CN102099042B - 用于贫血或幽门螺杆菌感染的单独(羟基吡喃酮铁)和组合(羟基吡喃酮铁和胃肠道炎症抑制剂)组合物 - Google Patents

用于贫血或幽门螺杆菌感染的单独(羟基吡喃酮铁)和组合(羟基吡喃酮铁和胃肠道炎症抑制剂)组合物 Download PDF

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CN102099042B
CN102099042B CN200980125291.4A CN200980125291A CN102099042B CN 102099042 B CN102099042 B CN 102099042B CN 200980125291 A CN200980125291 A CN 200980125291A CN 102099042 B CN102099042 B CN 102099042B
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iron
application
compositions
acid
gastrointestinal tract
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CN102099042A (zh
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迈克尔·亚瑟·施托克哈姆
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Medical Research Council
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Iron Therapeutics Holdings AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200980125291.4A 2008-05-15 2009-05-14 用于贫血或幽门螺杆菌感染的单独(羟基吡喃酮铁)和组合(羟基吡喃酮铁和胃肠道炎症抑制剂)组合物 Active CN102099042B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0808835.3 2008-05-15
GBGB0808835.3A GB0808835D0 (en) 2008-05-15 2008-05-15 Therapeutic compositions
PCT/GB2009/001231 WO2009138761A1 (en) 2008-05-15 2009-05-14 Mono ( iron hydroxypyrone ) and combination ( iron hydroxypyrone and gi inflammation inhibiting agents ) compositions for anaemia or h. pylori infections

Publications (2)

Publication Number Publication Date
CN102099042A CN102099042A (zh) 2011-06-15
CN102099042B true CN102099042B (zh) 2014-08-13

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980125291.4A Active CN102099042B (zh) 2008-05-15 2009-05-14 用于贫血或幽门螺杆菌感染的单独(羟基吡喃酮铁)和组合(羟基吡喃酮铁和胃肠道炎症抑制剂)组合物

Country Status (9)

Country Link
US (2) US9248148B2 (https=)
EP (1) EP2303289A1 (https=)
JP (2) JP5769308B2 (https=)
CN (1) CN102099042B (https=)
AU (1) AU2009247762B2 (https=)
CA (1) CA2724172C (https=)
GB (1) GB0808835D0 (https=)
SG (1) SG182137A1 (https=)
WO (1) WO2009138761A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104829272A (zh) 2009-12-22 2015-08-12 拉尔科营养品有限公司 有机螯合的矿物组合物及其制备方法
GB201101370D0 (en) 2011-01-27 2011-03-09 Iron Therapeutics Holdings Ag Process
CN104640825A (zh) * 2012-07-05 2015-05-20 拉尔科营养品有限公司(美国) 利用矿物质化合物的农业组合物和应用
US10179120B2 (en) * 2014-01-06 2019-01-15 Iron Therapeutics Holdings Ag Dosage regimen of ferric trimaltol
GB201404390D0 (en) * 2014-03-12 2014-04-23 Iron Therapeutics Holdings Ag Composition
UA117786C2 (uk) 2014-04-17 2018-09-25 Ралко Нутрітіон, Інк. Сільськогосподарські композиції та застосування з використанням мінеральних сполук
GB201418710D0 (en) 2014-10-21 2014-12-03 Iron Therapeutics Holdings Ag Dosage regimen
WO2016112381A1 (en) 2015-01-09 2016-07-14 The Board Of Trustees Of The University Of Illinois Restoring physiology in iron-deficient organisms using small molecules
JP2017032550A (ja) * 2015-07-30 2017-02-09 大塚製薬株式会社 胃粘膜萎縮の有無を判定する方法
CA3019478C (en) * 2016-03-31 2024-02-13 United Kingdom Research And Innovation Ferric maltol compositions for use in the treatment or prevention of cancer and tumours
GB2553099A (en) * 2016-08-19 2018-02-28 Shield Tx Uk Ltd Use
IT201700021676A1 (it) * 2017-02-28 2018-08-28 Carlo Angelo Ghisalberti Composizioni e sistemi di estrazione del ferro non-eme dalla dieta per uso nell’anemia sideropenica e carenze marziali

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998016218A1 (en) * 1996-10-11 1998-04-23 Pfylori Limited Use of metal complexes to treat gastrointestinal infections

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
EP0107458B1 (en) 1982-10-22 1987-07-29 National Research Development Corporation Pharmaceutical compositions
US5177068A (en) 1984-04-19 1993-01-05 National Research Development Corporation Pharmaceutical compositions
AU6010696A (en) 1995-06-10 1997-01-09 Vitra Pharmaceuticals Ltd Iron compounds, compositions, methods of making the same and uses thereof
GB9710699D0 (en) 1997-05-24 1997-07-16 Danbiosyst Uk Gastro-retentive controlled release system
GB0012487D0 (en) 2000-05-24 2000-07-12 Pfylori Limited Use of metal compounds to treat gastrointestinal infections
US7135196B2 (en) * 2000-09-19 2006-11-14 Vitra Pharmaceuticals Limited Iron compositions
GB0211500D0 (en) 2002-05-18 2002-06-26 Vitra Pharmaceuticals Ltd Method of forming iron hydroxypyrone compounds
EP1686982A4 (en) 2003-11-19 2007-03-21 Vecta Ltd METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH HELICOBACTER PYLORI USING COMPOUNDS CONTAINING ENDOPEROXIDE BRIDGE
EP1973549B1 (en) * 2006-01-06 2016-07-20 Luitpold Pharmaceuticals, Inc. Methods and compositions for administration of iron
WO2007108712A1 (en) 2006-03-17 2007-09-27 Tatyana Vyacheslavovna Popkova Kit and method for treating or preventing anemia caused by iron deficiency
TW200843802A (en) * 2007-02-09 2008-11-16 Drugtech Corp Compositions for improving gastrointestinal nutrient and drug absorption

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998016218A1 (en) * 1996-10-11 1998-04-23 Pfylori Limited Use of metal complexes to treat gastrointestinal infections

Also Published As

Publication number Publication date
JP5769308B2 (ja) 2015-08-26
WO2009138761A1 (en) 2009-11-19
GB0808835D0 (en) 2008-06-18
US20110177172A1 (en) 2011-07-21
US9248148B2 (en) 2016-02-02
SG182137A1 (en) 2012-07-30
AU2009247762B2 (en) 2014-08-14
JP2011520855A (ja) 2011-07-21
CN102099042A (zh) 2011-06-15
CA2724172C (en) 2017-07-25
AU2009247762A1 (en) 2009-11-19
CA2724172A1 (en) 2009-11-19
US20160120902A1 (en) 2016-05-05
EP2303289A1 (en) 2011-04-06
JP2015083572A (ja) 2015-04-30

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