CN102078532A - Chinese medicine composition for treating cardiac cancer - Google Patents
Chinese medicine composition for treating cardiac cancer Download PDFInfo
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- CN102078532A CN102078532A CN 201110022842 CN201110022842A CN102078532A CN 102078532 A CN102078532 A CN 102078532A CN 201110022842 CN201110022842 CN 201110022842 CN 201110022842 A CN201110022842 A CN 201110022842A CN 102078532 A CN102078532 A CN 102078532A
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Abstract
The invention relates to a Chinese medicine composition for treating cardiac cancer, which is prepared from the following raw materials in parts by weight: 2-4 parts of herba polygoni avicularis, 0.8-1.5 parts of plantain herb, 0.8-1.2 parts of moxa stick, 0.8-1.2 parts of common fennel, 1.5-2.5 parts of cogongrass rhizome and 0.8-1.2 parts of rhizoma polygonati. After all raw materials are mixed according to the weight part and grinded into powders which can be directly orally taken. The invention has the advantages of remarkable curative effect, low cost, simple treating manner, convenience for medicine administration and almost non-toxic and side effects; in addition, the effective rate of the traditional Chinese medicine composition is more than 92% through the clinical observation.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of carcinoma of gastric cardia.
Background technology
Carcinoma of gastric cardia is to occur in stomachus cardiacus, just the adenocarcinoma in about 2cm scope under the esophagus and stomach boundary line.It is the specific type of gastric cancer, should distinguish with the distal esophagus cancer.But the gastric cancer with other positions is different again for it, has anatomy histological characteristic and the clinical manifestation of oneself, unique diagnosis and Therapeutic Method and relatively poor surgical intervention effect.In China, the mortality rate of carcinoma of gastric cardia and sickness rate rank among the best in all kinds of malignant tumor.Have data to show, the mortality rate of carcinoma of gastric cardia accounts for about 12% of general mortality rate, and local hotspot can reach 20%.The clinical onset rate had the trend of continuous rising in recent years, serious threat human beings'health and life.
The initial symptom of carcinoma of gastric cardia has two kinds of situations: if taken place by the bottom esophagus, then already very narrow cardia will be narrower, therefore, occurs easily and the very similar symptom of esophageal carcinoma; If betide body of stomach, or the stomach head side, then there is not subjective symptoms haply during the initial stage, therefore, also be difficult to diagnosis.Food by the time peculiar sense, severe pain are arranged, a sense of obstruction are arranged, slight pit of the stomach pain.Above symptom can be felt when swallowing, and when gulping down harder food, feel as " rub-a-dub " directly fall one in the stomach, more responsive when especially drinking heat or cold liquid, wherein initial a bite feels the most obvious.If suffer from cancer, in a single day above-mentioned symptom occurs so, will exist always.As for the similar non-cancer patient of symptom, then these symptoms will be flickered, and do not have regularly, and the weight of symptom is also inequality.Another initial symptom of carcinoma of gastric cardia is a upper gastrointestinal hemorrhage, shows as hematemesis or tarry stool.According to the hemorrhage order of severity or follow collapse shock, or the performance anemia.The incidence rate of this kind situation accounts for patient's 5%.Obstruct the symptom of choking owing to lack, this kind patient is a digestive ulcerative bleeding by mistaken diagnosis easily, by abdominal surgery doctor operation, makes a definite diagnosis soon in the art.Exactly because also majority is an emergency operation, each side is prepared abundant inadequately, and this class patient postoperative complication incidence rate and mortality rate are all higher, and curative effect is bad.
For a long time, operative treatment is the first-selection treatment of the carcinoma of gastric cardia of generally acknowledging, but the expense height of operative treatment is very big to injury of human, and postoperative recurrence rate height, and survival rate is low.In addition, because its histology is adenocarcinoma or mucinous adenocarcinoma, the radiotherapy nearly unavailable, chemical therapeutic effect is also very little.
Summary of the invention
For overcoming the prior art deficiency, the object of the invention be to provide a kind of evident in efficacy, with low cost, medication convenient, the Chinese medicine composition of the treatment carcinoma of gastric cardia of almost non-toxic side effect.
