CN102058842A - Traditional Chinese medicine composition for treating hemiplegic stroke or premonitory apoplexy - Google Patents
Traditional Chinese medicine composition for treating hemiplegic stroke or premonitory apoplexy Download PDFInfo
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- CN102058842A CN102058842A CN2010105739863A CN201010573986A CN102058842A CN 102058842 A CN102058842 A CN 102058842A CN 2010105739863 A CN2010105739863 A CN 2010105739863A CN 201010573986 A CN201010573986 A CN 201010573986A CN 102058842 A CN102058842 A CN 102058842A
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Abstract
The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular to a traditional Chinese medicine composition for treating hemiplegic apoplexy or premonitory apoplexy. The traditional Chinese medicine composition is prepared from the following bulk pharmaceutical chemicals: 100-130g of Astragalus mongholicus, 15-30g of red peony root, 6-12g of hirudo, 10-16g of szechwan lovage rhizome, 10-20g of nutgrass galingale rhizome, 20-30g of suberect spatholobus stem, 15-30g of peach seed, 10-20g of tatarinow sweetflag rhizome,20-30g of wenchow turmeric root tuber,15-30g of Chinese clematis root and rhizome, 15-30g of earthworm, and 10-20g of bile arisaema. The traditional Chinese medicine composition is mainly used for treating hemiplegic apoplexy or premonitory apoplexy, and relieving symptoms of dizziness, hemianesthesia, hemiplegia and aphasis caused by cerebrovascular diseases such as cerebral thrombosis, cerebral infarction, transient cerebral ischemia and arteriosclerotic encephalopathy, and the total effective rate is 96.3%.
Description
Technical field
The invention belongs to the technical field of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of apoplectic hemiplegia or premonitory apoplexy, trade name is referred to as to be stilbene Chinese herbaceous peony capsule for freeing collateral vessels.
Background technology
Apoplectic hemiplegia or premonitory apoplexy are a kind of clinically common ailment of middle-aged and old, frequently-occurring disease, are usually expressed as diseases such as the dizzy desire servant of brain, hemianesthesia, hemiplegia, aphasis.Apoplexy is a cerebrovascular, sickness rate height, disability rate height.Health threat and harm to person in middle and old age increase the weight of, and bring tremendous economic burden and adverse consequences for family and society.At present about how preventing and treating the research topic that apoplexy is countries in the world.The Chinese patent medicine of treatment apoplexy is many, and as quieting drip pill, apoplexy echo ball, NAOXINTONG JIAONANG etc., these medicines all have certain therapeutic effect to apoplexy, but all exist uncertain therapeutic efficacy with degree, can not wait defective at all.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of apoplectic hemiplegia or premonitory apoplexy.
The present invention adopts following technical scheme to realize:
A kind of Chinese medicine composition for the treatment of apoplectic hemiplegia or premonitory apoplexy is characterized in that adopting following bulk drugs to make: 100～130 parts of the Radixs Astragali, 15～30 parts of Radix Paeoniae Rubra, 6～12 parts of Hirudos, 10～16 parts of Rhizoma Chuanxiongs, 10～20 parts of Rhizoma Cyperis, 20～30 parts of Caulis Spatholobis, 15～30 parts in Semen Persicae, 10～20 parts of Rhizoma Acori Graminei, 20～30 parts of Radix Curcumaes, 15～30 parts of Radix Clematidis, 15～30 parts of Pheretimas, 10～20 parts of Arisaema Cum Bile.
The Chinese medicine composition of described treatment apoplectic hemiplegia or premonitory apoplexy is characterized in that adopting following bulk drugs to make: 100 parts of the Radixs Astragali, 15 parts of Radix Paeoniae Rubra, 6 parts of Hirudos, 10 parts of Rhizoma Chuanxiongs, 10 parts of Rhizoma Cyperis, 20 parts of Caulis Spatholobis, 15 parts in Semen Persicae, 10 parts of Rhizoma Acori Graminei, 20 parts of Radix Curcumaes, 15 parts of Radix Clematidis, 15 parts of Pheretimas, 10 parts of Arisaema Cum Bile.
