CN102085331A - Drug for treating gout - Google Patents
Drug for treating gout Download PDFInfo
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- CN102085331A CN102085331A CN2009102527155A CN200910252715A CN102085331A CN 102085331 A CN102085331 A CN 102085331A CN 2009102527155 A CN2009102527155 A CN 2009102527155A CN 200910252715 A CN200910252715 A CN 200910252715A CN 102085331 A CN102085331 A CN 102085331A
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Abstract
The invention discloses a drug for treating gout, which is prepared by the following raw drugs on a weight basis: 20-40 parts of betelnut, 15-30 parts of epimedy, 10-20 parts of eupatorium, 15-30 parts of atractylodes, 10-20 parts of coix seeds, 5-15 parts of lumbricus, 25-40 parts of silkworm excrement, 15-30 parts of turmeric, 15-30 parts of Perilla Leaves, and 10-20 parts of evodia. The drug has good efficacy, little side effects, and good security in treating gout.
Description
Technical field
The present invention relates to the pharmaceutical preparations technology field, relate to the pharmaceutical composition for the treatment of gout or rather.
Background technology
Gout is meant that urate crystal is deposited on the various symptoms that tissue causes.Its clinical characters is that hyperuricemia and the gouty acute arthritis that causes are therefrom shown effect repeatedly, tophus deposition, tophus chronic arthritis and joint deformity etc.Often involve kidney and cause that chronic interstitial nephritis and uric acid renal calculus form.Primary disease with redness and swelling of joints, burning pain, outbreak repeatedly, joint motion is dumb is main clinical manifestation, belongs to Chinese medicine " arthromyodynia " category." treatise on blood trouble ": " gout, general numbness and hypoesthesia, limbs pain, modern name gout, Gu are said arthromyodynia ".
Gout has the sickness rate height, it is difficult to cure, characteristics such as outbreak repeatedly, and various complication make the patient suffering can't bear, and this disease is classified as one of 20th century mankind, ten big pertinacious diseases by the United Nations's health organization, also is the human second largest metabolism class disease that is only second to diabetes.The gout pilosity is born in middle-aged and elderly people, overweight people and brain worker.Along with the raising of people's living standard and the change of dietary structure, the sickness rate of gout rises just year by year, and the trend that becomes younger in addition.
The Western medicine that is used for the treatment of gout at present mainly contains: colchicine, Phenylbutazone or crovaril, indometacin, ibuprofen (ibvprofen, ibuprofen), piroxicam (piroxicanum), naproxen (naproxen congex), ACTH and prednisone etc.But can only stablize the state of an illness mostly, can not effect a radical cure gout; Also can cause serious adverse, cause the infringement of hepatic and renal function; Even treatment in the recent period effectively can not disease controlling be recurred, and can produce drug resistance and repellence, even the patient more or less can occur inevitably: leukopenia, cardiac function is impaired, hepatic and renal function is impaired, stimulating intestine and stomach system, aplastic anemia, cause complication such as diabetes.
Increasing expert thinks: from the organic conception of the traditional Chinese medical science, with the whole determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs of Chinese medicine, can yet be regarded as and treat another good footpath of gout; Not only the toxic and side effects of Chinese medicine itself significantly reduces, and can reduce the Western medicine dose, overcomes the huge toxic and side effects of for a long time taking Western medicine merely and being brought.But the Chinese patent medicine for the treatment of gout in the market is few, and curative effect lacks preferably especially, and the patient still can only stablize the state of an illness by taking the bigger Western medicine of toxic and side effects in a large number.
Summary of the invention
Purpose of the present invention just provides a kind of new Chinese medicine preparation for the treatment of gout, and this Drug therapy gout curative effect is better, and side effect is little, and safety is good.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of medicine for the treatment of gout, it is made by following raw materials in weight portion medicine:
Semen Arecae 20-40 part, Herba Epimedii 15-30 part, Herba Lycopi 10-20 part, Rhizoma Atractylodis 15-30 part,
Semen Coicis 10-20 part, Pheretima 5-15 part, silkworm excrement 25-40 part, Rhizoma Curcumae Longae 15-30 part,
Folium Perillae 15-30 part, Fructus Evodiae 10-20 part.
