CN102091267B - Medicament for treating psoriasis vulgaris and preparation method thereof - Google Patents
Medicament for treating psoriasis vulgaris and preparation method thereof Download PDFInfo
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- CN102091267B CN102091267B CN2011100220807A CN201110022080A CN102091267B CN 102091267 B CN102091267 B CN 102091267B CN 2011100220807 A CN2011100220807 A CN 2011100220807A CN 201110022080 A CN201110022080 A CN 201110022080A CN 102091267 B CN102091267 B CN 102091267B
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Abstract
The invention relates to a medicament for treating psoriasis vulgaris and a preparation method thereof. The medicament provided by the invention comprises the following raw materials in parts by weight: 30-45 parts of glabrous greenbrier rhizome, 20-30 parts of smilax, 9-12 parts of red peony root, 10-15 parts of safflower, 15-30 parts of sophora japonica, 10-15 parts of wild chrysanthemum flower, 10-15 parts of spina gleditsiae, 30-45 parts of dandelion, 10-15 parts of forsythia, 6-10 parts of scorpion, 20-30 parts of honeysuckle, 9-15 parts of radix rehmanniae, 9-12 parts of angelica sinensis, 15-20 parts of red sage root and 20-30 parts of dittany bark. The preparation method comprises the following steps: a, weighing all raw materials according to the parts by weight; b, putting the weighed raw materials into a medicine pot and adding water for soaking; c, boiling with strong fire and then decocting for 20-40 minutes with slow fire, filtering the decoction; and d, adding water to the medicine pot, boiling with strong fire and then decocting for 20-30 minutes with slow fire, filtering the decoction and mixing evenly with the decoction filtered for the first time. The medicament provided by the invention has very good curative effects on patients with psoriasis vulgaris at the active stage and the resting stage, and is safe and efficient without side effects.
Description
One, technical field
The present invention relates to psoriatic medicine of a kind of treatment and preparation method thereof, more definite saying is medicine of treatment psoriasis vulgaris and preparation method thereof, belongs to Chinese herbal treatment psoriasis technical field.
Two, background technology
Psoriasis is commonly called as " psoriasis ", is that a kind of chronic recurrent inflammatory skin is sick, and typical skin lesion is a squama property erythema.Its pathogenic factor is still indeterminate, and is how relevant with inherited genetic factors, infective agent, dysbolismus, Nervous and Mental Factors, immunologic function disorder etc.Chinese medicine is referred to as the Bai Mange with psoriasis.
Pathogenesis is that the plain body sun of patient heat is contained partially, or attacked by six climate exopathogens, in accumulate the heresy of burning hot turbid damp wind heat, hinder in skin, do not pent up and loose, the body intrinsic heat is contained partially, or throws off restraint the strongly fragrant and heat-transformation of the pungent delicious food of food, pyretic toxicity accumulates in blood system, blood hot air wind producing and send out primary disease.The primary disease cause of disease is complicated, and the clinical manifestation variation is divided into four types of homeliness type, impetigo type, arthrosis type and erythrodermics according to the clinical manifestation difference.Psoriasis vulgaris is clinical modal a kind of; Show as follows: skin lesion is red pimple or maculopapule; Boundary is obvious, and the silvery white squama of surface-coated multilamellar scrapes off the visible luminous semitransparent thin film of pale red of squama layer; Peel off the visible petechial hemorrhage (Auspitz's sign) of thin film, possess above-mentioned characteristic and can be diagnosed as psoriasis.
The present treatment of psoriasis does not still have effect method, and very easily recurrence, and is very big to patient's health and psychological impact; The easy Drug abuse treatment of patient; Cause treating lack of standardization, have take for a long time toxic and side effects big, to the tangible medicine of hepatorenal damage, the long-term large dose oral administration corticosteroid hormone that has; Heavy metal Drug therapys such as the leaded hydrargyrum of external that has, result make psoriasis vulgaris develop into intractable psoriasises such as impetigo type, arthrosis type, erythrodermic.Cause alopecia, the skin large tracts of land that also have are stripped off, hepatic and renal function injure, even be transformed into critical illness such as leukemia, and jeopardize patient's life, cause great infringement for patient's health.
Three, summary of the invention
The objective of the invention is to solve the deficiency of above-mentioned prior art aspect the treatment psoriasis; Medicine of a kind of safe and efficient treatment psoriasis vulgaris that has no side effect and preparation method thereof is provided, is particularly suitable for the psoriatic of the with the passing of time prolonged and repeated outbreak of the course of disease.
