CN104054732B - Agricultural acaricides aqueous suspension agent composition - Google Patents
Agricultural acaricides aqueous suspension agent composition Download PDFInfo
- Publication number
- CN104054732B CN104054732B CN201410288782.3A CN201410288782A CN104054732B CN 104054732 B CN104054732 B CN 104054732B CN 201410288782 A CN201410288782 A CN 201410288782A CN 104054732 B CN104054732 B CN 104054732B
- Authority
- CN
- China
- Prior art keywords
- mite
- aqueous suspension
- suspension agent
- agent composition
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention provides a kind of agricultural acaricides aqueous suspension agent composition, specifically comprise following component: 10～40%A component, 10～40%B component, 1 ~ 8% surfactant, 0.5 ~ 2% stabilizing agent, 1～3% synergist, 5～10% NMFs, 0.1～0.5% defoamer, 0.01～3% derivant, surplus is water, A component is second mite azoles, B component is Bifenazate, several compositions of one in pyridaben. Special structural stabilizing agent and biology revulant are screened, can effectively improve the preventive effect to tetranychid, high molecular surfactant forms polymeric membrane on target surface, and active matter molecule is embedded in polymeric membrane, control it and slowly discharge, avoid causing by force poisoning owing to penetrating; The derivant that meets tetranychid biological property can increase feed frequency, to increase acaricidal absorption, is conducive to control the harm of mite. This formulation principle uniqueness, production and processing is simultaneously simple, and stable in properties is applicable to suitability for industrialized production.
Description
Technical field
The present invention relates to technical field of pesticide, be specifically related to a kind of agricultural acaricides aqueous suspension agent composition.
Background technology
Along with organic agriculture, the development of industrialized agriculture, people are more and more higher to the attention degree of food security, how to improveThe service efficiency of agricultural chemicals, the use amount of reduction agricultural chemicals, and then reduction agricultural chemicals is current pesticide technology work the residual of agricultural productOne of top priority of person. Water base property suspending agent specifies to be subject to society in Environmental security and pays much attention to strict today. In recent years,China's water baseization agricultural chemicals has had certain development. Existing market is generally the aqueous suspension of second mite azoles and Bifenazate, in order to improveSecurity to crop, strengthen effect, reduce packing cost, by studying the mechanism of action of its combination, provide a kind of uniquenessFormulation principle and explained hereafter suspending agent.
Second mite azoles: English name Etoxazole is the special knot of the brand-new tool of one of SUMITOMO CHEMICAL KCC research and developmentThe acaricide of structure, molecular formula: C21H23F2NO2 molecular weight: 359.4096CAS:153233-91-1. Second mite azoles belongs to twoOxazolyl phenyl quinoline derivant, sterling outward appearance is white crystalline powder, fusing point: 101.5～102.5 DEG C; 293 DEG C of decomposition temperatures; SteamAir pressure (25 DEG C): 7.0 × 10-6Pa; N-octyl alcohol/water KowLogP=5.59 (25 DEG C); Solubility (g/L, 20 DEG C): in water7.04 × 10-5, in acetone 309.4, in methyl alcohol 104.0, in dimethylbenzene 251.7. The embryo that second mite azoles suppresses mite ovum form andFrom young mite to the process of casting off a skin that becomes mite, effective to ovum and young mite, to becoming mite invalid, but have well sterile to female one-tenth miteEffect. Therefore the control time of its best is the evil mite harm initial stage.
Bifenazate: English name BIFENAZATE, No. CAS: 149877-41-8, chemical name: 3-(4-methoxyl group connectionPhenyl-3-yl) carbazic acid isopropyl ester, molecular formula: C17H20N2O3, molecular weight: 300.35, its sterling outward appearance is whiteSolid crystal, molten point is 121.5～123.0 DEG C; Vapour pressure (25 DEG C): 3.8 × 10-7Pa; Solubility (20 DEG C): in water be2.1mg/L; In organic solvent (g/L): in toluene 24.7, in ethyl acetate 102, in methyl alcohol 44.7, in acetonitrile 95.6; Divide dispositionNumber (n-octyl alcohol/water): LogPow=3.5.
Bifenazate chemical structural formula
The former medicine of Bifenazate is to rat acute per os, equal through skin LD50 > 5000mg/kg, acute suction people LC50 >/L; To rabbitEyes, skin nonirritant: guinea pig skin sensitization test (STT) result is without sensitization. The sub-chronic feeding trial result of rat 90dLarge action-less dose: male rat be/kgd. female rats is /kgd; 4 mutagenicity tests: Salmonella reversion test, micronucleus examinationTest, external mammalian genes mutant test, external mammal chromosomal aberration test be all negative, have no mutagenesis and doWith. Bifenazate 480 grams per liter suspending agents to rat acute through ElLD50 > 5000mg/kg, acute through skin LD50 > 2000mg/Kg, acute suction 2LLC ∞ > 2mg/L; To rabbit skin nonirritant, lagophthalmos eyeball is irritant, but corrosion-free effect: guinea pig skin withoutSensitization.
