CN102083964B - 与基于细胞的疗法相关的材料和方法 - Google Patents
与基于细胞的疗法相关的材料和方法 Download PDFInfo
- Publication number
- CN102083964B CN102083964B CN2009801260075A CN200980126007A CN102083964B CN 102083964 B CN102083964 B CN 102083964B CN 2009801260075 A CN2009801260075 A CN 2009801260075A CN 200980126007 A CN200980126007 A CN 200980126007A CN 102083964 B CN102083964 B CN 102083964B
- Authority
- CN
- China
- Prior art keywords
- cells
- positive
- cell
- negative
- pancreatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5073—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5209808P | 2008-05-09 | 2008-05-09 | |
| US61/052,098 | 2008-05-09 | ||
| PCT/GB2009/001149 WO2009136168A1 (en) | 2008-05-09 | 2009-05-08 | Materials and methods relating to cell based therapies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102083964A CN102083964A (zh) | 2011-06-01 |
| CN102083964B true CN102083964B (zh) | 2013-06-12 |
Family
ID=40935531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009801260075A Expired - Fee Related CN102083964B (zh) | 2008-05-09 | 2009-05-08 | 与基于细胞的疗法相关的材料和方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20110158961A1 (https=) |
| EP (1) | EP2283115A1 (https=) |
| JP (1) | JP2011519574A (https=) |
| CN (1) | CN102083964B (https=) |
| WO (1) | WO2009136168A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2845280A1 (en) | 2010-08-13 | 2012-02-16 | Paul Shiels | Therapeutic uses of microvesicles and related micrornas |
| EP2864473B1 (en) * | 2012-06-26 | 2019-08-21 | Seraxis, Inc. | Stem cells and pancreatic cells useful for the treatment of insulin-dependent diabetes mellitus |
| WO2014091373A1 (en) | 2012-12-11 | 2014-06-19 | The University Court Of The University Of Glasgow | Cellular and molecular therapies for peripheral vascular disease |
| CN116121189A (zh) * | 2016-03-30 | 2023-05-16 | 阿斯特利亚斯生物治疗股份公司 | 少突胶质细胞祖细胞组合物 |
| WO2018034023A1 (ja) * | 2016-08-18 | 2018-02-22 | 北海道公立大学法人札幌医科大学 | 寿命延長剤 |
| WO2018187298A1 (en) | 2017-04-04 | 2018-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Preparation, expansion, and uses of adult pluripotent stem cells |
| US20190085296A1 (en) * | 2017-09-20 | 2019-03-21 | Sergio Mora | Method of expansion of human pancreas progenitor cells from stem cells using feeder-conditioned media |
| IL281628B2 (en) | 2018-09-19 | 2025-06-01 | Lineage Cell Therapeutics Inc | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| CN112739208A (zh) | 2018-09-21 | 2021-04-30 | 艾普斯丹医疗公司 | 人类多能成体干细胞 |
| WO2020154533A1 (en) | 2019-01-23 | 2020-07-30 | Asterias Biotherapeutics, Inc. | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
| CN113710285A (zh) * | 2019-03-26 | 2021-11-26 | 宾州研究基金会 | 用于治疗癌症的方法和材料 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6878543B1 (en) * | 1999-10-25 | 2005-04-12 | Nsgene Sa | Cultures of GFAP+ nestin+ cells that differentiate to neurons |
| WO2006120476A1 (en) * | 2005-05-13 | 2006-11-16 | The University Court Of The University Of Glasgow | Materials and methods relating to cell based therapies |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020012653A1 (en) * | 1997-12-19 | 2002-01-31 | Kevin Pang | Bile duct progenitor cells and methods of use |
| CA2460985C (en) * | 2001-09-20 | 2016-01-05 | Anticancer, Inc. | Nestin-expressing hair follicle stem cells |
| US20040029269A1 (en) * | 2002-05-07 | 2004-02-12 | Goldman Steven A | Promoter-based isolation, purification, expansion, and transplantation of neuronal progenitor cells, oligodendrocyte progenitor cells, or neural stem cells from a population of embryonic stem cells |
-
2009
- 2009-05-08 CN CN2009801260075A patent/CN102083964B/zh not_active Expired - Fee Related
- 2009-05-08 JP JP2011507987A patent/JP2011519574A/ja active Pending
- 2009-05-08 US US12/991,878 patent/US20110158961A1/en not_active Abandoned
- 2009-05-08 EP EP09742364A patent/EP2283115A1/en not_active Withdrawn
- 2009-05-08 WO PCT/GB2009/001149 patent/WO2009136168A1/en not_active Ceased
-
2013