The present invention realizes through following technical scheme:
A kind of medicine of treating psoriasis vulgaris, its special character is: the raw material that comprises following weight portion in the said medicine:
30～45 parts of Rhizoma Smilacis Glabraes, 20～30 parts of Rhizoma Smilacis Chinensiss, 9～12 parts of Radix Paeoniae Rubra, 10～15 parts on Flos Carthami, 15～30 parts of the living Flos Sophorae Immaturus, 10～15 parts of Flos Chrysanthemi Indicis, 10～15 parts of Spina Gleditsiae, 30～45 parts of Herba Taraxaci, 10～15 parts of Fructus Forsythiaes, 6～10 parts of Scorpios, 20～30 parts of Flos Loniceraes, 9～15 parts in the Radix Rehmanniae, 9～12 parts of Radix Angelicae Sinensis, 15～20 parts of Radix Salviae Miltiorrhizaes, 20～30 parts of Cortex Dictamni.
Manufacturing method for above mentioned medicine, its special character is may further comprise the steps:
A, take by weighing various raw materials according to said weight portion;
B, the various raw materials that will take by weighing are put into medicinal cupping, add water by weight and soak 20～40 minutes for 550～650 parts;
After c, very hot oven are fried boiling, change slow fire and fried in shallow oil the leaching medicinal liquid 20～40 minutes;
D, in medicinal cupping, add 450～550 parts in water again, the very hot oven back slow fire that is fried boiling was fried in shallow oil 20～30 minutes, the leaching medicinal liquid and with leaching first time medicinal liquid mixing.
Drug administration method of the present invention: respectively obey 200ml on an empty stomach every day sooner or later, and 30 days is a course of treatment.Period in a medicine avoids pungent food, fish and shrimp, can not drink.
The present invention treats the main effect of various raw materials in the psoriatic medicine:
Rhizoma Smilacis Glabrae: have detoxifcation, dehumidifying, the effect in sharp joint.Control syphilis, eczema, carbuncle, scrofula, and can separate hydrargyrum powder, Vermilion chronic poisoning.Be used for fire-toxin carbuncle furuncle in addition, pyretic stranguria, cards such as the puckery pain of dark coloured urine.Compendium of Material Medica is said " curing rheumatism, sharp joint, stopping leak rushes down, and controls the contracture osteodynia, the malignant boil carbuncle is separated hydrargyrum powder Vermilion poison for strengthening the spleen and stomach, bone and muscle strengthening ".
Rhizoma Smilacis Chinensis: another name China root greenbrier rhizome, expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling.Control muscles and bones aching, the severe and migratory arthralgia gout is had loose bowels, dysentery, and edema, gonorrhea is quenched one's thirst, leukorrhagia, chyluria, scrofula, hemorrhoid, psoriasis, furuncle swelling toxin.Closely be used for alimentary tract cancer, certain effect arranged improving symptom.
Radix Paeoniae Rubra: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.(1) controls calentura and send out speckle, spit blood knob blood, dysentery, discharging fresh blood stool.(2) control amenorrhea, dysmenorrhea, abdominal pain due to blood stasis, costa sternales pain, conjunctival congestion, carbuncle, traumatic injury.
Flos Carthami: blood circulation promoting and blood stasis dispelling, stimulate the menstrual flow.Be mainly used in dysmenorrhea, amenorrhea due to stagnation of blood, postpartum stagnation stomachache, bruise Ji cards such as mass in the abdomen.Be used for traumatic injury, pain due to blood stasis; And card such as joint
pain; Can also be used for sore and toxic, with promoting blood circulation and detumescence.Compendium of Material Medica cloud " invigorate blood circulation and moisturize, pain-relieving powder for treating is swollen, stimulates the menstrual flow "
The living Flos Sophorae Immaturus: be the alabastrum of Flos Sophorae.Heat clearing away, removing heat from blood, hemostasis.Control hematochezia, hemorrhoid blood, prolapse of the anus, hematuria, knob blood, wind-heat hot eyes, high blood pressure are spitted blood in uterine bleeding.
Flos Chrysanthemi Indici: heat-clearing and toxic substances removing, removing heat from blood blood pressure lowering.Control influenza, epidemic cerebrospinal meningitis, hepatitis, headache, wood is red, hypertension.Also control the carbuncle furunculosis, scrofula, aphtha, erysipelas, eczema, pemphigus.
