CN102058723A - Traditional Chinese medicine for treating impotence, premature ejaculation and sexual dysfunction and preparation method thereof - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating impotence, premature ejaculation and sexual dysfunction and a preparation method thereof. The invention adopts the following technical scheme: the traditional Chinese medicine is prepared from the following active pharmaceutical ingredients in parts by weight: 20-30 parts of south dodder seed, 10-15 parts of Chinese magnoliavine fruit, 10-15 parts of common cnidium fruit, 10-15 parts of medicinal indianmulberry root, 5-15 parts of oyster and 5-15 parts of barbary wolfberry fruit. The preparation method comprises the following steps: mixing the active pharmaceutical ingredients; then grinding the oyster and the barbary wolfberry fruit into fine powder; decocting the south dodder seed, the Chinese magnoliavine fruit, the common cnidium fruit and the medicinal indianmulberry root in water three times, adding five times amount of water for the first time, decocting for 3 hours, and filtering the decoction; adding three times amount of water to the filter residues for the second time, decocting the filter residues for 2 hours, and filtering the decoction; adding three times amount of water to the filter residues for the third time, decocting the filter residues for 1.5 hours, and filtering the decoction; and merging the three filtrates, concentrating while depressurizing until the relative density is over 1.38, adding fine powder of the oyster and the barbary wolfberry fruit, uniformly mixing, and drying in vacuum. The traditional Chinese medicine has low cost, is convenient to take and has obvious curative effects on impotence, premature ejaculation and sexual dysfunction.

Description

Chinese medicine of treatment sexual impotence, premature ejaculation and sexual dysfunction and preparation method thereof

Technical field

The present invention relates to the field of Chinese medicines, relate to a kind of Chinese medicine for the treatment of sexual impotence, premature ejaculation and sexual dysfunction particularly.

Background technology

Male sexual disorder is a kind of common disease, sickness rate accounts for man's about 10% according to statistics, but be subjected to the constraint of feudal ideology for a long time, many patient's rollings are dared to face, and are ashamed of the property talked, and have influenced individual quality of life and family's conjugal happiness, and the medical worker also often pays little attention to it, its consequence is hardly imaginable, and therefore a lot of people produce inferiority complex, even have the people to get killed for this reason.Such as, sexual impotence and premature ejaculation, two kinds of diseases as the man suffers untold misery are tormenting numerous male, cause a lot of male to fear sexual life, thus cold and detached conjugal relation has influenced the harmony of whole family.But fortunately, along with scientific technological advance and universal, people have had correct understanding gradually to male sexual disorder: on the one hand, male oneself recognizes if sexual dysfunction takes place and will in time treat; On the other hand, the rise of hospital of andrology of specialty is for the diagnoses and treatment of male sexual disorder provides new selection.

Yet, the present Chinese patent medicine that in treatment, is adopted, the cost height, and also curative effect is not remarkable.

Summary of the invention

In order to overcome the above problems, it is low to the purpose of this invention is to provide a kind of cost, taking convenience, the Chinese medicine of treatment sexual impotence, premature ejaculation and sexual dysfunction evident in efficacy.

Another object of the present invention provides a kind of preparation method of Chinese medicine for the treatment of sexual impotence, premature ejaculation and sexual dysfunction.

To achieve these goals, the technical solution used in the present invention is: a kind of Chinese medicine for the treatment of sexual impotence, premature ejaculation and sexual dysfunction, make by following raw material medicaments in part by weight proportioning:

20～30 parts of Semen Cuscutae, 10～15 parts of Fructus Schisandrae Chinensis,

10～15 parts of Fructus Cnidiis, 10～15 parts of Radix Morindae Officinaliss,

5～15 parts of Concha Ostreaes, 5～15 parts of Fructus Lycii.

The preparation method of Chinese medicine of above-mentioned treatment sexual impotence, premature ejaculation and sexual dysfunction comprises the steps:

1) batching: by above-mentioned proportion ingredient;

2) grind: Concha Ostreae and medlar powder are broken into fine powder;

3) decoct: Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Cnidii and Radix Morindae Officinalis are decocted with water three times, add the quintuple decocting for the first time and boiled 3 hours, filter, for the second time adding the triplication decocting in filtering residue boiled 2 hours, filter, in filtering residue, add the triplication decocting for the third time and boiled 1.5 hours, filter;

4) merge three filtrates, being evaporated to relative density is more than 1.38, adds Concha Ostreae and Fructus Lycii fine powder, mixing, vacuum drying.

