CN102038978A - Hemodialysis concentrate - Google Patents
Hemodialysis concentrate Download PDFInfo
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- CN102038978A CN102038978A CN200910197440XA CN200910197440A CN102038978A CN 102038978 A CN102038978 A CN 102038978A CN 200910197440X A CN200910197440X A CN 200910197440XA CN 200910197440 A CN200910197440 A CN 200910197440A CN 102038978 A CN102038978 A CN 102038978A
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- hemodialysis
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Abstract
The invention aims at providing a hemodialysis concentrate which is characterized in that the production cost is low, the packing cost is low, the transportation cost is low, the storing cost is low, the components are even and the content accuracy is high. The hemodialysis concentrate comprises an acidic concentrate and a bicarbonate concentrate, wherein the acidic concentrate is composed of solid sodium chloride, liquid potassium chloride, calcium chloride, magnesium chloride and an acidic regulator. In the preparation process of the acidic concentrate, the sodium chloride is prepared as a solid, the potassium chloride, the calcium chloride, the magnesium chloride, the acidic regulator and the like are prepared as liquids. The bicarbonate concentrate (comprising sodium bicarbonate) is prepared by means of a normal method. The hemodialysis concentrate provided by the invention has the advantages that the volume of the finished product is reduced greatly due to that the sodium chloride which has the biggest volume is solid, and the components are even and the accuracy for the concentration of ionic solution is high due to the form of combined solid and liquid.
Description
Technical field
The present invention relates to one of used conventional consumptive material of medical blood dialysis treatment, is a kind of hemodialysis concentrate.
Background technology
The patient of uremia is because renal function depletion, can't excrete the former urotoxin that should discharge by kidney, so that intravital uremic concentration raises, and hemodialysis just with sordid in the health, contain the high blood of uremic and guide, through hemodialyzer, filter some uremics, and then blood that these were dialysed, clean is sent back in the body, through such treatment, intravital uremic reduces, and symptom alleviates naturally.Because uremic patient often merges sodium, potassium, calcium, phosphorus, magnesium and soda acid ... the imbalance that waits, so use the suitably dialysis solution of allotment, the effect via dialysis improves this situation.Because dialysate volumes is bigger, for convenience of transportation, adopt usually each component of dialysis solution is mixed and made into concentrate, after hospital, use preceding redilution to become normal dialysis solution.The preparation of conventional hemodialysis concentrate at present, for preventing the precipitation of calcium carbonate, magnesium carbonate, the hemodialysis concentrate is separated into two kinds of concentrate, acid concentrate (containing sodium chloride, potassium chloride, calcium chloride, magnesium chloride, acid regulator) and bicarbonate concentrate (containing sodium bicarbonate).The wherein preparation of acid concentrate, be divided into two kinds of solid and liquid again: acid concentrate prepares with pure solid, advantage is that production cost is low, packing cost is low, cost of transportation is low, storage cost is low, shortcoming is because the molecular weight and the content difference of potassium chloride, calcium chloride, magnesium chloride, acid regulator, cause when preparing with solid, each component is inhomogeneous, the content accuracy is low; Acid concentrate prepares with neat liquid, and advantage is that each component is even, content accuracy height, and shortcoming is production cost height, packing cost height, cost of transportation height, storage cost height.
Summary of the invention
The objective of the invention is to provide that a kind of production cost is low, packing cost is low, cost of transportation is low, storage cost is low, the hemodialysis concentrate that component evenly, the content accuracy is high.
The present invention is achieved in that a kind of hemodialysis concentrate, comprises acid concentrate and bicarbonate concentrate, it is characterized in that described acid concentrate is made up of potassium chloride, calcium chloride, magnesium chloride, the acid regulator of solid sodium chloride and liquid.
The present invention is in the preparation of (containing sodium chloride, potassium chloride, calcium chloride, magnesium chloride, acid regulator) of acid concentrate, wherein sodium chloride is prepared with solid, with potassium chloride, calcium chloride, magnesium chloride, acid regulator etc. with liquid preparation (because sodium chloride-containing not, can reduce liquid capacity more than 90%, reduce cost significantly).Bicarbonate concentrate (containing sodium bicarbonate) prepares with conventional method.