Spina Gleditsiae: the evacuation of pus of invigorating blood circulation of subsiding a swelling, search the wind parasite killing.Control carbuncle resistance toxic swelling, treating acute tonsillitis, leprosy.
Herba Taraxaci: heat-clearing and toxic substances removing, dampness removing.Be used for fire-toxin skin ulcer furuncle, acute mastitis acute appendicitis, the card of fever, redness, swelling and pain such as erysipelas more.
Fructus Forsythiae: heat-clearing and toxic substances removing, the eliminating carbuncle eliminating stagnation is controlled anemopyretic cold, laryngopharynx swelling and pain, macule, sore swollen toxin, scrofula, erysipelas, hot woods, dysuria.
Scorpio: relieve dizziness, high fever, infantile convulsions, epilepsy, etc., spasmolytic, collateral dredging, detoxifcation is controlled infantile convulsion, epilepsy, apoplexy and hemiplegia, facial hemiparalysis, tetanus, rheumatic arthralgia, tuberculous lymphadenitis, sore swollen toxin.
Flos Lonicerae: heat-clearing and toxic substances removing, control anemopyretic cold, epidemic febrile disease initial stage, laryngopharynx swelling and pain, carbuncle furuncle abscess, erysipelas, acute mastitis, appendicitis, toxic-heat and blood stasis.
The Radix Rehmanniae: clearing away heat and nourishing YIN, removing heat from blood is moisturized, and controls the epidemic febrile disease heating, and crimson tongue is thirsty, and fever due to yin deficiency is quenched one's thirst, spits blood, knob blood, metrorrhagia, menoxenia, the moon is hindered constipation.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menoxenia is controlled in the regulating menstruation intestine moistening, amenorrhea, dysmenorrhea, metrorrhagia.Eliminate-poverty blood, headache due to deficiency of blood, dizzy, constipation.The Zhi lumps in the chest and abdomen, rheumatic arthralgia, carbuncle resistance skin infection, traumatic injury.
Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind is controlled menoxenia, amenorrhea, dysmenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal.The Zhi lumps in the chest and abdomen, rheumatic arthralgia, cardiopalmus, insomnia.
Cortex Dictamni: dispeiling pathogenic wind and removing dampness, heat-clearing and toxic substances removing is controlled skin pruritus, urticaria, eczema, scabies, impetigo is controlled lymphadenitis.
We's compatibility has heat-clearing and toxic substances removing, blood enriching and dryness moistening, blood circulation promoting and blood stasis dispelling, the effect of dispelling wind for relieving itching.Having mutual synergism between the various medicines, psoriasis vulgaris is carried out resting stage phase patient have extraordinary curative effect, is the psoriatic medicine of a kind of safe and efficient treatment that has no side effect.
Four, the specific embodiment
Below provide the specific embodiment of the present invention, be used for formation of the present invention is further specified.
Embodiment 1
A kind of medicine of treating psoriasis vulgaris comprises the raw material of following weight portion in the medicine:
30 parts of Rhizoma Smilacis Glabraes, 20 parts of Rhizoma Smilacis Chinensiss, 9 parts of Radix Paeoniae Rubra, 10 parts on Flos Carthami, 15 parts of the living Flos Sophorae Immaturus, 10 parts of Flos Chrysanthemi Indicis, 10 parts of Spina Gleditsiae, 30 parts of Herba Taraxaci, 10 parts of Fructus Forsythiaes, 6 parts of Scorpios, 20 parts of Flos Loniceraes, 9 parts in the Radix Rehmanniae, 9 parts of Radix Angelicae Sinensis, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Cortex Dictamni.
Embodiment 2
A kind of medicine of treating psoriasis vulgaris comprises the raw material of following weight portion in the medicine:
40 parts of Rhizoma Smilacis Glabraes, 25 parts of Rhizoma Smilacis Chinensiss, 10 parts of Radix Paeoniae Rubra, 12 parts on Flos Carthami, 25 parts of the living Flos Sophorae Immaturus, 12 parts of Flos Chrysanthemi Indicis, 12 parts of Spina Gleditsiae, 35 parts of Herba Taraxaci, 12 parts of Fructus Forsythiaes, 8 parts of Scorpios, 25 parts of Flos Loniceraes, 12 parts in the Radix Rehmanniae, 10 parts of Radix Angelicae Sinensis, 18 parts of Radix Salviae Miltiorrhizaes, 25 parts of Cortex Dictamni.
