CN102085232A - Astragalus dispersible tablets - Google Patents
Astragalus dispersible tablets Download PDFInfo
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- CN102085232A CN102085232A CN2009102164861A CN200910216486A CN102085232A CN 102085232 A CN102085232 A CN 102085232A CN 2009102164861 A CN2009102164861 A CN 2009102164861A CN 200910216486 A CN200910216486 A CN 200910216486A CN 102085232 A CN102085232 A CN 102085232A
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- radix astragali
- astragalus
- dispersible tablets
- magnesium stearate
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to astragalus dispersible tablets, and belongs to the field of traditional Chinese medicaments. In order to solve a technical problem, the invention provides the astragalus dispersible tablets with high bioavailability. The astragalus dispersible tablets are prepared from the following raw material medicaments and auxiliary materials in part by weight: 50 to 100 parts of ethanol extract of astragalus, 50 to 120 parts of microcrystalline cellulose, 50 to 90 parts of carboxymethyl starch sodium, 20 to 35 parts of cross-linked polyethylene pyrrolidone and 3 to 8 parts of magnesium stearate. The astragalus dispersible tablets have high bioavailability and quick effect, provides a new option for the field and has wide application prospect.
Description
Technical field
Radix Astragali dispersible tablet of the present invention belongs to the field of Chinese medicines.
Background technology
Radix Astragali Astragalus membranaceus (Fisch.) Bunge contains sucrose, glucuronic acid, astragalus polysaccharides A, B, C, D, lymphatic temperament, several amino acids, bitter principle, Radix Astragali saponin, choline, folic acid, flavane chemical compound and contain various trace elements such as selenium, silicon, zinc, cobalt, copper, molybdenum.Be used for invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.The Radix Astragali main dosage form at present is a Radix Astragali oral liquid, but the bioavailability of Radix Astragali oral liquid is low, and onset is slow, can't satisfy patient's needs.
Summary of the invention
Technical problem to be solved by this invention provides the higher Radix Astragali dispersible tablet of a kind of bioavailability.
Radix Astragali dispersible tablet of the present invention is to be prepared from by following materials of weight proportions medicine and adjuvant: 50 ~ 100 parts of Radix Astragali ethanol extractions, 50 ~ 120 parts of microcrystalline Cellulose, 50 ~ 90 parts of carboxymethyl starch sodium, 20 ~ 35 parts of crospolyvinylpyrrolidone, 3 ~ 8 parts of magnesium stearate.
Wherein, above-mentioned Radix Astragali ethanol extraction can directly adopt commercially available Radix Astragali ethanol extraction.Also can make through ethanol extraction with the Radix Astragali.
Further, Radix Astragali dispersible tablet of the present invention preferably is prepared from by following materials of weight proportions medicine and adjuvant: 70 ~ 90 parts of Radix Astragali ethanol extractions, 75 ~ 110 parts of microcrystalline Cellulose, 40 ~ 70 parts of carboxymethyl starch sodium, 25 ~ 30 parts of crospolyvinylpyrrolidone, 3 ~ 7 parts of magnesium stearate.
Further, Radix Astragali dispersible tablet of the present invention most preferably is prepared from by following materials of weight proportions medicine and adjuvant: 85 parts of Radix Astragali ethanol extractions, 90 parts of microcrystalline Cellulose, 60 parts of carboxymethyl starch sodium, 27 parts of crospolyvinylpyrrolidone, 5 parts of magnesium stearate.
Radix Astragali dispersible tablet of the present invention can adopt following method to be prepared from: press above-mentioned weight proportion with Radix Astragali ethanol extraction, microcrystalline Cellulose, carboxymethyl starch sodium and crospolyvinylpyrrolidone mixing, the percent by volume that adds wetting amount is 75 ~ 95% ethanol, granulate, add magnesium stearate then, tabletting, promptly.
Radix Astragali dispersible tablet of the present invention, its bioavailability height, rapid-action, for this area provides a kind of new selection, have broad application prospects.
The specific embodiment
Below in conjunction with embodiment the specific embodiment of the present invention is further described, does not therefore limit the present invention among the described scope of embodiments.
