CN102028102A - Natural and safe growth-type feed additive - Google Patents
Natural and safe growth-type feed additive Download PDFInfo
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- CN102028102A CN102028102A CN2010105777140A CN201010577714A CN102028102A CN 102028102 A CN102028102 A CN 102028102A CN 2010105777140 A CN2010105777140 A CN 2010105777140A CN 201010577714 A CN201010577714 A CN 201010577714A CN 102028102 A CN102028102 A CN 102028102A
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Abstract
The invention relates to a natural and safe growth-type feed additive which contains L-arginine-alpha-oxoglutarate, wherein the L-arginine and alpha-oxoglutarate are salified in the mole ratio of 1:2-5:1 and the weight ratio of the L-arginine-alpha-oxoglutarate added to the feed and the daily ration for animals to the feed and the daily ration for animals is 1:50-200. The weight ratio of the additive to the feed is 1:50-100 for livestock animals, 1:100-200 for poultry animals and 1:50-100 for aquatic animals.
Description
Technical field
The present invention relates to a kind of feed addictive, relate to a kind of animal feed additive of growing of promoting specifically.
Background technology
L-arginine-alpha-ketoglutarate, English name are L-Arginine-alpha-Ketoglutarate, and English is called for short AAKG, are different from the crystalline mixture of L-arginine and KG, and there is not sat linkage between the two in common mixt.L-arginine-alpha-ketoglutarate is white or light yellow crystal, and soluble in water, HCl and NaOH solution are slightly soluble in ethanol, are insoluble to acetone, ether etc.
L-arginine-alpha-ketoglutarate is a kind of amidates health products that sales volume increases day by day on the present international market, as functional nutrient hardening agent and liver-protecting medicine, be mainly used in physique and strengthen tonic, promote the quick growth and the recovery of muscle, promote the absorption of liver cell, safeguard that liver function normally waits effect nutrition and energy.Its major physiological mechanism is that L-arginine-alpha-ketoglutarate can promote nitric oxide production level in a short time, promotes and the expansion muscular movement, and then promotes the quick growth and the recovery of muscle, gains in strength and energy.
L-arginine-alpha-ketoglutarate is in the aqueous solution, and can dissociate forms arginine and KG, thereby also can be used as KG or arginic donor, under certain conditions, uses as the substitute of arginine or KG.Arginine is the important source material of the conditionity essential amino acid that can not lack in the human body and synthetic protein, creatine, is the important mesostate of organism urea cycle, also is nitric oxide production lead.And KG has very strong regulating and controlling effect to the metabolism of protein, and is important substance and the production capacity carrier that promotes tricarboxylic acid cycle.(U.S. Pat P 7645742; USP 6905707; USP 7,645, and 742)
In existing document, do not see that L-arginine-alpha-ketoglutarate is applied in the animal feed additive.
Summary of the invention
The growth form feed addictive that the purpose of this invention is to provide a kind of function admirable, its component is fully natural, as the application of human health care's product, without any side effects to human body, as animal feed additive, can improve amino acid whose balanced degree in the feed, improve the digestive utilization ratio of feed protein, reduce the crude protein in the feed, and significantly promote growth of animal.
The object of the present invention is achieved like this: ingredient is L-arginine-alpha-ketoglutarate in its prescription, wherein L-arginine and KG can 1: 2～5: 1 proportioning salify of mol ratio (preparation method sees Chinese patent 200710063477.4,200710063478.9,200710063479.3, CN 101591271A).Joining the L-arginine-alpha-ketoglutarate amount in the feed and the weight ratio of animal daily ration is 1: 50～200, wherein be used for the livestock animal, the weight ratio of this additive and feed is 1: 50～100, be used for the poultry animal, the weight ratio of this additive and feed is 1: 100～200, be used for the aquatic product animal, the weight ratio of additive and feed is 1: 50～100.