For achieving the above object, the present invention adopts following technical scheme:
A kind of Chinese medicine composition for the treatment of carcinoma of gastric cardia, it makes 2～4 parts of: Herba Polygoni Avicularis, 0.8～1.5 part of Herba Plantaginis, 0.8～1.2 part of moxa roll, 0.8～1.2 part of Fructus Foeniculi, 1.5～2.5 parts of Rhizoma Imperataes, 0.8～1.2 part of Rhizoma Polygonati by following weight portion crude drug.
Further, the parts by weight of described each crude drug are preferably 3 parts of: Herba Polygoni Avicularis, 1 part of Herba Plantaginis, 1 part of moxa roll, 1 part of Fructus Foeniculi, 2 parts of Rhizoma Imperataes, 1 part of Rhizoma Polygonati.
The cylindrical long paper that moxa roll of the present invention is to use cotton paper parcel Folium Artemisiae Argyi to make, Folium Artemisiae Argyi is also referred to as Folium Artemisiae Argyi, Folium Artemisiae Argyi etc.
Chinese medicine composition of the present invention can be prepared into any oral formulations commonly used according to the method for Chinese medicinal of routine, and described oral formulations can be pill, capsule, tablet, powder, granule or oral liquid.
Make powder as grinding to form the end after each crude drug mixing that can get above-mentioned weight portion in proportion, it is standby to bottle.During use, the powder after grinding directly can be taken, 4 times on the one, about a 2.25g, warm water takes.30 days is a course of treatment, and general half can fully recover to 1 year.
The Chinese medicine determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, the mutual junction type of phlegm stagnancy: sputum, fat, the greasy fur of body of the tongue are blocked, vomitted to performance based on feed; Type of blood-stasis obstructing in the interior: performance is with the unfavorable pain of swallowing of taking food, hematemesis, melena, xerostomia, epigastric oppression, purplish tongue, stringy pulse or puckery; The deficient type of healthy energy: with anemia, weak, cardiopalmus, perspiration, anorexia etc. is main performance.The present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment carcinoma of gastric cardia, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical the accent, emergency is taken in concurrently, filter out the Chinese medicine composition of " heat-clearing and toxic substances removing, strengthening vital QI to eliminate pathogenic factors, blood circulation promoting and blood stasis dispelling, softening the hard mass tumor ", according to the theory of Chinese medical science prescription, formulated according to certain parts by weight.The property of medicine and the pharmacological action of Chinese medicine composition of the present invention are as follows:
Herba Polygoni Avicularis, another name pig wheatgrass, common knotgrass etc. are the herb of Polygonaceae annual herb Zhi Wu Herba Polygoni Avicularis, bitter in the mouth is slightly cold, and returns urinary bladder channel, function with cure mainly: inducing diuresis for treating stranguria syndrome, parasite killing, antipruritic.Be used for the bladder pyretic stranguria, oliguria with reddish urine drenches the puckery pain of drop, skin eczema, pudendal pruritus leukorrhagia.Herba Plantaginis, sweet in flavor and cold in property.Return liver, kidney, lung, small intestine meridian.Function with cure mainly: clearing away heat and promoting diuresis; Eliminate the phlegm; Removing heat from blood; Detoxifcation.Be used for the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, dysuria, laryngopharynx swelling and pain; Carbuncle sore tumefacting virus.Folium Artemisiae Argyi, property suffering, hardship, temperature; Slightly poisonous.Return the liver,spleen,kidney warp.Cure mainly dispersing cold for relieving pain, warming the meridian for stopping bleeding.Be used for few abdomen cold type of pain, coldness and unbalance in meridians is spitted blood epistaxis; The external treatment skin pruritus, decortication.《 Lv Cliff rock book on Chinese herbal medicine " record: control throat and close the heap soil or fertilizer over and around the roots of pain heat, diet has harm person, smashes the juice filling and gargles." detailed outline ": warming middle-JIAO, by cold, dehumidifying." book on Chinese herbal medicine just ": ward off the wind and cold alunite, subtertian malaria.Fructus Foeniculi, property is flat, invigorates blood circulation, promoting the circulation of QI.Dispelling cold by warming the meridian, qi and blood circulation promotion is by cold-damp.Rhizoma Imperatae also claims root of couch grass, and is for the dry rhizome of grass Herba Imperatae, sweet in flavor and cold in property.Return lung, stomach, urinary bladder channel.Function with cure mainly: