CN102007943A - Aqueous tick repellent aerosol - Google Patents

Aqueous tick repellent aerosol Download PDF

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Publication number
CN102007943A
CN102007943A CN201010532857XA CN201010532857A CN102007943A CN 102007943 A CN102007943 A CN 102007943A CN 201010532857X A CN201010532857X A CN 201010532857XA CN 201010532857 A CN201010532857 A CN 201010532857A CN 102007943 A CN102007943 A CN 102007943A
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aerosol
percent
dihydropyrone
repellant
tick
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CN102007943B (en
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何道航
刘仙平
周立新
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South China University of Technology SCUT
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South China University of Technology SCUT
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention discloses an aqueous tick repellent aerosol, which consists of the following raw materials in percentage by weight: 0.5 to 1 percent of dihydropyrone, 0.2 to 0.5 percent of radix peucedani volatile oil, 0.1 to 0.5 percent of mildew-proof agent, 0.8 to 7 percent of emulsifier, 10 to 16 percent of auxiliaries, 30 to 38 percent of propellant and 40 to 55 percent of de-ionized water. The aqueous tick repellent aerosol provided by the invention has the prominent advantages of achieving a remarkable repelling effect on ticks, reducing the release of volatile substances and pollutions to an environment, and avoiding irritation to skin, along with safety for humans, pets and the environment and relatively lower preparation cost, and is particularly suitable for use in travel and the use of field staff or marching troops.