- 2013-05-21 US US13/898,625 patent/US20130280219A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6878543B1 (en) * | 1999-10-25 | 2005-04-12 | Nsgene Sa | Cultures of GFAP+ nestin+ cells that differentiate to neurons |
| WO2006120476A1 (en) * | 2005-05-13 | 2006-11-16 | The University Court Of The University Of Glasgow | Materials and methods relating to cell based therapies |
Non-Patent Citations (1)
| Title |
|---|
| Karen L Seeberger et al.Expansion of mesenchymal stem cells from human pancreatic ductal epithelium.《Laboratory Investigation》.2006,第86卷141-153. * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009136168A1 (en) | 2009-11-12 |
| US20130280219A1 (en) | 2013-10-24 |
| EP2283115A1 (en) | 2011-02-16 |
| US20110158961A1 (en) | 2011-06-30 |
| HK1157814A1 (en) | 2012-07-06 |
| CN102083964A (zh) | 2011-06-01 |
| JP2011519574A (ja) | 2011-07-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102083964B (zh) | 与基于细胞的疗法相关的材料和方法 | |
| Oshima et al. | Isolation of mouse pancreatic ductal progenitor cells expressing CD133 and c-Met by flow cytometric cell sorting | |
| Suzuki et al. | Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting | |
| Hisatomi et al. | Flow cytometric isolation of endodermal progenitors from mouse salivary gland differentiate into hepatic and pancreatic lineages | |
| Yeung et al. | Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines | |
| Xie et al. | Human bone marrow mesenchymal stem cells differentiate into insulin-producing cells upon microenvironmental manipulation in vitro | |
| Dabeva et al. | Hepatic stem cells and liver repopulation | |
| Hoppo et al. | Thy1‐positive mesenchymal cells promote the maturation of CD49f‐positive hepatic progenitor cells in the mouse fetal liver | |
| US10093895B2 (en) | Hepatic stellate cell precursors and methods of isolating same | |
| Lin et al. | Characterization of pancreatic stem cells derived from adult human pancreas ducts by fluorescence activated cell sorting | |
| JP2011519574A5 (https=) | ||
| EP1896571B1 (en) | Materials and methods relating to cell based therapies | |
| Baek et al. | Autonomous isolation, long‐term culture and differentiation potential of adult salivary gland‐derived stem/progenitor cells | |
| Lo Nigro et al. | Amnion-derived mesenchymal stromal/stem cell paracrine signals potentiate human liver organoid differentiation: translational implications for liver regeneration | |
| Meivar-Levy et al. | Human liver cells expressing albumin and mesenchymal characteristics give rise to insulin‐producing cells | |
| Petrakova et al. | Comparative analysis reveals similarities between cultured submandibular salivary gland cells and liver progenitor cells | |
| Cancedda et al. | The Phoenix of stem cells: pluripotent cells in adult tissues and peripheral blood | |
| CN116585354A (zh) | 胰腺干细胞及其用途 | |
| Stevenson et al. | Isolation, characterization, and differentiation of thy1. 1-sorted pancreatic adult progenitor cell populations | |
| US20050084964A1 (en) | Stem cells originating in salivary duet epithelial cells and use thereof | |
| Lan et al. | Islet-like clusters derived from skeletal muscle-derived stem/progenitor cells for autologous transplantation to control type 1 diabetes in mice | |
| Xiao et al. | Establishing a human pancreatic stem cell line and transplanting induced pancreatic islets to reverse experimental diabetes in rats | |
| Wang et al. | Differentiation of CD24− pancreatic ductal cell‐derived cells into insulin‐secreting cells | |
| JP4147306B2 (ja) | 唾液腺由来の内胚葉系細胞および外胚葉系細胞の双方に分化可能な未分化な多分化能を有する新規細胞およびその細胞の調製方法 | |
| HK1157814B (en) | Materials and methods relating to cell based therapies |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1157814 Country of ref document: HK |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1157814 Country of ref document: HK |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130612 Termination date: 20150508 |
|
| EXPY | Termination of patent right or utility model |