CN102091249A

CN102091249A - Traditional Chinese medicine for treating recurrent bladder cancer

Info

Publication number: CN102091249A
Application number: CN2011100437378A
Authority: CN
Inventors: 张爱霞; 王海荣
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-02-19
Filing date: 2011-02-19
Publication date: 2011-06-15

Abstract

The invention relates to a traditional Chinese medicine for treating recurrent bladder cancer. The traditional Chinese medicine is characterized by comprising the following raw material medicaments by weight: 10 to 14g of codonopsis pilosula, 9 to 12g of astragalus, 10 to 15 parts of largehead atractylodes rhizome, 9 to 12g of Chinese angelica, 10 to 15g of rehmannia root, 8 to 12 parts of coriolus versicolor, 10 to 15 parts of baical skullcap root, 10 to 15 parts of gardenia, 6 to 12 parts of Japanese thistle herbor root, 8 to 12 parts of puff-ball, 6 to 10g of common phellinus fungus, 8 to 12g of lotus rhizome node, 6 to 10g of oriental waterplantain rhizome, 10 to 15g of common lophatherum herb and 6 to 10g of liquoric root. The traditional Chinese medicine is simple in formula and convenient to use, has a good curative effect, high remission rate and low price, does not have toxic or side effects and is suitable for people of all ages and different genders.

Description

A kind of Chinese medicine for the treatment of the recurrent bladder cancer

Technical field

The present invention relates to a kind of Chinese herbal medicine formula, specifically a kind of Chinese medicine for the treatment of the recurrent bladder cancer.

Background technology

Bladder cancer is meant the malignant tumor that is primary in Urothelial Cell, is modal a kind of in the urologic neoplasms.Bladder cancer is mainly in middle age, and for seeing, operative treatment is an optimum selection more with the male, operation can be excised the local patholoic change tissue, but the operation wound just, based on the deficiency of vital energy, the bladder tumor recurrence rate is higher, clinical common recurrent painless hematuria, postoperative chemotherapy has certain therapeutical effect to bladder cancer, but effect is not ideal enough, suppress body's immunological function in addition, therefore the hematozemia of then feeling frustrated has increased the weight of patient's QI and blood deficiency, brings bigger mental pressure and life quality to descend to the patient.

Summary of the invention

The present invention seeks to set upright benefiting QI and nourishing blood, heat-clearing and toxic substances removing, promoting blood circulation and hemostasis, eliminating dampness and diuresis.On the basis of anticancer growth, improve the immunologic function of body self comprehensively, multi-faceted inhibition even kill cancer cell, recurrence, diffusion and the transfer of control tumor fundamentally reach the purpose for the treatment of tumor.

For achieving the above object; a kind of Chinese medicine for the treatment of the recurrent bladder cancer is characterized in that being made up of the component of following raw materials in weight drug ratio: Radix Codonopsis 10～14g, the Radix Astragali 9～12g, the Rhizoma Atractylodis Macrocephalae 10～15g, Radix Angelicae Sinensis 9～12g, the Radix Rehmanniae 10～15g, Coriolous Dersicolor (Fr.) Quel 8～12g, Radix Scutellariae 10～15g, Fructus Gardeniae 10～15g, Radix Cirsii Japonici 6～12g, Lasiosphaera Seu Calvatia 8～12g, Phellinus igniarius (L. ex Fr.) Quel. 6～10g, Nodus Nelumbinis Rhizomatis 8～12g, Rhizoma Alismatis 6～10g, Herba Lophatheri 10～15g, Radix Glycyrrhizae 6～10g.

It is simple, easy to use that prescription of the present invention is treated preparation, and good effect, remission rate height are cheap, have no side effect.

