CN102006873B - 调整mc5受体活性的方法以及与这种受体相关的病况的治疗 - Google Patents
调整mc5受体活性的方法以及与这种受体相关的病况的治疗 Download PDFInfo
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- CN102006873B CN102006873B CN2009801130048A CN200980113004A CN102006873B CN 102006873 B CN102006873 B CN 102006873B CN 2009801130048 A CN2009801130048 A CN 2009801130048A CN 200980113004 A CN200980113004 A CN 200980113004A CN 102006873 B CN102006873 B CN 102006873B
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
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- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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| US3291208P | 2008-02-29 | 2008-02-29 | |
| US61/032,912 | 2008-02-29 | ||
| US12/391,748 US8377925B2 (en) | 2008-02-29 | 2009-02-24 | Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor |
| US12/391,748 | 2009-02-24 | ||
| PCT/AU2009/000231 WO2009105824A1 (en) | 2008-02-29 | 2009-02-27 | Methods of modulating the activity of the mc5 receptor and treatment of conditions related to this receptor |
Publications (2)
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| CN102006873A CN102006873A (zh) | 2011-04-06 |
| CN102006873B true CN102006873B (zh) | 2013-09-18 |
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| US8008291B2 (en) * | 2008-02-29 | 2011-08-30 | Mimetica Pty Ltd | 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5 receptor antagonists |
| EP2257533B1 (en) * | 2008-02-29 | 2013-09-18 | Mimetica Pty Limited | 3-substituted-1,4-diazepan-2-one melanocortin-5 receptor antagonists |
| EP3288534B1 (en) | 2015-04-28 | 2020-09-23 | Symrise AG | Compositions comprising valerian extracts |
| GB201808149D0 (en) | 2018-05-18 | 2018-07-11 | Univ Court Univ Of Glasgow | Protected amino acids |
| CN115381955B (zh) * | 2021-05-24 | 2024-05-17 | 中国科学技术大学 | 黑皮质素受体mc5r的用途 |
| CN114478210A (zh) * | 2022-02-26 | 2022-05-13 | 江苏壹药新材料有限公司 | 一种7-氯萘-2-甲醛的合成方法 |
| CN115232015B (zh) * | 2022-07-06 | 2024-01-02 | 暨明医药科技（苏州）有限公司 | 一种氯喹手性侧链的合成方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999048913A1 (en) * | 1998-03-24 | 1999-09-30 | The University Of Queensland | Peptide turn mimetics |
| CN1816337A (zh) * | 2003-05-01 | 2006-08-09 | 帕拉坦技术公司 | 黑素皮质素受体特异性化合物 |
| WO2008017852A1 (en) * | 2006-08-11 | 2008-02-14 | Palatin Technologies, Inc. | Diamine-containing, tetra- substituted piperazine compounds as melanocortin receptor modulators |
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| US6A (en) * | 1836-08-10 | Thomas Blanchard | Machine for forming end pieces of plank blocks for ships | |
| US8008291B2 (en) * | 2008-02-29 | 2011-08-30 | Mimetica Pty Ltd | 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5 receptor antagonists |
| EP2257533B1 (en) * | 2008-02-29 | 2013-09-18 | Mimetica Pty Limited | 3-substituted-1,4-diazepan-2-one melanocortin-5 receptor antagonists |
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2009
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999048913A1 (en) * | 1998-03-24 | 1999-09-30 | The University Of Queensland | Peptide turn mimetics |
| CN1816337A (zh) * | 2003-05-01 | 2006-08-09 | 帕拉坦技术公司 | 黑素皮质素受体特异性化合物 |
| WO2008017852A1 (en) * | 2006-08-11 | 2008-02-14 | Palatin Technologies, Inc. | Diamine-containing, tetra- substituted piperazine compounds as melanocortin receptor modulators |
Also Published As
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| IL207833A0 (en) | 2010-12-30 |
| EP2257297B1 (en) | 2017-10-18 |
| NZ587361A (en) | 2012-07-27 |
| CA2716316A1 (en) | 2009-09-03 |
| IL207833B (en) | 2018-02-28 |
| BRPI0907906A2 (pt) | 2020-08-18 |
| MX2010009488A (es) | 2011-03-02 |
| KR20100134614A (ko) | 2010-12-23 |
| JP2011513245A (ja) | 2011-04-28 |
| WO2009105824A1 (en) | 2009-09-03 |
| EP2257297A1 (en) | 2010-12-08 |
| CN102006873A (zh) | 2011-04-06 |
| CA2716316C (en) | 2017-05-30 |
| RU2555343C9 (ru) | 2015-11-27 |
| EP2257297A4 (en) | 2012-02-22 |
| RU2010137030A (ru) | 2012-04-10 |
| AU2009219107B2 (en) | 2013-11-21 |
| RU2555343C2 (ru) | 2015-07-10 |
| KR101620115B1 (ko) | 2016-05-12 |
| JP5503558B2 (ja) | 2014-05-28 |
| AU2009219107A1 (en) | 2009-09-03 |
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