For taking convenience, can make capsule formulation, preparation method further comprises: behind the vacuum drying, add pharmaceutic adjuvant, granulate, be filled into capsule.

Concha Ostreae and medlar powder are broken into fine powder, and fine powder can be selected sieve by different meshes according to actual preparation, can be 100 orders～200 orders, also can be 200 orders～300 orders, also can be 300～400 orders.For a person skilled in the art, grind to form the conventional knowledge that fine powder is this area.

Pharmaceutic adjuvant (pharmaceutical excipients) is meant when preparation prescription designs, and adds the general designation of all the medicinal materials except that principal agent in the prescription for mouldability, effectiveness, stability, the safety that solves preparation.Inventive point of the present invention is to filter out Six-element Chinese medicine from numerous raw material of Chinese medicine, and the science compatibility has reached the purpose for the treatment of.The interpolation of excipient substance is to be convenient to granulate, molding, therefore, and can be according to actual preparation, pharmaceutic adjuvant and consumption thereof that screening is suitable, this is conventional knowledge for a person skilled in the art.Pharmaceutic adjuvant commonly used has: starch, dextrin, lactose, gelatin, ethanol, glycerol, chitosan, vaseline, propylene glycol, magnesium stearate or microcrystalline Cellulose or the like.

The pharmacology of the crude drug that the present invention adopts, the property of medicine is as follows:

Semen Cuscutae: [meridian distribution of property and flavor] is sweet, temperature.Return the liver,kidney,spleen warp.[function cures mainly] nourishing the liver and kidney, the controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright antidiarrheal.Be used for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.

Fructus Schisandrae Chinensis: [meridian distribution of property and flavor] acid, sweet, temperature.Return lung, the heart, kidney channel.[function cures mainly] convergence is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Be used for the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.

Fructus Cnidii: [meridian distribution of property and flavor] is hot, bitter, temperature; Slightly poisonous.Return kidney channel.[function cures mainly] warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing.Be used for sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; The external treatment vulval eczema, married woman's pudendal pruritus; Trichomonal vaginitis.

Radix Morindae Officinalis: [meridian distribution of property and flavor] is sweet, suffering, tepor.Return kidney, Liver Channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Be used for impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, the muscles and bones flaccidity is soft.

Concha Ostreae: [meridian distribution of property and flavor] is salty, is slightly cold.Return liver, gallbladder, kidney channel.[function cures mainly] tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.Be used for the palpitation with fear insomnia, vertigo and tinnitus, scrofula sucutaneous nodule ， mass in the abdomen mass in the abdomen.The Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.Be used for spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.

Fructus Lycii: [meridian distribution of property and flavor] is sweet, and be flat.Return liver, kidney channel.[function cures mainly] nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.

The present invention is as follows to sexual impotence, premature ejaculation and sexual dysfunction patient's treatment clinical observation:

(1) physical data:

Sexual impotence: 153 routine medical histories 5～10 years.

Premature ejaculation: 113 routine medical histories 5～10 years.

Sexual dysfunction: 185 examples, medical history 5～10 years.

(2) Therapeutic Method

Get among the embodiment 1 capsule of further making.

Instructions of taking: take twice every day, each 3,20 is a course of treatment.Take two courses of treatment.

(3) therapeutic outcome (seeing Table 1)

Table 1 is the curative effect clinical observation after treating

The invention has the beneficial effects as follows: the present invention is guidance with the theory of Chinese medical science, and the science compatibility with Six-element Chinese medicine synergism, has YIN nourishing and YANG strengthening, the effect of the kidney invigorating.By clinical observation, the impotence patient cure rate is reached 50.3%, total effective rate is 96.1%; Premature ejaculation patient cure rate is reached 53.1%, and total effective rate is 95.6%; Sexual dysfunction patient cure rate is reached 51.9%, and total effective rate is 95.1%.The present invention has tangible curative effect for sexual impotence, premature ejaculation and sexual dysfunction.

The specific embodiment:

Embodiment 1

A kind of Chinese medicine for the treatment of sexual impotence, premature ejaculation and sexual dysfunction, make by following crude drug:

Semen Cuscutae 22.5kg, Fructus Schisandrae Chinensis 13.5kg,

Fructus Cnidii 13.5kg, Radix Morindae Officinalis 13.5kg,

Concha Ostreae 10kg, Fructus Lycii 10kg.