The preparation of embodiment 1 Radix Astragali dispersible tablet of the present invention
With Radix Astragali ethanol extraction (commercially available) 50g, microcrystalline Cellulose 50g, carboxymethyl starch sodium 50g and crospolyvinylpyrrolidone 20g mixing, 80% the ethanol that adds the wetting amount percent by volume and be is granulated, and adds magnesium stearate 3g then, tabletting makes Radix Astragali dispersible tablet of the present invention.
The preparation of embodiment 2 Radix Astragali dispersible tablets of the present invention
With Radix Astragali ethanol extraction (commercially available) 100g, microcrystalline Cellulose 120g, carboxymethyl starch sodium 90g and crospolyvinylpyrrolidone 30g mixing, 85% the ethanol that adds the wetting amount percent by volume and be is granulated, and adds magnesium stearate 7g then, tabletting makes Radix Astragali dispersible tablet of the present invention.
The preparation of embodiment 3 Radix Astragali dispersible tablets of the present invention
With Radix Astragali ethanol extraction (commercially available) 85g, microcrystalline Cellulose 90g, carboxymethyl starch sodium 60g and crospolyvinylpyrrolidone 27g mixing, 95% the ethanol that adds the wetting amount percent by volume and be is granulated, and adds magnesium stearate 5g then, tabletting makes Radix Astragali dispersible tablet of the present invention.
Claims (3)
1. Radix Astragali dispersible tablet, it is characterized in that: be prepared from: 50 ~ 100 parts of Radix Astragali ethanol extractions, 50 ~ 120 parts of microcrystalline Cellulose, 50 ~ 90 parts of carboxymethyl starch sodium by following materials of weight proportions medicine and adjuvant, 20 ~ 35 parts of crospolyvinylpyrrolidone, 3 ~ 8 parts of magnesium stearate.
2. Radix Astragali dispersible tablet according to claim 1, it is characterized in that: be prepared from: 70 ~ 90 parts of Radix Astragali ethanol extractions by following materials of weight proportions medicine and adjuvant, 75 ~ 110 parts of microcrystalline Cellulose, 40 ~ 70 parts of carboxymethyl starch sodium, 25 ~ 30 parts of crospolyvinylpyrrolidone, 3 ~ 7 parts of magnesium stearate.
3. Radix Astragali dispersible tablet according to claim 1, it is characterized in that: be prepared from: 85 parts of Radix Astragali ethanol extractions, 90 parts of microcrystalline Cellulose, 60 parts of carboxymethyl starch sodium by following materials of weight proportions medicine and adjuvant, 27 parts of crospolyvinylpyrrolidone, 5 parts of magnesium stearate.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2009102164861A CN102085232A (en) | 2009-12-02 | 2009-12-02 | Astragalus dispersible tablets |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN2009102164861A CN102085232A (en) | 2009-12-02 | 2009-12-02 | Astragalus dispersible tablets |
Publications (1)
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CN102085232A true CN102085232A (en) | 2011-06-08 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN2009102164861A Pending CN102085232A (en) | 2009-12-02 | 2009-12-02 | Astragalus dispersible tablets |
Country Status (1)
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CN (1) | CN102085232A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103704710A (en) * | 2013-12-31 | 2014-04-09 | 陈慧婷 | Chinese yam and pericarpium citri reticulatae viride dispersible tablet and preparation method thereof |
-
2009
- 2009-12-02 CN CN2009102164861A patent/CN102085232A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103704710A (en) * | 2013-12-31 | 2014-04-09 | 陈慧婷 | Chinese yam and pericarpium citri reticulatae viride dispersible tablet and preparation method thereof |
CN103704710B (en) * | 2013-12-31 | 2016-01-27 | 陈慧婷 | A kind of Chinese yam pericarpium citri reticulatae viride dispersible tablet and preparation method |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
DD01 | Delivery of document by public notice |
Addressee: Huang Xiaochuan Document name: Notification of Passing Preliminary Examination of the Application for Invention |
|
C06 | Publication | ||
PB01 | Publication | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110608 |