cooling blood for hemostasis, clearing away heat and promoting diuresis.Be used for heat in blood and spit blood epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria, acute nephritis edema.Rhizoma Polygonati is called native Ganoderma, and nature and flavor are sweet flat, return spleen, lung kidney channel.Function with cure mainly: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.Be used for weakness of the spleen and stomach, fatigue and asthenia, the xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Above-mentioned all medicine compatibilities are reasonable, complement each other, each crude drug is coordinated can at utmost bring into play drug effect mutually together, can strengthen the effect of medicine heat-clearing and toxic substances removing, strengthening vital QI to eliminate pathogenic factors, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, anticancer analgetic, regulating liver and qi, thereby can effectively treat carcinoma of gastric cardia.In addition, traditional Chinese medicine composition for treating means of the present invention are simple, medication convenient, side effect evident in efficacy, with low cost, almost non-toxic.
The carcinoma of gastric cardia diagnosis mainly contains the inspection of X line canel barium meal contrast examination clinically, endoscopy, and ultrasound diagnosis, several diagnostic methods commonly used such as CT examination, wherein the inspection of X line canel barium meal contrast examination is a carcinoma of gastric cardia important diagnostic method.The early symptom performance of carcinoma of gastric cardia is as follows: feeling of distension and oppression or mild pain behind (1) breastbone.This symptom is not continue to take place, but intermittent or increase the weight of during feed after fatigue and fast.Foreign body sensation when (2) swallowing food.Food (particularly stiff food) may produce a kind of foreign body sensation through diseased region (pathological changes is very little) in the pharynx food process, and often is fixed on a position, and the patient who has describes picture the not sensation of intact thing of eternal pharynx.Slight and be and ask the generation of having a rest property because of symptom, also easily neglected by patient.(3) eat and stagnate or the pause and transition in rhythm or melody sense, the sensation of stagnating pause and transition in rhythm or melody at certain position is for the moment seemingly arranged when promptly patient swallows food, this situation is non-standing also, only just obviously gets up gradually after pathological development.(4) feeling of distension and oppression over the chest or constriction, and often with the bottleneck throat dry sensation.Patient main suit's chest has a kind of stifling phenomenon all the time, seemingly has an object to stop up, and makes the intrathoracic sensation that is deflation, and is particularly evident when swallowing food, but do not influence orthobiosis and work.(5) precordial region, xiphoid-process are down or epigastrium is glutted and hypodynia, and be comparatively obvious when advancing xerophagia, but also be not all can take place at every turn and be intermittent.This situation is the early symptom of carcinoma of gastric cardia often.Above carcinoma of gastric cardia early symptom generally all will continue more than 3 months.To often, be carcinoma of gastric cardia middle and advanced stage symptom just when persistence takes place, treatment difficulty has at this moment just strengthened many.Carcinoma of gastric cardia mid-term symptom between early symptom and late period symptom, be and carry out sexual development.Mid-term carcinoma of gastric cardia common sympton, the moderate cachexia is arranged, anemia, edema, the whole body scorpion that declines, vitals transfer such as liver, lung, brain and abdominal cavity, pelvic cavity shift, and cause basin blood, ascites vegetables bloody ascites, liver failure, stupor, digestive tract blocks etc.The visible anemia of middle and advanced stage patient, low plasma protein, become thin even dewater.If enclosed mass, hepatomegaly, sign of ascites, pelvic swelling thing (anus touch) appear in abdominal part, all are the symbol that is unsuitable for performing the operation.Late case the lasting dull pain of upper abdomen and back also can occur except dysphagia, shows after carcinoma has involved peritoneum such as pancreas to organize, and be contraindication for operation.Except the symptom of esophageal carcinoma, also have the symptomatology of gastric cancer as follows: (1) swallows obstacle (when drinking water also can); (2) epigastrium has sense of heaviness; (3) stomach can be bitterly; (4) feel sick, vomit; (5) people becomes thin gradually.