Chinese medicine composition of the present invention can adopt existing known technology to make common various form of Chinese drug, and each crude drug is all buied from regular pharmacy.The Radix Astragali wherein, property is sweet, and tepor is returned lung, spleen, liver, kidney channel, and benefiting QI for strengthening the superficies, arresting sweating take off admittedly.Radix Paeoniae Rubra, bitter in the mouth is slightly cold, and returns Liver Channel, clearing away heat and cooling blood, eliminating stasis to stop pain.Hirudo, salty in the mouth hardship, property are put down, and be poisonous, returns liver, urinary bladder channel, belongs to the in love product of flesh and blood, is used for diseases such as pulmonary heart disease, coronary heart disease, cerebral hemorrhage, hyperlipidemia.Rhizoma Chuanxiong, suffering, temperature is returned liver, gallbladder, pericardium channel, blood-activating and qi-promoting, wind-expelling pain-stopping.Rhizoma Cyperi, hot little hardship is sweet, and is flat, goes into liver, tri-jiao channel, the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.Caulis Spatholobi, bitter, sweet, temperature.Return liver, kidney channel, enrich blood, invigorate blood circulation, collateral dredging.Semen Persicae, bitter, sweet, flat, GUIXIN, liver, large intestine channel, blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Rhizoma Acori Graminei, suffering, hardship, temperature.GUIXIN, stomach warp, removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Radix Curcumae, hot, bitter, cold, return liver, the heart, lung meridian, regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Radix Clematidis, hot salty, temperature, poisonous, go into urinary bladder channel, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the hypochondriac lump of loosing.Pheretima, salty-cold, heat clearing away, spasmolytic, diuresis, detoxifcation.Arisaema Cum Bile, bitter, little suffering, cold.Return lung, liver, spleen channel, removing heat-phlegm, dispelling wind and relieving convulsion.Each crude drug complements each other, and reaches strengthening the body resistance, the effect of blood circulation promoting and blood stasis dispelling collateral dredging, and apoplectic hemiplegia, premonitory apoplexy are cerebrovascular disease.As the dizzy desire servant of brain due to cerebral thrombosis, cerebral infarction, transient cerebral ischemia, the arterial side cardio-encephalopathy, hemianesthesia, hemiplegia, all cards of aphasis.
Chinese medicine composition clinical trial statistics of the present invention is as follows:
1, case and method
2008～2010 years, connect and control patient's 80 examples, male's 56 examples, women's 24 examples, 45 years old mean age.All case is that the cerebrovascular disease clinical manifestation is that diagnostic criteria is determined by apoplectic hemiplegia, premonitory apoplexy all.Give the various pharmaceutical formulations of Chinese medicine composition of the present invention during treatment targetedly, as capsule, powder, decoction etc.Generally, decoction, every day, potion divided secondary to take; Powder, each one the bag, every day secondary; Capsule, each three, every day secondary.
2, efficacy determination
Be as the criterion according to clinical symptom disappearance, be divided into radical cure rehabilitation, produce effects, effective, invalid.
The radical cure rehabilitation: lamprophonia, freedom of movement, life are autonomous, can do labor in general.
Produce effects: language is clear substantially, and action can be lived on one's own life substantially freely substantially.
Effectively: language is clear substantially, but action has inconvenience slightly.
Invalid: brain swoon desire servant, hemianesthesia, hemiplegia, aphasis.
3, curative effect is summed up
| The example number | The radical cure rehabilitation | Produce effects | Effectively | Invalid | Effective percentage |
| 80? | 38? | 24? | 15? | 3? | 96.3％? |
4, model case
Clinical case 1
Yang Pugong, the man, 70 years old, it was surplus to suffer from high disorders of blood+year, recently because motion is violent.And the dizzy desire of prominent sense brain is fallen forward, left limb numbness, walking shakiness, slurred speech, cardiopalmus be weak, the time have stream absurd fantastic, the body of the tongue dimness, tongue subtracts in vain slightly.Head CT is reported as: right side Basal ganglia corona radiata multiple infarctions.Arteries and veins is demonstrate,proved comprehensive: card belongs to apoplexy apoplex involving the channels and collaterals, deficiency of vital energy blood addiction type, controls with benefiting QI for activating blood circulation, the collateral dredging of having one's ideas straightened out. and give Chinese medicine decoction potion 5 doses of every days of the present invention, fry in shallow oil secondary for every dose, sooner or later respectively once.Two examine the smooth and proper improvement of all cards, imitate more not just, continue with 10 doses of decoctions of the present invention, according to preceding canonical usefulness, and are aided with acupuncture and tuina-massage, reconditioning.Three examine that brain is dizzy to be done, and life is taken care of oneself substantially, and all proofs show and take a turn for the better, but have during language unclearly, train so add language rehabilitation.And give the every bag of side's powder of the present invention 6g again, and each one wraps, and one day twice, logotype 15 staggering amounts.Following up a case by regular visits to life can take care of oneself, and advises it to adhere to functional exercise, and the control basis is sick, avoids recurrence.