The weight proportion of each crude drug can be preferably in the said medicine:
Semen Arecae 25-35 part, Herba Epimedii 20-30 part, Herba Lycopi 10-20 part, Rhizoma Atractylodis 20-30 part,
Semen Coicis 10-20 part, Pheretima 10-15 part, silkworm excrement 25-35 part, Rhizoma Curcumae Longae 15-25 part,
Folium Perillae 15-25 part, Fructus Evodiae 10-20 part.
The weight proportion of each crude drug is more preferably in the said medicine:
Semen Arecae 25-30 part, Herba Epimedii 25-30 part, Herba Lycopi 15-20 part, Rhizoma Atractylodis 25-30 part,
Semen Coicis 15-20 part, Pheretima 10-15 part, silkworm excrement 25-30 part, Rhizoma Curcumae Longae 15-20 part,
Folium Perillae 15-20 part, Fructus Evodiae 10-15 part.
Weight proportion the best of each crude drug is in the said medicine:
30 parts of Semen Arecaes, 28 parts of Herba Epimedii, 15 parts of Herba Lycopi, 28 parts of Rhizoma Atractylodis,
15 parts of Semen Coiciss, 15 parts of Pheretimas, 25 parts of silkworm excrements, 18 parts in Rhizoma Curcumae Longae,
18 parts of Folium Perillae, 12 parts of Fructus Evodiaes.
The medicine of above-mentioned treatment gout can be made the medicine of any one suitable on pharmaceutics dosage form with each crude drug after treatment according to the formulation method of routine, can preferably make tablet, capsule, granule, oral liquid, drop pill etc.
According to the needs of the various drug forms of preparation, medicine of the present invention also can add suitable pharmaceutic adjuvant such as filler, disintegrating agent, binding agent, lubricant etc. in preparation process.
The used various raw medicinal materials of the present invention are the Chinese crude drug that meets national drug standards regulation.
Compared with prior art, the invention has the beneficial effects as follows: above 10 flavor Chinese medicine composition are not used for the treatment of together the technical scheme of gout in (1) prior art, medicine of the present invention provides a kind of new selection for the gout patient; Show through pharmacodynamics test and toxicological test that (2) it is better that medicine of the present invention is used for the treatment of the gout curative effect, and toxic and side effects is little, safety is good.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
Embodiment 1
The present embodiment medicine is made by following materials of weight proportions medicine:
30 parts of Semen Arecaes, 28 parts of Herba Epimedii, 15 parts of Herba Lycopi, 28 parts of Rhizoma Atractylodis,
15 parts of Semen Coiciss, 15 parts of Pheretimas, 25 parts of silkworm excrements, 18 parts in Rhizoma Curcumae Longae,
18 parts of Folium Perillae, 12 parts of Fructus Evodiaes.
Embodiment 2
The present embodiment medicine is made by following materials of weight proportions medicine:
20 parts of Semen Arecaes, 20 parts of Herba Epimedii, 15 parts of Herba Lycopi, 30 parts of Rhizoma Atractylodis,
20 parts of Semen Coiciss, 10 parts of Pheretimas, 25 parts of silkworm excrements, 20 parts in Rhizoma Curcumae Longae,
20 parts of Folium Perillae, 10 parts of Fructus Evodiaes.
Embodiment 3
The present embodiment medicine is made by following materials of weight proportions medicine:
25 parts of Semen Arecaes, 15 parts of Herba Epimedii, 20 parts of Herba Lycopi, 15 parts of Rhizoma Atractylodis,
10 parts of Semen Coiciss, 5 parts of Pheretimas, 40 parts of silkworm excrements, 30 parts in Rhizoma Curcumae Longae,
25 parts of Folium Perillae, 20 parts of Fructus Evodiaes.
Embodiment 4
The present embodiment medicine is made by following materials of weight proportions medicine:
40 parts of Semen Arecaes, 30 parts of Herba Epimedii, 10 parts of Herba Lycopi, 20 parts of Rhizoma Atractylodis,
15 parts of Semen Coiciss, 15 parts of Pheretimas, 30 parts of silkworm excrements, 25 parts in Rhizoma Curcumae Longae,
15 parts of Folium Perillae, 15 parts of Fructus Evodiaes.