The specific embodiment
Below in conjunction with embodiment technical scheme of the present invention is described further, but protection scope of the present invention is not limited thereto.
Embodiment 1:
A kind of Chinese medicine composition for the treatment of carcinoma of gastric cardia, it makes: Herba Polygoni Avicularis 3g, Herba Plantaginis 1g, moxa roll 1 g, Fructus Foeniculi 1 g, Rhizoma Imperatae 2 g, Rhizoma Polygonati 1 g by following crude drug.
Embodiment 2:
A kind of Chinese medicine composition for the treatment of carcinoma of gastric cardia, it makes: Herba Polygoni Avicularis 2.2 g, Herba Plantaginis 0.8g, moxa roll 1.2g, Fructus Foeniculi 0.9g, Rhizoma Imperatae 1.5g, Rhizoma Polygonati 1.2g by following crude drug.
Embodiment 3:
A kind of Chinese medicine composition for the treatment of carcinoma of gastric cardia, it makes: Herba Polygoni Avicularis 4g, Herba Plantaginis 1.2g, moxa roll 0.9g, Fructus Foeniculi 1.2g, Rhizoma Imperatae 2.3g, Rhizoma Polygonati 0.9g by following crude drug.
Embodiment 4:
A kind of Chinese medicine composition for the treatment of carcinoma of gastric cardia, it makes: Herba Polygoni Avicularis 3.5g, Herba Plantaginis 1.5g, moxa roll 0.8g, Fructus Foeniculi 1g, Rhizoma Imperatae 2.5g, Rhizoma Polygonati 0.8g by following crude drug.
The described Chinese medicine composition of the various embodiments described above can be got in proportion during preparation and grind to form the end after each crude drug mixes, and crosses 80～100 mesh sieves and makes powder.During use, the powder after grinding directly can be taken, 4 times on the one, a 2.25g, warm water takes.
The case test
Carcinoma of gastric cardia patient clinical observation after 150 examples are made a definite diagnosis uses Chinese medicine composition of the present invention to cure (sign and symptom are improved fully, swallow normal, happy, in high spirits) 102 examples; Produce effects (sign and symptom are significantly improved, and swallow normal substantially, happy, spiritual fine) 26 examples; Effectively (sign and symptom make moderate progress, and swallow improvement, random thoughts discomfort is arranged slightly, but can accept) 10 examples; Invalid (sign does not have change, and symptom does not have improvement) 12 examples; Effective percentage reaches more than 92%.
Below further set forth the beneficial effect of external medicine composition of the present invention by model case.
Case 1:
Luoning County Korea Spro, the man 50 years old, increased the weight of 20 days because of dysphagia 9 months in 2006.Be diagnosed as carcinoma of gastric cardia October through radiography, endoscopy.And the excision of performing an operation, course of treatment of postoperative chemotherapy, can the influent stream food after leaving hospital, but health obviously descends.In June, 2007, the state of an illness increased the weight of, can not take food, and dysphagia, loss of appetite can only be drunk water or rare rice water, chokes with sobs after the influent stream of the being everlasting food, also with postural dizziness.Go to a doctor in local hospital, esophagoscopy and pathological replacement are diagnosed as the postoperative cardiac carcinoma recurrence.Because patient's body constitution is too poor, can't carry out chemotherapeutic treatment.Examine and see: patient's nutrition is poor, and spirit is poor, becomes thin, and is weak, and the feed difficulty is interrupted the mucoid secretions of vomiting white.
