CN102058728B - Medicament with raw materials containing red tea and truffle - Google Patents
Medicament with raw materials containing red tea and truffle Download PDFInfo
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- CN102058728B CN102058728B CN201010545477.XA CN201010545477A CN102058728B CN 102058728 B CN102058728 B CN 102058728B CN 201010545477 A CN201010545477 A CN 201010545477A CN 102058728 B CN102058728 B CN 102058728B
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- black tea
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Abstract
The invention discloses a medicament with raw materials containing red tea and truffle, belonging to the field of medicines or health card foods. The medicament is characterized by comprising the raw materials of 1-20 parts by weight of red tea, 5-50 parts by weight of truffle and 1-30 parts by weight of one or more of mistletoe, medlar, chrysanthemum, honeysuckle flower, honey, sweet-scented osmanthus, American ginseng, the stem of noble dendrobium and dwarf lilyturf root. Experiment researches prove that the medicament has pharmacological actions of better reducing blood fat, improving the immunity, and the like.
Description
Technical field
The present invention relates to medicine or field of health care food, be specifically related to the medicine that a kind of raw material contains black tea and Truffe.
Background technology
During black tea initiative, be called " black tea ".English is Black tea.There is the chemical reaction centered by tea polyphenols enzymatic oxidation in black tea, the chemical composition change in fresh leaf is larger in the course of processing, and tea polyphenols reduces more than 90%, has produced the new components such as theaflavin, thearubigins.Aroma substance obviously increases than fresh leaf.So black tea has the feature of black tea, red soup, red autumnal leaves and fragrant and sweet taste alcohol.China's black tea kind is the most famous with keemun black tea, is the second largest teas of China, and export volume accounts for 50% left and right of China's Folium Camelliae sinensis total output, and client spreads all over more than 60 countries and regions.What wherein sales volume was maximum is Egypt, the Sudan, Lebanon, Syria, Iraq, Pakistan, Britain and Ireland, Canada, Chile, Germany, Holland and East Bloc.
But some problems and the single defect of the mouthfeel of black tea own along with the black tea manufacture aspect coming out in recent years, make black tea industry meet with unprecedented development bottleneck.Again emergence and the sustainable development of black tea industry, must depend on new research and innovation.
Summary of the invention
For these reasons, the applicant finds by research, take black tea, Truffe is raw material, one or more that add Herba Visci, Fructus Lycii, Flos Chrysanthemi, Flos Lonicerae, Mel, Flos Osmanthi Fragrantis, Radix Panacis Quinquefolii, Herba Dendrobii, Radix Ophiopogonis are prepared into new product, the mouthfeel not only with giving off a strong fragrance, and show through pharmacological experiment study, novel product of the present invention has better pharmacological action.
The present invention is achieved through the following technical solutions.
The medicine that raw material contains black tea and Truffe, is characterized in that raw material comprises black tea 1-20 weight portion, Truffe 5-50 weight portion, one or more 1-30 weight portions of Herba Visci, Fructus Lycii, Flos Chrysanthemi, Flos Lonicerae, Mel, Flos Osmanthi Fragrantis, Radix Panacis Quinquefolii, Herba Dendrobii, Radix Ophiopogonis.
Wherein said black tea 1-10 weight portion, Truffe 10-40 weight portion, one or more 1-20 weight portions of Herba Visci, Fructus Lycii, Flos Chrysanthemi, Flos Lonicerae, Mel, Flos Osmanthi Fragrantis, Radix Panacis Quinquefolii, Herba Dendrobii, Radix Ophiopogonis.
Beverage prepared by its Raw.
Beverage prepared by its Raw.
Pharmaceutical preparation prepared by its Raw or food.
Wherein pharmaceutical preparation is powder, granule, pill or unguentum.
Wherein food is powder, granule, pill or unguentum.