Description

A kind of aqua type tick worm repellant aerosol
Technical field
Be specifically related to a kind of aqua type tick worm repellant aerosol, belong to household chemicals and health medicament field.
Background technology
Along with the change of global temperature rising and natural environment, the distribution of hematophagus enlarges, density raises, and is increasing to the harm that the field man causes.Using efficient repellant to protect, is to reduce the effective means that hematophagus is caused mechanical damage to the people and reduces the insect-borne diseases incidence of disease.More the whole nation was economized the deadly incident of tick sting was taken place this year, caused people's fear.
Tick belongs to Parasitiformes, Ixodides, and Ixodoidea comprises hard tick section, soft ticks section and receives tick section, kind surplus the world known 850.Kind surplus the kind of the known tick of China has 110 at present comprises soft ticks and hard tick two classes, and wherein majority can be invaded human body.Common important harm kind has 14 kinds: (1) ixodes persulcatus.Mainly being distributed in northeast, Xinjiang and Tibet in China, is the pathogene preserver and the main communication media of tick-borne encephalitis, also is the communication media of Lyme disease.(2) Ixodes crenulatus.Mainly being distributed in northeast, the Inner Mongol, northwest and Tibet in China, is one of preserver of yersinia pestis.(3) Haemaphysalis japonica.Mainly being distributed in northeast, Shanxi, Gansu and Qinghai in China, is the communication media of tick-borne encephalitis and Lyme disease.(4) Qinghai blood tick.Mainly being distributed in Ningxia, Gansu, Qinghai, Sichuan and Yunnan in China, is the communication media of sheep and goat Tai Shi texas fever.(5) haemaphysalis conicinna.Mainly being distributed in northeast, Xinjiang, the Inner Mongol and Shanxi in China, is the communication media of tick-borne encephalitis, Q heat, north Asia spotted fever, XHF.(6) dermacentor silvarum.Mainly being distributed in northeast, Shandong, Xinjiang, Hebei, the Inner Mongol and Shanxi in China, is that tick-borne encephalitis, Q heat, north Asia spotted fever and soil draw the communication media of logical sequence bacterium disease.(7) grassland leather tick.Mainly being distributed in northeast, North China, northwest and Yunnan in China, is the communication media of north Asia spotted fever and brucellosis.(8) China's leather tick.Mainly being distributed in northeast, North China, Shandong and Xinjiang in China, is the communication media of sheep and ox brucellosis.(9) Hyalomma asiaticum.Mainly being distributed in the Inner Mongol and northwest in China, is the communication media of XHF.(10) Hyalomma dctritum.Mainly being distributed in northeast, North China, Xinjiang, Shandong, Guizhou and Jiangsu in China, is the communication media of the annular Tai Shi texas fever of ox, also can carry the pathogene of Q heat and north Asia spotted fever.(11) boophilus microplus.Except that the some areas in northwest and northeast, all there is distribution other various places in China, are the communication medias of redwater fever.(12) brown dog tick.In the most of provinces and regions of China distribution being arranged all, is the communication media of north Asia spotted fever and Q heat.(13) adobe tick.Mainly being distributed in North China and northwest in China, is the communication media of Q heat.(14) ornithodoros lahorensis.Mainly being distributed in Gansu, Xinjiang and Tibet in China, is the communication media of Q heat.
Aerosol means that containing medicine is encapsulated in the pressure vessel with special valve system with the common dress of suitable propellant, during use, by the pressure of propellant content is the spray ejection.Mainly there is three types hygienic biocide aerosol in the market: oil base, tincture base, water base, promptly respectively with kerosene, alcohol and deionized water aerosol as solvent.All oil base more than 85% on China hygienic biocide aerosol market.Because oil base and tincture base aerosol all exist problems such as volatile organic matter VOCs (Volatile Organic Compounds), environmental pollution, toxicity and dispenser expense height, so less at some developed country's consumptions.There is the emission measure statute of limitation in EPA (EPA) to VOCs, and also there is control in Europe.The organic solvent that the aqua type aerosol distributes lacks than oil base, all having superiority aspect environmental protection, dispenser expense and the transportation, thereby the aqua type aerosol is replacing the oil base aerosol that contains organic solvent in the U.S., Japan and other countries.Along with the development of society, the raising of people's living standard, the continuous enhancing of environmental consciousness, the aqua type aerosol also will become the main product in China aerosol market.
Summary of the invention
The purpose of this invention is to provide a kind of, aqua type tick worm repellant aerosol that production cost relatively low good to tick worm repellent effect.
To achieve these objectives, the technical solution used in the present invention is:
A kind of aqua type tick worm repellant aerosol, by weight percentage, its composition of raw materials consists of: dihydropyrone 0.5-1%, root of purple-flowered peucedanum volatile oil 0.2-0.5%, mould inhibitor 0.1-0.5%, emulsifier 0.8-7%, auxiliary agent 10-16%, propellant 30-38% and deionized water 40-55%.
Be further to realize that the object of the invention, described mould inhibitor are preferably a kind of in sorbic acid and the Sodium Benzoate.
Described auxiliary agent is preferably ethanol.
Described propellant is preferably dimethyl ether.
Described emulsifier is preferably a kind of in single monoglyceride and the Sorbitan Oleate.
Mould inhibitor, auxiliary agent, propellant, emulsifier are this area preparation commonly used among the present invention, have no side effect.
Dihydropyrone, chemical name are 3,4-dihydro-2, and 2-dimethyl-4-oxo-2H-pyrans-6-butyl formate has the wide spectrum repellent action, and most hematophagus is had effect preferably.
Root of purple-flowered peucedanum volatile oil contains 50 number of chemical materials, and main component is australene, nopinene and caryophyllene.Concrete composition can be with reference to " GC/FTIR of root of purple-flowered peucedanum chemical composition of volatile oil analyzes " (Liu Buming, Zhang Huiling, imperial firm, " Guangxi chemical industry " the 1st phase of nineteen ninety-five).It is used for development as tick worm repellant (medical faunae control, 2002,18 (5): 234-235), grassland leather tick, Haemaphysalis japonica, Qinghai blood tick and brown dog tick are had biologically active preferably existing bibliographical information.
After testing, the aqua type tick worm repellant aerosol of the present invention's configuration has no side effect to the person poultry safety.