Bifenazate 480 grams per liter suspending agents to rainbow trout 96h /L, zebra fish 96h /L; Quail LD50 (7d) is/Kg; Honeybee 48h acute oral LD50 > 110 μ ga.i./honeybees, acute contact LD50 > μ ga.i./; Silkworm LD50 in two ages is /kg.Said preparation is for apple tree, to the high poison of fish, high risk; To the medium poison of bird, low-risk; To honeybee, silkworm low toxicity, low windDangerous. When use, should note away from water body dispensers such as river embankments, forbid cleaning spraying apparatus in river embankment.
Bifenazate is a kind of new selective foliar spray acaricide. Its mechanism of action is the nervous centralis to mite classThe unique effect of one aminobutyric acid (GABA) acceptor of conducting system. Its each life stage to mite is effective, has ovicidal and livesProperty is knocked down activity (48～72h) with to what become mite, and the lasting period is long. Lasting period 14d left and right, recommendation dosage range is interior to doingThing safety. To parasitic wasp, Predatory Mites, Chrysopa low-risk.
For apple and grape control European red mite, Tetranychus urticae and McDaniel mite, and two spots of ornamental plantTetranychid and Lewis mite.
Pyridaben: the chemical name 2-tert-butyl group-5-(4-tert-butyl group benzylthio)-4-chlorine pyridazine-3-(2H) ketone, English nameClaim: 2-tert-butyl-5-(4-tert-butylbenzylthio)-chloropyridazin-3 (2H)-3-one; RelativelyMolecular weight 364.9, density 1.2 (20 DEG C), fusing point (DEG C) 111～112, vapour pressure (Pa) 0.25mPa (20 DEG C), solubility (20DEG C): water 0.012mg/L, acetone 460g/L, benzene 110g/L, cyclohexane 320g/L, ethanol 57g/L, n-octyl alcohol 63g/L, hexane10g/L, dimethylbenzene 390g/L. Appearance colorless crystal, toxicity LD50 (mg/kg), white mouse acute oral 1350 great and mighty or powerful, female big white mouse820, male small white mouse 424, female small white mouse 383. Big white mouse and rabbit are acute is greater than 2000 through skin. To lagophthalmos eyeball and the non-stimulated work of skinWith, to guinea pig skin without anaphylaxis. In what micronucleus test (mouse) of chromosomal aberration test (Chinese hamster) without mutagenicity. QuailQuail acute oral is greater than 2250, and wild duck acute oral is greater than 2500. Efficient, wide spectrum acaricide, without interior absorption, to tetranychid, completePawl mite, unguiculus mite are closed the planting property of food such as goitre mite evil mite and all have obvious prevention effect, and if to ovum mite, become mite all effective, to becomingThe mobile phase of mite is also effective. Be applicable to citrus, apple, pears, hawthorn, cotton, tobacco, vegetables (except eggplant) and ornamental plant.Stability: at 50 DEG C of stable 90d; At pH4,7,9, stable in organic solvent; To photo-labile
Red spider (Tetranychuscinnbarinus), Tetranychus urticae (Tetranychusurticae), full pawl leafMite (Panonychusulmi (Koch) Europeanredmite), ZhuSand tetranychid (Tetranychuscinnabarinus) etc. is the main mite class harming the crops, and belongs to Arthropoda, the animal kingdom,Not Arachnoidea, Acarina, Tetranychidae not of the same race. It is widely distributed, and feeding habits are assorted, can endanger 110 various plants. Main absorption plantThe juice of cauline leaf, makes its withered and yellow death, due to the three-dimensional-structure of its cryptomere, has chaeta, and control is difficulty comparatively, becomes danger in recent yearsOne of primary pest of evil crops.
At present, the Main Means of its control is had to chemical pesticide control method, the anti-therapy of biological natural enemy, mainly with chemical pesticideControl is main, with AVM, and pyridaben, clofentezine, fenpyroximate, second mite azoles, the single dose of Bifenazate etc. and complex preparation areActive component. Generally only having tetranychid and most acaricides to occur directly to contact just can be killed. , with other classThe agricultural pests of type are compared, and the activity of tetranychid is relatively few, mainly at leaf back cluster, therefore, unless used quite a large amount of upperState acaricide and cover completely guaranteeing, tetranychid is difficult for directly contacting with the acaricide of using. But traditional Prevention Technique and thinkingBe to increase dosage, increase bleeding agent, by the cooperative effect of compound synergic, and develop the new highly active chemical combination that hasThing, but its effect and means are extremely limited, except a large amount of above-mentioned acaricides can cause obvious waste, and repeatedly heavy dose ofUse above-mentioned acaricide and can accelerate the development of tetranychid resistance, the useful result that these technical measures obtain is cancelled. PatentCN102017960B, CN101999382B has proposed two compositions with acaricidal activity by compound synergic, leads according to agricultural chemicalsMissible oil is manufactured in the routine techniques measure in territory, dispersibles the method for oil suspending agent, and its core is utilized two compound compound synergicsPrinciple, the conventional art measure that it adopts still needs the technological deficiencies such as petrochemical industry organic solvent, and the utilization rate of agricultural chemicals is not improvedAnd raising.