Truffe of the present invention comprises Truffe or Truffe mycelium powder.Truffe can be any edible Truffe or truffles.Truffe mycelium can be natural Truffe sporophore, or artificial culture Truffe sporophore, or the Truffe mycelium powder of fermentation culture, also can use its extract.
Black tea of the present invention includes but not limited to large leaf black tea (ripe tea) or black tea extract or instant black tea or black tea cream.
Pharmacological testing
Test 1
Blood fat reducing test
Test 1 group: commercially available black tea.
Test 2 groups: medicine of the present invention, its Raw is black tea 1g, Truffe 5g, Herba Visci 2g, Herba Dendrobii 2g.
Test 3 groups: medicine of the present invention, its Raw black tea 20g, Truffe 50g, Herba Visci 1g.
Test 4 groups: medicine of the present invention, its Raw black tea 10g, Truffe 30g, Radix Panacis Quinquefolii 6g, Herba Dendrobii 10g, Radix Ophiopogonis 14g.
The brewing method of black tea tea: before experiment,, by tea sample 6.0g, the normal saline that 200ml boils brews, the tinfoil standing 5min that obturages, horse back filtered through gauze, and use filter membrane degerming, obtain the liquid that concentration is 0.03g black tea/ml.
Test 4 groups of preparation methoies of 2 groups-test: extracting in water, extracting liquid filtering, is condensed into the liquid of 0.03g raw material/ml.
Experimental technique: SD rat, is divided at random by body weight: model group, Experimental agents group.Each organized gavage 1.0ml/100g lipomul, and prescription is 30% Adeps Sus domestica, 10% cholesterol, 2% cholate, 0.2% propylthiouracil, 20% Tween 80,20% propylene glycol, 10% sucrose, with distilled water melt into 100ml, continuous 10 days.12 hours socket of the eye venous plexuses of fasting are got blood, detect serum TC, TG, HDL-C and LDL-C content, and again divide into groups by serum TC level.Adjust after grouping, each is organized rat every morning and gives lipomul by above-mentioned modeling test method, emulsion formulations becomes: 20% Adeps Sus domestica, 5% cholesterol, 2% cholate, 0.2% propylthiouracil, 10% tween, 10% propylene glycol, distilled water melt into 100ml for 5% sucrose, point-2 were pressed and were respectively organized dosage 0.1ml/g afternoon 1, gastric infusion, successive administration 16 weeks.After administration finishes for 16 weeks, fasting 12 hours, femoral artery is got blood, and 1% anticoagulant heparin for a part of blood (about 4ml), detects for hemorheology.Another part blood separation serum is for the detection of biochemical indicator.Duration of test claims weekly body weight one time, adjusts dosage, and measure food ration by body weight.Administration detects respectively serum TC, TG level for 16 weeks.
Experimental result is in Table 1:
The impact of table 1 different pharmaceutical on blood fat
Note: with matched group comparison, * P < 0.05, * * P < 0.01; Compare △ P < 0.05 with 1 group of medicine.
Test 2
Improve immunity test
Trial drug:
Test 1 group: commercially available black tea.
Test 2 groups: medicine of the present invention, its Raw is black tea 1g, Truffe 10g, Radix Panacis Quinquefolii 1g.
Test 3 groups: medicine of the present invention, its Raw is black tea 10g, Truffe 40g, structure Qi 3g, Flos Chrysanthemi 4g, Flos Lonicerae 1g, Mel 3g, Radix Panacis Quinquefolii 5g, Herba Dendrobii 2g, Radix Ophiopogonis 2g.
Test 4 groups: black tea 5g, Truffe 25g, Herba Visci 3g, Flos Osmanthi Fragrantis 5g, Radix Ophiopogonis 2g.
The brewing method of black tea tea: before experiment,, by tea sample 6.0g, the normal saline that 200ml boils brews, the tinfoil standing 5min that obturages, horse back filtered through gauze, and use filter membrane degerming, obtain the liquid that concentration is 0.03g black tea/ml.