Flat, the sweet in the mouth of Radix Codonopsis, little acid among the present invention; Return spleen, lung meridian.Effect: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, treatment deficiency of both QI and blood." detailed outline is picked up any lost article from the road ": control the deficiency of the lung, lung benefiting gas.Modern Chinese medicine research is thought: enhancing human body immunity, enhancing hemopoietic function, anti-stress effect.Radix Astragali nature and flavor are sweet, tepor; Return lung, spleen, liver, kidney channel.Effect: benefiting QI for strengthening the superficies, arresting sweating take off admittedly, granulation promoting, inducing diuresis to remove edema.Contain various trace elements, have antitumaous effect.Rhizoma Atractylodis Macrocephalae nature and flavor hardship, sweet, warm; Return spleen, stomach warp.The effect invigorating the spleen and benefiting QI, the dampness diuretic.Rhizoma Atractylodis polysaccharide has restitution to lymphocytic propagation function, but the enhancing human body immunity function has antioxidation, anticoagulation, antitumor action.Radix Angelicae Sinensis nature and flavor temperature, ignorant sweet, hot; Return liver, the heart, spleen channel.Has the promoting blood circulation and stopping pain of enriching blood, effect of relaxing bowel.Contain basic lactone, nicotinic acid, sucrose and several amino acids etc., be used for the patient of had repeated hematuria, blood deficiency and yellow complexion, dizzy cardiopalmus.Radix Scutellariae nature and flavor hardship, cold; Return lung, gallbladder, spleen, large intestine, small intestine meridian.Effect: heat clearing and damp drying, eliminating fire and detoxication, hemostasis.Fructus Gardeniae nature and flavor hardship, cold; GUIXIN, liver, lung, stomach warp, tri-jiao channel.Effect: clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, reducing swelling and alleviating pain.Radix Rehmanniae nature and flavor are sweet, bitter, cold; GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid." book on Chinese herbal medicine performance ": clean ancient cloud: Radix Rehmanniae is cold in nature, bitter in the mouth.Effect: removing heat from blood is enriched blood, and the kidney invigorating water kidney-YIN being deficient is controlled few cloudy heat in the heart interior.Coriolous Dersicolor (Fr.) Quel: nature and flavor are sweet, light, be slightly cold.Return liver, spleen, lung meridian.Have heat clearing away, detoxifcation, antiinflammatory, anticancer, effect such as protect the liver.Radix Cirsii Japonici is cool in nature, sweet in the mouth, hardship, goes into four towers.Effect: removing heat from blood, hemostasis, blood stasis dispelling, subduing inflammation.Lasiosphaera Seu Calvatia nature and flavor: hot, flat, nontoxic.Effect: hemostasis, antibiotic, the Lasiosphaera Seu Calvatia preparation has significant anti-cancer activity through animal experiment.The sharp the five internal organs of Phellinus igniarius (L. ex Fr.) Quel., effect: softening the hard mass, toxin expelling, hemostasis is invigorated blood circulation; Can alleviate the side effect of chemicotherapy.The Nodus Nelumbinis Rhizomatis nature and flavor are puckery, and are flat, nontoxic.Effect: hemostasis, dissipating blood stasis; " not Lu " main heat is thirsty, the blood that looses, granulation promoting.The Rhizoma Alismatis effect: diuretic, eliminating dampness by diuresis expels the heat-evil.Control dysuria, the edema distension.Herba Lophatheri nature and flavor: sweet light, cold, nontoxic; Go into heart channel, kidney channel.Effect: the sweet light profit of oozing.Radix Glycyrrhizae property is flat, sweet in the mouth, returns 12 warps.Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.

The manufacture method of Chinese medicine of the present invention is: be decocted in water for oral dose, 1 dose of every day, sub-service sooner or later, 10 days was 1 course of treatment.

The present invention verifies through clinical practice; Short term effect: total remission rate 76.8%; Clinical disease: significantly improve 28 people, partly improve 33 people, do not have 3 people of improvement.Quality of life changes relatively: improve 42 examples, stablize 19 examples, 3 examples that descend, obvious effective rate 95.3%, inefficiency 4.68%.

The specific embodiment

Below in conjunction with implementing case the present invention is further described:

Implement 1: a kind of Chinese medicine for the treatment of the recurrent bladder cancer is characterized in that it is made up of the component of following weight material medicine proportioning: Radix Codonopsis 10～14g, the Radix Astragali 9～12g, the Rhizoma Atractylodis Macrocephalae 10～15g, Radix Angelicae Sinensis 9～12g, the Radix Rehmanniae 10～15g, Coriolous Dersicolor (Fr.) Quel 8～12g, Radix Scutellariae 10～15g, Fructus Gardeniae 10～15g, Radix Cirsii Japonici 6～12g, Lasiosphaera Seu Calvatia 8～12g, Phellinus igniarius (L. ex Fr.) Quel. 6～10g, Nodus Nelumbinis Rhizomatis 8～12g, Rhizoma Alismatis 6～10g, Herba Lophatheri 10～15g, Radix Glycyrrhizae 6～10g.Be decocted in water for oral dose, 1 dose of every day, sub-service sooner or later, 10 days was 1 course of treatment.

Implement 2: a kind of Chinese medicine for the treatment of the recurrent bladder cancer, its preferred side is Radix Codonopsis 12g, Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 10g, Radix Angelicae Sinensis 12g, Radix Rehmanniae 10g, Coriolous Dersicolor (Fr.) Quel 8g, Radix Scutellariae 10g, Fructus Gardeniae 12g, Radix Cirsii Japonici 8g, Lasiosphaera Seu Calvatia 10g, Phellinus igniarius (L. ex Fr.) Quel. 8g, Nodus Nelumbinis Rhizomatis 12g, Rhizoma Alismatis 6～10g, Herba Lophatheri 10g, Radix Glycyrrhizae 8g.Be decocted in water for oral dose, 1 dose of every day, sub-service sooner or later, 10 days was 1 course of treatment.

A kind of Chinese medicine clinical efficacy for the treatment of the recurrent bladder cancer is summed up:

Clinical efficacy is summed up:

One, physical data: select behind the bladder cancer postoperative chemotherapy patient's totally 64 examples, male 56 examples, women 8 examples, age 35-72 year, average 51 years old, the course of disease was in half a year, and average 3-4 month, the patient made a definite diagnosis through hospital above county level and implements above-mentioned treatment.