Embodiment 3
A kind of medicine of treating psoriasis vulgaris comprises the raw material of following weight portion in the medicine:
45 parts of Rhizoma Smilacis Glabraes, 30 parts of Rhizoma Smilacis Chinensiss, 12 parts of Radix Paeoniae Rubra, 15 parts on Flos Carthami, 30 parts of the living Flos Sophorae Immaturus, 15 parts of Flos Chrysanthemi Indicis, 15 parts of Spina Gleditsiae, 45 parts of Herba Taraxaci, 15 parts of Fructus Forsythiaes, 10 parts of Scorpios, 30 parts of Flos Loniceraes, 15 parts in the Radix Rehmanniae, 12 parts of Radix Angelicae Sinensis, 20 parts of Radix Salviae Miltiorrhizaes, 30 parts of Cortex Dictamni.
More than medicine among each embodiment, prepare according to following steps:
A, take by weighing various raw materials according to said weight portion;
B, the various raw materials that will take by weighing are put into medicinal cupping, add water by weight and soak 20～40 minutes for 550～650 parts;
After c, very hot oven are fried boiling, change slow fire and fried in shallow oil the leaching medicinal liquid 20～40 minutes;
D, in medicinal cupping, add 450～550 parts in water again, the very hot oven back slow fire that is fried boiling was fried in shallow oil 20～30 minutes, the leaching medicinal liquid and with leaching first time medicinal liquid mixing.
Above embodiment Chinese medicine instructions of taking: respectively obey 200ml on an empty stomach every day sooner or later, and 30 days is a course of treatment.Period in a medicine avoids pungent food, fish and shrimp, can not drink.
For showing the curative effect of medicine of the present invention, carried out clinical comparison.With Drug therapy psoriasis vulgaris 226 examples of the present invention, wherein male 122 examples, women 104 examples, at minimum 12 years old of age, maximum 68 years old, the course of disease is the shortest 3 months, and was the longest 10 years, the shortest taking medicine a course of treatment, the longest taking medicine four courses of treatment.226 routine patients cure 89 examples altogether, account for 39.4%; Produce effects 92 examples account for 40.7%; Effective 29 examples account for 12.8%; Invalid 16 examples account for 7.1%, and clinical total effective rate reaches 92.9%.
Curative effect determinate standard:
Recovery from illness: erythra all disappears did not have recurrence in 3 years;
Produce effects: deflorescence reaches more than 80%;
Effectively: erythra partly disappears, and pruritus alleviates;
Invalid: erythra does not have obvious improvement or continues to increase the weight of.
For showing the curative effect of Chinese medicine of the present invention, the spy provides clinical typical case history:
Case one: Lee so-and-so, man, 18 years old, student.A whole body erythema, pimple, squama were itched 2 years, and increase the weight of every winter, and alleviate summer, was psoriasis vulgaris at certain hospital diagnosis once, oral enlightening silver strip, and the treatment of external PIYANNING DING, the state of an illness once took a turn for the better, and recurred after the drug withdrawal.Introduce here to go to a doctor through others; Have a medical check-up: patient's scalp, trunk, extremity scatter beans greatly to Ovum Columba livia great red spot, pimple, on cover silvery white squama, strike off squama and see that bright thin film phenomenon and dewdrop shape are hemorrhage; Be diagnosed as psoriasis vulgaris; Serve on January for above-mentioned Chinese medicine composition, deflorescence does not see that new erythra occurs and exceedes.
Case two: week certain, the man, 42 years old, because of silvery white squama surplus first visit half a year of the general rubescent speckle of whole body, surface attachment.From the beginning of skin lesion is Semen phaseoli radiati large red pimple, enlarges gradually to be fused into speckle, covers silvery white squama on it, for very, accompanies pruritus endlessly with trunk, through medication treatment, and no positive effect.Have a medical check-up: obesity, scalp, trunk, extremity are seen large stretch of light red mottle, and the silvery white squama of surface coverage multilamellar is scraped it with hands, and the bottom surface sees that the sieve shape is hemorrhage.Red tongue with yellow fur, stringy and rolling pulse.Diagnosis: white Mange (psoriasis), control with clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, it is for oral administration to give Chinese medicine composition side's decocting, and skin lesion obviously alleviates after 10 doses, and stable disease obtains effect after cutting out 30 doses adding on this side basis to simplify.