The active component of aqua type tick worm repellant aerosol provided by the invention includes dihydropyrone and root of purple-flowered peucedanum volatile oil, said composition has than remarkable role in synergy the repellent activity of tick worm, apparently higher than dihydropyrone repellant aerosol, this composite tick worm repellant aerosol is not seen the pertinent literature report to repellant aerosol after composite to the repellent activity of tick worm.
Compare with existing repellant aerosol, aqua type tick worm repellant aerosol provided by the invention has the following advantages:
(1) to the repellent obvious synergy of tick worm, all greater than 90%, the repellent percentage of 6h is up to 89.0% to the composite tick worm repellant aerosol of dihydropyrone and root of purple-flowered peucedanum volatile oil to the repellent percentage of tick worm 3h, and the repellent percentage behind the 9h is about 78%; And existing 0.7% dihydropyrone has only 85.3% to the repellent percentage of tick worm 3h.
(2) reduced the release of volatile organic matter, reduced pollution environment;
(3) to people, pet and Environmental security, non-stimulated to skin;
(4) the preparation production cost is lower, is suitable for especially travelling outdoors, field man or march army use.
Embodiment
For a better understanding of the present invention, the invention will be further described below in conjunction with embodiment, but the scope of protection of present invention is not limited to the represented scope of embodiment.
Embodiment 1:0.9% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol
Take by weighing dihydropyrone 0.50kg, root of purple-flowered peucedanum volatile oil 0.40kg, single monoglyceride 5.00kg and ethanol 10.00kg are stirred to the solution clarification in mixing still, add sorbic acid 0.10kg and deionized water 46.00kg again, stir, and make soup.
With capacity is that the aerosol jar of 400ml carries out bulk filling, and each is canned goes into above-mentioned soup 149g, installs spray valve, seal, in jar, charge into the 91g dimethyl ether with aerosol filling liquid filling machine, the spray lid is installed, promptly make 0.9% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol.
Embodiment 2:1.2% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol
Take by weighing dihydropyrone 1.00kg, root of purple-flowered peucedanum volatile oil 0.20kg, Sorbitan Oleate 7.00kg and ethanol 12.00kg are stirred to the solution clarification in mixing still, add Sodium Benzoate 0.50kg and deionized water 49.30kg again, stir, and make soup.
With capacity is that the aerosol jar of 400ml carries out bulk filling, and each is canned goes into above-mentioned soup 168g, installs spray valve, seal, in jar, charge into the 72g dimethyl ether with aerosol filling liquid filling machine, the spray lid is installed, promptly make 1.2% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol.
Embodiment 3:1.5% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol
Take by weighing dihydropyrone 1.00kg, root of purple-flowered peucedanum volatile oil 0.50kg, single monoglyceride 0.80kg and ethanol 16.00kg are stirred to the solution clarification in mixing still, add sorbic acid 0.20kg and deionized water 49.50kg again, stir, and make soup.
With capacity is that the aerosol jar of 400ml carries out bulk filling, and each is canned goes into above-mentioned soup 163g, installs spray valve, seal, in jar, charge into the 77g dimethyl ether with aerosol filling liquid filling machine, the spray lid is installed, promptly make 1.5% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol.
Embodiment 4:1.1% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol
Take by weighing dihydropyrone 0.80kg, root of purple-flowered peucedanum volatile oil 0.30kg, Sorbitan Oleate 1.9kg and ethanol 15.00kg are stirred to the solution clarification in mixing still, add Sodium Benzoate 0.40kg and deionized water 48.60kg again, stir, and make soup.
With capacity is that the aerosol jar of 400ml carries out bulk filling, and each is canned goes into above-mentioned soup 161g, installs spray valve, seal, in jar, charge into the 79g dimethyl ether with aerosol filling liquid filling machine, the spray lid is installed, promptly make 1.1% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol.
Embodiment 5:1.0% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol
Take by weighing dihydropyrone 0.55kg, root of purple-flowered peucedanum volatile oil 0.45kg, single monoglyceride 3.00kg and ethanol 11.00kg are stirred to the solution clarification in mixing still, add sorbic acid 0.30kg and deionized water 48.70kg again, stir, and make soup.
With capacity is that the aerosol jar of 400ml carries out bulk filling, and each is canned goes into above-mentioned soup 154g, installs spray valve, seal, in jar, charge into the 86g dimethyl ether with aerosol filling liquid filling machine, the spray lid is installed, promptly make 1.0% dihydropyrone root of purple-flowered peucedanum volatile oil aqua type tick worm repellant aerosol.
The repellent activity of tick worm repellant aerosol is measured
1, biological activity determination
The leggings that are installed with repellant dipping in a big case of raising grassland leather tick, stand respectively 3h, 6h and 9h, and to establish the leggings that do not flood repellant be experimental control, statistics is climbed to the grassland leather tick number on the leggings, calculate repellent percentage (with reference to Gertler et al (1962) method .J.Econ.Ent., 55 (4): 451)).
2, result's statistics and evaluation
The repellent activity measurement result of tick worm repellant aerosol sees Table 1.1.5% dihydropyrone root of purple-flowered peucedanum volatile oil aerosol agent derives from embodiment 3,1.1% dihydropyrone root of purple-flowered peucedanum volatile oil aerosol agent derives from embodiment 4,0.9% dihydropyrone root of purple-flowered peucedanum volatile oil aerosol agent derives from embodiment 1,1.3% dihydropyrone root of purple-flowered peucedanum volatile oil aerosol agent and 0.7% dihydropyrone root of purple-flowered peucedanum volatile oil preparation method are respectively referring to embodiment 2 and embodiment 1, and just consumption should become a little.
Table 1: tick worm repellant aerosol is measured the repellent activity of grassland leather tick
Figure BSA00000333500200061
Above-mentioned repellent activity measurement result shows, the composite tick worm repellant aerosol of dihydropyrone and root of purple-flowered peucedanum volatile oil to the repellent percentage of tick worm 3h all greater than 90%, the repellent percentage of 6h is up to 89.0%, repellent percentage behind the 9h is about 78%, by the data contrast as can be seen, the repellent activity of dihydropyrone and the composite repellant aerosol of root of purple-flowered peucedanum volatile oil obviously is better than single agent dihydropyrone repellant aerosol.Above data show that tick worm repellant aerosol provided by the invention not only has good repellent effect to the tick worm, and hold effect length, and the repellent time, more commercial repellant aerosol was long.In addition, tick worm repellant aerosol provided by the invention is to people's safety, and non-stimulated to skin, production cost is cheaper, is suitable for large-scale industrial production.