Took the embodiment of the invention 1 Chinese medicine composition only 20 days, symptom makes moderate progress.Continue to take one and a half months, patient's spirit is clearly better, and can advance the semi-fluid food, and muscle power has also obtained recovery, and the check recurrent focus obviously dwindles.Continue and obeyed Chinese medicine composition of the present invention three months, stable disease, the soft diet of can suitably taking food does not have phenomenons such as vomiting, and the mental status further takes a turn for the better, and the check recurrent focus continues to reduce.Take medicine of the present invention after nine months, all diseases are removed entirely, and oneself disappears the check recurrent focus, and weight in patients increases, and in high spirits, diet is normal.Follow up a case by regular visits to so far, not recurrence.
Case 2:
The Yiyang County Wang, the woman, 58 years old, occurred dysphagia companion before half a year and stop that sense is surplus March, it is weak to become thin, shallow complexion is the anemia looks, lassitude, deficiency of QI with disinclination to talk, upper abdomen has a dull ache, press more so, constipation is diagnosed as carcinoma of gastric cardia through hospital.Stop that with swallowing behind the embodiment of the invention 4 medicine first quarter moons sense promptly alleviates, free movement of the bowels is again in conjunction with taking good care of the recovery from illness in four months of QI and blood Drug therapy.
Case 3:
Shengchi County's seat, the man 65 years old, showed through hospital's upper digestive tract radiography because of difficult six months of carrying out property feed in 2008: preventricular stenosis, filling defect, the mucosa wall destroys and interrupts.Gastroscope shows: the hyperemia of pars cardiaca mucosa, and edema has the big aphtha kitchen range of an about 0.5cm * 1cm, pathological replacement: adenocarcinoma, examine and be carcinoma of gastric cardia.Examine and see: patient's epigastrium pain, vomiting clear water sputum, light night in daytime is heavy, influence feed and sleep, weak breath is weak, and health is become thin.Pale tongue, lingual surface water is wet, and tongue is white, soft and thready pulse.
Took the embodiment of the invention 2 Chinese medicine compositions 25, the epigastrium pain relief, vomiting gradually ends, and it is good slightly to sleep, continue to take after two months, gastroscope shows: focus is more preceding significantly dwindles, and symptom is further alleviated, and diet increases, sleep takes a turn for the better, and muscle power is recovered to some extent, and patient's confidence heightens, and spirit takes a turn for the better.After continuing to take 4 months, symptom fades away, and weight increase after 6 months, is checked all normally, and all diseases are all removed, and resume work, and follow up a case by regular visits to so far, and are all right.
Case 4:
Zhang, the man, 46 years old, in October, 2005 because of become thin, dysphagia, through examination in hospital, be diagnosed as carcinoma of gastric cardia, carry out resection operation immediately in hospital, postoperative carries out chemotherapy.In December, 2006 occurs dysphagia once more, tells mucus, symptom such as anemia, and weight loss is the postoperative cardiac carcinoma recurrence through hospital diagnosis, and the row radiotherapy is because of weak can not bearing stops.The patient body weakness adds the radiotherapy reaction, can not have a meal in more than 20 day, only depends on transfusion to earn a bare living.
Took the embodiment of the invention 1 Chinese medicine composition 15, all diseases alleviate, and can advance a small amount of liquid food, and spirit takes a turn for the better.Continue and obeyed 1 month, dysphagia further alleviates, and mucus reduces, and diet is more preceding to increase the small amount of solid of can taking food food to some extent.Continue and obeyed Chinese medicine composition of the present invention 3 months, patient's feed is more smooth, no mucus, and anemia is significantly improved.Take medicine of the present invention after 10 months, symptom almost disappears, and the patient lives normally so far.
Case 5:
What certain, the woman, 68 years old, patient's cause in March breast stomach upset, tired unable, loss of appetite, extremely anemia is in hospital, through B ultrasonic, CT and gastrointestinal image, gastroscope and get the biopsy pathology chemical examination, be diagnosed as: cardiac malignant tumor at the bottom of the stomach belongs to poorly differentiated adenocarcinoma.Patient age is higher, and treatment does not undergo surgery.Beginning before the first quarter moon, the feed difficulty appears in the patient, and having a meal drinks water swallows serious pain, can't swallow, and health is become thin rapidly.