Case three: grandson so-and-so, woman 34 years old, the workman suffered from psoriasis 10 years, once multi-treatment was not seen to be clearly better, the state of an illness has and increases the weight of trend year by year, introduces the here treatment through friend.The erythema pimple that patient is gathered all over the body and differed in size distributes in flakes, the shape irregularity, on cover thicker silvery white squama, see thin film phenomenon and petechial hemorrhage, be diagnosed as psoriasis vulgaris.Be decocted in water for oral dose for Chinese medicine composition side, the Zhou patient's scratchiness of taking medicine alleviates, and erythra continues to enlarge again, takes medicine deflorescence and fully recovering two months.
Case four: high so-and-so, man, 58 years old, peasant.Suffer from two more than ten years of psoriasis, whole body erythema pimple, the large stretch of distribution merged like coin shape, map shape mutually, attach most importance to abdominal part, back especially, on cover the multiple white squama, hemorrhage after scratching, once arrived how tame hospital dermatology department diagnosis and treatment, all do not have obvious curative effects.Take this Chinese medicine composition treatment after one month, the state of an illness is clearly better, the erythra deepening, and the squama attenuation does not have new erythra and occurs.After taking medicine three months, erythra all disappears and heals, and recurrence was not seen in drug withdrawal in 3 years.
Claims (2)
1. a medicine of treating psoriasis vulgaris is characterized in that the raw material of Chinese medicine in the said medicine is: 30～45 parts of Rhizoma Smilacis Glabraes, 20～30 parts of Rhizoma Smilacis Chinensiss, 9～12 parts of Radix Paeoniae Rubra, 10～15 parts on Flos Carthami, 15～30 parts of the living Flos Sophorae Immaturus, 10～15 parts of Flos Chrysanthemi Indicis, 10～15 parts of Spina Gleditsiae, 30～45 parts of Herba Taraxaci, 10～15 parts of Fructus Forsythiaes, 6～10 parts of Scorpios, 20～30 parts of Flos Loniceraes, 9～15 parts in the Radix Rehmanniae, 9～12 parts of Radix Angelicae Sinensis, 15～20 parts of Radix Salviae Miltiorrhizaes, 20～30 parts of Cortex Dictamni.
2. the said a kind of medicine of treating psoriasis vulgaris of claim 1 is characterized in that may further comprise the steps the method for preparing of said medicine:
A, take by weighing various raw materials according to said weight portion;
B, the various raw materials that will take by weighing are put into medicinal cupping, add water by weight and soak 20～40 minutes for 550～650 parts;
After c, very hot oven are fried boiling, change slow fire and fried in shallow oil the leaching medicinal liquid 20～40 minutes;
D, in medicinal cupping, add 450～550 parts in water again, the very hot oven back slow fire that is fried boiling was fried in shallow oil 20～30 minutes, the leaching medicinal liquid and with leaching first time medicinal liquid mixing.
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| CN2011100220807A CN102091267B (en) | 2011-01-14 | 2011-01-14 | Medicament for treating psoriasis vulgaris and preparation method thereof |
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| CN2011100220807A CN102091267B (en) | 2011-01-14 | 2011-01-14 | Medicament for treating psoriasis vulgaris and preparation method thereof |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105250794A (en) * | 2015-11-23 | 2016-01-20 | 俞成莲 | Medicine used for treating blood-heat type psoriasis |
| CN105250792A (en) * | 2015-11-23 | 2016-01-20 | 俞成莲 | Medicine used for treating pustular psoriasis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1129577A (en) * | 1995-09-15 | 1996-08-28 | 贾阳春 | Pellets for curing tinea |
| CN1242201A (en) * | 1998-07-20 | 2000-01-26 | 徐景信 | Patent traditional Chinese medicine for treating psoriasis, and method for preparing same |
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2011
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1129577A (en) * | 1995-09-15 | 1996-08-28 | 贾阳春 | Pellets for curing tinea |
| CN1242201A (en) * | 1998-07-20 | 2000-01-26 | 徐景信 | Patent traditional Chinese medicine for treating psoriasis, and method for preparing same |
Non-Patent Citations (2)
| Title |
|---|
| 杜锡贤.银屑病.《山东中医杂志》.1995,第14卷(第08期),367. * |
| 罗清等.中医药治疗银屑病近况.《时珍国医国药》.2004,第15卷(第12期),871-872. * |
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