The present invention has following effect:
1, this animal feed additive is to be applied to animal feed behind two kinds of amino acid salifies that have been present in human body, human body is perfectly safe;
2, this animal feed additive can significantly promote the growth of poultry, livestock, obviously improves culture benefit;
3, this animal feed additive can promote aquatic animal to make full use of the protein in the feed, can promote its growth, prevents the generation of diseases such as fatty liver, flower liver; Fish, shell-fish had feeding active;
4, the steady chemical structure of this animal feed is convenient to processing and is stored, and does not have incompatibility, can significantly improve production performance;
The specific embodiment
Below will the invention will be further described by instantiation:
Example one
14 piggys that same sow is given birth to, after the phase of breast-feeding, it is divided into 2 groups, raise respectively for every group each 7, feeds utilized identical, experimental group adds feed addictive with weight ratio at 1: 100 in feed, and additive is that (L-arginine and KG are with 1: 1 salify of mol ratio for L-arginine-alpha-ketoglutarate, also claim single arginine ketoglutarate), control group does not add.Raised full 12 months, and butchered sale simultaneously for two groups, experimental group weight ratio control group is high by 32% as a result.
Example two
Raise 40 of Beijing ducks, feeds utilized identical, wherein experimental group is 20, in the feed with weight ratio 1: 200, L-arginine and KG are with 2: 1 salifies of mol ratio in the additive, not doping of control group is raised identical time and is slaughtered respectively after becoming the commodity duck, and the weight ratio control group of experimental group duck is high by 25%.
Embodiment three
In the fish pond of two raising identical type, a slice is as experimental group, in feed, add feed addictive at 1: 50 with weight ratio, wherein L-arginine and KG are with 3: 1 salifies of mol ratio, another sheet is organized not doping in contrast, raises after 12 months, salvages respectively, respectively get 100 fishes at random and weigh, experimental group is higher by 20% than control group weight.
Embodiment four
60 of the fryer chicks of 10 ages in days are divided into two groups at random, wherein experimental group is 30, add additive at 1: 200 with weight ratio in the feed, L-arginine and KG are with 5: 1 salifies of mol ratio in the additive, not doping of control group, raised when delivering for sale in 35 days and slaughter respectively, the weight ratio control group of experimental group chicken is high by 40%.
Claims (3)
1. natural safe growth form feed addictive, it is characterized in that: L-arginine and KG salify are 1: 2～5: 1 with molar ratio computing.
2. feed addictive according to claim 1 is characterized in that: the addition of additive and animal daily ration, with weight ratio count 1: 50～200.Wherein be used for the livestock animal, the weight ratio of this additive and feed is 1: 50～100, is used for the poultry animal, and the weight ratio of this additive and feed is 1: 100～200, is used for the aquatic product animal, and the weight ratio of additive and feed is 1: 50～100.
3. the application of feed addictive according to claim 1 in preparation promotion growth feed is characterized in that the application in preparation promotion growth feed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105777140A CN102028102A (en) | 2010-12-08 | 2010-12-08 | Natural and safe growth-type feed additive |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105777140A CN102028102A (en) | 2010-12-08 | 2010-12-08 | Natural and safe growth-type feed additive |
Publications (1)
| Publication Number | Publication Date |
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| CN102028102A true CN102028102A (en) | 2011-04-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105777140A Pending CN102028102A (en) | 2010-12-08 | 2010-12-08 | Natural and safe growth-type feed additive |