Took the embodiment of the invention 3 Chinese medicine compositions 10, remission can be advanced a little liquid foods smoothly.Continue and obeyed Chinese medicine composition of the present invention 1 month, can independently take food, swallow smoothly.The clothes Chinese medicine composition of the present invention 2 months that continues can also be not limited to rare plastic flow food normally by the three meals in a day feed, normal diet can, have rosy cheeks, the mental status is clearly better.Took Chinese medicine composition of the present invention 8 months, symptom disappears substantially, follows up a case by regular visits to so far 3 years, and the patient is still alive, and the daily life diet is normal.
Case 6:
The Wang, the man 42 years old, occurs food feed dysphagia before the bimester of the patient, symptoms such as that pain, idol have is nauseating, vomiting, pantothenic acid.Hospital gastroscope shows: distal esophagus is cauliflower-like to the irregular protuberance of body of stomach antetheca mucosa, and the surface is congested, mucosal erosion, and pathology shows: a small amount of suspicious adenocarcinoma cell is arranged in the stomach cardia mucosa.The upper digestive tract radiography shows: carcinoma of gastric cardia.
Took the embodiment of the invention 1 Chinese medicine composition 15, each symptom alleviates to some extent.The clothes Chinese medicine composition of the present invention 1 month that continues, dysphagia obviously alleviates, and pain disappears substantially, no longer includes nauseating, vomiting, pantothenic acid symptom.Continue and obey two first quarter moons of Chinese medicine composition of the present invention, patient's feed is relatively more smooth, and pain is ended, and reexamine focus obviously reduces.It is surplus July to take Chinese medicine composition of the present invention, and patient's disease all disappears, and dietetic life is near normal, follows up a case by regular visits to so far that 5 years patients are alive, recurrence.
Claims (4)
1. Chinese medicine composition for the treatment of carcinoma of gastric cardia, it is characterized in that, make 2～4 parts of: Herba Polygoni Avicularis, 0.8～1.5 part of Herba Plantaginis, 0.8～1.2 part of moxa roll, 0.8～1.2 part of Fructus Foeniculi, 1.5～2.5 parts of Rhizoma Imperataes, 0.8～1.2 part of Rhizoma Polygonati by following weight portion crude drug.
2. treat the Chinese medicine composition of carcinoma of gastric cardia according to claim 1, it is characterized in that, make 3 parts of: Herba Polygoni Avicularis, 1 part of Herba Plantaginis, 1 part of moxa roll, 1 part of Fructus Foeniculi, 2 parts of Rhizoma Imperataes, 1 part of Rhizoma Polygonati by following weight portion crude drug.
3. treat the Chinese medicine composition of carcinoma of gastric cardia as claimed in claim 1 or 2, it is characterized in that, can be prepared into any one oral formulations commonly used according to the Chinese drugs agentia method of routine.
4. as the Chinese medicine composition of treatment carcinoma of gastric cardia as described in the claim 3, it is characterized in that described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1187071C (en) * | 2002-12-17 | 2005-02-02 | 李天德 | Liver cancer treating medicine and its prepn |
| CN101279071B (en) * | 2008-05-19 | 2010-07-28 | 王金贵 | Chinese medicinal composition for curing esophagus cancer or cardiac cancer |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1187071C (en) * | 2002-12-17 | 2005-02-02 | 李天德 | Liver cancer treating medicine and its prepn |
| CN101279071B (en) * | 2008-05-19 | 2010-07-28 | 王金贵 | Chinese medicinal composition for curing esophagus cancer or cardiac cancer |
Non-Patent Citations (2)
| Title |
|---|
| 《中国中医基础医学杂志》 20070630 郭淑云 李振华论脾胃气虚导致慢性胃痛的病机与证治 466 1-4 第13卷, 第6期 2 * |
| 《中国肿瘤临床》 19860430 章镜平等 食管_贲门_癌手术治疗456例及其并发症分析 207-209 1-4 第13卷, 第4期 2 * |
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