Clinical case 2
Huo Longfeng, the woman, 57 years old, it was surplus to suffer from hypertension 2 years, tired recently and cause that dizziness, right side numb limbs and tense tendons, walking are weak, lassitude, pale tongue, bitter thin white.Head CT is reported as: left side Basal ganglia and thalamus obstructive disease belong to premonitory apoplexy appoplexy involving the collateral, deficiency of vital energy stagnation of phlegm, the deficiency in origin and excess in superficiality card.The method of treatment collateral dredging that should QI invigorating reduces phlegm, has one's ideas straightened out.Give 5 doses of Chinese medicine soup of the present invention, every day, potion divided the secondary decoction, sooner or later respectively once.Two examine all cards disappears, walks freely, and life can be taken care of oneself, and for consolidating curative effect, gives powder 20 feed rations of the present invention, each bag, and one day two drink, and advise and adhere to treating the basis disease, to strike a proper balance between work and rest, appropriate exercise is taken exercise, and follows up a case by regular visits to healthy as usual.
Clinical case 3
Liang Jiesheng, the man, 62 years old, patient's hypertension 3 years, because of being subjected to YIN-cold to cause dizzy desire servant, left limb numbness, left lower extremity is soft and unable recently, and walking is walked haltingly, body of the tongue dimness, white and thin fur, stringy and slow pulse.Head CT is reported as: right side thalamus infraction, card belong to the apoplexy apoplex involving the channels and collaterals, gas is considered blood nationality, cold coagulation venation.Control with fill temperature warp, promoting blood circulation to remove obstruction in the collateral.Give this Chinese medicine decoction, five feed rations, potion on the one divides the secondary decoction.Two examine all proofs shows improvement, but left lower extremity is still movable unable.So obey 10 doses of Chinese medicine decoction of the present invention again, cooperate acupuncture therapy, limbs training.Three examine that the patient can take care of oneself, smooth running, so give Chinese powder medicine of the present invention 15 days again, every bag 6 grams, one time one bag, a twice-daily, oral.And advise it to adhere to that again reconditioning, control basis are sick, it is as usual to follow up a case by regular visits to recovery from illness thereafter.
Clinical case 4
Fall through prosperous, the man, 69 years old, suffer from the hypotension history, blood pressure is at 110～90/65～50mmhg.Recently tired, playing prominent sense dizziness and blurred vision morning, nose heave foot is light, as stepping on the Cotton Gossypii sense, whole body lassitude, drowsiness desire crouch, speech is unfavorable, complexion greyish white simple and unadorned, pale tongue is dim, white and thin fur, deep,thready and forceless pulse.Head CT is reported as: binswanger disease, slight brain atrophy.The card genus apoplexy appoplexy involving the collateral deficiency of vital energy is not transported, numbness hinders venation, control suitable strongly invigorating primordial QI, promoting blood circulation to remove obstruction in the collateral.Give side's Chinese medicine decoction 5 feed rations of the present invention, 5 doses, every day potion, every dose of decoction twice divides sooner or later each clothes at a draft.Two examine all proofs of patient show to take a turn for the better, but still the time have dizzy sleepy. give 5 doses of Chinese medicine decoction of the present invention again, use as preceding canonical. three to examine the self-induction brains limpid, and stride is as usual.Give side's powder 20 feed rations of the present invention again, every bag 6 grams, each bag, every day, secondary was oral with solid curative effect.
Clinical case 5
Ma Yunxiang, the woman, 49 years old, it was surplus to suffer from sick 2 years of high Xue Shi, and work and exaggerate nearly January, and prominent sense brain is dizzy to turn over servants, walk shakiness, right side numb limbs and tense tendons, sweating while acting, fatigue and weakness, pale tongue, white and thin fur, stringy and thready pulse.Head CT is reported as: left side corona radiata cerebral infarction.Card belongs to the apoplexy appoplexy involving the collateral, and blood stasis due to qi deficiency, channels are subjected to resistance type.Control and should give 5 doses of Chinese medicine decoction of the present invention by the benefiting QI for activating blood circulation collateral dredging, 5 staggering amounts, potion on the one is fried in shallow oil 2 drinks for every dose, sooner or later services once, and is decocted in water for oral dose.Two examine the smooth and proper improvement of all cards, but still sense right side limbs are slightly numb, thus give 5 doses of Chinese medicine decoction of the present invention again, as preceding taking.Three examine that the patient is dizzy to be done, and as usual, the spirit of walk is shaken slightly, gives Chinese medicinal capsule agent 20 feed rations of the present invention again for consolidating curative effect, and every 0.3 restrains, and obeys 3 at every turn, every day secondary.Follow up a case by regular visits to after January: all cards recover as usual, advise it to take regular exercise, actively prevent and treat the basis disease, prevent overweighting controlling.
In addition, Chinese medicine composition of the present invention has no side effect, and through acute toxicity test and long term toxicity test, gives mouse stomach by the dose of clinical permission, and mice is movable normal; Cmax by clinical permission is given the rat administration, and activities in rats and every testing result are no abnormal.