Claims (5)

1. aqua type tick worm repellant aerosol, it is characterized in that, by weight percentage, its composition of raw materials consists of: dihydropyrone 0.5-1%, root of purple-flowered peucedanum volatile oil 0.2-0.5%, mould inhibitor 0.1-0.5%, emulsifier 0.8-7%, auxiliary agent 10-16%, propellant 30-38% and deionized water 40-55%.
2. aqua type tick worm repellant aerosol according to claim 1 is characterized in that: described mould inhibitor is a kind of in sorbic acid and the Sodium Benzoate.
3. aqua type tick worm repellant aerosol according to claim 1, it is characterized in that: described auxiliary agent is an ethanol.
4. aqua type tick worm repellant aerosol according to claim 1, it is characterized in that: described propellant is a dimethyl ether.
5. aqua type tick worm repellant aerosol according to claim 1 is characterized in that: described emulsifier is a kind of in single monoglyceride and the Sorbitan Oleate.
CN201010532857XA 2010-11-03 2010-11-03 Aqueous tick repellent aerosol Expired - Fee Related CN102007943B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106490053A (en) * 2016-09-26 2017-03-15 塔里木大学 A kind of Tickss worm repellant medicament and preparation method thereof
CN111034729A (en) * 2019-12-30 2020-04-21 河南安进生物技术股份有限公司 Tick repellent, preparation method thereof and application thereof to tick repelling
JP2021054740A (en) * 2019-09-30 2021-04-08 エステー株式会社 Mite repellant and mite repelling method
JP2021054741A (en) * 2019-09-30 2021-04-08 エステー株式会社 Mite repellant and mite repelling method

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106490053A (en) * 2016-09-26 2017-03-15 塔里木大学 A kind of Tickss worm repellant medicament and preparation method thereof
JP2021054740A (en) * 2019-09-30 2021-04-08 エステー株式会社 Mite repellant and mite repelling method
JP2021054741A (en) * 2019-09-30 2021-04-08 エステー株式会社 Mite repellant and mite repelling method
CN111034729A (en) * 2019-12-30 2020-04-21 河南安进生物技术股份有限公司 Tick repellent, preparation method thereof and application thereof to tick repelling

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