Fujian agriculture academy of sciences website, Chinese Academy of Agricultural Sciences website has successively reported that Ying Geer company tea insects lures worm" insect pheromone " insect of the diligent joint development of the old ancestor of colour table technology and member of Chinese Academy of Engineering is administered technology, is to lure by releaseBionical insect pheromone in core, lures trapper (or viscose board) adult pest, and kills by the method for physics, therebyReduce insect and raise up seed, but that this technology is quoted is with high costs, be only suitable for the industrial crops of high added value, the kind of pest controlSingle, still cannot solve the problem of field crop harmful organism outburst harm.
Summary of the invention
In order to overcome the shortcoming of prior art, in order to overcome above-mentioned the deficiencies in the prior art, the invention provides a kind of agriculturalAcaricide aqueous suspension agent composition, and aqueous suspension agent composition and the production technology thereof of synergist and derivant. And with listOnly or simple composite usage acaricide is compared, and said composition is to sensitivity and resistance is female and the prevention effect of male tetranychid is obviously carriedHigh.
The technical solution that this practicality invention adopts is:
A kind of agricultural acaricides aqueous suspension agent composition, by mass percentage, specifically comprises following component: 10～40%A component, 10～40%B component, 1 ~ 8% surfactant, 0.5 ~ 2% stabilizing agent, 1～3% synergist, 5～10% NMFs,0.1～0.5% defoamer, 0.01～3% derivant, surplus is water.
Described agricultural acaricides aqueous suspension agent composition, described A component is second mite azoles, described B component is biphenylHydrazine ester, several compositions of one in pyridaben.
Described agricultural acaricides aqueous suspension agent composition, described derivant is pheromones, be specially nerolidol andThe spiceleaf tertiary alcohol.
Described agricultural acaricides aqueous suspension agent composition, described stabilizing agent is disodium ethylene diamine tetraacetate, the swelling of lithium baseOne or several compositions in soil, sodium pyrophosphate, carbendazim, Bravo and Kathon CG.
Described agricultural acaricides aqueous suspension agent composition, described synergist is oleic acid, linoleic acid, palm oil, sucrose,Glucose, maltose, one or several compositions in fructose.
Described agricultural acaricides aqueous suspension agent composition, described NMF is glycerine, propane diols, polyethylene glycol(400) one or several compositions in.
Described agricultural acaricides aqueous suspension agent composition, described surfactant is: Tea Saponin, desugar lignin sulfonic acidSodium (R85A), naphthalene sulfonate (D500), phosphate, modified polycarboxylic acid salt (LAB-3), bisphenol-A (STR-B), fatty alcohol polyoxy secondAlkene ether NMF, one or several compositions in polyethylene glycol (1000～4000).
The invention has the beneficial effects as follows: the invention provides a kind of agricultural acaricides aqueous suspension agent composition, for controllingWith the harm of control tetranychid to agriculture field, have advantages of following:
1, its coefficient of synergism is 2.1, belongs to notable synergistic;
2, its second mite azoles and Bifenazate or the selected formulation of pyridaben composition are aqueous suspension agent, without any organic petrochemical industrySolvent, belongs to the one of environment protection water-based agent type, in water, automatically disperses, and in suspension, active ingredient diameter of particle is 0.1Between～10 microns, be conducive to stick together on target crop, particle diameter is too large, is unfavorable for that target sticks together absorption, makes active ingredientWaste is serious;
3, sucrose, glucose, maltose, fructose is one of nutriment of tetranychid feed; Derivant be nerolidol andThe spiceleaf tertiary alcohol is tetranychid derivant, by combining with acaricide, can induce uptake and the suction of tetranychid to acaricidal activity compositionGet probability, kill mite efficiency thereby increase;
4, desugar sodium lignin sulfonate (R85A), naphthalene sulfonate (D500), phosphate, modified polycarboxylic acid salt (LAB-3),Bisphenol-A (STR-B), AEO NMF, the high molecular surfactants such as polyethylene glycol (1000～4000) canCan form monomolecular film at plant surface, active matter molecule parcel, be embedded in macromolecule molecule film, protective plant blade not bySucking of tetranychid, has extended the lasting period;
5, a kind of plant source surfactant of biogenic synergist Tea Saponin itself has the mite of killing, sterilization, insecticidal activity;Appropriate carbendazim and Bravo and Kathon CG have wide spectrum antimycotic antiseptic effect, can effectively suppress aqueous suspension agent preparation and go mouldy and repairTetranychid sucks the plant leaf blade wound causing, and avoids the immersion of harmful germ;
6, in suspending agent, introduce the principle of its NMF, can absorb and delay the moisture evaporation of liquid in crop surface,Extend the action time of medicament, improved drug effect; Be conducive to reduce tetranychid simultaneously and plant leaf blade endangered to the moisture damage causingLose, under the prerequisite of equal drug effect, reduced the dosage 20% of unit are.
