case Western Reserve University Targeted non-invasive imaging probes of egfr expressing cells
JP7181875B2 (ja) 2016-09-22 2022-12-01 ユニバーシティー オブ ロード アイランド ボード オブ トラスティーズ pHトリガーポリペプチドにコンジュゲートしたフルオロフォアを含む蛍光化合物
US11702462B2 (en) 2017-07-19 2023-07-18 Rutgers, The State University Of New Jersey Gene transfer systems for stem cell engineering
WO2019183633A1 (en) 2018-03-23 2019-09-26 Case Western Reserve Univeristy Psma targeted conjugate compounds and uses thereof
EP4149557A4 (en) * 2020-05-13 2025-01-15 The University of North Carolina at Chapel Hill Nucleic acid ligand conjugates and use thereof for delivery to cells
KR20230098281A (ko) * 2020-10-27 2023-07-03 위스콘신 얼럼나이 리서어치 화운데이션 조합 면역요법을 위한 모듈형 덴드론 미셀
US20250332265A1 (en) 2021-11-09 2025-10-30 Case Western Reserve University Psma targeted conjugate compounds and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005058371A1 (en) * 2003-12-18 2005-06-30 Amersham Health As Optical imaging contrast agents
CN1676166A (zh) * 2004-03-31 2005-10-05 上海新世界基因技术开发有限公司 与人表皮生长因子受体egfr特异性结合的配体寡肽
WO2007115571A2 (en) * 2006-04-07 2007-10-18 Enkam Pharmaceuticals A/S Erbb receptor-derived peptide fragments
WO2009062399A1 (en) * 2007-11-05 2009-05-22 Shanghai Jiaotong University Peptide ligand directed drug delivery

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1679082A1 (en) * 2005-01-07 2006-07-12 Schering AG Use of cyanine dyes for the diagnosis of proliferative diseases
WO2007042289A2 (en) * 2005-10-11 2007-04-19 Ablynx N.V. Nanobodies™ and polypeptides against egfr and igf-ir

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005058371A1 (en) * 2003-12-18 2005-06-30 Amersham Health As Optical imaging contrast agents
CN1676166A (zh) * 2004-03-31 2005-10-05 上海新世界基因技术开发有限公司 与人表皮生长因子受体egfr特异性结合的配体寡肽
WO2007115571A2 (en) * 2006-04-07 2007-10-18 Enkam Pharmaceuticals A/S Erbb receptor-derived peptide fragments
WO2009062399A1 (en) * 2007-11-05 2009-05-22 Shanghai Jiaotong University Peptide ligand directed drug delivery

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115010850A (zh) * 2022-06-08 2022-09-06 上海大学 具有交联稳定结构的近红外光热聚合物功能材料、其制备方法及其应用
CN115010850B (zh) * 2022-06-08 2023-09-15 上海大学 具有交联稳定结构的近红外光热聚合物功能材料、其制备方法及其应用

Also Published As

Publication number Publication date
EP2326352A2 (en) 2011-06-01
WO2010018230A2 (en) 2010-02-18
GB0814960D0 (en) 2008-09-24
JP2012500191A (ja) 2012-01-05
WO2010018230A3 (en) 2010-04-08
US20110268660A1 (en) 2011-11-03

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Legal Events

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C06 Publication
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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20110713