Two, diagnostic criteria: recurrent painless hematuria, or the urinary tract infection symptom is arranged, late period visible dysuria and metastasis symptom, with shallow complexion, weak etc.Pathologic finding: can find transitional cell carcinoma, scale cancer or adenocarcinoma.The urine exfoliative cytology is checked positive.

Three, method of administration: be decocted in water for oral dose, 1 dose of every day, sub-service sooner or later, 10 days was 1 course of treatment, and drug withdrawal is 2 days between two courses of treatment.

Four, curative effect judging standard:

Short term effect: alleviation is meant irritation sign of bladder and tumor markers inspection complete obiteration fully, continues for 4 weeks at least, does not have new focus therebetween and occurs.

Part alleviate be meant with treat before compare all the perpendicular diameter products that can survey focus summation reduce and surpass 50%, continued for 4 weeks at least, do not have the appearance of new focus during this period.

Invalid: symptom does not have improvement or increases the weight of.

Five, therapeutic effect: short term effect: total remission rate 76.8%; Clinical disease: significantly improve 28 people, partly improve 33 people, do not have 3 people of improvement.Quality of life changes relatively: improve 42 examples, stablize 19 examples, 3 examples that descend, obvious effective rate 95.3%, inefficiency 4.68%.

Six, model case

1, chaste tree XX, man, 58 years old, in JIUYUE, 2009 bladder cancer postoperative is 4 months, in 4 cycles of chemotherapeutic bladder irrigation, occurs 1 week of painless hematuria again, companion's irritation sign of bladder was gone to a doctor in 1 day, and the urine exfoliative cytology is checked positive, the bladder ultrasound diagnosis, confirm recurrence, promptly obey totally 30 doses of 3 courses of treatment of this Chinese medicine, 1 dose of every day, 10 days was 1 course of treatment, no hematuria occurs after obeying 10 doses, the Radix Cirsii Japonici of stopping using.So far not recurrence.

2, Liu XX, the man, 62 years old, went to a doctor in November, 2009.Postoperative half a year, chemotherapy 6 cycles of one course of treatment.Intermittent painless property macroscopic blood 3 days appear, irritations sign of bladder such as frequent micturition, urgent micturition, dysurea 1 day, B ultrasonic: a small amount of hydrops of right kidney.Through 20 doses of 2 courses of treatment of clothes Chinese medicine of the present invention, remission.Drug withdrawal 1 month continues to obey for 1 course of treatment, so far recurrence.

3, Rhizoma Zingiberis Recens XX, the man, 47 years old, went to a doctor in January, 2010.The patient was diagnosed transitional cell carcinoma of bladder 3 months, row cell carcinoma excision 3 months, and in 3 cycles of chemotherapy, the patient is pernicious, vomit, can not take food, shallow complexion, and chemotherapy side effects such as malaise are heavier, can't tolerate.Stop chemotherapy after 1 week, gastrointestinal reaction disappears, and the patient requires to obey 1 week of drug withdrawal after 20 doses of 2 courses of treatment of Chinese medicine of the present invention, obeys for 2 courses of treatment again, so far recurrence.

Claims

1. Chinese medicine for the treatment of the recurrent bladder cancer is characterized in that it is made up of the component of following weight material medicine proportioning: Radix Codonopsis 10～14g, the Radix Astragali 9～12g, the Rhizoma Atractylodis Macrocephalae 10～15g, Radix Angelicae Sinensis 9～12g, the Radix Rehmanniae 10～15g, Coriolous Dersicolor (Fr.) Quel 8～12g, Radix Scutellariae 10～15g, Fructus Gardeniae 10～15g, Radix Cirsii Japonici 6～12g, Lasiosphaera Seu Calvatia 8～12g, Phellinus igniarius (L. ex Fr.) Quel. 6～10g, Nodus Nelumbinis Rhizomatis 8～12g, Rhizoma Alismatis 6～10g, Herba Lophatheri 10～15g, Radix Glycyrrhizae 6～10g.Be decocted in water for oral dose, 1 dose of every day, sub-service sooner or later, 10 days was 1 course of treatment

2. a kind of Chinese medicine for the treatment of the recurrent bladder cancer according to claim 1, its preferred side is Radix Codonopsis 12g, Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 10g, Radix Angelicae Sinensis 12g, Radix Rehmanniae 10g, Coriolous Dersicolor (Fr.) Quel 8g, Radix Scutellariae 10g, Fructus Gardeniae 12g, Radix Cirsii Japonici 8g, Lasiosphaera Seu Calvatia 10g, Phellinus igniarius (L. ex Fr.) Quel. 8g, Nodus Nelumbinis Rhizomatis 12g, Rhizoma Alismatis 6～10g, Herba Lophatheri 10g, Radix Glycyrrhizae 8g.Be decocted in water for oral dose, 1 dose of every day, sub-service sooner or later.10 days was 1 course of treatment.