Detailed description of the invention
A kind of agricultural acaricides aqueous suspension agent composition, by mass percentage, specifically comprises following component: 10～40%A component, 10～40%B component, 1 ~ 8% surfactant, 0.5 ~ 2% stabilizing agent, 1～3% synergist, 5～10% NMFs,0.1～0.5% defoamer, 0.01～3% derivant, surplus is water.
Described A component is second mite azoles, and described B component is Bifenazate, several compositions of one in pyridaben.
Described derivant is pheromones, is specially nerolidol and the spiceleaf tertiary alcohol. This material can improve male tetranychidThe motor behavior of nature, instinct, result increases random motion probability, and its motion can consume increase, at its carbohydrateUnder the luring of nutriment, the probability of its feed increases equally, has improved above-mentioned male tetranychid and has been combined in miticide compositionThe possibility that acaricide directly contacts has also improved acaricidal effect.
Described stabilizing agent is disodium ethylene diamine tetraacetate, lithium bentonite, sodium pyrophosphate, carbendazim, Bravo and Kathon CGIn one or several compositions. Disodium ethylene diamine tetraacetate and sodium pyrophosphate can with former medicine and other auxiliary materials in middle heavy metalIon complexation, forms chelate, reduces the impact of suspending agent particulate current potential, forms stable colloidal solutions; Lithium bentonite is onePlant thixotropic agent and the thickener of excellent performance; Be beneficial to the suspensibility of preparation of the present invention, stablize dilution. Carbendazim and Bravo andKathon CG has wide spectrum antimildew disinfectant, can effectively suppress aqueous suspension agent preparation and goes mouldy and repair tetranychid and suck the plant leaf blade wound causingWound, avoids the immersion of harmful germ.
Described synergist is oleic acid, linoleic acid, palm oil, sucrose, glucose, maltose, a kind of in fructose orSeveral compositions. Sucrose, glucose, maltose, fructose etc. are one of nutriments of tetranychid feed, by combining with acaricide,Can induce tetranychid to the uptake of acaricidal activity composition and draw probability, killing mite efficiency thereby increase.
Described NMF is glycerine, propane diols, one or several compositions in polyethylene glycol. Glycerine, the third twoAlcohol, polyethylene glycol is good NMF, is also antifreeze, and himself easily absorbs moisture in air, and volume increases, and extensively shouldFor household chemicals field. Spraying application to after plant leaf blade, can absorb airborne moisture, is that blade maintenance is moistening, reduces due to leafMite sucks the extent of injury of the leaf water volatilization causing.
Described surfactant is: Tea Saponin, desugar sodium lignin sulfonate, naphthalene sulfonate, phosphate, modified polycarboxylic acidSalt, bisphenol-A, AEO, one or several compositions in polyethylene glycol. All belong to macromolecule or ShuangziThe surfactant of type structure, in suspending agent process of lapping, forms parcel winding arrangement with acaricidal activity composition particulate, due toThe difference of polarity, solia particle repels mutually, hinders its cohesion and sedimentation, after dilution sprays application on plant leaf blade, formsPolymeric membrane, protective plant blade is sucking by tetranychid not.
Below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment 1:
10% second mite azoles, 40% Bifenazate, 3% phosphate, 2% AEO, 1% lithium bentonite, 0.2%Kathon CG, 3% fructose, 5% propane diols, 0.5% defoamer, the 2% spiceleaf tertiary alcohol, surplus is water.
Embodiment 2:
10% second mite azoles, 30% pyridaben, 0.5% phosphate, 0.5% AEO, 1.2% lithium bentonite,0.3% Kathon CG, 3% glucose sugar, 10% propane diols, 0.5% defoamer, the 3% spiceleaf tertiary alcohol, surplus is water.
Embodiment 3:
10% second mite azoles, 20% pyridaben, 10% Bifenazate, 3% bisphenol-A, 1% AEO, 1% Tea Saponin,0.2% lithium bentonite, 0.3% Bravo, 3% sucrose, 5% glycerine, 0.5% defoamer, 3% nerolidol, surplus is water.
Embodiment 4:
20% second mite azoles, 20% pyridaben, 3% bisphenol-A, 1% AEO, 1% cetomacrogol 1000,0.8% lithiumBase bentonite, 0.3% Bravo, 2% maltose, 6% glycerine, 0.5% defoamer, 2% nerolidol, surplus is water.
Embodiment 5:
40% second mite azoles, 10% pyridaben, 3% bisphenol-A, 1% AEO, 1% cetomacrogol 1000,0.8% lithiumBase bentonite, 0.3% carbendazim, 1% maltose, 3% PEG400,0.5% defoamer, 1% nerolidol, surplus isWater.
Embodiment 6:
10% second mite azoles, 20% Bifenazate, 3% bisphenol-A, 1% AEO, 1% Macrogol 2000,0.8%Lithium bentonite, 0.3% Bravo, 1% maltose, 8% glycerine, 0.1% defoamer, 2% nerolidol, surplus is water.