Country Status (1)
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| CN (1) | CN102028102A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103168972A (en) * | 2013-04-19 | 2013-06-26 | 中国水产科学研究院黑龙江水产研究所 | Feed capable of enhancing growth performance and protein deposition of carp |
| CN104304685A (en) * | 2014-11-14 | 2015-01-28 | 中国水产科学研究院黑龙江水产研究所 | Feed additive for increasing protein utilization rate of sturgeon feed and addition method of feed additive |
| CN104489247A (en) * | 2014-11-29 | 2015-04-08 | 张旭 | Feed for increasing protein of crucian |
| CN105029087A (en) * | 2015-08-26 | 2015-11-11 | 中国科学院亚热带农业生态研究所 | Application of alpha-ketoglutaric acid dipotassium to preparation of pig feed |
| CN111387349A (en) * | 2016-07-07 | 2020-07-10 | 中国农业大学 | Animal feeding additive and animal feeding method |
| CN114868842A (en) * | 2022-05-09 | 2022-08-09 | 黑龙江金象生化有限责任公司 | Coated nutritional feed additive for preventing piglet anemia and promoting immune function, and preparation method and application thereof |
Citations (4)
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| DE19836450A1 (en) * | 1998-08-12 | 2000-02-17 | Sueddeutsche Kalkstickstoff | Stable animal feed formulation containing pyruvic acid, e.g. supplement for horse, dog and cat, also contains aminoacid, other organic acid and/or physiologically valuable additive |
| CN101011372A (en) * | 2007-02-02 | 2007-08-08 | 北京和为康医药科技有限公司 | Preparing method of alpha-ketoglutaric acid-arginine salt and its use for treating hepatic disease |
| CN101124943A (en) * | 2007-09-13 | 2008-02-20 | 武汉工业学院 | Feed additive capable of increasing animal and bird intestines physiological function |
| CN101301285A (en) * | 2003-07-01 | 2008-11-12 | 艾森蒂斯股份公司 | Use of alpha-ketoglutaric acid for the treatment of malnutrition or high plasma glucose condition |
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2010
- 2010-12-08 CN CN2010105777140A patent/CN102028102A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19836450A1 (en) * | 1998-08-12 | 2000-02-17 | Sueddeutsche Kalkstickstoff | Stable animal feed formulation containing pyruvic acid, e.g. supplement for horse, dog and cat, also contains aminoacid, other organic acid and/or physiologically valuable additive |
| CN101301285A (en) * | 2003-07-01 | 2008-11-12 | 艾森蒂斯股份公司 | Use of alpha-ketoglutaric acid for the treatment of malnutrition or high plasma glucose condition |
| CN101011372A (en) * | 2007-02-02 | 2007-08-08 | 北京和为康医药科技有限公司 | Preparing method of alpha-ketoglutaric acid-arginine salt and its use for treating hepatic disease |
| CN101124943A (en) * | 2007-09-13 | 2008-02-20 | 武汉工业学院 | Feed additive capable of increasing animal and bird intestines physiological function |
Non-Patent Citations (1)
| Title |
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| 李爱平等: "精氨酸复盐的合成研究及应用进展", 《江苏化工》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103168972A (en) * | 2013-04-19 | 2013-06-26 | 中国水产科学研究院黑龙江水产研究所 | Feed capable of enhancing growth performance and protein deposition of carp |
| CN104304685A (en) * | 2014-11-14 | 2015-01-28 | 中国水产科学研究院黑龙江水产研究所 | Feed additive for increasing protein utilization rate of sturgeon feed and addition method of feed additive |
| CN104489247A (en) * | 2014-11-29 | 2015-04-08 | 张旭 | Feed for increasing protein of crucian |
| CN105029087A (en) * | 2015-08-26 | 2015-11-11 | 中国科学院亚热带农业生态研究所 | Application of alpha-ketoglutaric acid dipotassium to preparation of pig feed |
| CN111387349A (en) * | 2016-07-07 | 2020-07-10 | 中国农业大学 | Animal feeding additive and animal feeding method |
| CN114868842A (en) * | 2022-05-09 | 2022-08-09 | 黑龙江金象生化有限责任公司 | Coated nutritional feed additive for preventing piglet anemia and promoting immune function, and preparation method and application thereof |
| CN114868842B (en) * | 2022-05-09 | 2023-09-01 | 黑龙江金象生化有限责任公司 | Coated nutritional feed additive for preventing anemia and promoting immune function of piglets and preparation method and application thereof |
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Application publication date: 20110427 |