In preparation process of the present invention, can according to actual needs acid concentrate be divided into the proportioning of 5 person-portions or 10 person-portions or N person-portion.Acid concentrate with 10 person-portions is an example, needed solid sodium chloride is about 10.5kg (a component), the more about 261g of potassium chloride, the about 450g of calcium chloride, the about 178g of magnesium chloride, the about 307g of acid regulator (using glacial acetic acid herein) is dissolved in the dialysis water making 2500ml solution (b component).Before the hemodialysis, a component and b component being mixed and added dialysis water fully dissolves to 50L and evenly obtains A liquid, obtaining bicarbonate solution after bicarbonate concentrate (as sodium bicarbonate) being diluted with dialysis water is B liquid again, according to certain proportion (pressing the dialysis solution standard) above-mentioned A liquid is connected haemodialysis control unit dialysis solution matching system with B liquid and reverse osmosis water (RO water) again, can carries out hemodialysis.
Because the molecular weight and the content difference of potassium chloride, calcium chloride, magnesium chloride, acid regulator, cause when preparing with solid, each component is inhomogeneous, and liquid form of the present invention just can reach and the identical even ion concentration of the acid concentrate of neat liquid.
Following table be the preparation of acid concentrate of 5 person-portions, 10 person-portions, 20 person-portions with its usage:
In sum, the present invention has dwindled finished-product volume greatly owing to the sodium chloride that occupies maximum volume is a solid, and production cost, packing cost, cost of transportation, storage cost reduce significantly.Because the molecular weight and the content difference of potassium chloride, calcium chloride, magnesium chloride, acid regulator, cause when preparing with solid, each component is inhomogeneous, only with liquid form of the present invention, just can reach even completely, potassium chloride in the liquid, calcium chloride, magnesium chloride, acid regulator, it is even both to have kept each component, guarantees the advantage that the solution ion concentration accuracy is high again.
The specific embodiment
Acid concentrate with 10 person-portions is an example, needed solid sodium chloride is about 10.5kg (a component), the more about 261g of potassium chloride, the about 450g of calcium chloride, the about 178g of magnesium chloride, the about 307g of acid regulator (using glacial acetic acid herein) is dissolved in the dialysis water making 2500ml solution (b component).Before the hemodialysis, a component and b component being mixed and added dialysis water fully dissolves to 50L and evenly obtains A liquid, obtaining bicarbonate solution after bicarbonate concentrate (as sodium bicarbonate) being diluted with dialysis water is B liquid again, according to certain proportion (pressing the dialysis solution standard) above-mentioned A liquid is connected haemodialysis control unit dialysis solution matching system with B liquid and reverse osmosis water (RO water) again, can carries out hemodialysis.
Claims (1)
1. a hemodialysis concentrate comprises acid concentrate and bicarbonate concentrate, it is characterized in that described acid concentrate is made up of potassium chloride, calcium chloride, magnesium chloride, the acid regulator of solid sodium chloride and liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910197440XA CN102038978A (en) | 2009-10-20 | 2009-10-20 | Hemodialysis concentrate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910197440XA CN102038978A (en) | 2009-10-20 | 2009-10-20 | Hemodialysis concentrate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102038978A true CN102038978A (en) | 2011-05-04 |
Family