Embodiment 7:
10% second mite azoles, 30% Bifenazate, 3% desugar sodium lignin sulfonate, 1% AEO, 1% poly-second twoAlcohol 3000,1% lithium bentonites, 0.1% Kathon CG, 1% maltose, 10% propane diols, 0.3% defoamer, 0.1% nerolidol,Surplus is water.
Embodiment 8:
15% second mite azoles, 25% Bifenazate, 3% modified polycarboxylic acid salt, 1% AEO, 1% polyethylene glycol2000,0.8% lithium bentonites, 0.3% Bravo, 1% glucose, 5% glycerine, 0.5% defoamer, 0.5% nerolidol,Surplus is water.
Embodiment 9:
10% second mite azoles, 10% Bifenazate, 6% modified polycarboxylic acid salt, 1% AEO, 1% polyethylene glycol6000,1.5% lithium bentonites, 0.5% disodium ethylene diamine tetraacetate, 1% palm oil, 5% glycerine, 0.5% defoamer, 0.5%Nerolidol, surplus is water.
Embodiment 10:
10% second mite azoles, 20% Bifenazate, 6% Tea Saponin, 1% AEO, 1% Macrogol 6000,1.2%Lithium bentonite, 0.8% sodium pyrophosphate, 1% linoleic acid, 10% propane diols, 0.5% defoamer, 0.01% nerolidol, surplus isWater.
Embodiment 11:
10% second mite azoles, 10% Bifenazate, 6% naphthalene sulfonate, 1% AEO, 1% Macrogol 2000,1.5% lithium bentonite, 0.5% sodium pyrophosphate, 1% oleic acid, 10% glycerine, 0.5% defoamer, 0.5% nerolidol, surplusFor water.
Embodiment 12:
25% second mite azoles, 25% Bifenazate, 5% phosphate, 2% AEO, 1% Macrogol 2000,0.8%Lithium bentonite, 1% sodium pyrophosphate, 0.2% Kathon CG, 1% glucose, 5% glycerine, 0.5% defoamer, 0.5% nerolidol,Surplus is water.
Test of pesticide effectiveness part:
Example of the present invention is to adopt method indoor and that field control effectiveness test combines.
One, indoor pharmacodynamic test
1.1 for test-object target
Citrus red mite (PanonychuscitriMcGregor), continuously subculture raised for 2 generations, and raising temperature is 23～30 DEG C, natural lighting, chooses female one-tenth mite of the same size as examination worm.
1.2 training instrument and equipments
Illumination box (Guangdong medical apparatus and instruments factory), electronic balance (the flat instrument plant of upper current chart), culture dish, beaker, graduated cylinder,Writing brush, filter paper, tweezers etc.
2, experimental design
2.1 experimental pharmacy
The former medicine of 96% second mite azoles, the former medicine of 95% pyridaben, the former medicine of 97% Bifenazate, acetone, Tween 80 etc. By above-mentioned former medicineMake aqueous suspension agent according to example ratio, be respectively example 1, example 2, example 5, example 7, example 10.
2.2 dosage settings
According to preliminary experiment result, by former to second mite azoles, Bifenazate and pyridaben medicinal acetone solution, with containing 0.1% tween80 distilled water solutions dilutions, second mite azoles and pyridaben set handling concentration 6,3,1.5,0.75,0.375,0.1875mg/L, biphenylThe concentration for the treatment of of hydrazine ester is 64,32,16,8,4,2mg/L, and the direct dilute with water of example 1,2,5,7,10, set handling concentration are20,10,5,2.5,1.25,0.625mg/L. Each concentration for the treatment of is established four repetitions, each repeat to be no less than 20 become mites.
3 test methods
The slide infusion process that adopts FAO to recommend. Two-sided tape is affixed on to slide one end, then use No. 0 writing brush nib fromFor the female one-tenth mite of picking on mite blade, mite back is affixed on to Jiao Mianshang, every slide at least pastes more than 30, will post carrying of miteSlide is placed in the culture dish of interior end liner moisturizing filter paper, after 2h, expands microscopy with binocular, and all mite foots motionless person reject with needle point, soRear with medicament is processed.
4, cultivate
The slide that has mite good chemicals treatment is put in the culture dish of interior subgaskets moisturizing filter paper, is placed in 26 ± 1 DEG C,Illumination 14h/d, cultivates in the growth cabinet that RH is 55%～70%.
5 data surveys and statistical analysis
5.1 investigation method
48h microscopy record mite number anyway after processing. Death standard: touch mite foot taking writing brush point and do not move person as dead.
5.2 death rates are calculated
The death rate (%)=dead borer population/examination borer population × 100
Correct the death rate (%)=(the processed group death rate-control group death rate)/(100-control group death rate) × 100
5.3 Virulent Analysis
Utilize Agricultural University Of Nanjing's biological activity determination analysis software and Excel, set up each medicament virulence regression equation,Calculate LC50Value, LC90With 95% confidence limit.