The specific embodiment
Embodiment 1: Radix Astragali 100g, Radix Paeoniae Rubra 15g, Hirudo 6g, Rhizoma Chuanxiong 10g, Rhizoma Cyperi 10g, Caulis Spatholobi 20g, Semen Persicae 15g, Rhizoma Acori Graminei 10g, Radix Curcumae 20g, Radix Clematidis 15g, Pheretima 15g, Arisaema Cum Bile 10g, pulverized 120 purpose smalls after the oven dry, be called every bag 6 grams with Libra.Make powder.
Embodiment 2: Radix Astragali 120g, Radix Paeoniae Rubra 30g, Hirudo 10g, Rhizoma Chuanxiong 16g, Rhizoma Cyperi 15g, Caulis Spatholobi 25g, Semen Persicae 20g, Rhizoma Acori Graminei 15g, Radix Curcumae 30g, Radix Clematidis 25g, Pheretima 20g, Arisaema Cum Bile 15g pulverized 100 mesh sieves and became fine powder after the oven dry, the Capsules of packing into, every 0.3g.
Embodiment 3: Radix Astragali 130g, Radix Paeoniae Rubra 20g, Hirudo 12g, Rhizoma Chuanxiong 12g, Rhizoma Cyperi 20g, Caulis Spatholobi 30g, Semen Persicae 30g, Rhizoma Acori Graminei 20g, Radix Curcumae 25g, Radix Clematidis 30g, Pheretima 30g, Arisaema Cum Bile 20g is combined as potion, adds 800 milliliters in water, slow fire heating 25 minutes, every dose of medicine is fried in shallow oil twice every drink extracting juice and is made decoction for 200 milliliters.
Claims (2)
1. a Chinese medicine composition for the treatment of apoplectic hemiplegia or premonitory apoplexy is characterized in that adopting following bulk drugs to make: 100～130 parts of the Radixs Astragali, 15～30 parts of Radix Paeoniae Rubra, 6～12 parts of Hirudos, 10～16 parts of Rhizoma Chuanxiongs, 10～20 parts of Rhizoma Cyperis, 20～30 parts of Caulis Spatholobis, 15～30 parts in Semen Persicae, 10～20 parts of Rhizoma Acori Graminei, 20～30 parts of Radix Curcumaes, 15～30 parts of Radix Clematidis, 15～30 parts of Pheretimas, 10～20 parts of Arisaema Cum Bile.
2. according to the treatment apoplectic hemiplegia of claim 1 or the Chinese medicine composition of premonitory apoplexy, it is characterized in that adopting following bulk drugs to make: 100 parts of the Radixs Astragali, 15 parts of Radix Paeoniae Rubra, 6 parts of Hirudos, 10 parts of Rhizoma Chuanxiongs, 10 parts of Rhizoma Cyperis, 20 parts of Caulis Spatholobis, 15 parts in Semen Persicae, 10 parts of Rhizoma Acori Graminei, 20 parts of Radix Curcumaes, 15 parts of Radix Clematidis, 15 parts of Pheretimas, 10 parts of Arisaema Cum Bile.
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| CN2010105739863A CN102058842B (en) | 2010-12-01 | 2010-12-01 | Traditional Chinese medicine composition for treating hemiplegic stroke or premonitory apoplexy |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394029A (en) * | 2013-07-22 | 2013-11-20 | 王善海 | Traditional Chinese medicine for treating severe insomnia after cerebral apoplexy |
| CN105770032A (en) * | 2016-03-29 | 2016-07-20 | 首都医科大学附属北京友谊医院 | Novel purpose of traditional Chinese medicine composition |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (en) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
| CN101721664A (en) * | 2008-11-04 | 2010-06-09 | 王生 | Traditional Chinese medicine for treating apoplectic hemiplegia and general paralysis |
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- 2010-12-01 CN CN2010105739863A patent/CN102058842B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (en) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
| CN101721664A (en) * | 2008-11-04 | 2010-06-09 | 王生 | Traditional Chinese medicine for treating apoplectic hemiplegia and general paralysis |
Non-Patent Citations (1)
| Title |
|---|
| 《中医药学报》 20001220 张晋等 名老中医治疗中风经验评述 , 第06期 2 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394029A (en) * | 2013-07-22 | 2013-11-20 | 王善海 | Traditional Chinese medicine for treating severe insomnia after cerebral apoplexy |
| CN103394029B (en) * | 2013-07-22 | 2016-01-27 | 王善海 | A kind of Chinese medicine for the treatment of severe insomnia after cerebral apoplexy |
| CN105770032A (en) * | 2016-03-29 | 2016-07-20 | 首都医科大学附属北京友谊医院 | Novel purpose of traditional Chinese medicine composition |
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| CN102058842B (en) | 2012-01-25 |
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