ID=43905733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200910197440XA Pending CN102038978A (en) | 2009-10-20 | 2009-10-20 | Hemodialysis concentrate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102038978A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726566A (en) * | 2016-03-25 | 2016-07-06 | 吉林省富生医疗器械有限公司 | Hemodialysis condensate capable of being used online |
| CN106727678A (en) * | 2016-12-14 | 2017-05-31 | 吉林省富生医疗器械有限公司 | Haemodialysis A concentrates and its special self-supporting packaging bag |
| CN108066356A (en) * | 2018-02-05 | 2018-05-25 | 济泰（上海）生物科技有限公司 | A kind of haemodialysis concentrate |
| CN108420828A (en) * | 2018-03-30 | 2018-08-21 | 吉林省富生医疗器械有限公司 | A kind of haemodialysis concentrate improving residual renal function |
| CN108969533A (en) * | 2018-10-10 | 2018-12-11 | 天津市肾友达医疗设备技术开发有限公司 | A kind of dialysate concentrate |
| CN109069720A (en) * | 2016-03-18 | 2018-12-21 | 海默普拉斯有限责任公司 | The method for being used to prepare the unit of at least one haemodialysis concentrate solution and preparing this solution |
| CN109982684A (en) * | 2016-11-21 | 2019-07-05 | 费森尤斯医疗护理德国有限责任公司 | For manufacturing the method, equipment and the tank that are used for the liquid acidic concentrate of haemodialysis control unit |
| CN113368129A (en) * | 2021-06-28 | 2021-09-10 | 广州骐骥生物科技有限公司 | Sugar-free bicarbonate hemodialysis concentrated solution and preparation method thereof |
| CN113827800A (en) * | 2021-10-26 | 2021-12-24 | 常州华岳微创医疗器械有限公司 | Ultrapure hemodialysis concentrated solution and preparation process thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1448145A (en) * | 2003-04-30 | 2003-10-15 | 广州康盛生物科技有限公司 | Bicarbonate dry powder composition for hemodialysis |
| CN1602210A (en) * | 2002-01-15 | 2005-03-30 | 哈斯医药技术有限公司 | Prodn of dialysis concentrate from highly densified concentrate precursouand device for using on site of dialysis |
-
2009
- 2009-10-20 CN CN200910197440XA patent/CN102038978A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1602210A (en) * | 2002-01-15 | 2005-03-30 | 哈斯医药技术有限公司 | Prodn of dialysis concentrate from highly densified concentrate precursouand device for using on site of dialysis |
| CN1448145A (en) * | 2003-04-30 | 2003-10-15 | 广州康盛生物科技有限公司 | Bicarbonate dry powder composition for hemodialysis |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109069720A (en) * | 2016-03-18 | 2018-12-21 | 海默普拉斯有限责任公司 | The method for being used to prepare the unit of at least one haemodialysis concentrate solution and preparing this solution |
| CN105726566A (en) * | 2016-03-25 | 2016-07-06 | 吉林省富生医疗器械有限公司 | Hemodialysis condensate capable of being used online |
| CN109982684A (en) * | 2016-11-21 | 2019-07-05 | 费森尤斯医疗护理德国有限责任公司 | For manufacturing the method, equipment and the tank that are used for the liquid acidic concentrate of haemodialysis control unit |
| CN109982684B (en) * | 2016-11-21 | 2022-04-08 | 费森尤斯医疗护理德国有限责任公司 | Method, apparatus and tank for producing a liquid acidic concentrate for hemodialysis machines |
| CN106727678A (en) * | 2016-12-14 | 2017-05-31 | 吉林省富生医疗器械有限公司 | Haemodialysis A concentrates and its special self-supporting packaging bag |
| CN108066356A (en) * | 2018-02-05 | 2018-05-25 | 济泰（上海）生物科技有限公司 | A kind of haemodialysis concentrate |
| CN108420828A (en) * | 2018-03-30 | 2018-08-21 | 吉林省富生医疗器械有限公司 | A kind of haemodialysis concentrate improving residual renal function |
| CN108420828B (en) * | 2018-03-30 | 2020-12-29 | 吉林省富生医疗器械有限公司 | Hemodialysis concentrate for improving residual renal function |
| CN108969533A (en) * | 2018-10-10 | 2018-12-11 | 天津市肾友达医疗设备技术开发有限公司 | A kind of dialysate concentrate |
| CN113368129A (en) * | 2021-06-28 | 2021-09-10 | 广州骐骥生物科技有限公司 | Sugar-free bicarbonate hemodialysis concentrated solution and preparation method thereof |
| CN113827800A (en) * | 2021-10-26 | 2021-12-24 | 常州华岳微创医疗器械有限公司 | Ultrapure hemodialysis concentrated solution and preparation process thereof |
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Application publication date: 20110504 |