5.4 mixed agent co-toxicity coefficients calculate and synegism evaluation
Adopt the abundant method of Sun Yun (1960) to evaluate mixed agent synergistic effect. Calculate the co-toxicity coefficient of mixed agent according to following formula（CTC）：
Mixed agent co-toxicity coefficient (CTC)=[actual measurement toxicity index (ATI)/theoretical toxicity index (TTI)] × 100
Actual measurement toxicity index (ATI)=(LC of standard medicament50The LC of/reagent agent50）×100
Content (the %)+B agent toxicity index of the theoretical toxicity index of mixture (TTI)=A agent toxicity index × A agent in mixture ×The content (%) of B agent in mixture
It is synergistic effect that co-toxicity coefficient is significantly greater than at 100 o'clock, approaches or be slightly less than 100 for summation action, is significantly less than 100For antagonism.
6 test results and analysis
The virulence of 6.1 single doses to citrus red mite
The toxicity test result of single dose shows, second mite azoles is relatively higher than Bifenazate to the virulence of citrus red mite larvaVirulence, the former virulence is 2.76 times of the latter. 48h after medicine, the LC of second mite azoles to citrus red mite50For 0.89mg/L, LC90For7.21mg/L, the LC of Bifenazate50For 9.03mg/L, LC90For 64.43mg/L(is in table 1)6.2 mixtures pairThe virulence of citrus red mite
Second mite azoles Bifenazate or the second mite azoles Damanling suspension agent mixture pair of 5 different proportionings are measured respectivelyThe virulence of citrus red mite. Result shows, second mite azoles and equal to the virulence of citrus red mite with the mixture of pyridaben BifenazateHigher than Bifenazate, pyridaben and second mite azoles single dose. In 5 measured proportioning mixtures, virulence height is followed successively by: mixture 3> mixture 1# > mixture 2# > mixture 4# > mixture 5#; Be wherein second mite azoles: Bifenazate=1:10 with mixture 3#() to citrus red miteVirulence the highest, its LC50For 2.59mg/L, LC90For 20.07mg/L; Minimum to the virulence of citrus red mite with mixture 5#, itsLC50For 4.32mg/L, LC90Reach 41.77mg/L. The virulence of mixture 3# is significantly higher than other mixtures (be shown in table 2).6.3 mixtures are to the red spider of citrusThe co-toxicity coefficient of spider
Co-toxicity coefficient (CTC) result of calculation of the each mixture of second mite azoles Bifenazate to citrus red mite shows, institute measures5 proportioning mixtures to the CTC of citrus red mite is all greater than to 130(in table 3), this explanation second mite azoles and Bifenazate mixture,Citrus red mite is all had to synergistic effect. Wherein, with mixture 3#(second mite azoles: Bifenazate=1:3) CTC value maximum, reach190.17, synergistic effect reaches the utmost point level of signifiance, and its co-toxicity to citrus red mite has improved 90.17%.
The aqueous suspension agent of 5 examples of measuring is all greater than 120 to the CTC of citrus red mite, shows obvious increasingEffect effect, shows that the combination water suspending agent of this invention can obviously improve drug effect.
Two, field control effectiveness test
2.1 experiment purpose
Testing the effect of composition aqueous suspension agent of the present invention oranges and tangerines control red spider, and evaluate its security, is thisInvention is promoted the use of foundation is provided.
2.2 experimental subjects
Experimental subjects: citrus red mite (PanonychuscitriMcg)
Experiment crop: mandarin tree (kind: red Jiang Cheng)
2.3 environmental condition
For trying orchard: 2 years Sheng Hongjiangcheng gardens, post line-spacing 1.5 × 2.5m, average plant height 1.1m, tree wide cut 1.05m, soil propertyFor red soil, PH4.2, the content of organic matter is general. Garden interplantation is by single, in the ranks plants and has green manure, and biofacies is simple, world kind andQuantity is few, and red spider occurs more serious, year medication number of times 5～7 times, experiment garden every strain sealing fertilizer 0.1kg on March 3.
3, experimental design and arrangement
3.1 experimental pharmacy
Example 2, example 7(composition of the present invention)
3.2 contrast medicaments
110g/L second mite azoles SC (SUMITOMO CHEMICAL KCC), 430g/L (42%) Bifenazate suspending agent (section of the U.S.Ju Ya company)
3.3 dosings and numbering
3.4 community experiments
Random alignment is taked in community experiment, and, for 2 strains of examination tree, repeat for four times every community.
3.5 application methods and apparatus
3.5.1 adopt spray-on process. Each processing dilution is dripped the moistening wish of spraying for the even blade face of examination tree, blade back.
3.5.2 with the super green 16 type knapsack sprayer conventional spray of MATABI. Approximately 3 atmospheric pressure of sprayer operating pressure,Spray orifice bore 1mm, an injection flow rate 500ml/3 atmospheric pressure per minute, spray diameter 80-100um, spraying swath 1～1.2m.