Embodiment 5
The present embodiment medicine is made by following materials of weight proportions medicine:
35 parts of Semen Arecaes, 25 parts of Herba Epimedii, 18 parts of Herba Lycopi, 25 parts of Rhizoma Atractylodis,
22 parts of Semen Coiciss, 20 parts of Pheretimas, 35 parts of silkworm excrements, 15 parts in Rhizoma Curcumae Longae,
30 parts of Folium Perillae, 10 parts of Fructus Evodiaes.
The various embodiments described above medicine, all can be according to the formulation method of routine, each crude drug of corresponding weight proportion after methods such as the extraction of routine and purification are handled, is made the medicine of required dosage form again, as: tablet, capsule, granule, oral liquid, drop pill etc.
In addition, according to the needs of the various drug forms of preparation, the various embodiments described above medicine also can add suitable pharmaceutic adjuvant such as starch, dextrin, sucrose, magnesium stearate, microcrystalline cellulose, hydroxypropyl emthylcellulose, vegetable oil, lecithin, Polyethylene Glycol, propylene glycol, ethyl hydroxybenzoate etc. in preparation process.
Claims (5)
1. medicine for the treatment of gout, it is made by following raw materials in weight portion medicine:
Semen Arecae 20-40 part, Herba Epimedii 15-30 part, Herba Lycopi 10-20 part, Rhizoma Atractylodis 15-30 part,
Semen Coicis 10-20 part, Pheretima 5-15 part, silkworm excrement 25-40 part, Rhizoma Curcumae Longae 15-30 part,
Folium Perillae 15-30 part, Fructus Evodiae 10-20 part.
2. according to the medicine of claim 1, it is characterized in that the weight proportion of each crude drug in the described medicine is:
Semen Arecae 25-35 part, Herba Epimedii 20-30 part, Herba Lycopi 10-20 part, Rhizoma Atractylodis 20-30 part,
Semen Coicis 10-20 part, Pheretima 10-15 part, silkworm excrement 25-35 part, Rhizoma Curcumae Longae 15-25 part,
Folium Perillae 15-25 part, Fructus Evodiae 10-20 part.
3. according to the medicine of claim 2, it is characterized in that the weight proportion of each crude drug in the described medicine is:
Semen Arecae 25-30 part, Herba Epimedii 25-30 part, Herba Lycopi 15-20 part, Rhizoma Atractylodis 25-30 part,
Semen Coicis 15-20 part, Pheretima 10-15 part, silkworm excrement 25-30 part, Rhizoma Curcumae Longae 15-20 part,
Folium Perillae 15-20 part, Fructus Evodiae 10-15 part.
4. according to the medicine of claim 3, it is characterized in that the weight proportion of each crude drug in the described medicine is:
30 parts of Semen Arecaes, 28 parts of Herba Epimedii, 15 parts of Herba Lycopi, 28 parts of Rhizoma Atractylodis,
15 parts of Semen Coiciss, 15 parts of Pheretimas, 25 parts of silkworm excrements, 18 parts in Rhizoma Curcumae Longae,
18 parts of Folium Perillae, 12 parts of Fructus Evodiaes.
5. according to each described medicine in the claim 1 to 4, it is characterized in that the dosage form of said medicine is selected from tablet, capsule, granule, oral liquid, drop pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102527155A CN102085331A (en) | 2009-12-02 | 2009-12-02 | Drug for treating gout |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102527155A CN102085331A (en) | 2009-12-02 | 2009-12-02 | Drug for treating gout |
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| Publication Number | Publication Date |
|---|---|
| CN102085331A true CN102085331A (en) | 2011-06-08 |
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| CN2009102527155A Pending CN102085331A (en) | 2009-12-02 | 2009-12-02 | Drug for treating gout |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735630A (en) * | 2013-12-25 | 2014-04-23 | 柳州市中医院 | Traditional Chinese medicine for treating gout |
-
2009
- 2009-12-02 CN CN2009102527155A patent/CN102085331A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735630A (en) * | 2013-12-25 | 2014-04-23 | 柳州市中医院 | Traditional Chinese medicine for treating gout |
| CN103735630B (en) * | 2013-12-25 | 2016-03-30 | 柳州市中医院 | A kind of Chinese medicine for the treatment of gout |
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Addressee: Li Xiong Document name: Notification of Publication of the Application for Invention |
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Application publication date: 20110608 |