Test 4 groups of preparation methoies of 2 groups-test: extracting in water, extracting liquid filtering, is condensed into the liquid of 0.03g raw material/ml.
Test method: get mice, random packet, is hypoimmunity in mice modeling in advance, not modeling of normal group, modeling successfully starts administration, and matched group gives normal saline 0.2ml/20g.Administration group gastric infusion dosage 0.06ml/g, successive administration 20 days, 24 hours broken end sacrificed by exsanguination mices after drug withdrawal, under aseptic condition, take out spleen, with RPMI-1640 (containing 10% calf serum), make splenocyte suspension, and mouse boosting cell is adjusted to 5 * 106 cells/m1, be added in 96 well culture plates, every hole 100ul, each spleen adds double (adds ConA, and does not add ConA).ConA 20ul (concentration is 100ug/ml), RPMI-1640 80ul, makes every hole to 200ul volume, in 5%C0237 ℃ of calorstat, cultivates 72 hours, stops cultivating first 24 hours, and every hole adds 3H mono-TdR3.7 * 109 (iucr).With cell harvestor (TITERTEK CELL HARVESTER 550) collecting cell in 49 type glass fiber filter paper, use successively distilled water, 5% 3 ammonia acetic acid, absolute ethanol washing, filter paper is put to 60 ℃ of incubators dries, be added in the cup containing 5ml scintillation solution, through liquid scintillation instrument (BECKMEN LS 9800), survey and participate in radioactivity (cpm), then calculate stimulation index (SI), that is: SI=adds ConA hole cpm/ not add ConA hole cpm.
The impact that table 2 different pharmaceutical transforms hypoimmunity mouse spleen lymphocyte
| Group | Stimulation index |
| Normal group | 0.746±0.078** |
| Matched group | 0.132±0.065 |
| Test 1 group | 0.917±0.123** |
| Test 2 groups | 1.932±0.258**△ |
| Test 3 groups | 2.011±0.219**△ |
| Test 4 groups | 1.989±0.225**△ |
Note: compare * * P < 0.01, * P < 0.05 with matched group; Compare △ P < 0.05 with 1 group of medicine.
Conclusion (of pressure testing): above-mentioned experiment shows, medicine of the present invention has better pharmacological action than commercially available black tea, absolutely proves that the present invention is by after different material compatible combination, significant.
Preparation Example
Embodiment 1
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 1g, Truffe 5g, Mel 1g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 2
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 20g, Truffe 50g, Herba Visci 2g, Flos Chrysanthemi 10g, Herba Dendrobii 7g, Radix Ophiopogonis 11g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 3
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 2g, Truffe 48g, Herba Visci 4g, Fructus Lycii 10g, Herba Dendrobii 2g, Radix Ophiopogonis 9g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 4
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 19g, Truffe 6g, structure Qi 10g, Flos Lonicerae 3g, Flos Osmanthi Fragrantis 9g, Herba Dendrobii 1g, Radix Ophiopogonis 7g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 5
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 10g, Truffe 30g, Flos Chrysanthemi 4g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 6
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 1g part, Truffe 10g, Herba Dendrobii 1g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 7
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 10g, Truffe 40g, Herba Visci 6g, Flos Lonicerae 6g, Radix Panacis Quinquefolii 8g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 8
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 3g, Truffe 13g, Flos Chrysanthemi 7g, Flos Lonicerae 1g, Radix Panacis Quinquefolii 9g, Herba Dendrobii 2g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 9
The medicine that raw material contains black tea and Truffe, raw material comprises black tea 8.5g, Truffe 36g, Herba Visci 2g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Embodiment 10
The medicine that raw material contains black tea and Truffe, raw material black tea 5g, Truffe 22g, Herba Visci 2g, Flos Chrysanthemi 4g, Flos Lonicerae 5g, Mel 2g, Radix Panacis Quinquefolii 1g, Herba Dendrobii 1g, Radix Ophiopogonis 1g.
Beverage prepared by above-mentioned raw materials.
Above-mentioned raw materials is prepared as powder, granule, pill or unguentum.
Claims (5)
1. a medicine for effect for reducing blood fat, is characterized in that medicine material consists of: black tea 1g, Truffe 5g, Herba Visci 2g, Herba Dendrobii 2g; Or raw material consists of black tea 20g, Truffe 50g, Herba Visci 1g.
2. the medicine of a kind of effect for reducing blood fat according to claim 1, is characterized in that beverage prepared by raw material.
3. the medicine of a kind of effect for reducing blood fat according to claim 1, is characterized in that pharmaceutical preparation or food prepared by raw material.
4. the medicine of a kind of effect for reducing blood fat according to claim 3, wherein pharmaceutical preparation is powder, granule, pill or unguentum.
5. the medicine of a kind of effect for reducing blood fat according to claim 3, wherein food is powder, granule, pill or unguentum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010545477.XA CN102058728B (en) | 2010-11-16 | 2010-11-16 | Medicament with raw materials containing red tea and truffle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010545477.XA CN102058728B (en) | 2010-11-16 | 2010-11-16 | Medicament with raw materials containing red tea and truffle |
Publications (2)
| Publication Number | Publication Date |
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| CN102058728A CN102058728A (en) | 2011-05-18 |
| CN102058728B true CN102058728B (en) | 2014-10-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201010545477.XA Expired - Fee Related CN102058728B (en) | 2010-11-16 | 2010-11-16 | Medicament with raw materials containing red tea and truffle |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102640820A (en) * | 2012-04-25 | 2012-08-22 | 楚雄宏桂绿色食品有限公司 | Formula of health tea with truffle and burdock and production method of health tea with truffle and burdock |
| CN102771762A (en) * | 2012-07-20 | 2012-11-14 | 黄晓青 | Truffle health-care product prepared through liquid submerged fermentation and preparation method of truffle health-care product prepared through liquid submerged fermentation |
| CN103931809B (en) * | 2014-01-16 | 2016-07-06 | 贵州涵龙生物科技有限公司 | A kind of Herba Dendrobii black tea |
| CN104432056A (en) * | 2014-12-18 | 2015-03-25 | 杜超峰 | National-wine aroma component and noble dendrobium stem containing composition and preparation method thereof |
| CN104544362A (en) * | 2015-01-29 | 2015-04-29 | 贵州紫荆生物科技有限公司 | Dendrobium sour soup composition and preparation method thereof |
| CN104982571A (en) * | 2015-06-17 | 2015-10-21 | 杜超峰 | Endophyte fermented tea and preparing method thereof |
| CN106509900A (en) * | 2016-11-16 | 2017-03-22 | 马玉娟 | Tuber magnatum health-care product |
| CN110419607A (en) * | 2019-08-28 | 2019-11-08 | 青岛佰福得科技有限公司 | Compound truffle book on Chinese herbal medicine drink and its production method |
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| CN1262106A (en) * | 1999-02-02 | 2000-08-09 | 韩英 | Amercian ginseng tea and preparing process thereof |
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| CN1231856A (en) * | 1999-04-02 | 1999-10-20 | 刘云 | Tea fungus beverage series |
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2010
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|---|---|---|---|---|
| CN1262106A (en) * | 1999-02-02 | 2000-08-09 | 韩英 | Amercian ginseng tea and preparing process thereof |
| CN1332975A (en) * | 2001-07-18 | 2002-01-30 | 邱祥平 | Health care medicinal tea and preparation process thereof |
| CN1231856C (en) * | 2001-11-21 | 2005-12-14 | 佳能株式会社 | Picture taking apparatus and method for operating and processing related file storage |
| CN1739626A (en) * | 2005-09-13 | 2006-03-01 | 孙景茂 | Tea extract dripping pill |
| CN101496593A (en) * | 2008-02-02 | 2009-08-05 | 张云鹏 | Honeysuckle tea beverage |
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