3.6 spraying times and number of times
Dispenser once. When May medication on the 15th, if red spider becomes, young mite and the each worm state of ovum all have generation, if wherein with, childrenMite is main, and mite ovum ratio is: 1:1.08.
3.7 use capacity
1500 liters of per hectare water consumptions.
4 investigation, record and measuring method
4.1 meteorological data
Dispenser same day, fine day, 31 DEG C of temperature, 1 grade of south wind, 19.2～26.6 DEG C of daily mean temperatures, relative humidity 75～95%。
4.2 search into a matter and number of times
Investigation insect population radix before medicine, after medicine, 3d, 10d, the each investigation of 15d, 20d are once.
4.3 investigation method
On for the strain of examination tree, by east, south, west, north, in 5 points, every one is slightly, often slightly investigates 5 blades, adjust altogether every communityLook into 50 blades, record the mite number of living.
4.4 drug effect computational methods
Prevention effect (%)=[1-(CK0XPT1/CK1XPT0)]×100
PT0Borer population alive before chemicals treatment district medicine
PT1Borer population alive after chemicals treatment district medicine
CK0XBorer population alive before the trivial medicine of blank
CK1XBorer population alive after the trivial medicine of blank
4.5 results and analysis
Experiment adopts " DMRT " method to analyze the significance of difference between each processing. Application software is DPS2000 data processing systemSystem.
Evaluating drug effect
Experimental result shows: if containing the composition of the present invention of synergist and attractant for examination concentration to becoming, young mite is equalHave good preventive effect, its synergistic function is obvious, and quick-acting is good, and after medicine, 3d preventive effect can reach 93.8%, to the preventive effect of mite ovumAlso good, the lasting period is long, under for examination concentration conditions, field red spider is effectively controlled more than the phase can reach 20d; To the full pawl leaf of oranges and tangerinesMite, the beginning tetranychid, embroider spider, Polyphagotarsonemus latus Banks has preventive and therapeutic effect equally. And other common acaricides are produced to resistanceRed spider effect, and be difficult for and the conventional acaricide generation cross resistance using, be ideal killing on current Orange ProducingMite agent. Use single medicament in the long-term continuous several times of the same area, improving constantly of same medicament working concentration, has accelerated tetranychidDrug-fast generation, under action of agricultural chemicals of the same race, can induce tetranychid (red spider) to produce variation on the one hand, occurs new anti-medicineType; On the other hand, because the selection pressure of agricultural chemicals, the resistance to the action of a drug originally existing in target colony will accumulate gradually, causesAnti-pharmacopoeia group becomes the dominant population of whole colony, thereby affects acaricidal result of use. Above-mentioned indoor and outdoors field medicineEffect test data explanation, acaricide composition of the present invention is at high molecular surfactant, derivant, synergist and NMFUnder synergy, drug effect is obviously better than the second mite azoles of identical component, Bifenazate single dose preventive effect, experimental results show that of the present invention joiningFang Yuanli uniqueness, rationally, production and processing technology is simple simultaneously, has obvious economical, societal benefits in combination.
Claims (4)
1. an agricultural acaricides aqueous suspension agent composition, is characterized in that, by mass percentage, specifically comprises following groupPoint: 10～40% second mite azoles, 10～40% Bifenazates or pyridaben, 1 ~ 8% surfactant, 0.5 ~ 2% stabilizing agent, 1～3% synergist, 5～10% NMFs, 0.1～0.5% defoamer, 0.01～3% derivant, surplus is water, described derivant isPheromones, is specially nerolidol and geraniol, and described synergist is oleic acid, linoleic acid, palm oil, sucrose, glucose, wheatBud sugar, one or several compositions in fructose.
2. agricultural acaricides aqueous suspension agent composition according to claim 1, is characterized in that: described stabilizing agent is second twoOne or several compositions in amine tetraacethyl disodium, lithium bentonite, sodium pyrophosphate, carbendazim, Bravo and Kathon CG.
3. agricultural acaricides aqueous suspension agent composition according to claim 1, is characterized in that: described NMF is thirdTriol, propane diols, one or several compositions in polyethylene glycol.