Preparation method is as follows:

1) batching: by above-mentioned proportion ingredient;

2) grind: Concha Ostreae and medlar powder are broken into fine powder;

3) decoct: Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Cnidii, Radix Morindae Officinalis are decocted with water three times, add the quintuple decocting for the first time and boiled 3 hours, filter, for the second time adding the triplication decocting in filtering residue boiled 2 hours, filter, in filtering residue, add the triplication decocting for the third time and boiled 1.5 hours, filter;

4) merge three filtrates, being evaporated to relative density is more than 1.38 (80 ℃), adds Concha Ostreae and Fructus Lycii fine powder, mixing, and vacuum drying is made dry extract.

5) further add pharmaceutic adjuvant in dry extract, granulate, make 20 order granules, be filled into capsule, make capsule, specification is the 0.3g/ grain.

Embodiment 2

A kind of Chinese medicine for the treatment of sexual impotence, premature ejaculation and sexual dysfunction, make by following raw material:

Semen Cuscutae 20.2kg, Fructus Schisandrae Chinensis 13.9kg,

Fructus Cnidii 11.5kg, Radix Morindae Officinalis 11.9kg,

Concha Ostreae 14.3kg, Fructus Lycii 5.5kg.

Preparation method is as follows:

1) batching: by above-mentioned proportion ingredient;

2) grind: Concha Ostreae and medlar powder are broken into fine powder;

3) decoct: Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Cnidii, Radix Morindae Officinalis are decocted with water three times, add the quintuple decocting for the first time and boiled 3 hours, filter, for the second time adding the triplication decocting in filtering residue boiled 2 hours, filter, in filtering residue, add the triplication decocting for the third time and boiled 1.5 hours, filter;

4) merge three filtrates, being evaporated to relative density is more than 1.38, adds Concha Ostreae and Fructus Lycii fine powder, mixing, and vacuum drying makes dry extract.

5) further add pharmaceutic adjuvant in dry extract, granulate, make 20 order granules, be filled into capsule, make capsule, specification is the 0.3g/ grain.

Embodiment 3

A kind of Chinese medicine for the treatment of sexual impotence, premature ejaculation and sexual dysfunction, make by following crude drug:

Semen Cuscutae 28.6kg, Fructus Schisandrae Chinensis 10.3kg,

Fructus Cnidii 14.7kg, Radix Morindae Officinalis 14.1kg,

Concha Ostreae 5.5kg, Fructus Lycii 14.4kg.

Preparation method is as follows:

1) batching: by above-mentioned proportion ingredient;

2) grind: Concha Ostreae and medlar powder are broken into fine powder;

3) decoct: Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Cnidii, Radix Morindae Officinalis are decocted with water three times, add the quintuple decocting for the first time and boiled 3 hours, filter, for the second time adding the triplication decocting in filtering residue boiled 2 hours, filter, in filtering residue, add the triplication decocting for the third time and boiled 1.5 hours, filter;

4) merge three filtrates, being evaporated to relative density is more than 1.38, adds Concha Ostreae and Fructus Lycii fine powder, mixing, vacuum drying.

5) further add pharmaceutic adjuvant in dry extract, granulate, make 20 order granules, be filled into capsule, make capsule, specification is the 0.3g/ grain.

Claims (3)

1. Chinese medicine for the treatment of sexual impotence, premature ejaculation and sexual dysfunction is characterized in that being made by following raw material medicaments in part by weight proportioning:

20～30 parts of Semen Cuscutae, 10～15 parts of Fructus Schisandrae Chinensis,

10～15 parts of Fructus Cnidiis, 10～15 parts of Radix Morindae Officinaliss,

5～15 parts of Concha Ostreaes, 5～15 parts of Fructus Lycii.

2. the preparation method of Chinese medicine of the described treatment sexual impotence of claim 1, premature ejaculation and sexual dysfunction is characterized in that comprising the steps:

1) batching: by the described proportion ingredient of claim 1;

2) grind: Concha Ostreae and medlar powder are broken into fine powder;

3) decoct: Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Cnidii and Radix Morindae Officinalis are decocted with water three times, add the quintuple decocting for the first time and boiled 3 hours, filter, for the second time adding the triplication decocting in filtering residue boiled 2 hours, filter, in filtering residue, add the triplication decocting for the third time and boiled 1.5 hours, filter;

4) merge three filtrates, being evaporated to relative density is more than 1.38, adds Concha Ostreae and Fructus Lycii fine powder, mixing, vacuum drying.

3. according to the preparation method of Chinese medicine of the described treatment sexual impotence of claim 2, premature ejaculation and sexual dysfunction, it is characterized in that: behind the vacuum drying, add pharmaceutic adjuvant, granulate, be filled into capsule.