CN102112436A - 用于合成氨基酸的新的和有效方法 - Google Patents

用于合成氨基酸的新的和有效方法 Download PDF

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Publication number
CN102112436A
CN102112436A CN2009801294480A CN200980129448A CN102112436A CN 102112436 A CN102112436 A CN 102112436A CN 2009801294480 A CN2009801294480 A CN 2009801294480A CN 200980129448 A CN200980129448 A CN 200980129448A CN 102112436 A CN102112436 A CN 102112436A
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CN
China
Prior art keywords
group
described method
methyl
acid
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801294480A
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English (en)
Chinese (zh)
Inventor
维纳亚克·戈雷
马赫什库马·加达卡尔
达塔特雷亚·辛德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Generics UK Ltd
Original Assignee
Generics UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Generics UK Ltd filed Critical Generics UK Ltd
Publication of CN102112436A publication Critical patent/CN102112436A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN2009801294480A 2008-06-03 2009-06-03 用于合成氨基酸的新的和有效方法 Pending CN102112436A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN985/KOL/2008 2008-06-03
IN985KO2008 2008-06-03
PCT/GB2009/050612 WO2009147434A1 (en) 2008-06-03 2009-06-03 A novel and efficient method for the synthesis of an amino acid

Publications (1)

Publication Number Publication Date
CN102112436A true CN102112436A (zh) 2011-06-29

Family

ID=40999769

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801294480A Pending CN102112436A (zh) 2008-06-03 2009-06-03 用于合成氨基酸的新的和有效方法

Country Status (7)

Country Link
US (1) US20110190393A1 (https=)
EP (1) EP2280930A1 (https=)
JP (1) JP2011522027A (https=)
CN (1) CN102112436A (https=)
AU (1) AU2009254931A1 (https=)
CA (1) CA2723871A1 (https=)
WO (1) WO2009147434A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103193615A (zh) * 2013-03-26 2013-07-10 河北科技大学 5-氯戊酰氯的合成新方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2383255A1 (en) 2010-04-28 2011-11-02 Lacer, S.A. New compounds, synthesis and use thereof in the treatment of pain
CN106488906B (zh) * 2014-06-12 2018-10-26 斯福瑞有限公司 β-取代的γ-氨基羧酸的制备方法
JP6704577B2 (ja) * 2015-02-23 2020-06-03 国立大学法人 奈良先端科学技術大学院大学 カーボンナノチューブ−ドーパント組成物複合体の製造方法およびカーボンナノチューブ−ドーパント組成物複合体
US11000541B1 (en) * 2020-05-11 2021-05-11 Donald Richard Wilshe Medicine composition for facilitating treating organs of a mammal

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1642899A (zh) * 2002-01-25 2005-07-20 格吕伦塔尔有限公司 生产取代的丙烯酸酯的方法和后者用于生产取代的$g(g)－氨基酸的应用
WO2006110783A2 (en) * 2005-04-11 2006-10-19 Teva Pharmaceutical Industries Ltd. Process for making (s)-pregabalin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637767A (en) * 1995-06-07 1997-06-10 Warner-Lambert Company Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid
EP1140793B1 (en) * 1998-12-29 2003-09-24 Richter Gedeon Vegyeszeti Gyar R.T. Process for the synthesis of 1-(aminomethyl)cyclohexyl-acetic acid
HU225502B1 (en) * 1998-12-29 2007-01-29 Richter Gedeon Vegyeszet Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates
CN101362696A (zh) * 2008-09-27 2009-02-11 开原亨泰精细化工厂 3-氨甲基-5-甲基己酸即混旋普瑞巴林的制备新方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1642899A (zh) * 2002-01-25 2005-07-20 格吕伦塔尔有限公司 生产取代的丙烯酸酯的方法和后者用于生产取代的$g(g)－氨基酸的应用
WO2006110783A2 (en) * 2005-04-11 2006-10-19 Teva Pharmaceutical Industries Ltd. Process for making (s)-pregabalin

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DAVID A. EVANS ET AL.: "Ni(II)-Bis[(R,R)-N,N＇-dibenzylcyclohexane-1,2-diamine]Br2 Catalyzed Enantioselective Michael Additions of 1,3-Dicarbonyl Compounds to Conjugated Nitroalkenes", 《J. AM. CHEM. SOC.》 *
HIROAKI GOTOH ET AL.: "Diphenylprolinol Silyl Ether as Catalyst of an Asymmetric, Catalytic, and Direct Michael Reaction of Nitroalkanes with α,β-Unsaturated Aldehydes", 《ORG. LETT.》 *
JASON A. WEEDEN ET AL.: "Phosphine-catalyzed nitroaldol reactions", 《TETRAHEDRON LETTERS》 *
SARAH L. POE ET AL.: "Mechanism and Application of a Microcapsule Enabled Multicatalyst Reaction", 《J. AM. CHEM. SOC.》 *
TOMOTAKA OKINO ET AL.: "Enantio- and Diastereoselective Michael Reaction of 1,3-Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea", 《J. AM. CHEM. SOC.》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103193615A (zh) * 2013-03-26 2013-07-10 河北科技大学 5-氯戊酰氯的合成新方法

Also Published As

Publication number Publication date
CA2723871A1 (en) 2009-12-10
AU2009254931A1 (en) 2009-12-10
US20110190393A1 (en) 2011-08-04
WO2009147434A1 (en) 2009-12-10
JP2011522027A (ja) 2011-07-28
EP2280930A1 (en) 2011-02-09

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Application publication date: 20110629