4. agricultural acaricides aqueous suspension agent composition according to claim 1, is characterized in that: described surfactantFor: Tea Saponin, desugar sodium lignin sulfonate, naphthalene sulfonate, phosphate, modified polycarboxylic acid salt, bisphenol-A, aliphatic alcohol polyethenoxyEther, one or several compositions in polyethylene glycol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410288782.3A CN104054732B (en) | 2014-06-25 | 2014-06-25 | Agricultural acaricides aqueous suspension agent composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410288782.3A CN104054732B (en) | 2014-06-25 | 2014-06-25 | Agricultural acaricides aqueous suspension agent composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104054732A CN104054732A (en) | 2014-09-24 |
| CN104054732B true CN104054732B (en) | 2016-05-11 |
Family
ID=51542892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410288782.3A Active CN104054732B (en) | 2014-06-25 | 2014-06-25 | Agricultural acaricides aqueous suspension agent composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104054732B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105613542A (en) * | 2016-01-19 | 2016-06-01 | 新疆锦华农药有限公司 | Synergistic acaricidal composition containing etoxazole and bifenazate |
| CN107136062B (en) * | 2017-06-16 | 2020-10-16 | 桂林集琦生化有限公司 | Mixture prepared by blending agricultural synergist, bifenazate and etoxazole compound and preparation and application thereof |
| CN107751192A (en) * | 2017-09-07 | 2018-03-06 | 京博农化科技股份有限公司 | Application of the trimethylglycine in pesticide suspension concentrate preparation |
| CN107535487A (en) * | 2017-09-07 | 2018-01-05 | 京博农化科技股份有限公司 | Application of the sweet amino proline of methyl in pesticide suspension concentrate preparation |
| CN110432267A (en) * | 2019-08-22 | 2019-11-12 | 西南大学 | A kind of auxiliary agent for preventing and treating tetranychid |
| CN113575577A (en) * | 2021-08-17 | 2021-11-02 | 京博农化科技有限公司 | Auxiliary agent combination for preparing suspending agent, flufenacet water suspending agent and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1125382A (en) * | 1993-04-30 | 1996-06-26 | 特洛伊生物科学公司 | Miticidal composition and method for controlling spider mite populations |
| CN101990893A (en) * | 2010-11-01 | 2011-03-30 | 吴明龙 | Pesticide composition containing etoxazole and pyridaben |
| CN101999382A (en) * | 2011-01-01 | 2011-04-06 | 陕西上格之路生物科学有限公司 | Mite-killing composition containing etoxazole and bifenazate |
| CN102017960A (en) * | 2011-01-01 | 2011-04-20 | 陕西上格之路生物科学有限公司 | Acaricidal composition containing etoxazole and pyridaben |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4382940B2 (en) * | 1999-12-22 | 2009-12-16 | 積水化学工業株式会社 | Mite attractant, acaricide and mite trapping material |
-
2014
- 2014-06-25 CN CN201410288782.3A patent/CN104054732B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1125382A (en) * | 1993-04-30 | 1996-06-26 | 特洛伊生物科学公司 | Miticidal composition and method for controlling spider mite populations |
| CN101990893A (en) * | 2010-11-01 | 2011-03-30 | 吴明龙 | Pesticide composition containing etoxazole and pyridaben |
| CN101999382A (en) * | 2011-01-01 | 2011-04-06 | 陕西上格之路生物科学有限公司 | Mite-killing composition containing etoxazole and bifenazate |
| CN102017960A (en) * | 2011-01-01 | 2011-04-20 | 陕西上格之路生物科学有限公司 | Acaricidal composition containing etoxazole and pyridaben |
Non-Patent Citations (1)
| Title |
|---|
| 增稠剂在农药水悬浮剂中的应用;冯建国 等;《今日农药》;20091231(第5期);第17-22页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104054732A (en) | 2014-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104054732B (en) | Agricultural acaricides aqueous suspension agent composition | |
| BR112020003643A2 (en) | miticide and concrete application | |
| CN102630691A (en) | Pesticide composition containing cyflumetofen | |
| CN102217615A (en) | Pesticide composition containing Spirotetramat and amide insecticides | |
| CN108041083B (en) | Plant source pesticide synergist and application thereof | |
| CN102986700A (en) | Insecticide composition containing flutenzine and bistrifluron | |
| CN103355322B (en) | Compound biological insecticide and application thereof | |
| CN102388873A (en) | Downy mildew fungicide for promoting crop growth and application thereof | |
| CN101406199A (en) | Insecticidal composition containing emamectin-benzoate | |
| CN103636621A (en) | Pesticide composition containing etoxazole and azadirachtin | |
| CN103168787A (en) | Insecticidal composition containing lufenuron and cyantraniliprole | |
| CN102960353A (en) | Insecticidal and acaricidal composition containing metaflumizone and flufenzine | |
| CN103548849B (en) | Synergistic compound biological bactericide and application thereof | |
| CN102246779A (en) | Pesticide composition containing spirotetramat and spinosad | |
| CN102204549A (en) | Insecticidal composition containing spirotetramat and fenpyroximate | |
| CN102246786A (en) | Pesticidal composition containing spirotetramat and metaflumizone | |
| CN109258716A (en) | A kind of composition pesticide and preparation method thereof | |
| CN103039467A (en) | Insecticidal composition containing flufenzine and spirotetramat | |
| CN113519565B (en) | Plant protection liquid | |
| CN102972416A (en) | Acaricidal composition containing fluacrypyrim and spirodiclofen | |
| CN108782573A (en) | The miticide composition and its application of D- limonenes and rotenone | |
| CN102273481B (en) | Dinotefuran-containing pesticidal composition | |
| CN102239858B (en) | Pesticide composition containing pyrimidifen and avermectins | |
| CN102228039A (en) | Pesticide composition containing spirotetramat and chlorfenapyr | |
| CN109392909A (en) | A kind of miticide composition containing fluorine pyrrole furanone and chlorfenapyr |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |